1H64
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1H5X
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1M8U
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![BU of 1m8u by Molmil](/molmil-images/mine/1m8u) | Crystal Structure of Bovine gamma-E at 1.65 Ang Resolution | Descriptor: | gamma-E | Authors: | Mayer, C, Agueznay, N, Skouri-Panet, F, Prat, K, Putilina, T, Biarrotte-Sorin, S, Tardieu, A. | Deposit date: | 2002-07-26 | Release date: | 2003-08-05 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Crystal Structure of Bovine gamma-E To be Published
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4G3N
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![BU of 4g3n by Molmil](/molmil-images/mine/4g3n) | Mycobacterium tuberculosis gyrase type IIA topoisomerase C-terminal domain at 1.4 A resolution | Descriptor: | DNA gyrase subunit A | Authors: | Darmon, A, Piton, J, Petrella, S, Aubry, A, Mayer, C. | Deposit date: | 2012-07-15 | Release date: | 2013-08-07 | Last modified: | 2023-09-13 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Mycobacterium tuberculosis DNA gyrase possesses two functional GyrA-boxes. Biochem.J., 455, 2013
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4Q11
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![BU of 4q11 by Molmil](/molmil-images/mine/4q11) | Crystal structure of Proteus mirabilis transcriptional regulator protein Crl at 1.95A resolution | Descriptor: | 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, Sigma factor-binding protein Crl | Authors: | Norel, F, Mayer, C, Saul, F.A, Haouz, A. | Deposit date: | 2014-04-02 | Release date: | 2014-08-06 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural and functional features of Crl proteins and identification of conserved surface residues required for interaction with the RpoS/ sigma S subunit of RNA polymerase. Biochem.J., 463, 2014
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3ZM7
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![BU of 3zm7 by Molmil](/molmil-images/mine/3zm7) | CRYSTAL STRUCTURE OF THE ATPASE REGION OF Mycobacterium tuberculosis GyrB WITH AMPPCP | Descriptor: | DNA GYRASE SUBUNIT B, MAGNESIUM ION, PHOSPHOMETHYLPHOSPHONIC ACID ADENYLATE ESTER | Authors: | Agrawal, A, Roue, M, Spitzfaden, C, Petrella, S, Aubry, A, Volker, C, Mossakowska, D, Hann, M, Bax, B, Mayer, C. | Deposit date: | 2013-02-05 | Release date: | 2013-09-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Mycobacterium Tuberculosis DNA Gyrase ATPase Domain Structures Suggest a Dissociative Mechanism that Explains How ATP Hydrolysis is Coupled to Domain Motion. Biochem.J., 456, 2013
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3ZKD
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![BU of 3zkd by Molmil](/molmil-images/mine/3zkd) | CRYSTAL STRUCTURE OF THE ATPASE REGION OF Mycobacterium tuberculosis GyrB WITH AMPPNP | Descriptor: | DNA GYRASE SUBUNIT B, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Agrawal, A, Roue, M, Spitzfaden, C, Petrella, S, Aubry, A, Volker, C, Mossakowska, D, Hann, M, Bax, B, Mayer, C. | Deposit date: | 2013-01-22 | Release date: | 2013-09-18 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (2.95 Å) | Cite: | Mycobacterium Tuberculosis DNA Gyrase ATPase Domain Structures Suggest a Dissociative Mechanism that Explains How ATP Hydrolysis is Coupled to Domain Motion. Biochem.J., 456, 2013
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3ZKB
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![BU of 3zkb by Molmil](/molmil-images/mine/3zkb) | CRYSTAL STRUCTURE OF THE ATPASE REGION OF Mycobacterium tuberculosis GyrB WITH AMPPNP | Descriptor: | DNA GYRASE SUBUNIT B, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Agrawal, A, Roue, M, Spitzfaden, C, Petrella, S, Aubry, A, Volker, C, Mossakowska, D, Hann, M, Bax, B, Mayer, C. | Deposit date: | 2013-01-22 | Release date: | 2013-09-18 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Mycobacterium Tuberculosis DNA Gyrase ATPase Domain Structures Suggest a Dissociative Mechanism that Explains How ATP Hydrolysis is Coupled to Domain Motion. Biochem.J., 456, 2013
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3IG0
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3IFT
