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PDB: 1322 results

5FZQ
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BU of 5fzq by Molmil
Designed TPR Protein M4N
Descriptor: DESIGNED TPR PROTEIN, SULFATE ION
Authors:Albrecht, R, Zhu, H, Hartmann, M.D.
Deposit date:2016-03-15
Release date:2016-10-12
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.148 Å)
Cite:Origin of a folded repeat protein from an intrinsically disordered ancestor.
Elife, 5, 2016
5M8G
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BU of 5m8g by Molmil
Tubulin-MTD265 complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5-(2-morpholin-4-yl-6-pyrrolidin-1-yl-pyrimidin-4-yl)-4-(trifluoromethyl)pyridin-2-amine, CALCIUM ION, ...
Authors:Bohnacker, T, Prota, A.E, Steinmetz, M.O, Wymann, M.P.
Deposit date:2016-10-28
Release date:2017-02-22
Last modified:2024-01-17
Method:X-RAY DIFFRACTION (2.147 Å)
Cite:Deconvolution of Buparlisib's mechanism of action defines specific PI3K and tubulin inhibitors for therapeutic intervention.
Nat Commun, 8, 2017
3ZMP
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BU of 3zmp by Molmil
Src-derived peptide inhibitor complex of PTP1B
Descriptor: PROTO-ONCOGENE TYROSINE-PROTEIN KINASE SRC, TYROSINE-PROTEIN PHOSPHATASE NON-RECEPTOR TYPE 1
Authors:Temmerman, K, Pogenberg, V, Meyer, C, Koehn, M, Wilmanns, M.
Deposit date:2013-02-12
Release date:2014-01-22
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (2.619 Å)
Cite:Development of Accessible Peptidic Tool Compounds to Study the Phosphatase Ptp1B in Intact Cells.
Acs Chem.Biol., 9, 2014
1TMX
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BU of 1tmx by Molmil
Crystal structure of hydroxyquinol 1,2-dioxygenase from Nocardioides Simplex 3E
Descriptor: 1-HEPTADECANOYL-2-TRIDECANOYL-3-GLYCEROL-PHOSPHONYL CHOLINE, BENZOIC ACID, CHLORIDE ION, ...
Authors:Ferraroni, M, Travkin, V.M, Seifert, J, Schlomann, M, Golovleva, L, Scozzafava, A, Briganti, F.
Deposit date:2004-06-11
Release date:2005-03-22
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Crystal structure of the hydroxyquinol 1,2-dioxygenase from Nocardioides simplex 3E, a key enzyme involved in polychlorinated aromatics biodegradation.
J.Biol.Chem., 280, 2005
5LDH
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BU of 5ldh by Molmil
STRUCTURE OF THE ACTIVE TERNARY COMPLEX OF PIG HEART LACTATE DEHYDROGENASE WITH S-LAC-NAD AT 2.7 ANGSTROMS RESOLUTION
Descriptor: (3S)-5-(3-CARBOXY-3-HYDROXYPROPYL) NICOTINAMIDE-ADENINE-DINUCLEOTIDE, CITRIC ACID, LACTATE DEHYDROGENASE
Authors:Grau, U.M, Rossmann, M.G.
Deposit date:1980-10-29
Release date:1981-03-04
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Structure of the active ternary complex of pig heart lactate dehydrogenase with S-lac-NAD at 2.7 A resolution.
J.Mol.Biol., 151, 1981
6SGB
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BU of 6sgb by Molmil
mt-SSU assemblosome of Trypanosoma brucei
Descriptor: 9S rRNA, GUANOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, ...
Authors:Saurer, M, Ramrath, D.J.F, Niemann, M, Calderaro, S, Prange, C, Mattei, S, Scaiola, A, Leitner, A, Bieri, P, Horn, E.K, Leibundgut, M, Boehringer, D, Schneider, A, Ban, N.
Deposit date:2019-08-03
Release date:2019-09-25
Method:ELECTRON MICROSCOPY (3.3 Å)
Cite:Mitoribosomal small subunit biogenesis in trypanosomes involves an extensive assembly machinery.
Science, 365, 2019
3ZL4
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BU of 3zl4 by Molmil
Antibody structural organization: Role of kappa - lambda chain constant domain switch in catalytic functionality
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, A17 ANTIBODY FAB FRAGMENT HEAVY CHAIN, A17 ANTIBODY FAB FRAGMENT LAMBDA LIGHT CHAIN
Authors:Chatziefthimiou, S.D, Ponomarenko, N.A, Kurkova, I.N, Smirnov, A.V, Smirnov, I.V, Lamzin, V.S, Gabibov, A.G, Wilmanns, M.
