3APN
 
 | | Crystal structure of the human wild-type PAD4 protein | | Descriptor: | Protein-arginine deiminase type-4 | | Authors: | Horikoshi, N, Tachiwana, H, Saito, K, Osakabe, A, Sato, M, Yamada, M, Akashi, S, Nishimura, Y, Kagawa, W, Kurumizaka, H. | | Deposit date: | 2010-10-19 | | Release date: | 2011-01-26 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Structural and biochemical analyses of the human PAD4 variant encoded by a functional haplotype gene
Acta Crystallogr.,Sect.D, 67, 2011
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3UXK
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6Z6E
 | | Crystal structure of the HK97 bacteriophage small terminase | | Descriptor: | IODIDE ION, Terminase small subunit | | Authors: | Fung, H.K.H, Chechik, M, Baumann, C.G, Antson, A.A. | | Deposit date: | 2020-05-28 | | Release date: | 2021-06-09 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (1.4 Å) | | Cite: | Structural basis of DNA packaging by a ring-type ATPase from an archetypal viral system.
Nucleic Acids Res., 50, 2022
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3APU
 | | Crystal structure of the A variant of human alpha1-acid glycoprotein | | Descriptor: | Alpha-1-acid glycoprotein 2, TETRAETHYLENE GLYCOL | | Authors: | Nishi, K, Ono, T, Nakamura, T, Fukunaga, N, Izumi, M, Watanabe, H, Suenaga, A, Maruyama, T, Yamagata, Y, Curry, S, Otagiri, M. | | Deposit date: | 2010-10-21 | | Release date: | 2011-02-23 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Structural insights into differences in drug-binding selectivity between two forms of human alpha1-acid glycoprotein genetic variants, the A and F1*S forms.
J. Biol. Chem., 286, 2011
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5HTN
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4NEX
 | | Structure of the N-acetyltransferase domain of X. fastidiosa NAGS/K | | Descriptor: | Acetylglutamate kinase, N-ACETYL-L-GLUTAMATE, SULFATE ION | | Authors: | Zhao, G, Jin, Z, Allewell, N.M, Tuchman, M, Shi, D. | | Deposit date: | 2013-10-30 | | Release date: | 2014-11-12 | | Last modified: | 2023-09-20 | | Method: | X-RAY DIFFRACTION (1.6955 Å) | | Cite: | Structures of the N-acetyltransferase domain of Xylella fastidiosaN-acetyl-L-glutamate synthase/kinase with and without a His tag bound to N-acetyl-L-glutamate.
Acta Crystallogr F Struct Biol Commun, 71, 2015
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6Z6D
 | | Crystal structure of the HK97 bacteriophage large terminase | | Descriptor: | BROMIDE ION, Terminase large subunit | | Authors: | Fung, H.K.H, Chechik, M, Baumann, C.G, Antson, A.A. | | Deposit date: | 2020-05-28 | | Release date: | 2021-06-09 | | Last modified: | 2024-06-19 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural basis of DNA packaging by a ring-type ATPase from an archetypal viral system.
Nucleic Acids Res., 50, 2022
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5HUJ
 | | Crystal Structure of NadE from Streptococcus pyogenes | | Descriptor: | CHLORIDE ION, NH(3)-dependent NAD(+) synthetase | | Authors: | Booth, W.T, Chruszcz, M. | | Deposit date: | 2016-01-27 | | Release date: | 2017-01-25 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.1 Å) | | Cite: | Streptococcus pyogenes quinolinate-salvage pathway-structural and functional studies of quinolinate phosphoribosyl transferase and NH3 -dependent NAD(+) synthetase.
FEBS J., 284, 2017
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5HUH
 | | Crystal Structure of NadE from Streptococcus pyogenes | | Descriptor: | MAGNESIUM ION, NH(3)-dependent NAD(+) synthetase, SULFATE ION | | Authors: | Booth, W.T, Chruszcz, M. | | Deposit date: | 2016-01-27 | | Release date: | 2017-01-25 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.5 Å) | | Cite: | Streptococcus pyogenes quinolinate-salvage pathway-structural and functional studies of quinolinate phosphoribosyl transferase and NH3 -dependent NAD(+) synthetase.
