6IKA
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![BU of 6ika by Molmil](/molmil-images/mine/6ika) | HIV-1 reverse transcriptase with Q151M/G112S/D113A/Y115F/F116Y/F160L/I159L:DNA:entecavir-triphosphate ternary complex | Descriptor: | DNA/RNA (38-MER), GLYCEROL, HIV-1 RT p51 subunit, ... | Authors: | Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. | Deposit date: | 2018-10-15 | Release date: | 2019-01-30 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.598 Å) | Cite: | Active-site deformation in the structure of HIV-1 RT with HBV-associated septuple amino acid substitutions rationalizes the differential susceptibility of HIV-1 and HBV against 4'-modified nucleoside RT inhibitors. Biochem. Biophys. Res. Commun., 509, 2019
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6KDK
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![BU of 6kdk by Molmil](/molmil-images/mine/6kdk) | HIV-1 reverse transcriptase with Q151M/Y115F/F116Y:DNA:dCTP ternary complex | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ... | Authors: | Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. | Deposit date: | 2019-07-02 | Release date: | 2020-03-04 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.56 Å) | Cite: | Structural features in common of HBV and HIV-1 resistance against chirally-distinct nucleoside analogues entecavir and lamivudine. Sci Rep, 10, 2020
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5XN0
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![BU of 5xn0 by Molmil](/molmil-images/mine/5xn0) | HIV-1 reverse transcriptase Q151M:DNA binary complex | Descriptor: | 38-MER DNA aptamer, GLYCEROL, Pol protein, ... | Authors: | Yasutake, Y, Tamura, N, Hayashi, H, Maeda, K. | Deposit date: | 2017-05-17 | Release date: | 2018-02-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.596 Å) | Cite: | HIV-1 with HBV-associated Q151M substitution in RT becomes highly susceptible to entecavir: structural insights into HBV-RT inhibition by entecavir. Sci Rep, 8, 2018
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5XN1
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![BU of 5xn1 by Molmil](/molmil-images/mine/5xn1) | HIV-1 reverse transcriptase Q151M:DNA:entecavir-triphosphate ternary complex | Descriptor: | 38-MER DNA aptamer, GLYCEROL, MAGNESIUM ION, ... | Authors: | Yasutake, Y, Tamura, N, Hayashi, H, Maeda, K. | Deposit date: | 2017-05-17 | Release date: | 2018-02-07 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.446 Å) | Cite: | HIV-1 with HBV-associated Q151M substitution in RT becomes highly susceptible to entecavir: structural insights into HBV-RT inhibition by entecavir. Sci Rep, 8, 2018
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2ZGY
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![BU of 2zgy by Molmil](/molmil-images/mine/2zgy) | PARM with GDP | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Plasmid segregation protein parM | Authors: | Popp, D, Narita, A, Oda, T, Fujisawa, T, Matsuo, H, Nitanai, Y, Iwasa, M, Maeda, K, Onishi, H, Maeda, Y. | Deposit date: | 2008-01-30 | Release date: | 2008-02-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Molecular structure of the ParM polymer and the mechanism leading to its nucleotide-driven dynamic instability Embo J., 27, 2008
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2ZGZ
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![BU of 2zgz by Molmil](/molmil-images/mine/2zgz) | PARM with GMPPNP | Descriptor: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-GUANYLATE ESTER, Plasmid segregation protein parM | Authors: | Popp, D, Narita, A, Oda, T, Fujisawa, T, Matsuo, H, Nitanai, Y, Iwasa, M, Maeda, K, Onishi, H, Maeda, Y. | Deposit date: | 2008-01-30 | Release date: | 2008-02-12 | Last modified: | 2023-11-01 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Molecular structure of the ParM polymer and the mechanism leading to its nucleotide-driven dynamic instability Embo J., 27, 2008
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7DBN
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![BU of 7dbn by Molmil](/molmil-images/mine/7dbn) | HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/M184V/F160M:DNA:dCTP ternary complex | Descriptor: | 2'-DEOXYCYTIDINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ... | Authors: | Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. | Deposit date: | 2020-10-21 | Release date: | 2021-08-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.67 Å) | Cite: | Biochemical and Structural Properties of Entecavir-Resistant Hepatitis B Virus Polymerase with L180M/M204V Mutations. J.Virol., 95, 2021
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7DBM
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![BU of 7dbm by Molmil](/molmil-images/mine/7dbm) | HIV-1 reverse transcriptase mutant Q151M/Y115F/F116Y/M184V:DNA:dGTP ternary complex | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA/RNA (38-MER), GLYCEROL, ... | Authors: | Yasutake, Y, Hattori, S.I, Tamura, N, Maeda, K. | Deposit date: | 2020-10-21 | Release date: | 2021-08-04 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (2.43 Å) | Cite: | Biochemical and Structural Properties of Entecavir-Resistant Hepatitis B Virus Polymerase with L180M/M204V Mutations. J.Virol., 95, 2021
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4A6K
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![BU of 4a6k by Molmil](/molmil-images/mine/4a6k) | Crystal structure of Slm1-PH domain in complex with D-myo-Inositol-4- phosphate | Descriptor: | D-MYO-INOSITOL-4-PHOSPHATE, PHOSPHATE ION, PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE-BINDING PROTEIN SLM1 | Authors: | Anand, K, Maeda, K, Gavin, A.C. | Deposit date: | 2011-11-04 | Release date: | 2012-06-13 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Structural Analyses of Slm1-Ph Domain Demonstrate Ligand Binding in the Non-Canonical Site Plos One, 7, 2012
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4A6H
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![BU of 4a6h by Molmil](/molmil-images/mine/4a6h) | Crystal structure of Slm1-PH domain in complex with Inositol-4- phosphate | Descriptor: | D-MYO-INOSITOL-4-PHOSPHATE, PHOSPHATE ION, PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE-BINDING PROTEIN SLM1 | Authors: | Anand, K, Maeda, K, Gavin, A.C. | Deposit date: | 2011-11-03 | Release date: | 2012-06-13 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (1.449 Å) | Cite: | Structural Analyses of Slm1-Ph Domain Demonstrate Ligand Binding in the Non-Canonical Site Plos One, 7, 2012
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4A6F
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![BU of 4a6f by Molmil](/molmil-images/mine/4a6f) | Crystal structure of Slm1-PH domain in complex with Phosphoserine | Descriptor: | PHOSPHATE ION, PHOSPHATIDYLINOSITOL 4,5-BISPHOSPHATE-BINDING PROTEIN SLM1, PHOSPHOSERINE | Authors: | Anand, K, Maeda, K, Gavin, A.C. | Deposit date: | 2011-11-02 | Release date: | 2012-06-13 | Last modified: | 2023-12-20 | Method: | X-RAY DIFFRACTION (1.68 Å) | Cite: | Structural Analyses of Slm1-Ph Domain Demonstrate Ligand Binding in the Non-Canonical Site Plos One, 7, 2012
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2ZHC
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![BU of 2zhc by Molmil](/molmil-images/mine/2zhc) | ParM filament | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, Plasmid segregation protein parM | Authors: | Popp, D, Narita, A, Oda, T, Fujisawa, T, Matsuo, H, Nitanai, Y, Iwasa, M, Maeda, K, Onishi, H, Maeda, Y. | Deposit date: | 2008-02-04 | Release date: | 2008-02-26 | Last modified: | 2024-03-13 | Method: | ELECTRON MICROSCOPY (23 Å) | Cite: | Molecular structure of the ParM polymer and the mechanism leading to its nucleotide-driven dynamic instability Embo J., 27, 2008
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