3DDT
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7ESR
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6YP6
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8BVO
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8BXR
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8BW6
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![BU of 8bw6 by Molmil](/molmil-images/mine/8bw6) | Titin FnIII-domain I110 (I/A6) from the MIR region | Descriptor: | 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Mayans, O, Fleming, J.R. | Deposit date: | 2022-12-06 | Release date: | 2023-02-15 | Last modified: | 2023-03-08 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Immunological and Structural Characterization of Titin Main Immunogenic Region; I110 Domain Is the Target of Titin Antibodies in Myasthenia Gravis. Biomedicines, 11, 2023
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1O17
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6FWX
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![BU of 6fwx by Molmil](/molmil-images/mine/6fwx) | Chimeric titin Z1Z2-Z1Z2 tandem (Z1212) functionalized with a GRGDS exogenous peptide from fibronectin | Descriptor: | 1,2-ETHANEDIOL, Titin,Titin,Titin | Authors: | Mayans, O, Fleming, J, Hill, C. | Deposit date: | 2018-03-07 | Release date: | 2019-03-27 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | Self-Assembling Proteins as High-Performance Substrates for Embryonic Stem Cell Self-Renewal. Adv. Mater. Weinheim, 31, 2019
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1IDK
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![BU of 1idk by Molmil](/molmil-images/mine/1idk) | PECTIN LYASE A | Descriptor: | PECTIN LYASE A | Authors: | Mayans, O, Scott, M, Connerton, I, Gravesen, T, Benen, J, Visser, J, Pickersgill, R, Jenkins, J. | Deposit date: | 1996-10-04 | Release date: | 1997-10-15 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Two crystal structures of pectin lyase A from Aspergillus reveal a pH driven conformational change and striking divergence in the substrate-binding clefts of pectin and pectate lyases. Structure, 5, 1997
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1IDJ
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![BU of 1idj by Molmil](/molmil-images/mine/1idj) | PECTIN LYASE A | Descriptor: | PECTIN LYASE A | Authors: | Mayans, O, Scott, M, Connerton, I, Gravesen, T, Benen, J, Visser, J, Pickersgill, R, Jenkins, J. | Deposit date: | 1996-10-04 | Release date: | 1997-10-15 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Two crystal structures of pectin lyase A from Aspergillus reveal a pH driven conformational change and striking divergence in the substrate-binding clefts of pectin and pectate lyases. Structure, 5, 1997
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4GSN
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1GXB
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![BU of 1gxb by Molmil](/molmil-images/mine/1gxb) | ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE IN COMPLEX WITH PYROPHOSPHATE AND MAGNESIUM | Descriptor: | ANTHRANILATE PHOSPHORIBOSYLTRANSFERASE, MAGNESIUM ION, PYROPHOSPHATE 2- | Authors: | Mayans, O, Ivens, A, Nissen, L.J, Kirschner, K, Wilmanns, M. | Deposit date: | 2002-04-02 | Release date: | 2003-04-03 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structural Analysis of Two Enzymes Catalysing Reverse Metabolic Reactions Implies Common Ancestry Embo J., 21, 2002
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1G1C
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![BU of 1g1c by Molmil](/molmil-images/mine/1g1c) | I1 DOMAIN FROM TITIN | Descriptor: | IMMUNOGLOBULIN-LIKE DOMAIN I1 FROM TITIN | Authors: | Mayans, O, Wuerges, J, Gautel, M, Wilmanns, M. | Deposit date: | 2000-10-11 | Release date: | 2001-10-12 | Last modified: | 2019-12-11 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structural evidence for a possible role of reversible disulphide bridge formation in the elasticity of the muscle protein titin. Structure, 9, 2001
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4M3L
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![BU of 4m3l by Molmil](/molmil-images/mine/4m3l) | Crystal Structure of the coiled coil domain of MuRF1 | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, E3 ubiquitin-protein ligase TRIM63, ... | Authors: | Mayans, O, Franke, B. | Deposit date: | 2013-08-06 | Release date: | 2014-03-26 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Molecular basis for the fold organization and sarcomeric targeting of the muscle atrogin MuRF1. Open Biol, 4, 2014
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2RIK
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![BU of 2rik by Molmil](/molmil-images/mine/2rik) | I-band fragment I67-I69 from titin | Descriptor: | Titin | Authors: | Marino, M, von Castelmur, E, Labeit, D, Labeit, S, Mayans, O. | Deposit date: | 2007-10-11 | Release date: | 2008-01-22 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A regular pattern of Ig super-motifs defines segmental flexibility as the elastic mechanism of the titin chain Proc.Natl.Acad.Sci.Usa, 105, 2008