Deposit date:2013-01-28
Release date:2014-02-05
Last modified:2023-12-20
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Role of Kappa>Lambda Light-Chain Constant-Domain Switch in the Structure and Functionality of A17 Reactibody
Acta Crystallogr.,Sect.D, 70, 2014
7OBJ
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BU of 7obj by Molmil
Carbon regulatory PII-like protein SbtB from Synechocystis sp. 6803 in complex with cyclic di-AMP (c-di-AMP)
Descriptor: (2R,3R,3aS,5R,7aR,9R,10R,10aS,12R,14aR)-2,9-bis(6-amino-9H-purin-9-yl)octahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8 ]tetraoxadiphosphacyclododecine-3,5,10,12-tetrol 5,12-dioxide, Membrane-associated protein slr1513
Authors:Selim, K.A, Albrecht, R, Hartmann, M.D.
Deposit date:2021-04-22
Release date:2022-02-02
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (2 Å)
Cite:Diurnal metabolic control in cyanobacteria requires perception of second messenger signaling molecule c-di-AMP by the carbon control protein SbtB.
Sci Adv, 7, 2021
1TKI
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BU of 1tki by Molmil
AUTOINHIBITED SERINE KINASE DOMAIN OF THE GIANT MUSCLE PROTEIN TITIN
Descriptor: TITIN
Authors:Mayans, M.O, Gautel, M, Wilmanns, M.
Deposit date:1998-05-29
Release date:1999-06-08
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (2 Å)
Cite:Structural basis for activation of the titin kinase domain during myofibrillogenesis.
Nature, 395, 1998
6YXX
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BU of 6yxx by Molmil
State A of the Trypanosoma brucei mitoribosomal large subunit assembly intermediate
Descriptor: 12S ribosomal RNA, 50S ribosomal protein L13, putative, ...
Authors:Jaskolowski, M, Ramrath, D.J.F, Bieri, P, Niemann, M, Mattei, S, Calderaro, S, Leibundgut, M.A, Horn, E.K, Boehringer, D, Schneider, A, Ban, N.
Deposit date:2020-05-04
Release date:2020-10-14
Method:ELECTRON MICROSCOPY (3.9 Å)
Cite:Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis.
Mol.Cell, 79, 2020
6YXY
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BU of 6yxy by Molmil
State B of the Trypanosoma brucei mitoribosomal large subunit assembly intermediate
Descriptor: 12S ribosomal RNA, ADENOSINE-5'-TRIPHOSPHATE, GUANOSINE-5'-TRIPHOSPHATE, ...
Authors:Jaskolowski, M, Ramrath, D.J.F, Bieri, P, Niemann, M, Mattei, S, Calderaro, S, Leibundgut, M.A, Horn, E.K, Boehringer, D, Schneider, A, Ban, N.
Deposit date:2020-05-04
Release date:2020-10-14
Method:ELECTRON MICROSCOPY (3.1 Å)
Cite:Structural Insights into the Mechanism of Mitoribosomal Large Subunit Biogenesis.
Mol.Cell, 79, 2020
8AOP
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BU of 8aop by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 14r
Descriptor: (3S)-3-[(3-aminophenyl)sulfanylmethyl]piperidine-2,6-dione, Cereblon isoform 4, PHOSPHATE ION, ...
Authors:Maiwald, S, Heim, C, Hartmann, M.D.
Deposit date:2022-08-08
Release date:2023-01-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.944 Å)
Cite:Synthesis of novel glutarimide ligands for the E3 ligase substrate receptor Cereblon (CRBN): Investigation of their binding mode and antiproliferative effects against myeloma cell lines.
Eur.J.Med.Chem., 246, 2023
8B2W
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BU of 8b2w by Molmil
Millisecond cryo-trapping by the spitrobot crystal plunger, CTX-M-14 E166A, Ampicillin, 500 MS
Descriptor: (2R,4S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Beta-lactamase
Authors:Mehrabi, P, Sung, S, von Stetten, D, Prester, A, Hatton, C.E, Kleine-Doepke, S, Berkes, A, Gore, G, Leimkohl, J.P, Schikora, H, Kollewe, M, Rohde, H, Wilmanns, M, Tellkamp, F, Schulz, E.C.
