3V83
 
 | | The 2.1 angstrom crystal structure of diferric human transferrin | | 分子名称: | BICARBONATE ION, FE (III) ION, HEXAETHYLENE GLYCOL, ... | | 著者 | Noinaj, N, Steere, A, Mason, A.B, Buchanan, S.K. | | 登録日 | 2011-12-22 | | 公開日 | 2012-02-15 | | 最終更新日 | 2012-04-18 | | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | | 主引用文献 | Structural basis for iron piracy by pathogenic Neisseria.
Nature, 483, 2012
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3FGS
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1RYO
 | | Human serum transferrin, N-lobe bound with oxalate | | 分子名称: | FE (III) ION, OXALATE ION, Serotransferrin | | 著者 | Halbrooks, P.J, Mason, A.B, Adams, T.E, Briggs, S.K, Everse, S.J. | | 登録日 | 2003-12-22 | | 公開日 | 2004-05-11 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.2 Å) | | 主引用文献 | The oxalate effect on release of iron from human serum transferrin explained.
J.Mol.Biol., 339, 2004
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3MC2
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2O84
 | | Crystal structure of K206E mutant of N-lobe human transferrin | | 分子名称: | CARBONATE ION, FE (III) ION, POTASSIUM ION, ... | | 著者 | Baker, H.M, Nurizzo, D, Mason, A.B, Baker, E.N. | | 登録日 | 2006-12-12 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Structures of two mutants that probe the role in iron release of the dilysine pair in the N-lobe of human transferrin.
Acta Crystallogr.,Sect.D, 63, 2007
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2O7U
 | | Crystal structure of K206E/K296E mutant of the N-terminal half molecule of human transferrin | | 分子名称: | CARBONATE ION, FE (III) ION, Serotransferrin | | 著者 | Baker, H.M, Nurizzo, D, Mason, A.B, Baker, E.N. | | 登録日 | 2006-12-11 | | 公開日 | 2007-01-23 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | Structures of two mutants that probe the role in iron release of the dilysine pair in the N-lobe of human transferrin.
Acta Crystallogr.,Sect.D, 63, 2007
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1JQF
 | | Human Transferrin N-Lobe Mutant H249Q | | 分子名称: | CARBONATE ION, FE (III) ION, POTASSIUM ION, ... | | 著者 | Baker, H.M, Mason, A.B, He, Q.-Y, MacGillivray, R.T.A, Baker, E.N. | | 登録日 | 2001-08-06 | | 公開日 | 2001-10-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Ligand variation in the transferrin family: the crystal structure of the H249Q mutant of the human transferrin N-lobe as a model for iron binding in insect transferrins.
Biochemistry, 40, 2001
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1N7W
 | | Crystal Structure of Human Serum Transferrin, N-Lobe L66W mutant | | 分子名称: | CARBONATE ION, FE (III) ION, Serotransferrin | | 著者 | Adams, T.E, Mason, A.B, He, Q.Y, Halbrooks, P.J, Briggs, S.K, Smith, V.C, MacGillivray, R.T, Everse, S.J. | | 登録日 | 2002-11-18 | | 公開日 | 2003-03-18 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | The Position of Arginine 124 Controls the Rate of Iron Release from the N-lobe of Human Serum Transferrin. A Structural Study
J.Biol.Chem., 278, 2003
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1N84
 | | HUMAN SERUM TRANSFERRIN, N-LOBE | | 分子名称: | CARBONATE ION, FE (III) ION, Serotransferrin | | 著者 | Adams, T.E, Mason, A.B, He, Q.Y, Halbrooks, P.J, Briggs, S.K, Smith, V.C, Macgillivray, R.T, Everse, S.J. | | 登録日 | 2002-11-19 | | 公開日 | 2003-03-18 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | THE POSITION OF ARGININE 124 CONTROLS THE RATE OF IRON RELEASE FROM THE N-LOBE OF HUMAN SERUM TRANSFERRIN. A STRUCTURAL STUDY
J.Biol.Chem., 278, 2003
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1N7X
 | | HUMAN SERUM TRANSFERRIN, N-LOBE Y45E MUTANT | | 分子名称: | CARBONATE ION, FE (III) ION, Serotransferrin | | 著者 | Adams, T.E, Mason, A.B, He, Q.Y, Halbrooks, P.J, Briggs, S.K, Smith, V.C, Macgillivray, R.T, Everse, S.J. | | 登録日 | 2002-11-18 | | 公開日 | 2003-03-18 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | THE POSITION OF ARGININE 124 CONTROLS THE RATE OF IRON RELEASE FROM THE N-LOBE OF HUMAN SERUM TRANSFERRIN. A STRUCTURAL STUDY
J.Biol.Chem., 278, 2003
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1OQG
 | | Crystal structure of the D63E mutant of the N-lobe human transferrin | | 分子名称: | CARBONATE ION, FE (III) ION, Serotransferrin | | 著者 | Baker, H.M, He, Q.-Y, Brigg, S.K, Mason, A.B, Baker, E.N. | | 登録日 | 2003-03-09 | | 公開日 | 2003-03-18 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Structural and functional consequences of binding site mutations in transferrin: crystal structures of the Asp63Glu and Arg124Ala mutants of the N-lobe of human transferrin
Biochemistry, 42, 2003
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1OQH
 | | Crystal Structure of the R124A mutant of the N-lobe human transferrin | | 分子名称: | CARBONATE ION, FE (III) ION, POTASSIUM ION, ... | | 著者 | Baker, H.M, He, Q.-Y, Brigg, S.K, Mason, A.B, N Baker, E. | | 登録日 | 2003-03-10 | | 公開日 | 2003-03-18 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Structural and functional consequences of binding site mutations in transferrin: crystal structures of the Asp63Glu and Arg124Ala mutants of the N-lobe of human transferrin
Biochemistry, 42, 2003
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1BTJ
 | | HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE, APO FORM, CRYSTAL FORM 2 | | 分子名称: | PROTEIN (SERUM TRANSFERRIN) | | 著者 | Jeffrey, P.D, Bewley, M.C, Macgillivray, R.T.A, Mason, A.B, Woodworth, R.C, Baker, E.N. | | 登録日 | 1998-09-01 | | 公開日 | 1999-01-13 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | | 主引用文献 | Ligand-induced conformational change in transferrins: crystal structure of the open form of the N-terminal half-molecule of human transferrin.
