8JZ0
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8JZ1
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1OQH
| Crystal Structure of the R124A mutant of the N-lobe human transferrin | 分子名称: | CARBONATE ION, FE (III) ION, POTASSIUM ION, ... | 著者 | Baker, H.M, He, Q.-Y, Brigg, S.K, Mason, A.B, N Baker, E. | 登録日 | 2003-03-10 | 公開日 | 2003-03-18 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural and functional consequences of binding site mutations in transferrin: crystal structures of the Asp63Glu and Arg124Ala mutants of the N-lobe of human transferrin Biochemistry, 42, 2003
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3VVI
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3WTN
| Crystal Structure of Lymnaea stagnalis Acetylcholine Binding Protein Complexed with Desnitro-imidacloprid | 分子名称: | (2Z)-1-[(6-chloropyridin-3-yl)methyl]imidazolidin-2-imine, Acetylcholine-binding protein, CADMIUM ION, ... | 著者 | Okajima, T, Ihara, M, Yamashita, A, Oda, T, Matsuda, K. | 登録日 | 2014-04-11 | 公開日 | 2015-02-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.09 Å) | 主引用文献 | Studies on an acetylcholine binding protein identify a basic residue in loop G on the beta 1 strand as a new structural determinant of neonicotinoid actions Mol.Pharmacol., 86, 2014
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1URW
| CDK2 IN COMPLEX WITH AN IMIDAZO[1,2-b]PYRIDAZINE | 分子名称: | 2-[4-(N-(3-DIMETHYLAMINOPROPYL)SULPHAMOYL)ANILINO]-, CELL DIVISION PROTEIN KINASE 2 | 著者 | Byth, K.F, Cooper, N, Culshaw, J.D, Heaton, D.W, Oakes, S.E, Minshull, C.A, Norman, R.A, Pauptit, R.A, Tucker, J.A, Breed, J, Pannifer, A, Rowsell, S, Stanway, J.J, Valentine, A.L, Thomas, A.P. | 登録日 | 2003-11-11 | 公開日 | 2004-04-23 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Imidazo[1,2-B]Pyridazines: A Potent and Selective Class of Cyclin-Dependent Kinase Inhibitors Bioorg.Med.Chem.Lett., 14, 2004
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3S9M
| Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, cryocooled 1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CARBONATE ION, ... | 著者 | Eckenroth, B.E, Steere, A.N, Mason, A.B, Everse, S.J. | 登録日 | 2011-06-01 | 公開日 | 2011-08-10 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.32 Å) | 主引用文献 | How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH. Proc.Natl.Acad.Sci.USA, 108, 2011
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3ZI8
| Structure of the R17A mutant of the Ralstonia soleanacerum lectin at 1.5 Angstrom in complex with L-fucose | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, MAGNESIUM ION, PUTATIVE FUCOSE-BINDING LECTIN PROTEIN, ... | 著者 | Arnaud, J, Audfray, A, Claudinon, J, Trondle, K, Trosvalet, M, Thomas, A, Varrot, A, Romer, W, Imberty, A. | 登録日 | 2013-01-07 | 公開日 | 2013-07-31 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Reduction of Lectin Valency Drastically Changes Glycolipid Dynamics in Membranes, But not Surface Avidity. Acs Chem.Biol., 8, 2013
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3S9N
| Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, room temperature | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CARBONATE ION, ... | 著者 | Eckenroth, B.E, Steere, A.N, Mason, A.B, Everse, S.J. | 登録日 | 2011-06-01 | 公開日 | 2011-08-10 | 最終更新日 | 2024-10-09 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH. Proc.Natl.Acad.Sci.USA, 108, 2011
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3S9L
| Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, cryocooled 2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CARBONATE ION, ... | 著者 | Eckenroth, B.E, Steere, A.N, Mason, A.B, Everse, S.J. | 登録日 | 2011-06-01 | 公開日 | 2011-08-10 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | 主引用文献 | How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH. Proc.Natl.Acad.Sci.USA, 108, 2011
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2CCT
| HUMAN HSP90 WITH 5-(5-CHLORO-2,4-DIHYDROXY-PHENYL)-4-PIPERAZIN-1-YL- 2H-PYRAZOLE-3-CARBOXYLIC ACID ETHYLAMIDE | 分子名称: | 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-PIPERAZIN-1-YL-1H-PYRAZOLE-3-CARBOXAMIDE, HEAT SHOCK PROTEIN HSP-90 ALPHA | 著者 | Barril, X, Beswick, M.C, Collier, A, Drysdale, M.J, Dymock, B.W, Fink, A, Grant, K, Howes, R, Jordan, A.M, Massey, A, Surgenor, A, Wayne, J, Workman, P, Wright, L. | 登録日 | 2006-01-18 | 公開日 | 2006-02-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | 4-Amino derivatives of the Hsp90 inhibitor CCT018159. Bioorg. Med. Chem. Lett., 16, 2006
