5ENE
| Crystal structure of the second bromodomain of Pleckstrin homology domain interacting protein (PHIP) in complex with 5-Amino-2-benzyl-1,3-oxazole-4-carbonitrile (SGC - Diamond I04-1 fragment screening) | 分子名称: | 5-azanyl-2-(phenylmethyl)-1,3-oxazole-4-carbonitrile, PH-interacting protein | 著者 | Krojer, T, Talon, R, Collins, P, Bradley, A, Cox, O, Amin, J, Szykowska, A, Burgess-Brown, N, Spencer, J, Brennan, P, Bountra, C, Arrowsmith, C.H, Edwards, A, von Delft, F, Structural Genomics Consortium (SGC) | 登録日 | 2015-11-09 | 公開日 | 2016-04-27 | 最終更新日 | 2024-01-10 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | A poised fragment library enables rapid synthetic expansion yielding the first reported inhibitors of PHIP(2), an atypical bromodomain. Chem Sci, 7, 2016
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1KMA
| NMR Structure of the Domain-I of the Kazal-type Thrombin Inhibitor Dipetalin | 分子名称: | DIPETALIN | 著者 | Schlott, B, Wohnert, J, Icke, C, Hartmann, M, Ramachandran, R, Guhrs, K.-H, Glusa, E, Flemming, J, Gorlach, M, Grosse, F, Ohlenschlager, O. | 登録日 | 2001-12-14 | 公開日 | 2002-05-15 | 最終更新日 | 2022-02-23 | 実験手法 | SOLUTION NMR | 主引用文献 | Interaction of Kazal-type inhibitor domains with serine proteinases: biochemical and structural studies. J.Mol.Biol., 318, 2002
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1SQR
| Solution Structure of the 50S Ribosomal Protein L35AE from Pyrococcus furiosus. Northeast Structural Genomics Consortium Target PfR48. | 分子名称: | 50S ribosomal protein L35Ae | 著者 | Snyder, D.A, Aramini, J.M, Huang, Y.J, Xiao, R, Cort, J.R, Shastry, R, Ma, L.C, Liu, J, Rost, B, Acton, T.B, Kennedy, M.A, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2004-03-19 | 公開日 | 2004-11-16 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Structure of the 50S Ribosomal Protein L35AE from Pyrococcus furiosus: Northeast Structural Genomics Consortium Target PfR48 To be Published
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4C2U
| Crystal structure of Deinococcus radiodurans UvrD in complex with DNA, Form 1 | 分子名称: | DNA HELICASE II, FOR25, GLYCEROL, ... | 著者 | Stelter, M, Acajjaoui, S, McSweeney, S, Timmins, J. | 登録日 | 2013-08-20 | 公開日 | 2013-10-30 | 最終更新日 | 2023-12-20 | 実験手法 | X-RAY DIFFRACTION (2.55 Å) | 主引用文献 | Structural and Mechanistic Insight Into DNA Unwinding by Deinococcus Radiodurans Uvrd. Plos One, 8, 2013
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4C2T
| Crystal structure of full length Deinococcus radiodurans UvrD in complex with DNA | 分子名称: | DNA HELICASE II, DNA STRAND FOR28, DNA STRAND REV28, ... | 著者 | Stelter, M, Acajjaoui, S, McSweeney, S, Timmins, J. | 登録日 | 2013-08-20 | 公開日 | 2013-10-30 | 最終更新日 | 2024-05-01 | 実験手法 | X-RAY DIFFRACTION (3.997 Å) | 主引用文献 | Structural and Mechanistic Insight Into DNA Unwinding by Deinococcus Radiodurans Uvrd. Plos One, 8, 2013
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4ABY
| Crystal structure of Deinococcus radiodurans RecN head domain | 分子名称: | DNA REPAIR PROTEIN RECN | 著者 | Pellegrino, S, Radzimanowski, J, de Sanctis, D, McSweeney, S, Timmins, J. | 登録日 | 2011-12-12 | 公開日 | 2012-12-12 | 最終更新日 | 2012-12-26 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural and Functional Characterization of an Smc-Like Protein Recn: New Insights Into Double-Strand Break Repair. Structure, 20, 2012
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2K07
| Solution NMR structure of human E2-like ubiquitin-fold modifier conjugating enzyme 1 (UFC1). Northeast Structural Genomics Consortium target HR41 | 分子名称: | Ufm1-conjugating enzyme 1 | 著者 | Liu, G, Eletsky, A, Atreya, H.S, Aramini, J.M, Xiao, R, Acton, T, Montelione, G.T, Szyperski, T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2008-01-25 | 公開日 | 2008-02-19 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR and X-RAY structures of human E2-like ubiquitin-fold modifier conjugating enzyme 1 (UFC1) reveal structural and functional conservation in the metazoan UFM1-UBA5-UFC1 ubiquination pathway. J.STRUCT.FUNCT.GENOM., 10, 2009
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2K3U
