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PDB: 180 results

1G7M
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CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92V)
Descriptor: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C
Authors:Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
Deposit date:2000-11-10
Release date:2000-11-22
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
1G7L
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CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92S)
Descriptor: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C
Authors:Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
Deposit date:2000-11-10
Release date:2000-11-22
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (2 Å)
Cite:Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
1G7I
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CRYSTAL STRUCTURE OF HEN EGG WHITE LYSOZYME (HEL) COMPLEXED WITH THE MUTANT ANTI-HEL MONOCLONAL ANTIBODY D1.3 (VLW92F)
Descriptor: ANTI-HEN EGG WHITE LYSOZYME MONOCLONAL ANTIBODY D1.3, LYSOZYME C, PHOSPHATE ION
Authors:Sundberg, E.J, Urrutia, M, Braden, B.C, Isern, J, Mariuzza, R.A.
Deposit date:2000-11-10
Release date:2000-11-22
Last modified:2021-10-27
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Estimation of the hydrophobic effect in an antigen-antibody protein-protein interface.
Biochemistry, 39, 2000
5TEZ
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BU of 5tez by Molmil
TCR F50 recgonizing M1-HLA-A2
Descriptor: Beta-2-microglobulin, GLY-ILE-LEU-GLY-PHE-VAL-PHE-THR-LEU, HLA class I histocompatibility antigen, ...
Authors:Yang, X, Mariuzza, R.A.
Deposit date:2016-09-23
Release date:2017-09-27
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structural basis for clonal diversity of the human T-cell response to a dominant influenza virus epitope.
J. Biol. Chem., 292, 2017
4K5U
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BU of 4k5u by Molmil
Recognition of the BG-H Antigen by a Lamprey Variable Lymphocyte Receptor
Descriptor: Variable lymphocyte receptor, beta-D-galactopyranose
Authors:Luo, M, Velikovsky, C.A, Yang, X.B, Mariuzza, R.A.
Deposit date:2013-04-15
Release date:2013-06-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.698 Å)
Cite:Recognition of the thomsen-friedenreich pancarcinoma carbohydrate antigen by a lamprey variable lymphocyte receptor.
J.Biol.Chem., 288, 2013
4K79
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Recognition of the Thomsen-Friedenreich Antigen by a Lamprey Variable Lymphocyte Receptor
Descriptor: Variable lymphocyte receptor, beta-D-galactopyranose-(1-3)-2-acetamido-2-deoxy-alpha-D-galactopyranose
Authors:Luo, M, Velikovsky, C.A, Yang, X.B, Mariuzza, R.A.
Deposit date:2013-04-16
Release date:2013-06-26
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Recognition of the thomsen-friedenreich pancarcinoma carbohydrate antigen by a lamprey variable lymphocyte receptor.
J.Biol.Chem., 288, 2013
3G3B
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Structure of a lamprey variable lymphocyte receptor mutant in complex with a protein antigen
Descriptor: Lysozyme C, variable lymphocyte receptor VLRB.2D
Authors:Deng, L, Velikovsky, C.A, Mariuzza, R.A.
Deposit date:2009-02-02
Release date:2009-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.4 Å)
Cite:Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen.
Nat.Struct.Mol.Biol., 16, 2009
3G3A
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Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen
Descriptor: Lysozyme C, Variable lymphocyte receptor VLRB.2D
Authors:Deng, L, Velikovsky, C.A, Mariuzza, R.A.
Deposit date:2009-02-02
Release date:2009-06-23
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structure of a lamprey variable lymphocyte receptor in complex with a protein antigen.
Nat.Struct.Mol.Biol., 16, 2009
8TFE
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BU of 8tfe by Molmil
Crystal structure of Fab fragment of anti-HCV E2 antibody (CBH-7)
Descriptor: 1,2-ETHANEDIOL, CBH-7 Heavy chain, CBH-7 Light chain, ...
Authors:Shahid, S, Mariuzza, R.A.