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2BZ5
| Structure-based Discovery of a New Class of Hsp90 Inhibitors | 分子名称: | 2,5-DICHLORO-N-[4-HYDROXY-3-(2-HYDROXY-1-NAPHTHYL)PHENYL]BENZENESULFONAMIDE, HEAT SHOCK PROTEIN HSP90-ALPHA | 著者 | Barril, X, Brough, P, Drysdale, M, Hubbard, R.E, Massey, A, Surgenor, A, Wright, L. | 登録日 | 2005-08-11 | 公開日 | 2005-10-12 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure-Based Discovery of a New Class of Hsp90 Inhibitors. Bioorg.Med.Chem.Lett., 15, 2005
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2CCS
| HUMAN HSP90 WITH 4-CHLORO-6-(4-PIPERAZIN-1-YL-1H-PYRAZOL-3-YL)- BENZENE-1,2-DIOL | 分子名称: | 4-CHLORO-6-(4-PIPERAZIN-1-YL-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL, HEAT SHOCK PROTEIN HSP-90 ALPHA | 著者 | Barril, X, Beswick, M.C, Collier, A, Drysdale, M.J, Dymock, B.W, Fink, A, Grant, K, Howes, R, Jordan, A.M, Massey, A, Surgenor, A, Wayne, J, Workman, P, Wright, L. | 登録日 | 2006-01-18 | 公開日 | 2006-02-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | 主引用文献 | 4-Amino derivatives of the Hsp90 inhibitor CCT018159. Bioorg. Med. Chem. Lett., 16, 2006
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3WTM
| Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein Q55R Mutant Complexed with Nitromethylene Analogue of Imidacloprid | 分子名称: | 2-chloro-5-{[(2E)-2-(nitromethylidene)imidazolidin-1-yl]methyl}pyridine, Acetylcholine-binding protein | 著者 | Okajima, T, Ihara, M, Yamashita, A, Oda, T, Matsuda, K. | 登録日 | 2014-04-11 | 公開日 | 2015-02-04 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Studies on an acetylcholine binding protein identify a basic residue in loop G on the beta 1 strand as a new structural determinant of neonicotinoid actions Mol.Pharmacol., 86, 2014
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1TT6
| The orthorhombic crystal structure of transthyretin in complex with diethylstilbestrol | 分子名称: | DIETHYLSTILBESTROL, GLYCEROL, SULFATE ION, ... | 著者 | Morais-de-Sa, E.M, Pereira, P.J.B, Saraiva, M.J, Damas, A.M. | 登録日 | 2004-06-22 | 公開日 | 2004-10-12 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The crystal structure of transthyretin in complex with diethylstilbestrol: a promising template for the design of amyloid inhibitors J.Biol.Chem., 279, 2004
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2CJI
| Crystal structure of a Human Factor Xa inhibitor complex | 分子名称: | 6-CHLORO-N-{(3S)-1-[(1S)-1-METHYL-2-(4-MORPHOLINYL)-2-OXO ETHYL]-2-OXO-3-PYRROLIDINYL}-2-NAPHTHALENESULFONAMIDE, ACTIVATED FACTOR XA HEAVY CHAIN, CALCIUM ION, ... | 著者 | Watson, N.S, Campbell, M, Chan, C, Convery, M.A, Hamblin, J.N, Kelly, H.A, King, N.P, Mason, A.M, Mitchell, C, Patel, V.K, Senger, S, Shah, G.P, Weston, H.E, Whitworth, C, Young, R.J. | 登録日 | 2006-04-03 | 公開日 | 2006-05-17 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Design and Synthesis of Orally Active Pyrrolidin-2-One-Based Factor Xa Inhibitors Bioorg.Med.Chem.Lett., 16, 2006
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2B15
| The crystal structure of 2,4-dinitrophenol in complex with human transthyretin | 分子名称: | 2,4-DINITROPHENOL, SULFATE ION, Transthyretin | 著者 | Morais-de-Sa, E, Neto-Silva, R.M, Pereira, P.J, Saraiva, M.J, Damas, A.M. | 登録日 | 2005-09-15 | 公開日 | 2006-07-18 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | The binding of 2,4-dinitrophenol to wild-type and amyloidogenic transthyretin ACTA CRYSTALLOGR.,SECT.D, 62, 2006
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3WTL
| Crystal Structure of Lymnaea stagnalis Acetylcholine Binding Protein Complexed with Nitromethylene Analogue of Imidacloprid | 分子名称: | 2-chloro-5-{[(2E)-2-(nitromethylidene)imidazolidin-1-yl]methyl}pyridine, Acetylcholine-binding protein | 著者 | Okajima, T, Ihara, M, Yamashita, A, Oda, T, Matsuda, K. | 登録日 | 2014-04-11 | 公開日 | 2015-02-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Studies on an acetylcholine binding protein identify a basic residue in loop G on the beta 1 strand as a new structural determinant of neonicotinoid actions Mol.Pharmacol., 86, 2014
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2CCU
