8HNR
| Molecular structure of Kunitz-type trypsin inhibitor from seeds of Albizia procera | Descriptor: | Kunitz-type trypsin inhibitor | Authors: | Mehmood, S, Thirup, S.S, Saeed, A, Rafiq, M, Khaliq, B, Akrem, A. | Deposit date: | 2022-12-08 | Release date: | 2023-02-01 | Method: | X-RAY DIFFRACTION (1.42 Å) | Cite: | Molecular structure of Kunitz-type trypsin inhibitor from seeds of Albizia procera To Be Published
|
|
6GCC
| Crystal structure of glutathione transferase Xi 3 mutant C56S from Trametes versicolor in complex with dextran-sulfate | Descriptor: | 3,4-di-O-sulfo-alpha-D-glucopyranose-(1-6)-3,4-di-O-sulfo-alpha-D-altropyranose-(1-6)-1,2,3,4-tetra-O-sulfo-alpha-D-allopyranose, Glutathione transferase Xi 3 mutant C56S | Authors: | Schwartz, M, Favier, F, Didierjean, C. | Deposit date: | 2018-04-17 | Release date: | 2018-08-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Trametes versicolor glutathione transferase Xi 3, a dual Cys-GST with catalytic specificities of both Xi and Omega classes. FEBS Lett., 592, 2018
|
|
8H1P
| Cryo-EM structure of the human RAD52 protein | Descriptor: | DNA repair protein RAD52 homolog | Authors: | Kinoshita, C, Takizawa, Y, Saotome, M, Ogino, S, Kurumizaka, H, Kagawa, W. | Deposit date: | 2022-10-03 | Release date: | 2023-02-08 | Last modified: | 2024-07-03 | Method: | ELECTRON MICROSCOPY (3.48 Å) | Cite: | The cryo-EM structure of full-length RAD52 protein contains an undecameric ring. Febs Open Bio, 13, 2023
|
|
6HMZ
| Crystal Structure of a Single-Domain Cyclophilin from Brassica napus Phloem Sap | Descriptor: | Cyclosporin, MAGNESIUM ION, MALONATE ION, ... | Authors: | Falke, S, Hanhart, P, Garbe, M, Thiess, M, Betzel, C, Kehr, J. | Deposit date: | 2018-09-13 | Release date: | 2018-11-21 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.98 Å) | Cite: | Enzyme activity and structural features of three single-domain phloem cyclophilins from Brassica napus. Sci Rep, 9, 2019
|
|
7AH8
| NF-Y bound to suramin inhibitor | Descriptor: | 8,8'-[CARBONYLBIS[IMINO-3,1-PHENYLENECARBONYLIMINO(4-METHYL-3,1-PHENYLENE)CARBONYLIMINO]]BIS-1,3,5-NAPHTHALENETRISULFON IC ACID, CITRATE ANION, GLYCEROL, ... | Authors: | Nardone, V, Chaves-Sanjuan, A, Lapi, M, Nardini, M. | Deposit date: | 2020-09-24 | Release date: | 2021-08-04 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.70001364 Å) | Cite: | Structural Basis of Inhibition of the Pioneer Transcription Factor NF-Y by Suramin. Cells, 9, 2020
|
|
7AT5
| Structure of protein kinase ck2 catalytic subunit (csnk2a1 gene product) in complex with the bivalent inhibitor KN2 | Descriptor: | 1,2-ETHANEDIOL, 2-(3,4-dichlorophenyl)ethanamine, Casein kinase II subunit alpha, ... | Authors: | Lindenblatt, D, Applegate, V, Nickelsen, A, Klussmann, M, Neundorf, I, Goetz, C, Jose, J, Niefind, K. | Deposit date: | 2020-10-29 | Release date: | 2021-08-04 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.77 Å) | Cite: | Molecular Plasticity of Crystalline CK2 alpha ' Leads to KN2, a Bivalent Inhibitor of Protein Kinase CK2 with Extraordinary Selectivity. J.Med.Chem., 65, 2022
|
|
2VCD
| Solution structure of the FKBP-domain of Legionella pneumophila Mip in complex with rapamycin | Descriptor: | Outer membrane protein MIP, RAPAMYCIN IMMUNOSUPPRESSANT DRUG | Authors: | Ceymann, A, Horstmann, M, Ehses, P, Schweimer, K, Paschke, A.-K, Fischer, G, Roesch, P, Faber, C. | Deposit date: | 2007-09-20 | Release date: | 2008-09-02 | Last modified: | 2024-05-15 | Method: | SOLUTION NMR | Cite: | Solution structure of the Legionella pneumophila Mip-rapamycin complex. BMC Struct. Biol., 8, 2008
|
|
1HPC