Deposit date:2023-07-10
Release date:2024-07-17
Method:X-RAY DIFFRACTION (1.62 Å)
Cite:Crystal structure of Fab fragment of anti-HCV E2 antibody (CBH-7)
To Be Published
5D2L
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BU of 5d2l by Molmil
Crystal structure of TCR C7 in complex with HCMV NLV epitope presented by HLA-A2
Descriptor: ASN-LEU-VAL-PRO-MET-VAL-ALA-THR-VAL, Beta-2-microglobulin, C7 TCR alpha chain, ...
Authors:Gao, M, Mariuzza, R.A.
Deposit date:2015-08-05
Release date:2015-10-07
Last modified:2023-09-27
Method:X-RAY DIFFRACTION (3.511 Å)
Cite:Structural Basis for Clonal Diversity of the Public T Cell Response to a Dominant Human Cytomegalovirus Epitope.
J.Biol.Chem., 290, 2015
7N1E
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SARS-CoV-2 RLQ peptide-specific TCR pRLQ3 binds to RLQ-HLA-A2
Descriptor: Beta-2-microglobulin, MHC class I antigen, A-2 alpha chain, ...
Authors:Wu, D, Mariuzza, R.A.
Deposit date:2021-05-27
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors.
Nat Commun, 13, 2022
7N1C
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SARS-CoV-2 RLQ peptide-specific TCR pRLQ3
Descriptor: pRLQ3 T cell receptor alpha chain, pRLQ3 T cell receptor beta chain
Authors:Wu, D, Mariuzza, R.A.
Deposit date:2021-05-27
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.881 Å)
Cite:Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors.
Nat Commun, 13, 2022
7N1A
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SARS-CoV-2 YLQ peptide binds to HLA-A2
Descriptor: Beta-2-microglobulin, MHC class I antigen, A-2 alpha chain, ...
Authors:Wu, D, Mariuzza, R.A.
Deposit date:2021-05-27
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.065 Å)
Cite:Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors.
Nat Commun, 13, 2022
7N1B
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SARS-CoV-2 RLQ peptide binds to HLA-A2
Descriptor: Beta-2-microglobulin, MHC class I antigen, A-2 alpha chain, ...
Authors:Wu, D, Mariuzza, R.A.
Deposit date:2021-05-27
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.81 Å)
Cite:Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors.
Nat Commun, 13, 2022
7N1F
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BU of 7n1f by Molmil
SARS-CoV-2 YLQ peptide-specific TCR pYLQ7 binds to YLQ-HLA-A2
Descriptor: Beta-2-microglobulin, MHC class I antigen, A-2 alpha chain, ...
Authors:Wu, D, Mariuzza, R.A.
Deposit date:2021-05-27
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.393 Å)
Cite:Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors.
Nat Commun, 13, 2022
7N1D
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BU of 7n1d by Molmil
SARS-CoV-2 YLQ peptide-specific TCR pYLQ7
Descriptor: pYLQ7 T cell receptor alpha chain, pYLQ7 T cell receptor beta chain
Authors:Wu, D, Mariuzza, R.A.
Deposit date:2021-05-27
Release date:2021-07-28
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Structural assessment of HLA-A2-restricted SARS-CoV-2 spike epitopes recognized by public and private T-cell receptors.
Nat Commun, 13, 2022
7RD2
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Co-crystal structure of Chaetomium glucosidase with compound 2
Descriptor: (2R,3R,4R,5S)-1-{[4-({4-[(2R,6S)-2,6-dimethylmorpholin-4-yl]-2-nitroanilino}methyl)phenyl]methyl}-2-(hydroxymethyl)piperidine-3,4,5-triol, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chaetomium alpha glucosidase, ...
Authors:Karade, S.S, Mariuzza, R.A.
Deposit date:2021-07-09
Release date:2023-02-22
Last modified:2023-03-01
Method:X-RAY DIFFRACTION (2.61 Å)
Cite:Structure-Based Design of Potent Iminosugar Inhibitors of Endoplasmic Reticulum alpha-Glucosidase I with Anti-SARS-CoV-2 Activity.
J.Med.Chem., 66, 2023
6X9X
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Crystal structure of Fab fragment of Anti-HCV E2 antibody (HC84.26)
Descriptor: 1,2-ETHANEDIOL, ACETATE ION, HC84.26 Fab Heavy Chain, ...
