8GOP
| SARS-CoV-2 specific private TCR RLQ7 | 分子名称: | SARS-CoV-2 specific private TCR RLQ7 alpha, SARS-CoV-2 specific private TCR RLQ7 beta | 著者 | Wu, D, Mariuzza, R.A. | 登録日 | 2022-08-25 | 公開日 | 2023-03-01 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural insights into protection against a SARS-CoV-2 spike variant by T cell receptor (TCR) diversity. J.Biol.Chem., 299, 2023
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8GOM
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4K5U
| Recognition of the BG-H Antigen by a Lamprey Variable Lymphocyte Receptor | 分子名称: | Variable lymphocyte receptor, beta-D-galactopyranose | 著者 | Luo, M, Velikovsky, C.A, Yang, X.B, Mariuzza, R.A. | 登録日 | 2013-04-15 | 公開日 | 2013-06-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.698 Å) | 主引用文献 | Recognition of the thomsen-friedenreich pancarcinoma carbohydrate antigen by a lamprey variable lymphocyte receptor. J.Biol.Chem., 288, 2013
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4K79
| Recognition of the Thomsen-Friedenreich Antigen by a Lamprey Variable Lymphocyte Receptor | 分子名称: | Variable lymphocyte receptor, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose | 著者 | Luo, M, Velikovsky, C.A, Yang, X.B, Mariuzza, R.A. | 登録日 | 2013-04-16 | 公開日 | 2013-06-26 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Recognition of the thomsen-friedenreich pancarcinoma carbohydrate antigen by a lamprey variable lymphocyte receptor. J.Biol.Chem., 288, 2013
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7REV
| Co-crystal structure of Chaetomium glucosidase with compound 3 | 分子名称: | (2R,3R,4R,5S)-1-[(4-{[4-(furan-2-yl)-2-methylanilino]methyl}phenyl)methyl]-2-(hydroxymethyl)piperidine-3,4,5-triol, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Karade, S.S, Mariuzza, R.A. | 登録日 | 2021-07-13 | 公開日 | 2022-08-03 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure-Based Design of Potent Iminosugar Inhibitors of Endoplasmic Reticulum alpha-Glucosidase I with Anti-SARS-CoV-2 Activity. J.Med.Chem., 66, 2023
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7R6J
| Co-crystal structure of Chaetomium glucosidase with compound 1 | 分子名称: | (2R,3R,4R,5S)-2-(hydroxymethyl)-1-[(3-{[3-methyl-5-(pyrimidin-2-yl)anilino]methyl}phenyl)methyl]piperidine-3,4,5-triol, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Karade, S.S, Mariuzza, R.A. | 登録日 | 2021-06-22 | 公開日 | 2022-07-06 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.905 Å) | 主引用文献 | Structure-Based Design of Potent Iminosugar Inhibitors of Endoplasmic Reticulum alpha-Glucosidase I with Anti-SARS-CoV-2 Activity. J.Med.Chem., 66, 2023
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7RM4
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4Z0X
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4ZSO
| Crystal structure of a complex between B7-H6, a tumor cell ligand for natural cytotoxicity receptor NKp30, and an inhibitory antibody | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ACETIC ACID, ... | 著者 | Xu, X, Li, Y, Mariuzza, R.A. | 登録日 | 2015-05-13 | 公開日 | 2016-05-18 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal structure of a complex between B7-H6, a tumor cell ligand for natural cytotoxicity receptor NKp30, and an inhibitory antibody to be published
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1JCK
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2PTT
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2PTU
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2PTV
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1TVD
| VARIABLE DOMAIN OF T CELL RECEPTOR DELTA CHAIN | 分子名称: | T CELL RECEPTOR | 著者 | Li, H.M, Lebedeva, M.I, Llera, A.S, Fields, B.A, Brenner, M.B, Mariuzza, R.A. | 登録日 | 1997-10-19 | 公開日 | 1998-04-22 | 最終更新日 | 2011-07-13 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Structure of the Vdelta domain of a human gammadelta T-cell antigen receptor. Nature, 391, 1998