Biochemistry, 37, 1998
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1BP5
 | | HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE, APO FORM | | 分子名称: | PROTEIN (SERUM TRANSFERRIN) | | 著者 | Jeffrey, P.D, Bewley, M.C, Macgillivray, R.T.A, Mason, A.B, Woodworth, R.C, Baker, E.N. | | 登録日 | 1998-08-12 | | 公開日 | 1999-01-13 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Ligand-induced conformational change in transferrins: crystal structure of the open form of the N-terminal half-molecule of human transferrin.
Biochemistry, 37, 1998
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1A8F
 | | HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE | | 分子名称: | CARBONATE ION, FE (III) ION, SERUM TRANSFERRIN | | 著者 | Macgillivray, R.T.A, Moore, S.A, Chen, J, Anderson, B.F, Baker, H, Luo, Y, Bewley, M, Smith, C.A, Murphy, M.E.P, Wang, Y, Mason, A.B, Woodworth, R.C, Brayer, G.D, Baker, E.N. | | 登録日 | 1998-03-25 | | 公開日 | 1998-06-17 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Two high-resolution crystal structures of the recombinant N-lobe of human transferrin reveal a structural change implicated in iron release.
Biochemistry, 37, 1998
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1A8E
 | | HUMAN SERUM TRANSFERRIN, RECOMBINANT N-TERMINAL LOBE | | 分子名称: | CARBONATE ION, FE (III) ION, SERUM TRANSFERRIN | | 著者 | Macgillivray, R.T.A, Moore, S.A, Chen, J, Anderson, B.F, Baker, H, Luo, Y, Bewley, M, Smith, C.A, Murphy, M.E.P, Wang, Y, Mason, A.B, Woodworth, R.C, Brayer, G.D, Baker, E.N. | | 登録日 | 1998-03-24 | | 公開日 | 1998-06-17 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | | 主引用文献 | Two high-resolution crystal structures of the recombinant N-lobe of human transferrin reveal a structural change implicated in iron release.
Biochemistry, 37, 1998
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1B3E
 | | HUMAN SERUM TRANSFERRIN, N-TERMINAL LOBE, EXPRESSED IN PICHIA PASTORIS | | 分子名称: | CARBONATE ION, FE (III) ION, PROTEIN (SERUM TRANSFERRIN) | | 著者 | Bewley, M.C, Tam, B.M, Grewal, J, He, S, Shewry, S, Murphy, M.E.P, Mason, A.B, Woodworth, R.C, Baker, E.N, Macgillivray, R.T.A. | | 登録日 | 1998-12-09 | | 公開日 | 1999-03-26 | | 最終更新日 | 2023-08-09 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | X-ray crystallography and mass spectroscopy reveal that the N-lobe of human transferrin expressed in Pichia pastoris is folded correctly but is glycosylated on serine-32.
Biochemistry, 38, 1999
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1DTG
 | | HUMAN TRANSFERRIN N-LOBE MUTANT H249E | | 分子名称: | CARBONATE ION, FE (III) ION, TRANSFERRIN | | 著者 | MacGillivray, R.T, Bewley, M.C, Smith, C.A, He, Q.Y, Mason, A.B. | | 登録日 | 2000-01-12 | | 公開日 | 2000-01-21 | | 最終更新日 | 2021-11-03 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Mutation of the iron ligand His 249 to Glu in the N-lobe of human transferrin abolishes the dilysine "trigger" but does not significantly affect iron release.
Biochemistry, 39, 2000
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3SKP
 | | The structure of apo-human transferrin C-lobe with bound sulfate ions | | 分子名称: | SULFATE ION, Serotransferrin | | 著者 | Noinaj, N, Steere, A.N, Mason, A.B, Buchanan, S.K. | | 登録日 | 2011-06-22 | | 公開日 | 2012-02-15 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structural basis for iron piracy by pathogenic Neisseria.
Nature, 483, 2012
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3S9L
 | | Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, cryocooled 2 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CARBONATE ION, ... | | 著者 | Eckenroth, B.E, Steere, A.N, Mason, A.B, Everse, S.J. | | 登録日 | 2011-06-01 | | 公開日 | 2011-08-10 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | | 主引用文献 | How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3S9M
 | | Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, cryocooled 1 | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CARBONATE ION, ... | | 著者 | Eckenroth, B.E, Steere, A.N, Mason, A.B, Everse, S.J. | | 登録日 | 2011-06-01 | | 公開日 | 2011-08-10 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.32 Å) | | 主引用文献 | How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH.
Proc.Natl.Acad.Sci.USA, 108, 2011
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3S9N
 | | Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, room temperature | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CARBONATE ION, ... | | 著者 | Eckenroth, B.E, Steere, A.N, Mason, A.B, Everse, S.J. | | 登録日 | 2011-06-01 | | 公開日 | 2011-08-10 | | 最終更新日 | 2020-07-29 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH.
Proc.Natl.Acad.Sci.USA, 108, 2011
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