| REFINED STRUCTURES AT 2 ANGSTROMS AND 2.2 ANGSTROMS OF THE TWO FORMS OF THE H-PROTEIN, A LIPOAMIDE-CONTAINING PROTEIN OF THE GLYCINE DECARBOXYLASE | Descriptor: | 5-[(3S)-1,2-dithiolan-3-yl]pentanoic acid, H PROTEIN OF THE GLYCINE CLEAVAGE SYSTEM, LIPOIC ACID | Authors: | Pares, S, Cohen-Addad, C, Sieker, L, Neuburger, M, Douce, R. | Deposit date: | 1994-02-17 | Release date: | 1995-05-08 | Last modified: | 2024-06-05 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Refined structures at 2 and 2.2 A resolution of two forms of the H-protein, a lipoamide-containing protein of the glycine decarboxylase complex. Acta Crystallogr.,Sect.D, 51, 1995
|
|
6TGW
| |
7AT9
| Structure of protein kinase ck2 catalytic subunit (csnk2a2 gene product) in complex with the ATP-competitive inhibitor MB002 and the alphaD-pocket ligand 3,4-dichlorophenethylamine | Descriptor: | 1,2-ETHANEDIOL, 2-(3,4-dichlorophenyl)ethanamine, 3-(4,5,6,7-tetrabromo-1H-benzotriazol-1-yl)propan-1-ol, ... | Authors: | Lindenblatt, D, Applegate, V, Nickelsen, A, Klussmann, M, Neundorf, I, Goetz, C, Jose, J, Niefind, K. | Deposit date: | 2020-10-29 | Release date: | 2021-08-04 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (1.05 Å) | Cite: | Molecular Plasticity of Crystalline CK2 alpha ' Leads to KN2, a Bivalent Inhibitor of Protein Kinase CK2 with Extraordinary Selectivity. J.Med.Chem., 65, 2022
|
|
3K3G
| Crystal Structure of the Urea Transporter from Desulfovibrio Vulgaris Bound to 1,3-dimethylurea | Descriptor: | 1,3-dimethylurea, GOLD ION, Urea transporter | Authors: | Levin, E.J, Zhou, M, New York Consortium on Membrane Protein Structure (NYCOMPS) | Deposit date: | 2009-10-02 | Release date: | 2009-11-17 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal structure of a bacterial homologue of the kidney urea transporter. Nature, 462, 2009
|
|
6HVG
| |
7ATV
| Structure of protein kinase ck2 catalytic subunit (csnk2a2 gene product) in complex with the bivalent inhibitor KN2 | Descriptor: | 1,2-ETHANEDIOL, CHLORIDE ION, Casein kinase II subunit alpha', ... | Authors: | Lindenblatt, D, Applegate, V, Nickelsen, A, Klussmann, M, Neundorf, I, Goetz, C, Jose, J, Niefind, K. | Deposit date: | 2020-10-31 | Release date: | 2021-08-04 | Last modified: | 2024-06-19 | Method: | X-RAY DIFFRACTION (0.98 Å) | Cite: | Molecular Plasticity of Crystalline CK2 alpha ' Leads to KN2, a Bivalent Inhibitor of Protein Kinase CK2 with Extraordinary Selectivity. J.Med.Chem., 65, 2022
|
|
8H9A
| Crystal structure of chemically modified E. coli ThrS catalytic domain 2 | Descriptor: | N-(2,3-dihydroxybenzoyl)-4-(4-nitrophenyl)-L-threonine, Threonine--tRNA ligase, ZINC ION | Authors: | Qiao, H, Xia, M, Wang, J, Fang, P. | Deposit date: | 2022-10-25 | Release date: | 2023-02-08 | Last modified: | 2023-10-25 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Tyrosine-targeted covalent inhibition of a tRNA synthetase aided by zinc ion. Commun Biol, 6, 2023
|
|
7ATG
| Crystal structure of Z-DNA in complex with putrescinium and potassium cations at ultrahigh-resolution | Descriptor: | 4-azaniumylbutylazanium, DNA (5'-D(*CP*GP*CP*GP*CP*G)-3'), POTASSIUM ION | Authors: | Drozdzal, P, Gilski, M, Jaskolski, M. | Deposit date: | 2020-10-30 | Release date: | 2021-08-11 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (0.6 Å) | Cite: | Crystal structure of Z-DNA in complex with the polyamine putrescine and potassium cations at ultra-high resolution. Acta Crystallogr.,Sect.B, 77, 2021
|
|
6G2R
| Crystal structure of FimH in complex with a tetraflourinated biphenyl alpha D-mannoside | Descriptor: | 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, 4-[3-chloranyl-4-[(2~{R},3~{S},4~{S},5~{S},6~{R})-6-(hydroxymethyl)-3,4,5-tris(oxidanyl)oxan-2-yl]oxy-phenyl]-2,3,5,6-tetrakis(fluoranyl)benzenecarbonitrile, SULFATE ION, ... | Authors: | Jakob, R.P, Schoenemann, W, Cramer, J, Muehlethaler, T, Daetwyler, P, Zihlmann, P, Fiege, B, Sager, C.P, Smiesko, M, Rabbani, S, Eris, D, Schwardt, O, Maier, T, Ernst, B. | Deposit date: | 2018-03-23 | Release date: | 2019-03-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Improvement of Aglycone pi-Stacking Yields Nanomolar to Sub-nanomolar FimH Antagonists. Chemmedchem, 14, 2019
