6W82
 
 | | K2P2.1 (TREK-1), 50 mM K+ | | 分子名称: | CADMIUM ION, DECANE, DODECANE, ... | | 著者 | Lolicato, M, Minor, D.L. | | 登録日 | 2020-03-20 | | 公開日 | 2021-01-27 | | 最終更新日 | 2024-11-06 | | 実験手法 | X-RAY DIFFRACTION (3.6 Å) | | 主引用文献 | K 2P channel C-type gating involves asymmetric selectivity filter order-disorder transitions.
Sci Adv, 6, 2020
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6W86
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6XFL
 | | Structural characterization of the type III secretion system pilotin-secretin complex InvH-InvG by NMR spectroscopy | | 分子名称: | Type 3 secretion system pilotin, Type 3 secretion system secretin | | 著者 | Majewski, D.D, Okon, M, Heinkel, F, Robb, C.S, Vuckovic, M, McIntosh, L.P, Strynadka, N.C.J. | | 登録日 | 2020-06-15 | | 公開日 | 2020-09-16 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | Characterization of the Pilotin-Secretin Complex from the Salmonella enterica Type III Secretion System Using Hybrid Structural Methods.
Structure, 29, 2021
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7LGK
 | | Crystal structure of soluble guanylate cyclase activator runcaciguat (BAY 1101042) bound to nostoc H-NOX domain | | 分子名称: | CHLORIDE ION, GLYCEROL, H-NOX domain protein, ... | | 著者 | van den Akker, F, Kumar, V, Schaefer, M. | | 登録日 | 2021-01-20 | | 公開日 | 2021-05-05 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Discovery of the Soluble Guanylate Cyclase Activator Runcaciguat (BAY 1101042).
J.Med.Chem., 64, 2021
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7UT5
 | | Acinetobacter baumannii dihydroorotate dehydrogenase bound with inhibitor DSM186 | | 分子名称: | (4R)-7-methyl-N-[4-(pentafluoro-lambda~6~-sulfanyl)phenyl]imidazo[1,2-a]pyrimidin-5-amine, Dihydroorotate dehydrogenase (quinone), FLAVIN MONONUCLEOTIDE, ... | | 著者 | Deng, X, Phillips, M, Tomchick, D. | | 登録日 | 2022-04-26 | | 公開日 | 2022-12-28 | | 最終更新日 | 2023-10-25 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Repurposed dihydroorotate dehydrogenase inhibitors with efficacy against drug-resistant Acinetobacter baumannii.
Proc.Natl.Acad.Sci.USA, 119, 2022
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6C0F
 | | Yeast nucleolar pre-60S ribosomal subunit (state 2) | | 分子名称: | 5.8S rRNA, 60S ribosomal protein L13-A, 60S ribosomal protein L14-A, ... | | 著者 | Sanghai, Z.A, Miller, L, Barandun, J, Hunziker, M, Chaker-Margot, M, Klinge, S. | | 登録日 | 2017-12-29 | | 公開日 | 2018-03-14 | | 最終更新日 | 2024-10-23 | | 実験手法 | ELECTRON MICROSCOPY (3.7 Å) | | 主引用文献 | Modular assembly of the nucleolar pre-60S ribosomal subunit.
Nature, 556, 2018
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6H2M
 | | Long wavelength Mesh&Collect native SAD phasing on microcrystals | | 分子名称: | CALCIUM ION, Concanavalin-A,Concanavalin-A, MANGANESE (II) ION | | 著者 | Cianci, M, Nanao, M, Schneider, T.R. | | 登録日 | 2018-07-13 | | 公開日 | 2019-03-13 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (1.929 Å) | | 主引用文献 | Long-wavelength Mesh&Collect native SAD phasing from microcrystals.