Deposit date:2022-09-14
Release date:2023-05-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.78 Å)
Cite:Millisecond cryo-trapping by the spitrobot crystal plunger simplifies time-resolved crystallography.
Nat Commun, 14, 2023
8B2O
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BU of 8b2o by Molmil
Millisecond cryo-trapping by the spitrobot crystal plunger, CTX-M-14 E166A, Ampicillin, 5 sec
Descriptor: (2R,4S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Beta-lactamase
Authors:Mehrabi, P, Sung, S, von Stetten, D, Prester, A, Hatton, C.E, Kleine-Doepke, S, Berkes, A, Gore, G, Leimkohl, J.P, Schikora, H, Kollewe, M, Rohde, H, Wilmanns, M, Tellkamp, F, Schulz, E.C.
Deposit date:2022-09-14
Release date:2023-05-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.86 Å)
Cite:Millisecond cryo-trapping by the spitrobot crystal plunger simplifies time-resolved crystallography.
Nat Commun, 14, 2023
6YEL
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BU of 6yel by Molmil
Stromal interaction molecule 1 coiled-coil 1 fragment
Descriptor: Stromal interaction molecule 1
Authors:Rathner, P, Cerofolini, L, Ravera, E, Bechmann, M, Grabmayr, H, Fahrner, M, Fragai, M, Romanin, C, Luchinat, C, Mueller, N.
Deposit date:2020-03-25
Release date:2020-09-02
Last modified:2024-06-19
Method:SOLUTION NMR
Cite:Interhelical interactions within the STIM1 CC1 domain modulate CRAC channel activation.
Nat.Chem.Biol., 17, 2021
8B2V
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BU of 8b2v by Molmil
Millisecond cryo-trapping by the spitrobot crystal plunger, CTX-M-14 E166A Ampicillin, 1 sec
Descriptor: (2R,4S)-2-[(1R)-1-{[(2R)-2-amino-2-phenylacetyl]amino}-2-oxoethyl]-5,5-dimethyl-1,3-thiazolidine-4-carboxylic acid, Beta-lactamase
Authors:Mehrabi, P, Sung, S, von Stetten, D, Prester, A, Hatton, C.E, Kleine-Doepke, S, Berkes, A, Gore, G, Leimkohl, J.P, Schikora, H, Kollewe, M, Rohde, H, Wilmanns, M, Tellkamp, F, Schulz, E.C.
Deposit date:2022-09-14
Release date:2023-05-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.73 Å)
Cite:Millisecond cryo-trapping by the spitrobot crystal plunger simplifies time-resolved crystallography.
Nat Commun, 14, 2023
6ST5
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BU of 6st5 by Molmil
crystal structure of LicM2
Descriptor: GLYCEROL, LicM2, MAGNESIUM ION, ...
Authors:Gonsior, M, Mainz, A, Hugelland, M, Kuthning, A, Tietzmann, M, Dobbek, H, Martins, B.M, Sussmuth, R.
Deposit date:2019-09-10
Release date:2022-08-10
Method:X-RAY DIFFRACTION (2.82 Å)
Cite:crystal structure of LicM2
To Be Published
5UHY
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BU of 5uhy by Molmil
A Human Antibody Against Zika Virus Crosslinks the E Protein to Prevent Infection
Descriptor: ZV67 Fab chain 1, ZV67 Fab chain 2, envelope protein
Authors:Hasan, S.S, Miller, A, Sapparapu, G, Fernandez, E, Klose, T, Long, F, Fokine, A, Porta, J.C, Jiang, W, Diamond, M.S, Crowe Jr, J.E, Kuhn, R.J, Rossmann, M.G.
Deposit date:2017-01-12
Release date:2017-03-29
Last modified:2019-11-27
Method:ELECTRON MICROSCOPY (6.2 Å)
Cite:A human antibody against Zika virus crosslinks the E protein to prevent infection.
Nat Commun, 8, 2017
2IDF
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BU of 2idf by Molmil
P. aeruginosa azurin N42C/M64E double mutant, BMME-linked dimer
Descriptor: 1-[PYRROL-1-YL-2,5-DIONE-METHOXYMETHYL]-PYRROLE-2,5-DIONE, Azurin, COPPER (II) ION, ...
Authors:Einsle, O, de Jongh, T.E, Hoffmann, M, Cavazzini, D, Rossi, G.L, Ubbink, M, Canters, G.W.