| Structure of the tyrosine-sulfated C5a receptor N-terminus in complex with the immune evasion protein CHIPS. | 分子名称: | C5a anaphylatoxin chemotactic receptor 1, Chemotaxis inhibitory protein | 著者 | Ippel, J.H, Bunschoten, A, Kemmink, J, Liskamp, R. | 登録日 | 2008-05-16 | 公開日 | 2009-03-10 | 最終更新日 | 2023-11-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure of the Tyrosine-sulfated C5a Receptor N Terminus in Complex with Chemotaxis Inhibitory Protein of Staphylococcus aureus. J.Biol.Chem., 284, 2009
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1BUT
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1PN9
| Crystal structure of an insect delta-class glutathione S-transferase from a DDT-resistant strain of the malaria vector Anopheles gambiae | 分子名称: | Glutathione S-transferase 1-6, S-HEXYLGLUTATHIONE | 著者 | Chen, L, Hall, P.R, Zhou, X.E, Ranson, H, Hemingway, J, Meehan, E.J. | 登録日 | 2003-06-12 | 公開日 | 2003-12-09 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure of an insect delta-class glutathione S-transferase from a DDT-resistant strain of the malaria vector Anopheles gambiae. Acta Crystallogr.,Sect.D, 59, 2003
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1PUL
| Solution structure for the 21KDa caenorhabditis elegans protein CE32E8.3. NORTHEAST STRUCTURAL GENOMICS CONSORTIUM TARGET WR33 | 分子名称: | Hypothetical protein C32E8.3 in chromosome I | 著者 | Tejero, R, Aramini, J.M, Swapna, G.V.T, Monleon, D, Chiang, Y, Macapagal, D, Gunsalus, K.C, Kim, S, Szyperski, T, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2003-06-25 | 公開日 | 2005-06-21 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Backbone 1H, 15N and 13C assignments for the 21 kDa Caenorhabditis elegans homologue of "brain-specific" protein. J.Biomol.Nmr, 28, 2004
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4A1F
| Crystal structure of C-terminal domain of Helicobacter pylori DnaB Helicase | 分子名称: | CITRATE ANION, REPLICATIVE DNA HELICASE | 著者 | Stelter, M, Kapp, U, Timmins, J, Terradot, L. | 登録日 | 2011-09-14 | 公開日 | 2012-03-21 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Architecture of a Dodecameric Bacterial Replicative Helicase. Structure, 20, 2012
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1Q2N
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1PQX
| Solution NMR Structure of Staphylococcus aureus protein SAV1430. Northeast Structural Genomics Consortium Target ZR18. | 分子名称: | conserved hypothetical protein | 著者 | Baran, M.C, Aramini, J.M, Xiao, R, Huang, Y.J, Acton, T.B, Shih, L, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2003-06-19 | 公開日 | 2004-09-07 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution Strucutre of the Hypothetical Staphylococcus Aureus protein SAV1430. Northest Strucutral Genomics Consortium target ZR18 To be Published
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1T3E
| Structural basis of dynamic glycine receptor clustering | 分子名称: | 49-mer fragment of Glycine receptor beta chain, Gephyrin, SULFATE ION | 著者 | Sola, M, Bavro, V.N, Timmins, J, Franz, T, Ricard-Blum, S, Schoehn, G, Ruigrok, R.W.H, Paarmann, I, Saiyed, T, O'Sullivan, G.A. | 登録日 | 2004-04-26 | 公開日 | 2004-07-27 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | 主引用文献 | Structural basis of dynamic glycine receptor clustering by gephyrin Embo J., 23, 2004
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2HJJ
| Solution NMR structure of protein ykfF from Escherichia coli. Northeast Structural Genomics target ER397. | 分子名称: | Hypothetical protein ykfF | 著者 | Swapna, G.V.T, Aramini, J.M, Zhao, L, Cunningham, K, Janjua, H, Ma, L.-C, Xiao, R, Baran, M.C, Acton, T.B, Liu, J, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2006-06-30 | 公開日 | 2006-08-29 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR structure of protein ykfF from Escherichia coli. Northeast Structural Genomics target ER397. To be Published
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2K3A
| NMR solution structure of Staphylococcus saprophyticus CHAP (cysteine, histidine-dependent amidohydrolases/peptidases) domain protein. Northeast Structural Genomics Consortium target SyR11 | 分子名称: | CHAP domain protein | 著者 | Rossi, P, Aramini, J.M, Chen, C.X, Nwosu, C, Cunningham, K.C, Owens, L.A, Xiao, R, Liu, J, Baran, M.C, Swapna, G, Acton, T.B, Rost, B, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2008-04-29 | 公開日 | 2008-05-13 | 最終更新日 | 2024-05-29 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural elucidation of the Cys-His-Glu-Asn proteolytic relay in the secreted CHAP domain enzyme from the human pathogen Staphylococcus saprophyticus. Proteins, 74, 2008