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7NIP
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8OSP
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7OI1
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1MXG
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![BU of 1mxg by Molmil](/molmil-images/mine/1mxg) | Crystal Structure of a (Ca,Zn)-dependent alpha-amylase from the hyperthermophilic archaeon Pyrococcus woesei in complex with acarbose | Descriptor: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-{2-[2-2-(METHOXY-ETHOXY)-ETHOXY]-ETHOXY}-ETHANOL, 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ... | Authors: | Linden, A, Mayans, O, Meyer-Klaucke, W, Antranikian, G, Wilmanns, M. | Deposit date: | 2002-10-02 | Release date: | 2003-06-10 | Last modified: | 2020-09-09 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Differential Regulation of a Hyperthermophilic alpha-Amylase with a Novel (Ca,Zn) Two-metal Center by Zinc J.Biol.Chem., 278, 2003
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1MXD
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![BU of 1mxd by Molmil](/molmil-images/mine/1mxd) | Structure of a (Ca,Zn)-dependent alpha-amylase from the hyperthermophilic archaeon Pyrococcus woesei | Descriptor: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, ACETATE ION, CALCIUM ION, ... | Authors: | Linden, A, Mayans, O, Meyer-Klaucke, W, Antranikian, G, Wilmanns, M. | Deposit date: | 2002-10-02 | Release date: | 2003-06-10 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Differential Regulation of a Hyperthermophilic alpha-Amylase with a Novel (Ca,Zn) Two-metal Center by Zinc J.Biol.Chem., 278, 2003
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1MWO
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![BU of 1mwo by Molmil](/molmil-images/mine/1mwo) | Crystal Structure Analysis of the Hyperthermostable Pyrocoocus woesei alpha-amylase | Descriptor: | CALCIUM ION, ZINC ION, alpha amylase | Authors: | Linden, A, Mayans, O, Meyer-Klaucke, W, Antranikian, G, Wilmanns, M. | Deposit date: | 2002-09-30 | Release date: | 2003-06-10 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Differential Regulation of a Hyperthermophilic alpha-Amylase with a Novel (Ca,Zn) Two-metal Center by Zinc J.Biol.Chem., 278, 2003
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7AHS
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![BU of 7ahs by Molmil](/molmil-images/mine/7ahs) | titin-N2A Ig81-Ig83 | Descriptor: | 1,2-ETHANEDIOL, GLYCEROL, Isoform 5 of Titin, ... | Authors: | Fleming, J.R, Mayans, O. | Deposit date: | 2020-09-25 | Release date: | 2021-03-24 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | The N2A region of titin has a unique structural configuration. J.Gen.Physiol., 153, 2021
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3GBR
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![BU of 3gbr by Molmil](/molmil-images/mine/3gbr) | Anthranilate phosphoribosyl-transferase (TRPD) double mutant D83G F149S from S. solfataricus | Descriptor: | 1-O-pyrophosphono-5-O-phosphono-alpha-D-ribofuranose, Anthranilate phosphoribosyltransferase, DI(HYDROXYETHYL)ETHER, ... | Authors: | Bruning, M, Schlee, S, Deuss, M, Ivens, A, Mayans, O, Sterner, R. | Deposit date: | 2009-02-20 | Release date: | 2009-12-15 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Activation of anthranilate phosphoribosyltransferase from Sulfolobus solfataricus by removal of magnesium inhibition and acceleration of product release Biochemistry, 48, 2009
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3B43
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![BU of 3b43 by Molmil](/molmil-images/mine/3b43) | I-band fragment I65-I70 from titin | Descriptor: | Titin | Authors: | von Castelmur, E, Marino, M, Labeit, D, Labeit, S, Mayans, O. | Deposit date: | 2007-10-23 | Release date: | 2008-01-22 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (3.3 Å) | Cite: | A regular pattern of Ig super-motifs defines segmental flexibility as the elastic mechanism of the titin chain Proc.Natl.Acad.Sci.Usa, 105, 2008
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4YRU
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![BU of 4yru by Molmil](/molmil-images/mine/4yru) | Crystal structure of C-terminally truncated Neuronal Calcium Sensor (NCS-1) from Rattus norvegicus | Descriptor: | CALCIUM ION, Neuronal calcium sensor 1 | Authors: | Pandalaneni, S, Karrupiah, V, Mayans, O, Derrick, J.P, Lian, L.Y. | Deposit date: | 2015-03-15 | Release date: | 2015-04-01 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Neuronal Calcium Sensor-1 Binds the D2 Dopamine Receptor and G-protein-coupled Receptor Kinase 1 (GRK1) Peptides Using Different Modes of Interactions. J.Biol.Chem., 290, 2015
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