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7N1E
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7N1C
| SARS-CoV-2 RLQ peptide-specific TCR pRLQ3 | 分子名称: | pRLQ3 T cell receptor alpha chain, pRLQ3 T cell receptor beta chain | 著者 | Wu, D, Mariuzza, R.A. | 登録日 | 2021-05-27 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.881 Å) | 主引用文献 | Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors. Nat Commun, 13, 2022
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7N1A
| SARS-CoV-2 YLQ peptide binds to HLA-A2 | 分子名称: | Beta-2-microglobulin, MHC class I antigen, A-2 alpha chain, ... | 著者 | Wu, D, Mariuzza, R.A. | 登録日 | 2021-05-27 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.065 Å) | 主引用文献 | Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors. Nat Commun, 13, 2022
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7N1B
| SARS-CoV-2 RLQ peptide binds to HLA-A2 | 分子名称: | Beta-2-microglobulin, MHC class I antigen, A-2 alpha chain, ... | 著者 | Wu, D, Mariuzza, R.A. | 登録日 | 2021-05-27 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.81 Å) | 主引用文献 | Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors. Nat Commun, 13, 2022
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7N1F
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7N1D
| SARS-CoV-2 YLQ peptide-specific TCR pYLQ7 | 分子名称: | pYLQ7 T cell receptor alpha chain, pYLQ7 T cell receptor beta chain | 著者 | Wu, D, Mariuzza, R.A. | 登録日 | 2021-05-27 | 公開日 | 2021-07-28 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors. Nat Commun, 13, 2022
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2IAM
| Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR | 分子名称: | 15-mer peptide from Triosephosphate isomerase, CD4+ T cell receptor E8 alpha chain, CD4+ T cell receptor E8 beta chain, ... | 著者 | Deng, L, Langley, R.J, Mariuzza, R.A. | 登録日 | 2006-09-08 | 公開日 | 2007-04-03 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor Nat.Immunol., 8, 2007
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2IAN
| Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR | 分子名称: | 15-mer peptide from Triosephosphate isomerase, CD4+ T cell receptor E8 alpha chain, CD4+ T cell receptor E8 beta chain, ... | 著者 | Deng, L, Langley, R.J, Mariuzza, R.A. | 登録日 | 2006-09-08 | 公開日 | 2007-04-03 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | 主引用文献 | Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor Nat.Immunol., 8, 2007
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2IAL
| Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR | 分子名称: | CD4+ T cell receptor E8 alpha chain, CD4+ T cell receptor E8 beta chain | 著者 | Deng, L, Langley, R.J, Mariuzza, R.A. | 登録日 | 2006-09-08 | 公開日 | 2007-04-03 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor Nat.Immunol., 8, 2007
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3T0E
| Crystal structure of a complete ternary complex of T cell receptor, peptide-MHC and CD4 | 分子名称: | HLA class II histocompatibility antigen, DR alpha chain, DRB1-4 beta chain, ... | 著者 | Yin, Y, Mariuzza, R.A. | 登録日 | 2011-07-20 | 公開日 | 2012-03-07 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (4 Å) | 主引用文献 | Crystal structure of a complete ternary complex of T-cell receptor, peptide-MHC, and CD4. Proc.Natl.Acad.Sci.USA, 109, 2012
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2G9H
| Crystal Structure of Staphylococcal Enterotoxin I (SEI) in Complex with a Human MHC class II Molecule | 分子名称: | 1,4-DIETHYLENE DIOXIDE, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, HLA class II histocompatibility antigen, ... | 著者 | Fernandez, M.M, Guan, R, Malchiodi, E.L, Mariuzza, R.A. | 登録日 | 2006-03-06 | 公開日 | 2006-07-11 | 最終更新日 | 2023-08-30 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal structure of staphylococcal enterotoxin I (SEI) in complex with a human major histocompatibility complex class II molecule. J.Biol.Chem., 281, 2006
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