8SVD
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6UEP
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6DXO
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![BU of 6dxo by Molmil](/molmil-images/mine/6dxo) | 1.8 A structure of RsbN-BldN complex. | Descriptor: | BldN, RNA polymerase ECF-subfamily sigma factor | Authors: | Schumacher, M.A. | Deposit date: | 2018-06-29 | Release date: | 2018-07-11 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The crystal structure of the RsbN-sigma BldN complex from Streptomyces venezuelae defines a new structural class of anti-sigma factor. Nucleic Acids Res., 46, 2018
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6UEO
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![BU of 6ueo by Molmil](/molmil-images/mine/6ueo) | Structure of A. thaliana TBP-AC mismatch DNA site | Descriptor: | DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*AP*AP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*CP*TP*TP*TP*AP*TP*AP*GP*C)-3'), TATA-box-binding protein 1 | Authors: | Schumacher, M.A. | Deposit date: | 2019-09-22 | Release date: | 2020-09-02 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | DNA mismatches reveal conformational penalties in protein-DNA recognition. Nature, 587, 2020
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6UER
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6UEQ
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![BU of 6ueq by Molmil](/molmil-images/mine/6ueq) | Structure of TBP bound to C-C mismatch containing TATA site | Descriptor: | DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*AP*AP*CP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*TP*TP*TP*TP*AP*TP*AP*GP*C)-3'), SULFATE ION, ... | Authors: | Schumacher, M.A, Al-Hashimi, H. | Deposit date: | 2019-09-22 | Release date: | 2020-09-02 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | DNA mismatches reveal conformational penalties in protein-DNA recognition. Nature, 587, 2020
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6NJQ
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![BU of 6njq by Molmil](/molmil-images/mine/6njq) | Structure of TBP-Hoogsteen containing DNA complex | Descriptor: | DNA (5'-D(*GP*CP*TP*AP*TP*AP*AP*AP*CP*GP*GP*GP*CP*A)-3'), DNA (5'-D(*TP*GP*CP*CP*CP*GP*TP*TP*TP*AP*TP*AP*GP*C)-3'), TATA-box-binding protein 1 | Authors: | Schumacher, M.A, Stelling, A. | Deposit date: | 2019-01-04 | Release date: | 2019-10-30 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.75 Å) | Cite: | Infrared Spectroscopic Observation of a G-C+Hoogsteen Base Pair in the DNA:TATA-Box Binding Protein Complex Under Solution Conditions. Angew.Chem.Int.Ed.Engl., 58, 2019
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6NON
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![BU of 6non by Molmil](/molmil-images/mine/6non) | Structure of Cyanthece apo McdA | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Cobyrinic acid ac-diamide synthase, MAGNESIUM ION | Authors: | Schumacher, M.A. | Deposit date: | 2019-01-16 | Release date: | 2019-04-24 | Last modified: | 2019-06-26 | Method: | X-RAY DIFFRACTION (2.68 Å) | Cite: | Structures of maintenance of carboxysome distribution Walker-box McdA and McdB adaptor homologs. Nucleic Acids Res., 47, 2019
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7U3D
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![BU of 7u3d by Molmil](/molmil-images/mine/7u3d) | Structure of S. venezuelae GlgX-c-di-GMP-acarbose complex (4.6) | Descriptor: | 4,6-dideoxy-4-{[(1S,4R,5S,6S)-4,5,6-trihydroxy-3-(hydroxymethyl)cyclohex-2-en-1-yl]amino}-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose-(1-4)-alpha-D-glucopyranose, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Glycogen debranching enzyme GlgX | Authors: | Schumacher, M.A. | Deposit date: | 2022-02-27 | Release date: | 2022-10-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Allosteric regulation of glycogen breakdown by the second messenger cyclic di-GMP. Nat Commun, 13, 2022
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7U3B
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![BU of 7u3b by Molmil](/molmil-images/mine/7u3b) | Structure of S. venezuelae GlgX bound to c-di-GMP and acarbose (pH 8.5) | Descriptor: | 4-O-(4,6-dideoxy-4-{[(1S,2S,3S,4R,5S)-2,3,4-trihydroxy-5-(hydroxymethyl)cyclohexyl]amino}-alpha-D-glucopyranosyl)-beta-D-glucopyranose, 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Glycogen debranching enzyme GlgX, ... | Authors: | Schumacher, M.A, Tschowri, N. | Deposit date: | 2022-02-26 | Release date: | 2022-10-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.6 Å) | Cite: | Allosteric regulation of glycogen breakdown by the second messenger cyclic di-GMP. Nat Commun, 13, 2022
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7U39
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7U3A
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![BU of 7u3a by Molmil](/molmil-images/mine/7u3a) | Structure of the Streptomyces venezuelae GlgX-c-di-GMP complex | Descriptor: | 9,9'-[(2R,3R,3aS,5S,7aR,9R,10R,10aS,12S,14aR)-3,5,10,12-tetrahydroxy-5,12-dioxidooctahydro-2H,7H-difuro[3,2-d:3',2'-j][1,3,7,9,2,8]tetraoxadiphosphacyclododecine-2,9-diyl]bis(2-amino-1,9-dihydro-6H-purin-6-one), Glycogen debranching enzyme GlgX | Authors: | Schumacher, M.A. | Deposit date: | 2022-02-26 | Release date: | 2022-10-05 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (3.34 Å) | Cite: | Allosteric regulation of glycogen breakdown by the second messenger cyclic di-GMP. Nat Commun, 13, 2022
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6P5R
