3QKM
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![BU of 3qkm by Molmil](/molmil-images/mine/3qkm) | Spirocyclic sulfonamides as AKT inhibitors | 分子名称: | N-(2-ethoxyethyl)-N-{(2S)-2-hydroxy-3-[(5R)-2-(quinazolin-4-yl)-2,7-diazaspiro[4.5]dec-7-yl]propyl}-2,6-dimethylbenzenesulfonamide, RAC-alpha serine/threonine-protein kinase | 著者 | Xu, R, Banka, A, Blake, J.F, Mitchell, I.S, Wallace, E.M, Gloor, S.L, Martinson, M, Risom, T, Gross, S.D, Morales, T, Vigers, G.P.A, Brandhuber, B.J, Skelton, N.J. | 登録日 | 2011-02-01 | 公開日 | 2011-04-06 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of spirocyclic sulfonamides as potent Akt inhibitors with exquisite selectivity against PKA. Bioorg.Med.Chem.Lett., 21, 2011
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2RLI
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![BU of 2rli by Molmil](/molmil-images/mine/2rli) | Solution structure of Cu(I) human Sco2 | 分子名称: | COPPER (I) ION, SCO2 protein homolog, mitochondrial | 著者 | Banci, L, Bertini, I, Ciofi-baffoni, S, Gerothanassis, I.P, Leontari, I, Martinelli, M, Wang, S, Structural Proteomics in Europe (SPINE), Structural Proteomics in Europe 2 (SPINE-2) | 登録日 | 2007-07-11 | 公開日 | 2007-08-28 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | A Structural Characterization of Human SCO2 Structure, 15, 2007
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2GQL
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![BU of 2gql by Molmil](/molmil-images/mine/2gql) | Solution structure of Human Ni(II)-Sco1 | 分子名称: | NICKEL (II) ION, SCO1 protein homolog, mitochondrial | 著者 | Banci, L, Bertini, I, Calderone, V, Ciofi-Baffoni, S, Mangani, S, Palumaa, P, Martinelli, M, Wang, S, Structural Proteomics in Europe (SPINE) | 登録日 | 2006-04-21 | 公開日 | 2006-06-06 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | A hint for the function of human Sco1 from different structures. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2GQK
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![BU of 2gqk by Molmil](/molmil-images/mine/2gqk) | Solution structure of Human Ni(II)-Sco1 | 分子名称: | NICKEL (II) ION, SCO1 protein homolog, mitochondrial | 著者 | Banci, L, Bertini, I, Calderone, V, Ciofi-Baffoni, S, Mangani, S, Palumaa, P, Martinelli, M, Wang, S, Structural Proteomics in Europe (SPINE) | 登録日 | 2006-04-21 | 公開日 | 2006-06-06 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | A hint for the function of human Sco1 from different structures. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2HRF
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![BU of 2hrf by Molmil](/molmil-images/mine/2hrf) | Solution Structure of Cu(I) P174L HSco1 | 分子名称: | COPPER (I) ION, SCO1 protein homolog, mitochondrial | 著者 | Banci, L, Bertini, I, Ciofi-Baffoni, S, Leontari, I, Martinelli, M, Palumaa, P, Sillard, R, Wang, S, Structural Proteomics in Europe (SPINE) | 登録日 | 2006-07-20 | 公開日 | 2007-01-16 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Human Sco1 functional studies and pathological implications of the P174L mutant. Proc.Natl.Acad.Sci.Usa, 104, 2007
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2HRN
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![BU of 2hrn by Molmil](/molmil-images/mine/2hrn) | Solution Structure of Cu(I) P174L-HSco1 | 分子名称: | COPPER (I) ION, SCO1 protein homolog, mitochondrial | 著者 | Banci, L, Bertini, I, Ciofi-Baffoni, S, Leontari, I, Martinelli, M, Palumaa, P, Sillard, R, Wang, S, Structural Proteomics in Europe (SPINE) | 登録日 | 2006-07-20 | 公開日 | 2007-01-16 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Human Sco1 functional studies and pathological implications of the P174L mutant. Proc.Natl.Acad.Sci.Usa, 104, 2007
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1I5G