|
|
8GYH
| Crystal structure of Fic25 (apo form) from Streptomyces ficellus | Descriptor: | DegT/DnrJ/EryC1/StrS family aminotransferase, GLYCEROL, IMIDAZOLE | Authors: | Kurosawa, S, Yoshida, A, Tomita, T, Nishiyama, M. | Deposit date: | 2022-09-22 | Release date: | 2023-02-22 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Mechanisms of Sugar Aminotransferase-like Enzymes to Synthesize Stereoisomers of Non-proteinogenic Amino Acids in Natural Product Biosynthesis. Acs Chem.Biol., 18, 2023
|
|
6GEN
| Chromatin remodeller-nucleosome complex at 4.5 A resolution. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-like protein ARP6, BERYLLIUM TRIFLUORIDE ION, ... | Authors: | Willhoft, O, Chua, E.Y.D, Wilkinson, M, Wigley, D.B. | Deposit date: | 2018-04-27 | Release date: | 2018-10-17 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure and dynamics of the yeast SWR1-nucleosome complex. Science, 362, 2018
|
|
8H70
| |
6T5I
| The Transcriptional Regulator PrfA from Listeria Monocytogenes in complex with inhibitor of WNT production (IWP)-2 | Descriptor: | DIMETHYL SULFOXIDE, Listeriolysin positive regulatory factor A, SODIUM ION, ... | Authors: | Oelker, M, Grundstrom, C, Blumenthal, A, Sauer-Eriksson, A.E. | Deposit date: | 2019-10-16 | Release date: | 2021-10-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Inhibition of the master regulator of Listeria monocytogenes virulence enables bacterial clearance from spacious replication vacuoles in infected macrophages. Plos Pathog., 18, 2022
|
|
6TH8
| |
6GEJ
| Chromatin remodeller-nucleosome complex at 3.6 A resolution. | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, Actin-like protein ARP6, BERYLLIUM TRIFLUORIDE ION, ... | Authors: | Willhoft, O, Chua, E.Y.D, Wilkinson, M, Wigley, D.B. | Deposit date: | 2018-04-26 | Release date: | 2018-10-17 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (3.6 Å) | Cite: | Structure and dynamics of the yeast SWR1-nucleosome complex. Science, 362, 2018
|
|
8GYI
| Crystal structure of Fic25 (holo form) from Streptomyces ficellus | Descriptor: | DegT/DnrJ/EryC1/StrS family aminotransferase, GLYCEROL, IMIDAZOLE, ... | Authors: | Kurosawa, S, Yoshida, A, Tomita, T, Nishiyama, M. | Deposit date: | 2022-09-22 | Release date: | 2023-02-22 | Last modified: | 2023-11-29 | Method: | X-RAY DIFFRACTION (1.93 Å) | Cite: | Mechanisms of Sugar Aminotransferase-like Enzymes to Synthesize Stereoisomers of Non-proteinogenic Amino Acids in Natural Product Biosynthesis. Acs Chem.Biol., 18, 2023
|
|
3JZ0
| LinB complexed with clindamycin and AMPCPP | Descriptor: | CLINDAMYCIN, DIPHOSPHOMETHYLPHOSPHONIC ACID ADENOSYL ESTER, Lincosamide nucleotidyltransferase, ... | Authors: | Morar, M, Wright, G.D. | Deposit date: | 2009-09-22 | Release date: | 2009-11-03 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Structure and mechanism of the lincosamide antibiotic adenylyltransferase LinB. Structure, 17, 2009
|
|
6TO6
| Solution structure of the modulator of repression (MOR) of the temperate bacteriophage TP901-1 from Lactococcus lactis | Descriptor: | MOR | Authors: | Rasmussen, K.K, Blackledge, M, Herrmann, T, Lo Leggio, L, Jensen, M.R. | Deposit date: | 2019-12-11 | Release date: | 2020-08-19 | Last modified: | 2024-06-19 | Method: | SOLUTION NMR | Cite: | Revealing the mechanism of repressor inactivation during switching of a temperate bacteriophage. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|