3FGM
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4I9R
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1KSL
| STRUCTURE OF RSUA | Descriptor: | RIBOSOMAL SMALL SUBUNIT PSEUDOURIDINE SYNTHASE A, URACIL | Authors: | Sivaraman, J, Sauve, V, Larocque, R, Stura, E.A, Schrag, J.D, Cygler, M, Matte, A, Montreal-Kingston Bacterial Structural Genomics Initiative (BSGI) | Deposit date: | 2002-01-13 | Release date: | 2002-04-24 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP. Nat.Struct.Biol., 9, 2002
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6G4G
| Full length ectodomain of ectonucleotide phosphodiesterase/pyrophosphatase-3 (NPP3) including the SMB domains but with a partially disordered active site structure | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | Authors: | Dohler, C, Zebisch, M, Strater, N. | Deposit date: | 2018-03-27 | Release date: | 2018-11-07 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | Crystallization of ectonucleotide phosphodiesterase/pyrophosphatase-3 and orientation of the SMB domains in the full-length ectodomain. Acta Crystallogr F Struct Biol Commun, 74, 2018
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1KSV
| STRUCTURE OF RSUA | Descriptor: | RIBOSOMAL SMALL SUBUNIT PSEUDOURIDINE SYNTHASE A, URIDINE-5'-MONOPHOSPHATE | Authors: | Sivaraman, J, Sauve, V, Larocque, R, Stura, E.A, Schrag, J.D, Cygler, M, Matte, A. | Deposit date: | 2002-01-14 | Release date: | 2002-04-24 | Last modified: | 2018-01-31 | Method: | X-RAY DIFFRACTION (2.65 Å) | Cite: | Structure of the 16S rRNA pseudouridine synthase RsuA bound to uracil and UMP. Nat.Struct.Biol., 9, 2002
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6FPX
| Structure of S. pombe Mmi1 in complex with 11-mer RNA | Descriptor: | GLYCEROL, RNA (5'-R(P*UP*UP*UP*AP*AP*AP*CP*CP*UP*A)-3'), YTH domain-containing protein mmi1 | Authors: | Stowell, J.A.W, Hill, C.H, Yu, M, Wagstaff, J.L, McLaughlin, S.H, Freund, S.M.V, Passmore, L.A. | Deposit date: | 2018-02-12 | Release date: | 2018-05-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.97 Å) | Cite: | A low-complexity region in the YTH domain protein Mmi1 enhances RNA binding. J. Biol. Chem., 293, 2018
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1KEW
| The crystal structure of dTDP-D-glucose 4,6-dehydratase (RmlB) from Salmonella enterica serovar Typhimurium with thymidine diphosphate bound | Descriptor: | GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, THYMIDINE-5'-DIPHOSPHATE, ... | Authors: | Allard, S.T.M, Beis, K, Giraud, M.-F, Hegeman, A.D, Gross, J.W, Whitfield, C, Graninger, M, Messner, P, Allen, A.G, Naismith, J.H. | Deposit date: | 2001-11-17 | Release date: | 2002-01-25 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Toward a structural understanding of the dehydratase mechanism. Structure, 10, 2002
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6KEV
| Reduced phosphoribulokinase from Synechococcus elongatus PCC 7942 complexed with adenosine diphosphate and glucose 6-phosphate | Descriptor: | 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 6-O-phosphono-alpha-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, ... | Authors: | Yu, A, Xie, Y, Li, M. | Deposit date: | 2019-07-05 | Release date: | 2020-05-13 | Last modified: | 2020-07-29 | Method: | X-RAY DIFFRACTION (2.506139 Å) | Cite: | Photosynthetic Phosphoribulokinase Structures: Enzymatic Mechanisms and the Redox Regulation of the Calvin-Benson-Bassham Cycle. Plant Cell, 32, 2020
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4GS3
| Dimeric structure of the N-terminal domain of PriB protein from Thermoanaerobacter tencongensis solved ab initio | Descriptor: | Single-stranded DNA-binding protein | Authors: | Liebschner, D, Brzezinski, K, Dauter, M, Dauter, Z, Nowak, M, Kur, J, Olszewski, M. | Deposit date: | 2012-08-27 | Release date: | 2012-09-19 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.09 Å) | Cite: | Dimeric structure of the N-terminal domain of PriB protein from Thermoanaerobacter tengcongensis solved ab initio. Acta Crystallogr.,Sect.D, 68, 2012
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3FJF
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1KFU
