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PDB: 5 results

8G49
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BU of 8g49 by Molmil
FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, Oxadiazolone compound 3 bound
Descriptor: Fluorophosphonate-binding serine hydrolase E, methyl 2-formyl-2-[3-methyl-4-(3-phenoxybenzamido)phenyl]hydrazine-1-carboxylate
Authors:Fellner, M, Bakker, A.T, Martin, N.I, Stelt, M.
Deposit date:2023-02-08
Release date:2024-02-21
Method:X-RAY DIFFRACTION (1.6 Å)
Cite:FphE, Staphylococcus aureus fluorophosphonate-binding serine hydrolases E, Oxadiazolone compound 3 bound
To be published
8QQI
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E.coli DNA gyrase in complex with 217 bp substrate DNA and LEI-800
Descriptor: DNA gyrase subunit A, DNA gyrase subunit B, MAGNESIUM ION, ...
Authors:Ghilarov, D, Martin, N.I, van der Stelt, M.
Deposit date:2023-10-04
Release date:2024-06-19
Last modified:2024-07-03
Method:ELECTRON MICROSCOPY (2.9 Å)
Cite:Discovery of isoquinoline sulfonamides as allosteric gyrase inhibitors with activity against fluoroquinolone-resistant bacteria.
Nat.Chem., 2024
7AG5
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BU of 7ag5 by Molmil
Structure of the Laspartomycin C double mutant G4D D-allo-Thr9D-Dap in complex with Geranyl phosphate
Descriptor: (~{E})-13-methyltetradec-2-enoic acid, CALCIUM ION, Geranyl phosphate, ...
Authors:Zeronian, M.R, Pearce, N.M, Wood, T.M, Martin, N.I, Janssen, B.J.C.
Deposit date:2020-09-21
Release date:2022-02-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.04 Å)
Cite:Mechanistic insights into the C55-P targeting lipopeptide antibiotics revealed by structure-activity studies and high-resolution crystal structures
Chem Sci, 13, 2022
7ANY
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Structure of the Laspartomycin C Friulimicin-like mutant in complex with Geranyl phosphate
Descriptor: CADMIUM ION, CALCIUM ION, CHLORIDE ION, ...
Authors:Zeronian, M.R, Pearce, N.M, Lutz, M, Wood, T.M, Martin, N.I, Janssen, B.J.C.
Deposit date:2020-10-13
Release date:2022-02-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (1.135 Å)
Cite:Mechanistic insights into the C55-P targeting lipopeptide antibiotics revealed by structure-activity studies and high-resolution crystal structures
Chem Sci, 13, 2022
5O0Z
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BU of 5o0z by Molmil
Structure of laspartomycin C in complex with geranyl-phosphate
Descriptor: ACETIC ACID, CALCIUM ION, CHLORIDE ION, ...
Authors:Vlieg, H.C, Kleijn, L.H.J, Martin, N.I, Janssen, B.J.C.
Deposit date:2017-05-17
Release date:2017-11-15
Last modified:2024-08-07
Method:X-RAY DIFFRACTION (1.28 Å)
Cite:A High-Resolution Crystal Structure that Reveals Molecular Details of Target Recognition by the Calcium-Dependent Lipopeptide Antibiotic Laspartomycin C.
Angew. Chem. Int. Ed. Engl., 56, 2017

224931

數據於2024-09-11公開中

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