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![BU of 6p5r by Molmil](/molmil-images/mine/6p5r) | Structure of T. brucei MERS1-GDP complex | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Mitochondrial edited mRNA stability factor 1 | Authors: | Schumacher, M.A. | Deposit date: | 2019-05-30 | Release date: | 2019-11-06 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | Structures of MERS1, the 5' processing enzyme of mitochondrial mRNAs inTrypanosoma brucei. Rna, 26, 2020
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6CFX
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![BU of 6cfx by Molmil](/molmil-images/mine/6cfx) | Bosea sp GapR solved in the presence of DNA | Descriptor: | PHOSPHATE ION, UPF0335 protein ASE63_04290 | Authors: | Schumacher, M.A. | Deposit date: | 2018-02-18 | Release date: | 2018-09-12 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A Bacterial Chromosome Structuring Protein Binds Overtwisted DNA to Stimulate Type II Topoisomerases and Enable DNA Replication. Cell, 175, 2018
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6AMA
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8DPK
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7TZV
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![BU of 7tzv by Molmil](/molmil-images/mine/7tzv) | Structure of DriD C-domain bound to 9mer ssDNA | Descriptor: | DNA (5'-D(*TP*AP*GP*TP*CP*TP*AP*CP*T)-3'), WYL domain-containing protein | Authors: | Schumacher, M.A, Laub, M. | Deposit date: | 2022-02-16 | Release date: | 2022-06-01 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | ssDNA is an allosteric regulator of the C. crescentus SOS-independent DNA damage response transcription activator, DriD. Genes Dev., 36, 2022
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6E4N
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6E4P
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![BU of 6e4p by Molmil](/molmil-images/mine/6e4p) | Structure of the T. brucei RRM domain in complex with RNA | Descriptor: | RNA (5'-R(P*UP*UP*UP*U)-3'), RNA-binding protein, putative | Authors: | Schumacher, M.A. | Deposit date: | 2018-07-18 | Release date: | 2018-12-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.949 Å) | Cite: | The RRM of the kRNA-editing protein TbRGG2 uses multiple surfaces to bind and remodel RNA. Nucleic Acids Res., 47, 2019
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6U9X
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![BU of 6u9x by Molmil](/molmil-images/mine/6u9x) | Structure of T. brucei MERS1-RNA complex | Descriptor: | Mitochondrial edited mRNA stability factor 1, RNA (5'-R(*GP*AP*GP*AP*GP*GP*GP*GP*GP*UP*U)-3') | Authors: | Schumacher, M.A. | Deposit date: | 2019-09-09 | Release date: | 2019-11-06 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Structures of MERS1, the 5' processing enzyme of mitochondrial mRNAs inTrypanosoma brucei. Rna, 26, 2020
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6AMK
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![BU of 6amk by Molmil](/molmil-images/mine/6amk) | Structure of Streptomyces venezuelae BldC-whiI opt complex | Descriptor: | DNA (5'-D(*AP*AP*TP*GP*TP*CP*CP*GP*AP*AP*TP*TP*AP*CP*CP*CP*GP*AP*AP*TP*TP*G)-3'), DNA (5'-D(*TP*TP*CP*AP*AP*TP*TP*CP*GP*GP*GP*TP*AP*AP*TP*TP*CP*GP*GP*GP*CP*A)-3'), Putative DNA-binding protein | Authors: | Schumacher, M.A. | Deposit date: | 2017-08-09 | Release date: | 2018-03-28 | Last modified: | 2018-11-07 | Method: | X-RAY DIFFRACTION (3.288 Å) | Cite: | The MerR-like protein BldC binds DNA direct repeats as cooperative multimers to regulate Streptomyces development. Nat Commun, 9, 2018
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8TGE
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6BYL
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![BU of 6byl by Molmil](/molmil-images/mine/6byl) | Structure of 14-3-3 gamma bound to O-GlcNAcylated thr peptide | Descriptor: | 14-3-3 protein gamma, 2-acetamido-2-deoxy-beta-D-glucopyranose, TSASTTVPVTTATTTTTSTW O-GlcNac peptide | Authors: | Schumacher, M.A. | Deposit date: | 2017-12-20 | Release date: | 2018-05-09 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (3.35 Å) | Cite: | Structural basis of O-GlcNAc recognition by mammalian 14-3-3 proteins. Proc.Natl.Acad.Sci.USA, 115, 2018
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6E4O
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![BU of 6e4o by Molmil](/molmil-images/mine/6e4o) | Structure of apo T. brucei RRM: P4(1)2(1)2 form | Descriptor: | RNA-binding protein, putative | Authors: | Schumacher, M.A. | Deposit date: | 2018-07-18 | Release date: | 2018-12-12 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | The RRM of the kRNA-editing protein TbRGG2 uses multiple surfaces to bind and remodel RNA. Nucleic Acids Res., 47, 2019
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1UPU
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![BU of 1upu by Molmil](/molmil-images/mine/1upu) | STRUCTURE OF THE URACIL PHOSPHORIBOSYLTRANSFERASE, MUTANT C128V, BOUND TO PRODUCT URIDINE-1-MONOPHOSPHATE (UMP) | Descriptor: | PHOSPHATE ION, URACIL PHOSPHORIBOSYLTRANSFERASE, URIDINE-5'-MONOPHOSPHATE | Authors: | Schumacher, M.A, Carter, D, Scott, D, Roos, D, Ullman, B, Brennan, R.G. | Deposit date: | 1998-04-16 | Release date: | 1999-05-11 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | Crystal structures of Toxoplasma gondii uracil phosphoribosyltransferase reveal the atomic basis of pyrimidine discrimination and prodrug binding. EMBO J., 17, 1998
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