| Crystal Structure of Human m-Calpain Form II | Descriptor: | M-CALPAIN LARGE SUBUNIT, M-CALPAIN SMALL SUBUNIT | Authors: | Strobl, S, Fernandez-Catalan, C, Braun, M, Huber, R, Masumoto, H, Nakagawa, K, Irie, A, Sorimachi, H, Bourenkow, G, Bartunik, H, Suzuki, K, Bode, W. | Deposit date: | 2001-11-23 | Release date: | 2001-12-07 | Last modified: | 2024-02-07 | Method: | X-RAY DIFFRACTION (2.5 Å) | Cite: | The crystal structure of calcium-free human m-calpain suggests an electrostatic switch mechanism for activation by calcium. Proc.Natl.Acad.Sci.USA, 97, 2000
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2OVW
| ENDOGLUCANASE I COMPLEXED WITH CELLOBIOSE | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, ENDOGLUCANASE I, beta-D-glucopyranose-(1-4)-beta-D-glucopyranose | Authors: | Sulzenbacher, G, Davies, G.J, Schulein, M. | Deposit date: | 1997-04-04 | Release date: | 1998-04-08 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure of the endoglucanase I from Fusarium oxysporum: native, cellobiose, and 3,4-epoxybutyl beta-D-cellobioside-inhibited forms, at 2.3 A resolution. Biochemistry, 36, 1997
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6TK5
| Femtosecond to millisecond structural changes in a light-driven sodium pump: 800fs+2ps structure of KR2 with extrapolated, light and dark datasets | Descriptor: | EICOSANE, RETINAL, Sodium pumping rhodopsin | Authors: | Skopintsev, P, Ehrenberg, D, Weinert, T, James, D, Kar, R, Johnson, P, Ozerov, D, Furrer, A, Martiel, I, Dworkowski, F, Nass, K, Knopp, G, Cirelli, C, Gashi, D, Mous, S, Wranik, M, Gruhl, T, Kekilli, D, Bruenle, S, Deupi, X, Schertler, G.F.X, Benoit, R, Panneels, V, Nogly, P, Schapiro, I, Milne, C, Heberle, J, Standfuss, J. | Deposit date: | 2019-11-28 | Release date: | 2020-05-27 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.25 Å) | Cite: | Femtosecond-to-millisecond structural changes in a light-driven sodium pump. Nature, 583, 2020
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6FTF
| Regulatory subunit of a cAMP-independent protein kinase A from Trypanosoma cruzi at 1.09 A resolution | Descriptor: | 1,2-ETHANEDIOL, 7-cyano-7-deazainosine, Protein kinase A regulatory subunit, ... | Authors: | Volpato Santos, Y, Lorentzen, E, Basquin, J, Boshart, M. | Deposit date: | 2018-02-21 | Release date: | 2019-04-03 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.09151936 Å) | Cite: | Nucleoside analogue activators of cyclic AMP-independent protein kinase A of Trypanosoma. Nat Commun, 10, 2019
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6KA9
| Crosslinked alpha(Fe-CO)-beta(Ni) human hemoglobin A in the T quaternary structure at 95 K: Dark | Descriptor: | BUT-2-ENEDIAL, CARBON MONOXIDE, Hemoglobin subunit alpha, ... | Authors: | Shibayama, N, Park, S.Y, Ohki, M, Sato-Tomita, A. | Deposit date: | 2019-06-21 | Release date: | 2020-02-19 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Direct observation of ligand migration within human hemoglobin at work. Proc.Natl.Acad.Sci.USA, 117, 2020
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3RLB
| Crystal structure at 2.0 A of the S-component for thiamin from an ECF-type ABC transporter | Descriptor: | 3-(4-AMINO-2-METHYL-PYRIMIDIN-5-YLMETHYL)-5-(2-HYDROXY-ETHYL)-4-METHYL-THIAZOL-3-IUM, ThiT, nonyl beta-D-glucopyranoside | Authors: | Erkens, G.B, Berntsson, R.P.-A, Fulyani, F, Majsnerowska, M, Vujicic-Zagar, A, ter Beek, J, Poolman, B, Slotboom, D.J. | Deposit date: | 2011-04-19 | Release date: | 2011-06-29 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | The structural basis of modularity in ECF-type ABC transporters. Nat.Struct.Mol.Biol., 18, 2011
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1KMZ
| MOLECULAR BASIS OF MITOMYCIN C RESICTANCE IN STREPTOMYCES: CRYSTAL STRUCTURES OF THE MRD PROTEIN WITH AND WITHOUT A DRUG DERIVATIVE | Descriptor: | mitomycin-binding protein | Authors: | Martin, T.W, Dauter, Z, Devedjiev, Y, Sheffield, P, Jelen, F, He, M, Sherman, D, Otlewski, J, Derewenda, Z.S, Derewenda, U. | Deposit date: | 2001-12-17 | Release date: | 2002-07-19 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | Molecular basis of mitomycin C resistance in streptomyces: structure and function of the MRD protein. Structure, 10, 2002
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4NVK
