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PDB: 173 results
1ZGL
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Crystal structure of 3A6 TCR bound to MBP/HLA-DR2a
Descriptor: HLA class II histocompatibility antigen, DR alpha chain, Myelin basic protein, ...
Authors:Li, Y, Huang, Y, Lue, J, Quandt, J.A, Martin, R, Mariuzza, R.A.
Deposit date:2005-04-21
Release date:2005-10-18
Last modified:2020-02-19
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structure of a human autoimmune TCR bound to a myelin basic protein self-peptide and a multiple sclerosis-associated MHC class II molecule.
Embo J., 24, 2005
1YWO
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Phospholipase Cgamma1 SH3 in complex with a SLP-76 motif
Descriptor: 1-phosphatidylinositol-4,5-bisphosphate phosphodiesterase gamma 1, Lymphocyte cytosolic protein 2
Authors:Deng, L, Velikovsky, C.A, Swaminathan, C.P, Cho, S, Mariuzza, R.A.
Deposit date:2005-02-18
Release date:2005-08-16
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.81 Å)
Cite:Structural Basis for Recognition of the T Cell Adaptor Protein SLP-76 by the SH3 Domain of Phospholipase Cgamma1
J.Mol.Biol., 352, 2005
1XGQ
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Structure for antibody HyHEL-63 Y33V mutant complexed with hen egg lysozyme
Descriptor: Lysozyme C, antibody kappa heavy chain, antibody kappa light chain
Authors:Li, Y, Mariuzza, R.A.
Deposit date:2004-09-17
Release date:2005-09-06
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Magnitude of the hydrophobic effect at central versus peripheral sites in protein-protein interfaces
Structure, 13, 2005
1DDH
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MHC CLASS I H-2DD HEAVY CHAIN COMPLEXED WITH BETA-2 MICROGLOBULIN AND AN IMMUNODOMINANT PEPTIDE P18-I10 FROM THE HUMAN IMMUNODEFICIENCY VIRUS ENVELOPE GLYCOPROTEIN 120
Descriptor: BETA-2 MICROGLOBULIN, HUMAN IMMUNODEFICIENCY VIRUS ENVELOPE GLYCOPROTEIN 120, MHC CLASS I H-2DD HEAVY CHAIN
Authors:Li, H, Margulies, D.H, Mariuzza, R.A.
Deposit date:1998-06-22
Release date:1999-01-13
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (3.1 Å)
Cite:Three-dimensional structure of H-2Dd complexed with an immunodominant peptide from human immunodeficiency virus envelope glycoprotein 120.
J.Mol.Biol., 283, 1998
1DQJ
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CRYSTAL STRUCTURE OF THE ANTI-LYSOZYME ANTIBODY HYHEL-63 COMPLEXED WITH HEN EGG WHITE LYSOZYME
Descriptor: ANTI-LYSOZYME ANTIBODY HYHEL-63 (HEAVY CHAIN), ANTI-LYSOZYME ANTIBODY HYHEL-63 (LIGHT CHAIN), LYSOZYME
Authors:Li, H, Mariuzza, R.A.
Deposit date:2000-01-04
Release date:2000-01-19
Last modified:2021-07-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:Three-dimensional structures of the free and antigen-bound Fab from monoclonal antilysozyme antibody HyHEL-63(,).
Biochemistry, 39, 2000
1FM5
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CRYSTAL STRUCTURE OF HUMAN CD69
Descriptor: EARLY ACTIVATION ANTIGEN CD69
Authors:Natarajan, K, Sawicki, M.W, Margulies, D.H, Mariuzza, R.A.
Deposit date:2000-08-16
Release date:2000-12-18
Last modified:2016-09-21
Method:X-RAY DIFFRACTION (2.27 Å)
Cite:Crystal structure of human CD69: a C-type lectin-like activation marker of hematopoietic cells.
Biochemistry, 39, 2000
1G7H
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CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3(VLW92A)
Descriptor: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C
Authors:Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
Deposit date:2000-11-10
Release date:2000-11-22
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
1G7J
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CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92H)
Descriptor: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C
Authors:Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
Deposit date:2000-11-10
Release date:2000-11-22
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
1G7M
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CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92V)
Descriptor: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C
Authors:Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
Deposit date:2000-11-10
Release date:2000-11-22
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
1G7L
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CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92S)
Descriptor: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C
Authors:Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
Deposit date:2000-11-10
Release date:2000-11-22
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
1DQM
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CRYSTAL STRUCTURE OF ANTI-LYSOZYME ANTIBODY
Descriptor: ANTI-LYSOZYME ANTIBODY HYHEL-63 (HEAVY CHAIN), ANTI-LYSOZYME ANTIBODY HYHEL-63 (LIGHT CHAIN)
Authors:Li, H, Mariuzza, R.A.
Deposit date:2000-01-04
Release date:2000-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Three-dimensional structures of the free and antigen-bound Fab from monoclonal antilysozyme antibody HyHEL-63(,).
Biochemistry, 39, 2000
1G7I
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CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92F)
Descriptor: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C, PHOSPHATE ION
Authors:Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
Deposit date:2000-11-10
Release date:2000-11-22
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
1DQQ
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CRYSTAL STRUCTURE OF ANTI-LYSOZYME ANTIBODY HYHEL-63
Descriptor: ANTI-LYSOZYME ANTIBODY HYHEL-63 (HEAVY CHAIN), ANTI-LYSOZYME ANTIBODY HYHEL-63 (LIGHT CHAIN)
Authors:Li, H, Mariuzza, R.A.