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![BU of 3ift by Molmil](/molmil-images/mine/3ift) | Crystal structure of glycine cleavage system protein H from Mycobacterium tuberculosis, using X-rays from the Compact Light Source. | Descriptor: | Glycine cleavage system H protein | Authors: | Edwards, T.E, Abendroth, J, Staker, B, Mayer, C, Phan, I, Kelley, A, Analau, E, Leibly, D, Rifkin, J, Loewen, R, Ruth, R.D, Stewart, L.J, Accelerated Technologies Center for Gene to 3D Structure (ATCG3D) | Deposit date: | 2009-07-25 | Release date: | 2009-08-11 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray structure determination of the glycine cleavage system protein H of Mycobacterium tuberculosis using an inverse Compton synchrotron X-ray source. J.Struct.Funct.Genom., 11, 2010
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3IFZ
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![BU of 3ifz by Molmil](/molmil-images/mine/3ifz) | crystal structure of the first part of the Mycobacterium tuberculosis DNA gyrase reaction core: the breakage and reunion domain at 2.7 A resolution | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, DNA gyrase subunit A, SODIUM ION | Authors: | Piton, J, Aubry, A, Delarue, M, Mayer, C. | Deposit date: | 2009-07-27 | Release date: | 2010-07-28 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural insights into the quinolone resistance mechanism of Mycobacterium tuberculosis DNA gyrase. Plos One, 5, 2010
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4O5T
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![BU of 4o5t by Molmil](/molmil-images/mine/4o5t) | Crystal structure of Diels-Alderase CE20 in complex with a product analog | Descriptor: | 4-{[2-(phosphonooxy)ethyl]carbamoyl}benzyl [(1R,6S)-6-(dimethylcarbamoyl)cyclohex-2-en-1-yl]carbamate, Diisopropyl-fluorophosphatase | Authors: | Beck, T, Preiswerk, N, Mayer, C, Hilvert, D. | Deposit date: | 2013-12-20 | Release date: | 2014-06-04 | Last modified: | 2023-11-08 | Method: | X-RAY DIFFRACTION (2.9 Å) | Cite: | Impact of scaffold rigidity on the design and evolution of an artificial Diels-Alderase. Proc.Natl.Acad.Sci.USA, 111, 2014
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4O5S
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6Z01
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![BU of 6z01 by Molmil](/molmil-images/mine/6z01) | DNA Topoisomerase | Descriptor: | CHLORIDE ION, DNA topoisomerase I | Authors: | Takahashi, T.S, Gadelle, D, Forterre, P, Mayer, C, Petrella, S. | Deposit date: | 2020-05-07 | Release date: | 2021-11-17 | Last modified: | 2023-05-31 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Topoisomerase I (TOP1) dynamics: conformational transition from open to closed states. Nat Commun, 13, 2022
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6Z03
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![BU of 6z03 by Molmil](/molmil-images/mine/6z03) | DNA Topoisomerase | Descriptor: | DNA topoisomerase I | Authors: | Takahashi, T.S, Gadelle, D, Forterre, P, Mayer, C, Petrella, S. | Deposit date: | 2020-05-07 | Release date: | 2021-11-17 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Topoisomerase I (TOP1) dynamics: conformational transition from open to closed states. Nat Commun, 13, 2022
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8APZ
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8AQ0
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2JQF
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![BU of 2jqf by Molmil](/molmil-images/mine/2jqf) | Full Length Leader Protease of Foot and Mouth Disease Virus C51A Mutant | Descriptor: | Genome polyprotein | Authors: | Cencic, R, Mayer, C, Juliano, M.A, Juliano, L, Konrat, R, Kontaxis, G, Skern, T. | Deposit date: | 2007-06-01 | Release date: | 2007-07-17 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Investigating the Substrate Specificity and Oligomerisation of the Leader Protease of Foot and Mouth Disease Virus using NMR J.Mol.Biol., 373, 2007
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2HKL
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![BU of 2hkl by Molmil](/molmil-images/mine/2hkl) | Crystal structure of Enterococcus faecium L,D-transpeptidase C442S mutant | Descriptor: | L,D-TRANSPEPTIDASE, SULFATE ION | Authors: | Delfosse, V, Hugonnet, J.-E, Magnet, S, Mainardi, J.-L, Arthur, M, Mayer, C. | Deposit date: | 2006-07-05 | Release date: | 2007-05-22 | Last modified: | 2023-08-30 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of Enterococcus faecium L,D-transpeptidase C442S mutant To be Published