Deposit date:2006-09-15
Release date:2008-03-18
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Electron transfer in a crosslinked protein dimer mediated by a hydrogen-bonded network across the dimer interface
To be Published
3EPD
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BU of 3epd by Molmil
CryoEM structure of poliovirus receptor bound to poliovirus type 3
Descriptor: MYRISTIC ACID, Poliovirus Type3 peptide, Poliovirus receptor, ...
Authors:Zhang, P, Mueller, S, Morais, M.C, Bator, C.M, Bowman, V.D, Hafenstein, S, Wimmer, E, Rossmann, M.G.
Deposit date:2008-09-29
Release date:2008-11-11
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Crystal structure of CD155 and electron microscopic studies of its complexes with polioviruses.
Proc.Natl.Acad.Sci.USA, 105, 2008
3EPC
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BU of 3epc by Molmil
CryoEM structure of poliovirus receptor bound to poliovirus type 1
Descriptor: MYRISTIC ACID, Poliovirus receptor, Protein VP1, ...
Authors:Zhang, P, Mueller, S, Morais, M.C, Bator, C.M, Bowman, V.D, Hafenstein, S, Wimmer, E, Rossmann, M.G.
Deposit date:2008-09-29
Release date:2008-11-11
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (8 Å)
Cite:Crystal structure of CD155 and electron microscopic studies of its complexes with polioviruses.
Proc.Natl.Acad.Sci.USA, 105, 2008
3EPF
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BU of 3epf by Molmil
CryoEM structure of poliovirus receptor bound to poliovirus type 2
Descriptor: 1[2-CHLORO-4-METHOXY-PHENYL-OXYMETHYL]-4-[2,6-DICHLORO-PHENYL-OXYMETHYL]-BENZENE, MYRISTIC ACID, Poliovirus receptor, ...
Authors:Zhang, P, Mueller, S, Morais, M.C, Bator, C.M, Bowman, V.D, Hafenstein, S, Wimmer, E, Rossmann, M.G.
Deposit date:2008-09-29
Release date:2008-11-11
Last modified:2024-04-17
Method:ELECTRON MICROSCOPY (9 Å)
Cite:Crystal structure of CD155 and electron microscopic studies of its complexes with polioviruses.
Proc.Natl.Acad.Sci.USA, 105, 2008
1JQQ
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BU of 1jqq by Molmil
Crystal structure of Pex13p(301-386) SH3 domain
Descriptor: PEROXISOMAL MEMBRANE PROTEIN PAS20
Authors:Douangamath, A, Mayans, O, Barnett, P, Distel, B, Wilmanns, M.
Deposit date:2001-08-08
Release date:2002-12-06
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Topography for Independent Binding of alpha-Helical and PPII-Helical Ligands to a Peroxisomal SH3 Domain
Mol.Cell, 10, 2002
8B3M
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BU of 8b3m by Molmil
Millisecond cryo-trapping by the spitrobot crystal plunger, CTXM-14 Avibactam complex, SSX, 1 sec
Descriptor: (2S,5R)-1-formyl-5-[(sulfooxy)amino]piperidine-2-carboxamide, Beta-lactamase
Authors:Mehrabi, P, Sung, S, von Stetten, D, Prester, A, Hatton, C.E, Kleine-Doepke, S, Berkes, A, Gore, G, Leimkohl, J.P, Schikora, H, Kollewe, M, Rohde, H, Wilmanns, M, Tellkamp, F, Schulz, E.C.
Deposit date:2022-09-16
Release date:2023-05-24
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.97 Å)
Cite:Millisecond cryo-trapping by the spitrobot crystal plunger simplifies time-resolved crystallography.
Nat Commun, 14, 2023
8AOQ
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BU of 8aoq by Molmil
Cereblon isoform 4 from Magnetospirillum gryphiswaldense in complex with compound 20a
Descriptor: (3~{S})-3-(phenylsulfonylmethyl)piperidine-2,6-dione, Cereblon isoform 4, ZINC ION
Authors:Maiwald, S, Heim, C, Hartmann, M.D.
Deposit date:2022-08-08
Release date:2023-01-11
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.088 Å)
Cite:Synthesis of novel glutarimide ligands for the E3 ligase substrate receptor Cereblon (CRBN): Investigation of their binding mode and antiproliferative effects against myeloma cell lines.
Eur.J.Med.Chem., 246, 2023

221716

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