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PDB: 287 件

5NG1
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TUBULIN-MTC-zampanolide complex
分子名称: (2Z,4E)-N-[(S)-[(1S,2E,5S,8E,10Z,17S)-3,11-dimethyl-19-methylidene-7,13-dioxo-6,21-dioxabicyclo[15.3.1]henicosa-2,8,10-trien-5-yl](hydroxy)methyl]hexa-2,4-dienamide, (2~{Z},4~{E})-~{N}-[(~{S})-oxidanyl-[(1~{S},2~{E},5~{S},11~{R},17~{S},19~{R})-3,11,19-trimethyl-7,13-bis(oxidanylidene)-6,21-dioxabicyclo[15.3.1]henicos-2-en-5-yl]methyl]hexa-2,4-dienamide, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ...
著者Field, J.J, Pera, B, Estevez Gallego, J, Calvo, E, Rodriguez-Salarichs, J, Saez-Calvo, G, Zuwerra, D, Jordi, M, Prota, A.E, Menchon, G, Miller, J.H, Altmann, K.-H, Diaz, J.F.
登録日2017-03-16
公開日2017-10-25
最終更新日2024-01-17
実験手法X-RAY DIFFRACTION (2.2 Å)
主引用文献Zampanolide Binding to Tubulin Indicates Cross-Talk of Taxane Site with Colchicine and Nucleotide Sites.
J. Nat. Prod., 81, 2018
2VHF
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Structure of the CYLD USP domain
分子名称: UBIQUITIN CARBOXYL-TERMINAL HYDROLASE CYLD, ZINC ION
著者Komander, D, Lord, C.J, Scheel, H, Swift, S, Hofmann, K, Ashworth, A, Barford, D.
登録日2007-11-21
公開日2008-03-11
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (2.8 Å)
主引用文献The Structure of the Cyld Usp Domain Explains its Specificity for Lys63-Linked Polyubiquitin and Reveals a B-Box Module
Mol.Cell.Biol., 29, 2008
4BUO
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High Resolution Structure of Thermostable Agonist-bound Neurotensin Receptor 1 Mutant without Lysozyme Fusion
分子名称: GLYCINE, NEUROTENSIN RECEPTOR TYPE 1, NEUROTENSIN/NEUROMEDIN N
著者Egloff, P, Hillenbrand, M, Schlinkmann, K.M, Batyuk, A, Mittl, P, Plueckthun, A.
登録日2013-06-21
公開日2014-01-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (2.75 Å)
主引用文献Structure of Signaling-Competent Neurotensin Receptor 1 Obtained by Directed Evolution in Escherichia Coli
Proc.Natl.Acad.Sci.USA, 111, 2014
6TJ8
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Escherichia coli transketolase in complex with cofactor analog 2'-methoxythiamine diphosphate
分子名称: 1,2-ETHANEDIOL, 2-[3-[(4-azanyl-2-methoxy-pyrimidin-5-yl)methyl]-4-methyl-1,3-thiazol-5-yl]ethyl phosphono hydrogen phosphate, CALCIUM ION, ...
著者Rabe von Pappenheim, F, Tittmann, K.
登録日2019-11-25
公開日2020-07-08
最終更新日2024-01-24
実験手法X-RAY DIFFRACTION (0.921 Å)
主引用文献Structural basis for antibiotic action of the B 1 antivitamin 2'-methoxy-thiamine.
Nat.Chem.Biol., 16, 2020
8WA9
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Human transketolase soaked with donor ketose D-fructose
分子名称: 1,2-ETHANEDIOL, 2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE, CALCIUM ION, ...
著者Liu, Z, Tittmann, K, Dai, S.
登録日2023-09-07
公開日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Multifaceted Role of the Substrate Phosphate Group in Transketolase Catalysis
Acs Catalysis, 14, 2024
8WA7
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E.coli transketolase soaked with donor ketose D-fructose
分子名称: 1,2-ETHANEDIOL, 2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE, GLYCEROL, ...
著者Liu, Z, Dai, S, Tittmann, K.