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2JQG
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![BU of 2jqg by Molmil](/molmil-images/mine/2jqg) | Leader Protease | Descriptor: | Genome polyprotein | Authors: | Cencic, R, Mayer, C, Juliano, M.A, Juliano, L, Konrat, R, Kontaxis, G, Skern, T. | Deposit date: | 2007-06-01 | Release date: | 2007-07-24 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Investigating the Substrate Specificity and Oligomerisation of the Leader Protease of Foot and Mouth Disease Virus using NMR J.Mol.Biol., 373, 2007
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6GAU
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![BU of 6gau by Molmil](/molmil-images/mine/6gau) | Extremely 'open' clamp structure of DNA gyrase: role of the Corynebacteriales GyrB specific insert | Descriptor: | DNA gyrase subunit B,DNA gyrase subunit A, MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | Authors: | Petrella, S, Capton, E, Alzari, P.M, Aubry, A, Mayer, C. | Deposit date: | 2018-04-12 | Release date: | 2019-02-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | Overall Structures of Mycobacterium tuberculosis DNA Gyrase Reveal the Role of a Corynebacteriales GyrB-Specific Insert in ATPase Activity. Structure, 27, 2019
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6GAV
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![BU of 6gav by Molmil](/molmil-images/mine/6gav) | Extremely 'open' clamp structure of DNA gyrase: role of the Corynebacteriales GyrB specific insert | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, DNA gyrase subunit B,DNA gyrase subunit A | Authors: | Petrella, S, Capton, E, Alzari, P.M, Aubry, A, MAyer, C. | Deposit date: | 2018-04-12 | Release date: | 2019-02-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Overall Structures of Mycobacterium tuberculosis DNA Gyrase Reveal the Role of a Corynebacteriales GyrB-Specific Insert in ATPase Activity. Structure, 27, 2019
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2MZ8
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![BU of 2mz8 by Molmil](/molmil-images/mine/2mz8) | Solution NMR structure of Salmonella Typhimurium transcriptional regulator protein Crl | Descriptor: | Sigma factor-binding protein Crl | Authors: | Cavaliere, P, Levi-Acobas, F, Monteil, V, Bellalou, J, Mayer, C, Norel, F, Sizun, C. | Deposit date: | 2015-02-07 | Release date: | 2015-12-23 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Binding interface between the Salmonella sigma (S)/RpoS subunit of RNA polymerase and Crl: hints from bacterial species lacking crl. Sci Rep, 5, 2015
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6TTY
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![BU of 6tty by Molmil](/molmil-images/mine/6tty) | Structure of ClpP from Staphylococcus aureus (apo, closed state) | Descriptor: | ATP-dependent Clp protease proteolytic subunit | Authors: | Malik, I.T, Pereira, R, Vielberg, M.-T, Mayer, C, Straetener, J, Thomy, D, Famulla, K, Castro, H.C, Sass, P, Groll, M, Broetz-Oesterheldt, H. | Deposit date: | 2019-12-30 | Release date: | 2020-03-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Functional Characterisation of ClpP Mutations Conferring Resistance to Acyldepsipeptide Antibiotics in Firmicutes. Chembiochem, 21, 2020
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6TTZ
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![BU of 6ttz by Molmil](/molmil-images/mine/6ttz) | Structure of the ClpP:ADEP4-complex from Staphylococcus aureus (open state) | Descriptor: | ATP-dependent Clp protease proteolytic subunit, N-[(2S)-3-(3,5-difluorophenyl)-1-[[(3S,9S,13S,15R,19S,22S)-15,19-dimethyl-2,8,12,18,21-pentaoxo-11-oxa-1,7,17,20-tetrazatetracyclo[20.4.0.03,7.013,17]hexacosan-9-yl]amino]-1-oxopropan-2-yl]heptanamide | Authors: | Malik, I.T, Pereira, R, Vielberg, M.-T, Mayer, C, Straetener, J, Thomy, D, Famulla, K, Castro, H.C, Sass, P, Groll, M, Broetz-Oesterheldt, H. | Deposit date: | 2019-12-30 | Release date: | 2020-03-25 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Functional Characterisation of ClpP Mutations Conferring Resistance to Acyldepsipeptide Antibiotics in Firmicutes. Chembiochem, 21, 2020
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