| Predicting protein conformational response in prospective ligand discovery. | Descriptor: | Cytochrome c peroxidase, N~2~,N~2~-diethylquinazoline-2,4-diamine, PHOSPHATE ION, ... | Authors: | Fischer, M, Fraser, J.S. | Deposit date: | 2013-12-05 | Release date: | 2013-12-25 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.56 Å) | Cite: | Incorporation of protein flexibility and conformational energy penalties in docking screens to improve ligand discovery. Nat Chem, 6, 2014
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4L34
| Tankyrase 2 in complex with 4'-tetrazole flavone | Descriptor: | 2-[4-(1H-tetrazol-5-yl)phenyl]-4H-chromen-4-one, GLYCEROL, SULFATE ION, ... | Authors: | Narwal, M, Haikarainen, T, Lehtio, L. | Deposit date: | 2013-06-05 | Release date: | 2013-10-30 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Discovery of tankyrase inhibiting flavones with increased potency and isoenzyme selectivity. J.Med.Chem., 56, 2013
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5RE8
| PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 main protease in complex with Z2737076969 | Descriptor: | 1-(3-fluorophenyl)-N-[(furan-2-yl)methyl]methanamine, 3C-like proteinase, DIMETHYL SULFOXIDE | Authors: | Fearon, D, Owen, C.D, Douangamath, A, Lukacik, P, Powell, A.J, Strain-Damerell, C.M, Resnick, E, Krojer, T, Gehrtz, P, Wild, C, Aimon, A, Brandao-Neto, J, Carbery, A, Dunnett, L, Skyner, R, Snee, M, London, N, Walsh, M.A, von Delft, F. | Deposit date: | 2020-03-15 | Release date: | 2020-03-25 | Last modified: | 2024-03-06 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease. Nat Commun, 11, 2020
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3F7L
| X-ray Crystal Structure of Alvinella pompejana Cu,Zn Superoxide Dismutase | Descriptor: | ACETIC ACID, COPPER (I) ION, COPPER (II) ION, ... | Authors: | Shin, D.S, DiDonato, M, Barondeau, D.P, Getzoff, E.D, Tainer, J.A. | Deposit date: | 2008-11-09 | Release date: | 2009-02-10 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (0.99 Å) | Cite: | Superoxide Dismutase from the Eukaryotic Thermophile Alvinella pompejana: Structures, Stability, Mechanism, and Insights into Amyotrophic Lateral Sclerosis. J.Mol.Biol., 385, 2009
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6FUD
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4L4L
| Structural Analysis of a Phosphoribosylated Inhibitor in Complex with Human Nicotinamide Phosphoribosyltransferase | Descriptor: | 1,2-ETHANEDIOL, 6-({4-[(3,5-difluorophenyl)sulfonyl]benzyl}carbamoyl)-1-(5-O-phosphono-beta-D-ribofuranosyl)imidazo[1,2-a]pyridin-1-ium, Nicotinamide phosphoribosyltransferase, ... | Authors: | Oh, A, Ho, Y, Zak, M, Liu, Y, Yuen, P, Zheng, X, Dragovich, S.P, Wang, W. | Deposit date: | 2013-06-08 | Release date: | 2014-06-11 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.122 Å) | Cite: | Structural and biochemical analyses of the catalysis and potency impact of inhibitor phosphoribosylation by human nicotinamide phosphoribosyltransferase. Chembiochem, 15, 2014
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1KN2
| CATALYTIC ANTIBODY D2.3 COMPLEX | Descriptor: | IG ANTIBODY D2.3 (HEAVY CHAIN), IG ANTIBODY D2.3 (LIGHT CHAIN), PARA-NITROPHENYL PHOSPHONOBUTANOYL L-ALANINE, ... | Authors: | Gigant, B, Knossow, M. | Deposit date: | 2001-12-18 | Release date: | 2002-03-13 | Last modified: | 2024-10-09 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | Remarkable remote chiral recognition in a reaction mediated by a catalytic antibody. J.Am.Chem.Soc., 124, 2002
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5REN
| PanDDA analysis group deposition -- Crystal Structure of SARS-CoV-2 main protease in complex with PCM-0102425 | Descriptor: | 1-[(3R)-3-(1,3-benzothiazol-2-yl)piperidin-1-yl]ethan-1-one, 3C-like proteinase, DIMETHYL SULFOXIDE | Authors: | Fearon, D, Owen, C.D, Douangamath, A, Lukacik, P, Powell, A.J, Strain-Damerell, C.M, Resnick, E, Krojer, T, Gehrtz, P, Wild, C, Aimon, A, Brandao-Neto, J, Carbery, A, Dunnett, L, Skyner, R, Snee, M, London, N, Walsh, M.A, von Delft, F. | Deposit date: | 2020-03-15 | Release date: | 2020-03-25 | Last modified: | 2021-02-24 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Crystallographic and electrophilic fragment screening of the SARS-CoV-2 main protease. Nat Commun, 11, 2020
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