FEBS J., 284, 2017
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3ATR
 | | Geranylgeranyl Reductase (GGR) from Sulfolobus acidocaldarius co-crystallized with its ligand | | Descriptor: | Conserved Archaeal protein, DIHYDROFLAVINE-ADENINE DINUCLEOTIDE, PYROPHOSPHATE, ... | | Authors: | Fujihashi, M, Sasaki, D, Iwata, Y, Yoshimura, T, Hemmi, H, Miki, K. | | Deposit date: | 2011-01-12 | | Release date: | 2011-05-04 | | Last modified: | 2013-12-25 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structure and mutation analysis of archaeal geranylgeranyl reductase
J.Mol.Biol., 409, 2011
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3AUF
 | | Crystal structure of glycinamide ribonucleotide transformylase 1 from Symbiobacterium toebii | | Descriptor: | Glycinamide ribonucleotide transformylase 1 | | Authors: | Kanagawa, M, Baba, S, Nagira, T, Kuramitsu, S, Yokoyama, S, Sampei, G, Kawai, G, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | | Deposit date: | 2011-02-03 | | Release date: | 2012-03-07 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.07 Å) | | Cite: | Structures and reaction mechanisms of the two related enzymes, PurN and PurU.
J.Biochem., 154, 2013
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8OVN
 | | X-ray structure of the SF-iGluSnFR-S72A | | Descriptor: | CITRIC ACID, Putative periplasmic binding transport protein,Green fluorescent protein | | Authors: | Tarnawski, M, Hellweg, L, Bergner, A, Hiblot, J, Leippe, P, Johnsson, K. | | Deposit date: | 2023-04-26 | | Release date: | 2023-05-17 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | X-ray structure of the SF-iGluSnFR-S72A
To Be Published
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8OVO
 | | X-ray structure of the SF-iGluSnFR-S72A in complex with L-aspartate | | Descriptor: | ASPARTIC ACID, Putative periplasmic binding transport protein,Green fluorescent protein | | Authors: | Tarnawski, M, Hellweg, L, Bergner, A, Hiblot, J, Leippe, P, Johnsson, K. | | Deposit date: | 2023-04-26 | | Release date: | 2023-05-17 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | X-ray structure of the SF-iGluSnFR-S72A in complex with L-aspartate
To Be Published
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6Z2S
 | | Crystal structure of adhibin analogue-bound myosin-2 | | Descriptor: | 3,6-dibromo-1-(hydroxymethyl)carbazole, ACETATE ION, ADP METAVANADATE, ... | | Authors: | Ewert, W, Knoelker, H.-J, Tsiavaliaris, G, Preller, M. | | Deposit date: | 2020-05-18 | | Release date: | 2021-06-09 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (3.2 Å) | | Cite: | The synthetic carbazole adhibin acts as selective myosin class-IX inhibitor in lung cancer cells
To Be Published
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8OVP
 | | X-ray structure of the iAspSnFR in complex with L-aspartate | | Descriptor: | ACETATE ION, ASPARTIC ACID, MAGNESIUM ION, ... | | Authors: | Tarnawski, M, Hellweg, L, Bergner, A, Hiblot, J, Leippe, P, Johnsson, K. | | Deposit date: | 2023-04-26 | | Release date: | 2023-05-17 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | X-ray structure of the SF-iAspSnFR in complex with L-aspartate
To Be Published
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5HXW
 | | L-amino acid deaminase from Proteus vulgaris | | Descriptor: | CETYL-TRIMETHYL-AMMONIUM, FLAVIN-ADENINE DINUCLEOTIDE, L-amino acid deaminase | | Authors: | Zhou, H, Ju, Y, Niu, L, Teng, M. | | Deposit date: | 2016-01-31 | | Release date: | 2016-08-03 | | Last modified: | 2023-11-08 | | Method: | X-RAY DIFFRACTION (2.63 Å) | | Cite: | Crystal structure of a membrane-bound l-amino acid deaminase from Proteus vulgaris
J.Struct.Biol., 195, 2016
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8OPQ
 | | Structure of Human Solute Carrier 26 family member A6 (SLC26A6) anion transporter in an inward-facing state | | Descriptor: | CHLORIDE ION, Solute carrier family 26 member 6 | | Authors: | Tippett, D.N, Breen, C, Butler, S.J, Sawicka, M, Dutzler, R. | | Deposit date: | 2023-04-07 | | Release date: | 2023-05-17 | | Last modified: | 2024-07-24 | | Method: | ELECTRON MICROSCOPY (3.28 Å) | | Cite: | Structural and functional properties of the transporter SLC26A6 reveal mechanism of coupled anion exchange.