Authors:Shahid, S, Mariuzza, R.A.
Deposit date:2020-06-03
Release date:2020-12-02
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal Structure of a Bivalent Antibody Fab Fragment.
J.Mol.Biol., 433, 2020
3OWE
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BU of 3owe by Molmil
Crystal Structure of Staphylococcal Enterotoxin G (SEG) in Complex with a High Affinity Mutant Mouse T-cell Receptor Chain
Descriptor: Beta-chain, Enterotoxin SEG
Authors:Fernandez, M.M, Cho, S, Robinson, H, Mariuzza, R.A, Malchiodi, M.L.
Deposit date:2010-09-17
Release date:2010-11-03
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Crystal structure of staphylococcal enterotoxin G (SEG) in complex with a mouse T-cell receptor {beta} chain.
J.Biol.Chem., 286, 2011
7T8V
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BU of 7t8v by Molmil
Co-crystal structure of Chaetomium glucosidase I with EB-0159
Descriptor: (1S,2S,3R,4S,5S)-1-(hydroxymethyl)-5-[(6-{[2-nitro-4-(1H-1,2,3-triazol-1-yl)phenyl]amino}hexyl)amino]cyclohexane-1,2,3,4-tetrol, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Karade, S.S, Mariuzza, R.A.
Deposit date:2021-12-17
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Identification of Endoplasmic Reticulum alpha-Glucosidase I from a Thermophilic Fungus as a Platform for Structure-Guided Antiviral Drug Design.
Biochemistry, 61, 2022
7T66
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Co-crystal structure of Chaetomium glucosidase with compound UV-4
Descriptor: 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, Chaetomium alpha glucosidase, ...
Authors:Karade, S.S, Mariuzza, R.A.
Deposit date:2021-12-13
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.19 Å)
Cite:Identification of Endoplasmic Reticulum alpha-Glucosidase I from a Thermophilic Fungus as a Platform for Structure-Guided Antiviral Drug Design.
Biochemistry, 61, 2022
7T68
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Co-crystal structure of Chaetomium glucosidase with compound UV-5
Descriptor: (2R,3R,4R,5S)-1-[6-(4-azido-2-nitroanilino)hexyl]-2-(hydroxymethyl)piperidine-3,4,5-triol, 2-[BIS-(2-HYDROXY-ETHYL)-AMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, ...
Authors:Karade, S.S, Mariuzza, R.A.
Deposit date:2021-12-13
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.32 Å)
Cite:Identification of Endoplasmic Reticulum alpha-Glucosidase I from a Thermophilic Fungus as a Platform for Structure-Guided Antiviral Drug Design.
Biochemistry, 61, 2022
7T6W
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Crystal structure of Chaetomium Glucosidase I (apo)
Descriptor: 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Chaetomium alpha glucosidase, GLYCEROL, ...
Authors:Karade, S.S, Mariuzza, R.A.
Deposit date:2021-12-14
Release date:2022-05-04
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Identification of Endoplasmic Reticulum alpha-Glucosidase I from a Thermophilic Fungus as a Platform for Structure-Guided Antiviral Drug Design.
Biochemistry, 61, 2022
2IAL
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BU of 2ial by Molmil
Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR
Descriptor: CD4+ T cell receptor E8 alpha chain, CD4+ T cell receptor E8 beta chain
Authors:Deng, L, Langley, R.J, Mariuzza, R.A.
Deposit date:2006-09-08
Release date:2007-04-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (1.92 Å)
Cite:Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Nat.Immunol., 8, 2007
2IAN
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BU of 2ian by Molmil
Structural basis for recognition of mutant self by a tumor-specific, MHC class II-restricted TCR
Descriptor: 15-mer peptide from Triosephosphate isomerase, CD4+ T cell receptor E8 alpha chain, CD4+ T cell receptor E8 beta chain, ...
Authors:Deng, L, Langley, R.J, Mariuzza, R.A.
Deposit date:2006-09-08
Release date:2007-04-03
Last modified:2023-10-25
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Structural basis for the recognition of mutant self by a tumor-specific, MHC class II-restricted T cell receptor
Nat.Immunol., 8, 2007

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