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PDB: 5 results
9C7A
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BU of 9c7a by Molmil
Crystal structure of R149W neurodevelopmental disease-associated U2AF2 variant
Descriptor: DNA/RNA (5'-R(P*UP*U)-D(P*U)-R(P*UP*U)-D(P*(BRU))-R(P*CP*C)-3'), GLYCEROL, SODIUM ION, ...
Authors:Maji, D, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2024-06-10
Release date:2024-10-02
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Recurrent neurodevelopmentally-associated variants of the pre-mRNA splicing factor U2AF2 alter RNA binding affinities and interactions
To Be Published
9C7B
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BU of 9c7b by Molmil
Crystal structure of R150H neurodevelopmental disease-associated U2AF2 variant
Descriptor: DNA/RNA (5'-R(P*UP*U)-D(P*U)-R(P*UP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit
Authors:Maji, D, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2024-06-10
Release date:2024-10-02
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Recurrent neurodevelopmentally-associated variants of the pre-mRNA splicing factor U2AF2 alter RNA binding affinities and interactions
To Be Published
6XLV
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BU of 6xlv by Molmil
Crystal structure of leukemia-associated N196K mutant of U2AF65 bound to AdML splice site
Descriptor: DNA/RNA (5'-R(P*UP*UP*(UD)P*UP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit
Authors:Maji, D, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2020-06-29
Release date:2020-10-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing.
J.Biol.Chem., 295, 2020
6XLW
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BU of 6xlw by Molmil
Crystal structure of U2AF65 bound to AdML splice site sequence
Descriptor: DI(HYDROXYETHYL)ETHER, DNA/RNA (5'-R(P*UP*UP*(UD)P*UP*U)-D(P*(BRU))-R(P*CP*C)-3'), GLYCEROL, ...
Authors:Maji, D, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2020-06-29
Release date:2020-10-07
Last modified:2024-05-22
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing.
J.Biol.Chem., 295, 2020
6XLX
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BU of 6xlx by Molmil
Crystal structure of cancer-associated G301D mutant of U2AF65 bound to AdML splice site
Descriptor: DNA/RNA (5'-R(P*UP*UP*(UD)P*UP*U)-D(P*(BRU))-R(P*CP*C)-3'), Splicing factor U2AF 65 kDa subunit
Authors:Maji, D, Jenkins, J.L, Kielkopf, C.L.
Deposit date:2020-06-29
Release date:2020-10-07
Last modified:2023-10-18
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Representative cancer-associated U2AF2 mutations alter RNA interactions and splicing.
J.Biol.Chem., 295, 2020

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數據於2024-10-09公開中

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