Deposit date:2000-01-04
Release date:2000-01-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Three-dimensional structures of the free and antigen-bound Fab from monoclonal antilysozyme antibody HyHEL-63(,).
Biochemistry, 39, 2000
1JNE
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Crystal structure of imaginal disc growth factor-2
Descriptor: Imaginal disc growth factor-2, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Varela, P.F, Llera, A.S, Mariuzza, R.A, Tormo, J.
Deposit date:2001-07-23
Release date:2002-05-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Crystal structure of imaginal disc growth factor-2. A member of a new family of growth-promoting glycoproteins from Drosophila melanogaster.
J.Biol.Chem., 277, 2002
1JWM
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Crystal Structure of the Complex of the MHC Class II Molecule HLA-DR1(HA peptide 306-318) with the Superantigen SEC3
Descriptor: Enterotoxin type C-3, HA peptide, HLA class II histocompatibility antigen, ...
Authors:Sundberg, E.J, Andersen, P.S, Schlievert, P.M, Karjalainen, K, Mariuzza, R.A.
Deposit date:2001-09-04
Release date:2003-07-08
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structural, energetic, and functional analysis of a protein-protein interface at distinct stages of affinity maturation
Structure, 11, 2003
1JND
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Crystal structure of imaginal disc growth factor-2
Descriptor: Imaginal disc growth factor-2, alpha-D-mannopyranose-(1-3)-beta-D-mannopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose
Authors:Varela, P.F, Llera, A.S, Mariuzza, R.A, Tormo, J.
Deposit date:2001-07-23
Release date:2002-05-01
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Crystal structure of imaginal disc growth factor-2. A member of a new family of growth-promoting glycoproteins from Drosophila melanogaster.
J.Biol.Chem., 277, 2002
1JWU
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Crystal Structure of the Complex of the MHC Class II Molecule HLA-DR1 (HA peptide 306-318) with the superantigen SEC3 Variant 3B2
Descriptor: Enterotoxin type C-3, HA peptide, HLA class II histocompatibility antigen, ...
Authors:Sundberg, E.J, Andersen, P.S, Schlievert, P.M, Karjalainen, K, Mariuzza, R.A.
Deposit date:2001-09-05
Release date:2003-07-08
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural, energetic, and functional analysis of a protein-protein interface at distinct stages of affinity maturation
Structure, 11, 2003
1KLG
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Crystal structure of HLA-DR1/TPI(23-37, Thr28-->Ile mutant) complexed with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2)
Descriptor: ENTEROTOXIN TYPE C-3, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, ...
Authors:Sundberg, E.J, Sawicki, M.W, Andersen, P.S, Sidney, J, Sette, A, Mariuzza, R.A.
Deposit date:2001-12-11
Release date:2002-08-02
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line.
J.Mol.Biol., 319, 2002
1KTK
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Complex of Streptococcal pyrogenic enterotoxin C (SpeC) with a human T cell receptor beta chain (Vbeta2.1)
Descriptor: Exotoxin type C, T-cell receptor beta chain
Authors:Sundberg, E.J, Li, H, Llera, A.S, McCormick, J.K, Tormo, J, Karjalainen, K, Schlievert, P.M, Mariuzza, R.A.
Deposit date:2002-01-16
Release date:2002-06-07
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexes.
Structure, 10, 2002
1KLU
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Crystal structure of HLA-DR1/TPI(23-37) complexed with staphylococcal enterotoxin C3 variant 3B2 (SEC3-3B2)
Descriptor: ENTEROTOXIN TYPE C-3, HLA CLASS II HISTOCOMPATIBILITY ANTIGEN, DR ALPHA CHAIN, ...
Authors:Sundberg, E.J, Sawicki, M.W, Andersen, P.S, Sidney, J, Sette, A, Mariuzza, R.A.
Deposit date:2001-12-12
Release date:2002-08-02
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.93 Å)
Cite:Minor structural changes in a mutated human melanoma antigen correspond to dramatically enhanced stimulation of a CD4+ tumor-infiltrating lymphocyte line.
J.Mol.Biol., 319, 2002
1L0Y
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T cell receptor beta chain complexed with superantigen SpeA soaked with zinc
Descriptor: 14.3.d T cell receptor beta chain, Exotoxin type A, GLYCEROL, ...
Authors:Li, H, Sundberg, E.J, Mariuzza, R.A.
Deposit date:2002-02-14
Release date:2002-04-03
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Structures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexes.
Structure, 10, 2002
1JWS
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Crystal Structure of the Complex of the MHC Class II Molecule HLA-DR1 (HA peptide 306-318) with the Superantigen SEC3 Variant 3B1
Descriptor: Enterotoxin type C-3, HA peptide, HLA class II histocompatibility antigen, ...
Authors:Sundberg, E.J, Andersen, P.S, Schlievert, P.M, Karjalainen, K, Mariuzza, R.A.
Deposit date:2001-09-05
Release date:2003-07-08
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structural, energetic, and functional analysis of a protein-protein interface at distinct stages of affinity maturation
Structure, 11, 2003
1L0X
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TCR beta chain complexed with streptococcal superantigen SpeA
Descriptor: 14.3.d T cell receptor beta chain, Exotoxin type A, GLYCEROL
Authors:Li, H, Sundberg, E.J, Mariuzza, R.A.
Deposit date:2002-02-14
Release date:2002-04-03
Last modified:2023-08-16
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structures of two streptococcal superantigens bound to TCR beta chains reveal diversity in the architecture of T cell signaling complexes.
Structure, 10, 2002

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