| HUMAN HSP90 WITH 4-CHLORO-6-(4-(4-(4-METHANESULPHONYL-BENZYL)- PIERAZIN-1-YL)-1H-PYRAZOL-3-YL)-BENZENE-1,3-DIOL | 分子名称: | 4-CHLORO-6-(4-{4-[4-(METHYLSULFONYL)BENZYL]PIPERAZIN-1-YL}-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL, HEAT SHOCK PROTEIN HSP-90 ALPHA | 著者 | Barril, X, Beswick, M.C, Collier, A, Drysdale, M.J, Dymock, B.W, Fink, A, Grant, K, Howes, R, Jordan, A.M, Massey, A, Surgenor, A, Wayne, J, Workman, P, Wright, L. | 登録日 | 2006-01-18 | 公開日 | 2006-02-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | 4-Amino derivatives of the Hsp90 inhibitor CCT018159. Bioorg. Med. Chem. Lett., 16, 2006
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3WTJ
| Crystal Structure of Lymnaea stagnalis Acetylcholine Binding Protein Complexed with Thiacloprid | 分子名称: | Acetylcholine-binding protein, {(2Z)-3-[(6-chloropyridin-3-yl)methyl]-1,3-thiazolidin-2-ylidene}cyanamide | 著者 | Okajima, T, Ihara, M, Yamashita, A, Oda, T, Matsuda, K. | 登録日 | 2014-04-11 | 公開日 | 2015-02-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.24 Å) | 主引用文献 | Studies on an acetylcholine binding protein identify a basic residue in loop G on the beta 1 strand as a new structural determinant of neonicotinoid actions Mol.Pharmacol., 86, 2014
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1TWI
| Crystal structure of Diaminopimelate Decarboxylase from m. jannaschii in co-complex with L-lysine | 分子名称: | Diaminopimelate decarboxylase, LYSINE, MAGNESIUM ION, ... | 著者 | Rajashankar, K.R, Ray, S.S, Bonanno, J.B, Pinho, M.G, He, G, De Lencastre, H, Tomasz, A, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2004-07-01 | 公開日 | 2004-07-27 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Cocrystal structures of diaminopimelate decarboxylase: mechanism, evolution, and inhibition of an antibiotic resistance accessory factor Structure, 10, 2002
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1SOJ
| CATALYTIC DOMAIN OF HUMAN PHOSPHODIESTERASE 3B IN COMPLEX WITH IBMX | 分子名称: | 3-ISOBUTYL-1-METHYLXANTHINE, MAGNESIUM ION, cGMP-inhibited 3',5'-cyclic phosphodiesterase B | 著者 | Scapin, G, Patel, S.B, Chung, C, Varnerin, J.P, Edmondson, S.D, Mastracchio, A, Parmee, E.R, Becker, J.W, Singh, S.B, Van Der Ploeg, L.H, Tota, M.R. | 登録日 | 2004-03-15 | 公開日 | 2004-05-11 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Crystal Structure of Human Phosphodiesterase 3B: Atomic Basis for Substrate and Inhibitor Specificity Biochemistry, 43, 2004
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3WTO
| Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein Q55R Mutant Complexed with Desnitro-imidacloprid | 分子名称: | (2Z)-1-[(6-chloropyridin-3-yl)methyl]imidazolidin-2-imine, Acetylcholine-binding protein | 著者 | Okajima, T, Ihara, M, Yamashita, A, Oda, T, Matsuda, K. | 登録日 | 2014-04-11 | 公開日 | 2015-02-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Studies on an acetylcholine binding protein identify a basic residue in loop G on the beta 1 strand as a new structural determinant of neonicotinoid actions Mol.Pharmacol., 86, 2014
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3WTK
| Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein Q55R Mutant Complexed with Thiacloprid | 分子名称: | Acetylcholine-binding protein, {(2Z)-3-[(6-chloropyridin-3-yl)methyl]-1,3-thiazolidin-2-ylidene}cyanamide | 著者 | Okajima, T, Ihara, M, Yamashita, A, Oda, T, Matsuda, K. | 登録日 | 2014-04-11 | 公開日 | 2015-02-04 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.69 Å) | 主引用文献 | Studies on an acetylcholine binding protein identify a basic residue in loop G on the beta 1 strand as a new structural determinant of neonicotinoid actions Mol.Pharmacol., 86, 2014
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3WTI
| Crystal Structure of Lymnaea stagnalis Acetylcholine-Binding Protein Q55R Mutant Complexed with Clothianidin | 分子名称: | 1-[(2-chloro-1,3-thiazol-5-yl)methyl]-3-methyl-2-nitroguanidine, Acetylcholine-binding protein | 著者 | Okajima, T, Ihara, M, Yamashita, A, Oda, T, Matsuda, K. | 登録日 | 2014-04-11 | 公開日 | 2015-02-04 | 実験手法 | X-RAY DIFFRACTION (2.68 Å) | 主引用文献 | Studies on an acetylcholine binding protein identify a basic residue in loop G on the beta 1 strand as a new structural determinant of neonicotinoid actions Mol.Pharmacol., 86, 2014
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