登録日2023-09-07
公開日2024-01-24
実験手法X-RAY DIFFRACTION (1.63 Å)
主引用文献Multifaceted Role of the Substrate Phosphate Group in Transketolase Catalysis
Acs Catalysis, 14, 2024
8WAA
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Human transketolase soaked with donor ketose D-xylulose
分子名称: 1,2-ETHANEDIOL, 2-[3-[(4-AMINO-2-METHYL-5-PYRIMIDINYL)METHYL]-2-(1,2-DIHYDROXYETHYL)-4-METHYL-1,3-THIAZOL-3-IUM-5-YL]ETHYL TRIHYDROGEN DIPHOSPHATE, CALCIUM ION, ...
著者Liu, Z, Dai, S, Tittmann, K.
登録日2023-09-07
公開日2024-01-24
実験手法X-RAY DIFFRACTION (1.5 Å)
主引用文献Multifaceted Role of the Substrate Phosphate Group in Transketolase Catalysis
Acs Catalysis, 14, 2024
6FFL
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Maltose/maltodextrin-binding domain MalE from Bdellovibrio bacteriovorus bound to maltotriose
分子名称: Maltose/maltodextrin transport permease homologue, PLATINUM (II) ION, SULFATE ION, ...
著者Licht, A, Werther, T, Bommer, M, Neumann, K, Schneider, E.
登録日2018-01-08
公開日2018-01-24
最終更新日2024-05-08
実験手法X-RAY DIFFRACTION (1.707 Å)
主引用文献Structural and functional characterization of a maltose/maltodextrin ABC transporter comprising a single solute binding domain (MalE) fused to the transmembrane subunit MalF.
Res. Microbiol., 170, 2018
6H60
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pseudo-atomic structural model of the E3BP component of the human pyruvate dehydrogenase multienzyme complex
分子名称: Pyruvate dehydrogenase protein X component, mitochondrial
著者Haselbach, D, Prajapati, S, Tittmann, K, Stark, H.
登録日2018-07-25
公開日2019-06-05
最終更新日2024-05-15
実験手法ELECTRON MICROSCOPY (6 Å)
主引用文献Structural and Functional Analyses of the Human PDH Complex Suggest a "Division-of-Labor" Mechanism by Local E1 and E3 Clusters.
Structure, 27, 2019
4BV0
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High Resolution Structure of Evolved Agonist-bound Neurotensin Receptor 1 Mutant without Lysozyme Fusion
分子名称: NEUROTENSIN RECEPTOR TYPE 1, NEUROTENSIN/NEUROMEDIN N
著者Egloff, P, Hillenbrand, M, Scott, D.J, Schlinkmann, K.M, Heine, P, Balada, S, Batyuk, A, Mittl, P, Schuetz, M, Plueckthun, A.
登録日2013-06-24
公開日2014-01-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.1 Å)
主引用文献Structure of Signaling-Competent Neurotensin Receptor 1 Obtained by Directed Evolution in Escherichia Coli
Proc.Natl.Acad.Sci.USA, 111, 2014
4BWB
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Structure of Evolved Agonist-bound Neurotensin Receptor 1 Mutant without Lysozyme Fusion
分子名称: NEUROTENSIN, NEUROTENSIN RECEPTOR TYPE 1
著者Egloff, P, Hillenbrand, M, Scott, D.J, Schlinkmann, K.M, Heine, P, Balada, S, Batyuk, A, Mittl, P, Plueckthun, A.
登録日2013-07-01
公開日2014-01-29
最終更新日2023-12-20
実験手法X-RAY DIFFRACTION (3.57 Å)
主引用文献Structure of Signaling-Competent Neurotensin Receptor 1 Obtained by Directed Evolution in Escherichia Coli
Proc.Natl.Acad.Sci.USA, 111, 2014
8WA8
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Human transketolase in complex with phosphite
分子名称: 1,2-ETHANEDIOL, CALCIUM ION, PHOSPHITE ION, ...
著者Liu, Z, Tittmann, K, Dai, S.
登録日2023-09-07
公開日2024-01-24
実験手法X-RAY DIFFRACTION (1.48 Å)
主引用文献Multifaceted Role of the Substrate Phosphate Group in Transketolase Catalysis
Acs Catalysis, 14, 2024

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