Acta Crystallogr D Struct Biol, 75, 2019
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5LKD
 | | Crystal structure of the Xi glutathione transferase ECM4 from Saccharomyces cerevisiae in complex with glutathione | | 分子名称: | GLUTATHIONE, Glutathione S-transferase omega-like 2 | | 著者 | Schwartz, M, Didierjean, C, Hecker, A, Girardet, J.M, Morel-Rouhier, M, Gelhaye, E, Favier, F. | | 登録日 | 2016-07-22 | | 公開日 | 2016-10-26 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | | 主引用文献 | Crystal Structure of Saccharomyces cerevisiae ECM4, a Xi-Class Glutathione Transferase that Reacts with Glutathionyl-(hydro)quinones.
Plos One, 11, 2016
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5FMC
 | | Structure of D80A-fructofuranosidase from Xanthophyllomyces dendrorhous complexed with fructose and BIS-TRIS propane buffer | | 分子名称: | 2-[3-(2-HYDROXY-1,1-DIHYDROXYMETHYL-ETHYLAMINO)-PROPYLAMINO]-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | | 著者 | Ramirez-Escudero, M, Sanz-Aparicio, J. | | 登録日 | 2015-11-02 | | 公開日 | 2016-02-10 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.84 Å) | | 主引用文献 | Structural Analysis of Beta-Fructofuranosidase from Xanthophyllomyces Dendrorhous Reveals Unique Features and the Crucial Role of N-Glycosylation in Oligomerization and Activity
J.Biol.Chem., 291, 2016
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4LUG
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6T0Q
 | | Pleurotus Ostreatus Lectin (POL), apo form | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, ... | | 著者 | Destefanis, L, Perduca, M, Bovi, M, Monaco, H.L, Capaldi, S. | | 登録日 | 2019-10-03 | | 公開日 | 2020-02-19 | | 最終更新日 | 2022-12-07 | | 実験手法 | X-RAY DIFFRACTION (2.05 Å) | | 主引用文献 | Structure and properties of the oyster mushroom (Pleurotus ostreatus) lectin.
Glycobiology, 30, 2020
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6T1D
 | | Pleurotus Ostreatus Lectin (POL), compelx with melibiose | | 分子名称: | CALCIUM ION, Lectin, alpha-D-galactopyranose-(1-6)-alpha-D-glucopyranose | | 著者 | Destefanis, L, Perduca, M, Bovi, M, Monaco, H.L, Capaldi, S. | | 登録日 | 2019-10-04 | | 公開日 | 2020-02-19 | | 最終更新日 | 2024-10-23 | | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | | 主引用文献 | Structure and properties of the oyster mushroom (Pleurotus ostreatus) lectin.
Glycobiology, 30, 2020
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5LH3
 | | High dose Thaumatin - 0-40 ms. | | 分子名称: | L(+)-TARTARIC ACID, Thaumatin-1 | | 著者 | Schubert, R, Kapis, S, Heymann, M, Giquel, Y, Bourenkov, G, Schneider, T, Betzel, C, Perbandt, M. | | 登録日 | 2016-07-08 | | 公開日 | 2016-11-09 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | | 主引用文献 | A multicrystal diffraction data-collection approach for studying structural dynamics with millisecond temporal resolution.
IUCrJ, 3, 2016
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6GGJ
 | | Crystal structure of CotB2 in complex with alendronate | | 分子名称: | 4-AMINO-1-HYDROXYBUTANE-1,1-DIYLDIPHOSPHONATE, Cyclooctat-9-en-7-ol synthase, MAGNESIUM ION | | 著者 | Driller, R, Janke, S, Fuchs, M, Warner, E, Mhashal, A.R, Major, D.T, Christmann, M, Brueck, T, Loll, B. | | 登録日 | 2018-05-03 | | 公開日 | 2018-10-10 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Towards a comprehensive understanding of the structural dynamics of a bacterial diterpene synthase during catalysis.