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![BU of 1i5g by Molmil](/molmil-images/mine/1i5g) | TRYPAREDOXIN II COMPLEXED WITH GLUTATHIONYLSPERMIDINE | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, GLUTATHIONYLSPERMIDINE, TRYPAREDOXIN II | 著者 | Hofmann, B, Budde, H, Bruns, K, Guerrero, S.A, Kalisz, H.M, Menge, U, Montemartini, M, Nogoceke, E, Steinert, P, Wissing, J.B, Flohe, L, Hecht, H.-J. | 登録日 | 2001-02-27 | 公開日 | 2001-03-14 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Structures of tryparedoxins revealing interaction with trypanothione. Biol.Chem., 382, 2001
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2GGT
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![BU of 2ggt by Molmil](/molmil-images/mine/2ggt) | Crystal structure of human SCO1 complexed with nickel. | 分子名称: | CHLORIDE ION, NICKEL (II) ION, SCO1 protein homolog, ... | 著者 | Banci, L, Bertini, I, Calderone, V, Ciofi-Baffoni, S, Mangani, S, Martinelli, M, Palumaa, P, Wang, S. | 登録日 | 2006-03-24 | 公開日 | 2006-05-16 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | A hint for the function of human Sco1 from different structures. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2RN9
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![BU of 2rn9 by Molmil](/molmil-images/mine/2rn9) | Solution structure of human apoCox17 | 分子名称: | Cytochrome c oxidase copper chaperone | 著者 | Banci, L, Bertini, I, Ciofi-Baffoni, S, Janicka, A, Martinelli, M, Kozlowski, H, Palumaa, P. | 登録日 | 2007-12-08 | 公開日 | 2007-12-18 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | A structural-dynamical characterization of human cox17 J.Biol.Chem., 283, 2008
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2RNB
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![BU of 2rnb by Molmil](/molmil-images/mine/2rnb) | Solution structure of human Cu(I)Cox17 | 分子名称: | COPPER (I) ION, Cytochrome c oxidase copper chaperone | 著者 | Banci, L, Bertini, I, Ciofi-Baffoni, S, Janicka, A, Martinelli, M, Kozlowski, H, Palumaa, P. | 登録日 | 2007-12-08 | 公開日 | 2007-12-18 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | A structural-dynamical characterization of human cox17 J.Biol.Chem., 283, 2008
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8B2D
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![BU of 8b2d by Molmil](/molmil-images/mine/8b2d) | CRYSTAL STRUCTURE OF BACTERIAL FLAVIN CONTAINING MONOOXYGENASE THERMORESISTANT MUTANT, IN COMPLEX WITH NADP+ | 分子名称: | 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, ... | 著者 | Cea-Rama, I, Sanz-Aparicio, J, Ferrer Martinez, M, Goris, M, Bjerga, G. | 登録日 | 2022-09-13 | 公開日 | 2023-06-14 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.62 Å) | 主引用文献 | Increased Thermostability of an Engineered Flavin-Containing Monooxygenase to Remediate Trimethylamine in Fish Protein Hydrolysates. Appl.Environ.Microbiol., 89, 2023
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2GQM
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![BU of 2gqm by Molmil](/molmil-images/mine/2gqm) | Solution structure of Human Cu(I)-Sco1 | 分子名称: | COPPER (I) ION, SCO1 protein homolog, mitochondrial | 著者 | Banci, L, Bertini, I, Calderone, V, Ciofi-Baffoni, S, Mangani, S, Palumaa, P, Martinelli, M, Wang, S, Structural Proteomics in Europe (SPINE) | 登録日 | 2006-04-21 | 公開日 | 2006-06-06 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | A hint for the function of human Sco1 from different structures. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2GVP
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![BU of 2gvp by Molmil](/molmil-images/mine/2gvp) | Solution structure of Human apo Sco1 | 分子名称: | SCO1 protein homolog, mitochondrial | 著者 | Banci, L, Bertini, I, Calderone, V, Ciofi-Baffoni, S, Mangani, S, Paulmaa, P, Martinelli, M, Wang, S, Structural Proteomics in Europe (SPINE) | 登録日 | 2006-05-03 | 公開日 | 2006-06-06 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | A hint for the function of human Sco1 from different structures. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2GT5
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![BU of 2gt5 by Molmil](/molmil-images/mine/2gt5) | Solution structure of apo Human Sco1 | 分子名称: | SCO1 protein homolog, mitochondrial | 著者 | Banci, L, Bertini, I, Calderone, V, Ciofi-Baffoni, S, Mangani, S, Palumaa, P, Martinelli, M, Wang, S, Structural Proteomics in Europe (SPINE) | 登録日 | 2006-04-27 | 公開日 | 2006-06-06 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | A hint for the function of human Sco1 from different structures. Proc.Natl.Acad.Sci.Usa, 103, 2006
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2GT6
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![BU of 2gt6 by Molmil](/molmil-images/mine/2gt6) | Solution structure of Human Cu(I) Sco1 | 分子名称: | COPPER (I) ION, SCO1 protein homolog, mitochondrial | 著者 | Banci, L, Bertini, I, Calderone, V, Ciofi-Baffoni, S, Mangani, S, Palumaa, P, Martinelli, M, Wang, S, Structural Proteomics in Europe (SPINE) | 登録日 | 2006-04-27 | 公開日 | 2006-06-06 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | A hint for the function of human Sco1 from different structures. Proc.Natl.Acad.Sci.Usa, 103, 2006
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1FG4
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![BU of 1fg4 by Molmil](/molmil-images/mine/1fg4) | STRUCTURE OF TRYPAREDOXIN II | 分子名称: | TRYPAREDOXIN II | 著者 | Hofmann, B, Budde, H, Bruns, K, Guerrero, S.A, Kalisz, H.M, Menge, U, Montemartini, M, Nogoceke, E, Steinert, P, Wissing, J.B, Flohe, L, Hecht, H.J. | 登録日 | 2000-07-28 | 公開日 | 2001-04-25 | 最終更新日 | 2017-10-04 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of tryparedoxins revealing interaction with trypanothione. Biol.Chem., 382, 2001
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1BW0
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![BU of 1bw0 by Molmil](/molmil-images/mine/1bw0) | CRYSTAL STRUCTURE OF TYROSINE AMINOTRANSFERASE FROM TRYPANOSOMA CRUZI | 分子名称: | PROTEIN (TYROSINE AMINOTRANSFERASE) | 著者 | Blankenfeldt, W, Montemartini, M, Hunter, G.R, Kalisz, H.M, Nowicki, C, Hecht, H.J. | 登録日 | 1998-09-28 | 公開日 | 1999-09-27 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of Trypanosoma cruzi tyrosine aminotransferase: substrate specificity is influenced by cofactor binding mode. Protein Sci., 8, 1999
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2KDU
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![BU of 2kdu by Molmil](/molmil-images/mine/2kdu) | Structural basis of the Munc13-1/Ca2+-Calmodulin interaction: A novel 1-26 calmodulin binding motif with a bipartite binding mode | 分子名称: | CALCIUM ION, Calmodulin, Protein unc-13 homolog A | 著者 | Rodriguez-Castaneda, F.A, Maestre-Martinez, M, Coudevylle, N, Dimova, K, Jahn, O, Junge, H, Becker, S, Brose, N, Carlomagno, T, Griesinger, C. | 登録日 | 2009-01-19 | 公開日 | 2009-12-15 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Modular architecture of Munc13/calmodulin complexes: dual regulation by Ca2+ and possible function in short-term synaptic plasticity. Embo J., 29, 2010
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1EWX
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![BU of 1ewx by Molmil](/molmil-images/mine/1ewx) | Crystal structure of native tryparedoxin I from Crithidia fasciculata | 分子名称: | TRYPAREDOXIN I | 著者 | Hofmann, B, Guerrero, S.A, Kalisz, H.M, Menge, U, Nogoceke, E, Montemartini, M, Singh, M, Flohe, L, Hecht, H.J. | 登録日 | 2000-04-28 | 公開日 | 2000-05-10 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structures of tryparedoxins revealing interaction with trypanothione. Biol.Chem., 382, 2001
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1EZK
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![BU of 1ezk by Molmil](/molmil-images/mine/1ezk) | Crystal structure of recombinant tryparedoxin I | 分子名称: | TRYPAREDOXIN I | 著者 | Hofmann, B, Guerrero, S.A, Kalisz, H.M, Menge, U, Nogoceke, E, Montemartini, M, Singh, M, Flohe, L, Hecht, H.J. | 登録日 | 2000-05-11 | 公開日 | 2000-05-24 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structures of tryparedoxins revealing interaction with trypanothione. Biol.Chem., 382, 2001
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2N6J
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![BU of 2n6j by Molmil](/molmil-images/mine/2n6j) | Solution structure of Zmp1, a zinc-dependent metalloprotease secreted by Clostridium difficile | 分子名称: | ZINC ION, Zinc metalloprotease Zmp1 | 著者 | Banci, L, Cantini, F, Scarselli, M, Rubino, J.T, Martinelli, M. | 登録日 | 2015-08-24 | 公開日 | 2016-01-13 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural characterization of zinc-bound Zmp1, a zinc-dependent metalloprotease secreted by Clostridium difficile. J.Biol.Inorg.Chem., 21, 2016
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5OHE
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![BU of 5ohe by Molmil](/molmil-images/mine/5ohe) | Globin sensor domain of AfGcHK (FeIII form) in complex with cyanide | 分子名称: | CHLORIDE ION, CYANIDE ION, Globin-coupled histidine kinase, ... | 著者 | Skalova, T, Kolenko, P, Dohnalek, J, Stranava, M, Martinkova, M. | 登録日 | 2017-07-16 | 公開日 | 2017-11-08 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | 主引用文献 | Coordination and redox state-dependent structural changes of the heme-based oxygen sensor AfGcHK associated with intraprotein signal transduction. J. Biol. Chem., 292, 2017
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5OHF
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![BU of 5ohf by Molmil](/molmil-images/mine/5ohf) | Globin sensor domain of AfGcHK (FeIII form) in complex with cyanide, partially reduced | 分子名称: | CHLORIDE ION, CYANIDE ION, Globin-coupled histidine kinase, ... | 著者 | Skalova, T, Kolenko, P, Dohnalek, J, Stranava, M, Martinkova, M. | 登録日 | 2017-07-16 | 公開日 | 2017-11-08 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Coordination and redox state-dependent structural changes of the heme-based oxygen sensor AfGcHK associated with intraprotein signal transduction. J. Biol. Chem., 292, 2017
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4DMW
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![BU of 4dmw by Molmil](/molmil-images/mine/4dmw) | Crystal structure of the GT domain of Clostridium difficile toxin A (TcdA) in complex with UDP and Manganese | 分子名称: | MANGANESE (II) ION, Toxin A, URIDINE-5'-DIPHOSPHATE | 著者 | Malito, E, D'Urzo, N, Bottomley, M.J, Biancucci, M, Scarselli, M, Maione, D, Martinelli, M. | 登録日 | 2012-02-08 | 公開日 | 2012-07-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The structure of Clostridium difficile toxin A glucosyltransferase domain bound to Mn2+ and UDP provides insights into glucosyltransferase activity and product release. Febs J., 279, 2012
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4DMV
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![BU of 4dmv by Molmil](/molmil-images/mine/4dmv) | Crystal structure of the GT domain of Clostridium difficile Toxin A | 分子名称: | Toxin A | 著者 | Malito, E, D'Urzo, N, Bottomley, M.J, Biancucci, M, Maione, D, Scarselli, M, Martinelli, M. | 登録日 | 2012-02-08 | 公開日 | 2012-07-18 | 最終更新日 | 2023-09-13 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | The structure of Clostridium difficile toxin A glucosyltransferase domain bound to Mn2+ and UDP provides insights into glucosyltransferase activity and product release. Febs J., 279, 2012
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