1L5A
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![BU of 1l5a by Molmil](/molmil-images/mine/1l5a) | Crystal Structure of VibH, an NRPS Condensation Enzyme | Descriptor: | amide synthase | Authors: | Keating, T.A, Marshall, C.G, Walsh, C.T, Keating, A.E. | Deposit date: | 2002-03-06 | Release date: | 2002-06-26 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.55 Å) | Cite: | The structure of VibH represents nonribosomal peptide synthetase condensation, cyclization and epimerization domains. Nat.Struct.Biol., 9, 2002
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3RVG
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![BU of 3rvg by Molmil](/molmil-images/mine/3rvg) | Crystals structure of Jak2 with a 1-amino-5H-pyrido[4,3-b]indol-4-carboxamide inhibitor | Descriptor: | 1-(cyclohexylamino)-7-(1-methyl-1H-pyrazol-4-yl)-5H-pyrido[4,3-b]indole-4-carboxamide, Tyrosine-protein kinase JAK2 | Authors: | Lim, J, Taoka, B, Otte, R.D, Spencer, K, Dinsmore, C.J, Altman, M.D, Chan, G, Rosenstein, C, Sharma, S, Su, H.P, Szewczak, A.A, Xu, L, Yin, H, Zugay-Murphy, J, Marshall, C.G, Young, J.R. | Deposit date: | 2011-05-06 | Release date: | 2012-03-21 | Last modified: | 2017-11-08 | Method: | X-RAY DIFFRACTION (2.498 Å) | Cite: | Discovery of 1-amino-5H-pyrido[4,3-b]indol-4-carboxamide inhibitors of Janus kinase 2 (JAK2) for the treatment of myeloproliferative disorders. J.Med.Chem., 54, 2011
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