Nat Commun, 9, 2018
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5LI4
 | | bacteriophage phi812K1-420 tail sheath protein after contraction | | 分子名称: | tail sheath protein | | 著者 | Novacek, J, Siborova, M, Benesik, M, Pantucek, R, Doskar, J, Plevka, P. | | 登録日 | 2016-07-14 | | 公開日 | 2017-07-19 | | 最終更新日 | 2024-05-15 | | 実験手法 | ELECTRON MICROSCOPY (4.2 Å) | | 主引用文献 | Structure and genome release of Twort-like Myoviridae phage with a double-layered baseplate.
Proc. Natl. Acad. Sci. U.S.A., 113, 2016
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7S4S
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4JA7
 | | Rat PP5 co-crystallized with P5SA-2 | | 分子名称: | MAGNESIUM ION, Serine/threonine-protein phosphatase 5 | | 著者 | Haslbeck, V, Helmuth, M, Alte, F, Popowicz, G, Schmidt, W, Weiwad, M, Fischer, G, Gemmecker, G, Sattler, M, Striggow, F, Groll, M, Richter, K. | | 登録日 | 2013-02-18 | | 公開日 | 2014-02-19 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Selective activators of protein phosphatase 5 target the auto-inhibitory mechanism.
Biosci.Rep., 35, 2015
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6GVH
 | | Crystal structure of PI3K alpha in complex with 3-(2-Amino-benzooxazol-5-yl)-4-chloro-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin-6-ylamine | | 分子名称: | 5-(6-azanyl-4-chloranyl-1-propan-2-yl-pyrazolo[3,4-d]pyrimidin-3-yl)-1,3-benzoxazol-2-amine, Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit alpha isoform | | 著者 | Ouvry, G, Aurelly, M, Bonnary, L, Borde, E, Bouix-Peter, C, Chantalat, L, Clary, L, Defoin-Platel, C, Deret, S, Forissier, M, Harris, C.S, Isabet, T, Lamy, L, Luzy, A.P, Pascau, J, Soulet, C, Taddei, A, Taquet, N, Tomas, L, Thoreau, E, Varvier, E, Vial, E, Hennequin, L.F. | | 登録日 | 2018-06-21 | | 公開日 | 2019-10-02 | | 最終更新日 | 2024-05-15 | | 実験手法 | X-RAY DIFFRACTION (2.74 Å) | | 主引用文献 | Impact of Minor Structural Modifications on Properties of a Series of mTOR Inhibitors.
Acs Med.Chem.Lett., 10, 2019
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6W75
 | | 1.95 Angstrom Resolution Crystal Structure of NSP10 - NSP16 Complex from SARS-CoV-2 | | 分子名称: | 2'-O-methyltransferase, FORMIC ACID, Non-structural protein 10, ... | | 著者 | Minasov, G, Shuvalova, L, Rosas-Lemus, M, Kiryukhina, O, Wiersum, G, Godzik, A, Jaroszewski, L, Stogios, P.J, Skarina, T, Satchell, K.J.F, Center for Structural Genomics of Infectious Diseases (CSGID) | | 登録日 | 2020-03-18 | | 公開日 | 2020-03-25 | | 最終更新日 | 2023-10-18 | | 実験手法 | X-RAY DIFFRACTION (1.951 Å) | | 主引用文献 | High-resolution structures of the SARS-CoV-2 2'- O -methyltransferase reveal strategies for structure-based inhibitor design.
Sci.Signal., 13, 2020
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6GWS
 | | Crystal structure of human PCNA in complex with three p15 peptides | | 分子名称: | PCNA-associated factor, Proliferating cell nuclear antigen | | 著者 | De March, M, Merino, N, Gonzalez-Magana, A, Romano-Moreno, M, Onesti, S, Blanco, F.J, De Biasio, A. | | 登録日 | 2018-06-25 | | 公開日 | 2018-08-22 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.9 Å) | | 主引用文献 | p15PAF binding to PCNA modulates the DNA sliding surface.
Nucleic Acids Res., 46, 2018
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5WTA
 | | Crystal Structure of Staphylococcus aureus SdrE apo form | | 分子名称: | Serine-aspartate repeat-containing protein E | | 著者 | Wu, M, Zhang, Y, Hang, T, Wang, C, