3LDL
| Crystal structure of human GRP78 (70kDa heat shock protein 5 / BIP) ATPase domain in complex with ATP | 分子名称: | 78 kDa glucose-regulated protein, ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION | 著者 | Dokurno, P, Surgenor, A.E, Shaw, T, Macias, A.T, Massey, A.J, Williamson, D.S. | 登録日 | 2010-01-13 | 公開日 | 2011-01-26 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Adenosine-Derived Inhibitors of 78 kDa Glucose Regulated Protein (Grp78) ATPase: Insights into Isoform Selectivity. J.Med.Chem., 54, 2011
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1OQG
| Crystal structure of the D63E mutant of the N-lobe human transferrin | 分子名称: | CARBONATE ION, FE (III) ION, Serotransferrin | 著者 | Baker, H.M, He, Q.-Y, Brigg, S.K, Mason, A.B, Baker, E.N. | 登録日 | 2003-03-09 | 公開日 | 2003-03-18 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structural and functional consequences of binding site mutations in transferrin: crystal structures of the Asp63Glu and Arg124Ala mutants of the N-lobe of human transferrin Biochemistry, 42, 2003
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1OS0
| Thermolysin with an alpha-amino phosphinic inhibitor | 分子名称: | CALCIUM ION, DIMETHYL SULFOXIDE, N-{(2R)-3-[(S)-[(1R)-1-amino-2-phenylethyl](hydroxy)phosphoryl]-2-benzylpropanoyl}-L-phenylalanine, ... | 著者 | Selkti, M, Tomas, A, Prange, T. | 登録日 | 2003-03-18 | 公開日 | 2003-03-25 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Interactions of a new alpha-aminophosphinic derivative inside the active site of TLN (thermolysin): a model for zinc-metalloendopeptidase inhibition. Acta Crystallogr.,Sect.D, 59, 2003
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1N7X
| HUMAN SERUM TRANSFERRIN, N-LOBE Y45E MUTANT | 分子名称: | CARBONATE ION, FE (III) ION, Serotransferrin | 著者 | Adams, T.E, Mason, A.B, He, Q.Y, Halbrooks, P.J, Briggs, S.K, Smith, V.C, Macgillivray, R.T, Everse, S.J. | 登録日 | 2002-11-18 | 公開日 | 2003-03-18 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | THE POSITION OF ARGININE 124 CONTROLS THE RATE OF IRON RELEASE FROM THE N-LOBE OF HUMAN SERUM TRANSFERRIN. A STRUCTURAL STUDY J.Biol.Chem., 278, 2003
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1N7W
| Crystal Structure of Human Serum Transferrin, N-Lobe L66W mutant | 分子名称: | CARBONATE ION, FE (III) ION, Serotransferrin | 著者 | Adams, T.E, Mason, A.B, He, Q.Y, Halbrooks, P.J, Briggs, S.K, Smith, V.C, MacGillivray, R.T, Everse, S.J. | 登録日 | 2002-11-18 | 公開日 | 2003-03-18 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | The Position of Arginine 124 Controls the Rate of Iron Release from the N-lobe of Human Serum Transferrin. A Structural Study J.Biol.Chem., 278, 2003
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2J4I
| CRYSTAL STRUCTURE OF A HUMAN FACTOR XA INHIBITOR COMPLEX | 分子名称: | 1-PYRROLIDINEACETAMIDE, 3-[[(6-CHLORO-2-NAPHTHALENYL)SULFONYL]AMINO]-ALPHA-METHYL-N-(1-METHYLETHYL)-N-[2-[(METHYLSULFONYL)AMINO]ETHYL]-2-OXO-, (ALPHAS,3S)-, ... | 著者 | Young, R.J, Campbell, M, Borthwick, A.D, Brown, D, Chan, C, Convery, M.A, Crowe, M.C, Dayal, S, Diallo, H, Kelly, H.A, Paul King, N, Kleanthous, S, Kurtis, C.L, Mason, A.M, Mordaunt, J.E, Patel, C, Pateman, A.J, Senger, S, Shah, G.P, Smith, P.W, Watson, N.S, Weston, H.E, Zhou, P. | 登録日 | 2006-08-31 | 公開日 | 2006-09-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Structure- and Property-Based Design of Factor Xa Inhibitors: Pyrrolidin-2-Ones with Acyclic Alanyl Amides as P4 Motifs. Bioorg.Med.Chem.Lett., 16, 2006
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3S9L
| Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, cryocooled 2 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CARBONATE ION, ... | 著者 | Eckenroth, B.E, Steere, A.N, Mason, A.B, Everse, S.J. | 登録日 | 2011-06-01 | 公開日 | 2011-08-10 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.22 Å) | 主引用文献 | How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH. Proc.Natl.Acad.Sci.USA, 108, 2011
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1N2W
| Solution Structure of 8OG:G mismatch containing duplex | 分子名称: | 5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(8OG)P*GP*CP*G)-3' | 著者 | Thiviyanathan, V, Somasunderam, A.D, Hazra, T.K, Mitra, S, Gorenstein, D.G. | 登録日 | 2002-10-24 | 公開日 | 2002-11-13 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of a DNA Duplex Containing 8-Hydroxy-2'-Deoxyguanosine Opposite Deoxyguanosine J.Mol.Biol., 325, 2003
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1URW
| CDK2 IN COMPLEX WITH AN IMIDAZO[1,2-b]PYRIDAZINE | 分子名称: | 2-[4-(N-(3-DIMETHYLAMINOPROPYL)SULPHAMOYL)ANILINO]-, CELL DIVISION PROTEIN KINASE 2 | 著者 | Byth, K.F, Cooper, N, Culshaw, J.D, Heaton, D.W, Oakes, S.E, Minshull, C.A, Norman, R.A, Pauptit, R.A, Tucker, J.A, Breed, J, Pannifer, A, Rowsell, S, Stanway, J.J, Valentine, A.L, Thomas, A.P. | 登録日 | 2003-11-11 | 公開日 | 2004-04-23 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Imidazo[1,2-B]Pyridazines: A Potent and Selective Class of Cyclin-Dependent Kinase Inhibitors Bioorg.Med.Chem.Lett., 14, 2004
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1QF0
| THERMOLYSIN (E.C.3.4.24.27) COMPLEXED WITH (2-SULPHANYL-3-PHENYLPROPANOYL)-PHE-TYR. PARAMETERS FOR ZN-BIDENTATION OF MERCAPTOACYLDIPEPTIDES IN METALLOENDOPEPTIDASE | 分子名称: | (2-SULFANYL-3-PHENYLPROPANOYL)-PHE-TYR, CALCIUM ION, DIMETHYL SULFOXIDE, ... | 著者 | Gaucher, J.-F, Selkti, M, Tiraboschi, G, Prange, T, Roques, B.P, Tomas, A, Fournie-Zaluski, M.C. | 登録日 | 1999-04-06 | 公開日 | 1999-12-29 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Crystal structures of alpha-mercaptoacyldipeptides in the thermolysin active site: structural parameters for a Zn monodentation or bidentation in metalloendopeptidases. Biochemistry, 38, 1999
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3S9M
| Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, cryocooled 1 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CARBONATE ION, ... | 著者 | Eckenroth, B.E, Steere, A.N, Mason, A.B, Everse, S.J. | 登録日 | 2011-06-01 | 公開日 | 2011-08-10 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.32 Å) | 主引用文献 | How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH. Proc.Natl.Acad.Sci.USA, 108, 2011
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1N84
| HUMAN SERUM TRANSFERRIN, N-LOBE | 分子名称: | CARBONATE ION, FE (III) ION, Serotransferrin | 著者 | Adams, T.E, Mason, A.B, He, Q.Y, Halbrooks, P.J, Briggs, S.K, Smith, V.C, Macgillivray, R.T, Everse, S.J. | 登録日 | 2002-11-19 | 公開日 | 2003-03-18 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | 主引用文献 | THE POSITION OF ARGININE 124 CONTROLS THE RATE OF IRON RELEASE FROM THE N-LOBE OF HUMAN SERUM TRANSFERRIN. A STRUCTURAL STUDY J.Biol.Chem., 278, 2003
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3S9N
| Complex between transferrin receptor 1 and transferrin with iron in the N-Lobe, room temperature | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, CARBONATE ION, ... | 著者 | Eckenroth, B.E, Steere, A.N, Mason, A.B, Everse, S.J. | 登録日 | 2011-06-01 | 公開日 | 2011-08-10 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | How the binding of human transferrin primes the transferrin receptor potentiating iron release at endosomal pH. Proc.Natl.Acad.Sci.USA, 108, 2011
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1QF1
| THERMOLYSIN (E.C.3.4.24.27) COMPLEXED WITH (2-SULPHANYLHEPTANOYL)-PHE-ALA. PARAMETERS FOR ZN-BIDENTATION OF MERCAPTOACYLDIPEPTIDES IN METALLOENDOPEPTIDASE | 分子名称: | CALCIUM ION, DIMETHYL SULFOXIDE, PROTEIN (THERMOLYSIN), ... | 著者 | Gaucher, J.-F, Selkti, M, Tiraboschi, G, Prange, T, Roques, B.P, Tomas, A, Fournie-Zaluski, M.C. | 登録日 | 1999-04-06 | 公開日 | 1999-12-29 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structures of alpha-mercaptoacyldipeptides in the thermolysin active site: structural parameters for a Zn monodentation or bidentation in metalloendopeptidases. Biochemistry, 38, 1999
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1OQH
| Crystal Structure of the R124A mutant of the N-lobe human transferrin | 分子名称: | CARBONATE ION, FE (III) ION, POTASSIUM ION, ... | 著者 | Baker, H.M, He, Q.-Y, Brigg, S.K, Mason, A.B, N Baker, E. | 登録日 | 2003-03-10 | 公開日 | 2003-03-18 | 最終更新日 | 2023-08-16 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structural and functional consequences of binding site mutations in transferrin: crystal structures of the Asp63Glu and Arg124Ala mutants of the N-lobe of human transferrin Biochemistry, 42, 2003
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2IZ7
| structure of Moco Carrier Protein from Chlamydomonas reinhardtii | 分子名称: | MOCO CARRIER PROTEIN | 著者 | Fischer, K, Llamas, A, Tejada-Jimenez, M, Schrader, N, Kuper, J, Mendel, R.R, Fernandez, E, Schwarz, G. | 登録日 | 2006-07-25 | 公開日 | 2006-07-27 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | 主引用文献 | Function and Structure of the Molybdenum Cofactor Carrier Protein from Chlamydomonas Reinhardtii. J.Biol.Chem., 281, 2006
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2IZ6
| Structure of the Chlamydomonas rheinhardtii Moco Carrier Protein | 分子名称: | MOLYBDENUM COFACTOR CARRIER PROTEIN | 著者 | Fischer, K, Llamas, A, Tejada-Jimenez, M, Schrader, N, Kuper, J, Mendel, R.R, Fernandez, E, Schwarz, G. | 登録日 | 2006-07-25 | 公開日 | 2006-07-26 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Function and Structure of the Molybdenum Cofactor Carrier Protein from Chlamydomonas Reinhardtii. J.Biol.Chem., 281, 2006
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2IZ5
| FUNCTION AND STRUCTURE OF THE MOLYBDENUM COFACTOR CARRIER PROTEIN MCP FROM CHLAMYDOMONAS REINHARDTII | 分子名称: | MOCO CARRIER PROTEIN | 著者 | Fischer, K, Llamas, A, Tejada-Jimenez, M, Schrader, N, Kuper, J, Mendel, R.R, Fernandez, E, Schwarz, G. | 登録日 | 2006-07-25 | 公開日 | 2006-07-26 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.29 Å) | 主引用文献 | Function and Structure of the Molybdenum Cofactor Carrier Protein from Chlamydomonas Reinhardtii. J.Biol.Chem., 281, 2006
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2J4W
| Structure of a Plasmodium vivax apical membrane antigen 1-Fab F8.12.19 complex | 分子名称: | APICAL MEMBRANE ANTIGEN 1, FAB FRAGMENT OF MONOCLONAL ANTIBODY F8.12.19 | 著者 | Igonet, S, Vulliez-Le Normand, B, Faure, G, Riottot, M.M, Kocken, C.H.M, Thomas, A.W, Bentley, G.A. | 登録日 | 2006-09-07 | 公開日 | 2007-01-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Cross-Reactivity Studies of an Anti-Plasmodium Vivax Apical Membrane Antigen 1 Monoclonal Antibody: Binding and Structural Characterisation. J.Mol.Biol., 366, 2007
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2J5L
| Structure of a Plasmodium falciparum apical membrane antigen 1-Fab F8. 12.19 complex | 分子名称: | APICAL MEMBRANE ANTIGEN 1, FAB FRAGMENT OF MONOCLONAL ANTIBODY F8.12.19 | 著者 | Igonet, S, Vulliez-Le Normand, B, Faure, G, Riottot, M.M, Kocken, C.H.M, Thomas, A.W, Bentley, G.A. | 登録日 | 2006-09-18 | 公開日 | 2007-01-30 | 最終更新日 | 2023-12-13 | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | 主引用文献 | Cross-Reactivity Studies of an Anti-Plasmodium Vivax Apical Membrane Antigen 1 Monoclonal Antibody: Binding and Structural Characterisation. J.Mol.Biol., 366, 2007
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1TUF
| Crystal structure of Diaminopimelate Decarboxylase from m. jannaschi | 分子名称: | AZELAIC ACID, Diaminopimelate decarboxylase | 著者 | Rajashankar, K, Ray, S.R, Bonanno, J.B, Pinho, M.G, He, G, De Lencastre, H, Tomasz, A, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2004-06-24 | 公開日 | 2004-07-20 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Cocrystal structures of diaminopimelate decarboxylase: mechanism, evolution, and inhibition of an antibiotic resistance accessory factor Structure, 10, 2002
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2CCU
| HUMAN HSP90 WITH 4-CHLORO-6-(4-(4-(4-METHANESULPHONYL-BENZYL)- PIERAZIN-1-YL)-1H-PYRAZOL-3-YL)-BENZENE-1,3-DIOL | 分子名称: | 4-CHLORO-6-(4-{4-[4-(METHYLSULFONYL)BENZYL]PIPERAZIN-1-YL}-1H-PYRAZOL-5-YL)BENZENE-1,3-DIOL, HEAT SHOCK PROTEIN HSP-90 ALPHA | 著者 | Barril, X, Beswick, M.C, Collier, A, Drysdale, M.J, Dymock, B.W, Fink, A, Grant, K, Howes, R, Jordan, A.M, Massey, A, Surgenor, A, Wayne, J, Workman, P, Wright, L. | 登録日 | 2006-01-18 | 公開日 | 2006-02-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | 4-Amino derivatives of the Hsp90 inhibitor CCT018159. Bioorg. Med. Chem. Lett., 16, 2006
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2CCT
| HUMAN HSP90 WITH 5-(5-CHLORO-2,4-DIHYDROXY-PHENYL)-4-PIPERAZIN-1-YL- 2H-PYRAZOLE-3-CARBOXYLIC ACID ETHYLAMIDE | 分子名称: | 5-(5-CHLORO-2,4-DIHYDROXYPHENYL)-N-ETHYL-4-PIPERAZIN-1-YL-1H-PYRAZOLE-3-CARBOXAMIDE, HEAT SHOCK PROTEIN HSP-90 ALPHA | 著者 | Barril, X, Beswick, M.C, Collier, A, Drysdale, M.J, Dymock, B.W, Fink, A, Grant, K, Howes, R, Jordan, A.M, Massey, A, Surgenor, A, Wayne, J, Workman, P, Wright, L. | 登録日 | 2006-01-18 | 公開日 | 2006-02-22 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | 4-Amino derivatives of the Hsp90 inhibitor CCT018159. Bioorg. Med. Chem. Lett., 16, 2006
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1TVF
| Crystal Structure of penicillin-binding protein 4 (PBP4) from Staphylococcus aureus | 分子名称: | SULFATE ION, UNKNOWN LIGAND, penicillin binding protein 4 | 著者 | Rajashankar, K.R, Ray, S.S, Bonanno, J.B, Pinho, M, Tomasz, A, Burley, S.K, New York SGX Research Center for Structural Genomics (NYSGXRC) | 登録日 | 2004-06-29 | 公開日 | 2004-07-06 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structure of penicillin-binding protein 4 (PBP4) from Staphylococcus aureus To be Published
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1TT6
| The orthorhombic crystal structure of transthyretin in complex with diethylstilbestrol | 分子名称: | DIETHYLSTILBESTROL, GLYCEROL, SULFATE ION, ... | 著者 | Morais-de-Sa, E.M, Pereira, P.J.B, Saraiva, M.J, Damas, A.M. | 登録日 | 2004-06-22 | 公開日 | 2004-10-12 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | The crystal structure of transthyretin in complex with diethylstilbestrol: a promising template for the design of amyloid inhibitors J.Biol.Chem., 279, 2004
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