Elife, 12, 2023
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5HX7
 | | Metal ABC transporter from Listeria monocytogenes | | Descriptor: | Manganese-binding lipoprotein MntA | | Authors: | Osipiuk, J, Zhou, M, Grimshaw, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | | Deposit date: | 2016-01-29 | | Release date: | 2016-02-17 | | Last modified: | 2019-12-11 | | Method: | X-RAY DIFFRACTION (1.75 Å) | | Cite: | Metal ABC transporter from Listeria monocytogenes
to be published
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6ZBR
 | | VEGF-A 13:107 crystallized with 4C bicyclic peptide | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Chains: P, PHOSPHATE ION, ... | | Authors: | Gaucher, J.-F, Broussy, S, Reille-Seroussi, M. | | Deposit date: | 2020-06-09 | | Release date: | 2021-06-23 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Structural and ITC Characterization of Peptide-Protein Binding: Thermodynamic Consequences of Cyclization Constraints, a Case Study on Vascular Endothelial Growth Factor Ligands.
Chemistry, 2022
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7QZX
 | | Human Carbonic Anhydrase II in complex with 4-oxo-N-(4-sulfamoylphenethyl)-1,3,4,6,7,11b-hexahydro-2H-pyrazino[2,1-a]isoquinoline-2-carboxamide | | Descriptor: | 4-oxo-N-(4-sulfamoylphenethyl)-1,3,4,6,7,11b-hexahydro-2H-pyrazino[2,1-a]isoquinoline-2-carboxamide, Carbonic anhydrase 2, GLYCEROL, ... | | Authors: | Angeli, A, Ferraroni, M. | | Deposit date: | 2022-02-01 | | Release date: | 2023-02-15 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.24 Å) | | Cite: | Development of Praziquantel sulphonamide derivatives as antischistosomal drugs.
J Enzyme Inhib Med Chem, 37, 2022
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7R1X
 | | human Carbonic Anhydrase II in complex with 4-oxo-N-(4-sulfamoylphenethyl)-1,3,4,6,7,11b-hexahydro-2H-pyrazino[2,1-a]isoquinoline-2-carbothioamide | | Descriptor: | 4-oxo-N-(4-sulfamoylphenethyl)-1,3,4,6,7,11b-hexahydro-2H-pyrazino[2,1-a]isoquinoline-2-carbothioamide, Carbonic anhydrase 2, GLYCEROL, ... | | Authors: | Angeli, A, Ferraroni, M. | | Deposit date: | 2022-02-03 | | Release date: | 2023-02-15 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.35 Å) | | Cite: | Development of Praziquantel sulphonamide derivatives as antischistosomal drugs.
J Enzyme Inhib Med Chem, 37, 2022
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3AN4
 | | Human PPAR gamma ligand binding domain in complex with a gamma selective agonist MO4R | | Descriptor: | (2R)-2-benzyl-3-(4-propoxy-3-{[({4-[(3S,5S,7S)-tricyclo[3.3.1.1~3,7~]dec-1-yl]phenyl}carbonyl)amino]methyl}phenyl)propanoic acid, Peroxisome proliferator-activated receptor gamma | | Authors: | Oyama, T, Ohashi, M, Waku, T, Miyachi, H, Morikawa, K. | | Deposit date: | 2010-08-30 | | Release date: | 2011-07-27 | | Last modified: | 2023-11-01 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Design, Synthesis, and Structural Analysis of Phenylpropanoic Acid-Type PPAR gamma-Selective Agonists: Discovery of Reversed Stereochemistry-Activity Relationship
J.Med.Chem., 54, 2011
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6ZCD
 | | VEGF-A 13:107 crystallized with 1C bicyclic peptide | | Descriptor: | (4S)-2-METHYL-2,4-PENTANEDIOL, Derived from V114 peptide, PHOSPHATE ION, ... | | Authors: | Gaucher, J.-F, Broussy, S, Reille-Seroussi, M. | | Deposit date: | 2020-06-10 | | Release date: | 2021-06-23 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Structural and ITC Characterization of Peptide-Protein Binding: Thermodynamic Consequences of Cyclization Constraints, a Case Study on Vascular Endothelial Growth Factor Ligands.
Chemistry, 2022
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5HY2
 | | Structure-function analysis of functionally diverse members of the cyclic amide hydrolase family of Toblerone fold enzymes | | Descriptor: | Ring-opening amidohydrolase | | Authors: | Peat, T.S, Balotra, S, Wilding, M, Newman, J, Scott, C. | | Deposit date: | 2016-02-01 | | Release date: | 2017-02-01 | | Last modified: | 2023-09-27 | | Method: | X-RAY DIFFRACTION (2.6 Å) | | Cite: | High-Resolution X-Ray Structures of Two Functionally Distinct Members of the Cyclic Amide Hydrolase Family of Toblerone Fold Enzymes.
Appl. Environ. Microbiol., 83, 2017
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5HYB
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