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2HVC
| The Crystal Structure of Ligand-binding Domain (LBD) of human Androgen Receptor in Complex with a selective modulator LGD2226 | 分子名称: | 6-[BIS(2,2,2-TRIFLUOROETHYL)AMINO]-4-(TRIFLUOROMETHYL)QUINOLIN-2(1H)-ONE, Androgen receptor | 著者 | Wang, F, Liu, X.-Q, Li, H, Liang, K.-N, Miner, J.N, Hong, M, Kallel, E.A, van Oeveren, A, Zhi, L, Jiang, T. | 登録日 | 2006-07-28 | 公開日 | 2007-07-31 | 最終更新日 | 2023-10-25 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure of the ligand-binding domain (LBD) of human androgen receptor in complex with a selective modulator LGD2226 ACTA CRYSTALLOGR.,SECT.F, 62, 2006
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2AO6
| Crystal structure of the human androgen receptor ligand binding domain bound with TIF2(iii) 740-753 peptide and R1881 | 分子名称: | (17BETA)-17-HYDROXY-17-METHYLESTRA-4,9,11-TRIEN-3-ONE, 14-mer fragment of Nuclear receptor coactivator 2, androgen receptor | 著者 | He, B, Gampe Jr, R.T, Kole, A.J, Hnat, A.T, Stanley, T.B, An, G, Stewart, E.L, Kalman, R.I, Minges, J.T, Wilson, E.M. | 登録日 | 2005-08-12 | 公開日 | 2005-08-30 | 最終更新日 | 2023-08-23 | 実験手法 | X-RAY DIFFRACTION (1.89 Å) | 主引用文献 | Structural basis for androgen receptor interdomain and coactivator interactions suggests a transition in nuclear receptor activation function dominance Mol.Cell, 16, 2004
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2AZH
| Solution structure of iron-sulfur cluster assembly protein SUFU from Bacillus subtilis, with zinc bound at the active site. Northeast Structural Genomics Consortium target SR17 | 分子名称: | SufU, ZINC ION | 著者 | Kornhaber, G.J, Swapna, G.V.T, Ramelot, T.A, Cort, J.R, Aramini, J.M, Kennedy, M.A, Montelione, G.T, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2005-09-10 | 公開日 | 2005-09-20 | 最終更新日 | 2024-05-22 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution NMR Structure of Zn-Ligated Fe-S Cluster Assembly Scaffold Protein SufU From Bacillus subtilis To be published
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1C2Q
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2BY7
| Is radiation damage dependent on the dose-rate used during macromolecular crystallography data collection | 分子名称: | BENZAMIDINE, CALCIUM ION, CATIONIC TRYPSIN, ... | 著者 | Leiros, H.-K.S, Timmins, J, Ravelli, R.B.G, McSweeney, S.M. | 登録日 | 2005-07-29 | 公開日 | 2006-02-06 | 最終更新日 | 2021-08-04 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Is Radiation Damage Dependent on the Dose-Rate Used During Macromolecular Crystallography Data Collection? Acta Crystallogr.,Sect.D, 62, 2006
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2BYA
| Is radiation damage dependent on the dose-rate used during macromolecular crystallography data collection | 分子名称: | BENZAMIDINE, CALCIUM ION, CATIONIC TRYPSIN, ... | 著者 | Leiros, H.-K.S, Timmins, J, Ravelli, R.B.G, McSweeney, S.M. | 登録日 | 2005-07-29 | 公開日 | 2006-02-06 | 最終更新日 | 2021-08-04 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Is Radiation Damage Dependent on the Dose-Rate Used During Macromolecular Crystallography Data Collection? Acta Crystallogr.,Sect.D, 62, 2006
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2BY6
| Is radiation damage dependent on the dose-rate used during macromolecular crystallography data collection | 分子名称: | BENZAMIDINE, CALCIUM ION, CATIONIC TRYPSIN, ... | 著者 | Leiros, H.-K.S, Timmins, J, Ravelli, R.B.G, McSweeney, S.M. | 登録日 | 2005-07-29 | 公開日 | 2006-02-06 | 最終更新日 | 2021-08-04 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Is Radiation Damage Dependent on the Dose-Rate Used During Macromolecular Crystallography Data Collection? Acta Crystallogr.,Sect.D, 62, 2006
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2BY9
| Is radiation damage dependent on the dose-rate used during macromolecular crystallography data collection | 分子名称: | BENZAMIDINE, CALCIUM ION, CATIONIC TRYPSIN, ... | 著者 | Leiros, H.-K.S, Timmins, J, Ravelli, R.B.G, McSweeney, S.M. | 登録日 | 2005-07-29 | 公開日 | 2006-02-06 | 最終更新日 | 2021-08-04 | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | 主引用文献 | Is Radiation Damage Dependent on the Dose-Rate Used During Macromolecular Crystallography Data Collection? Acta Crystallogr.,Sect.D, 62, 2006
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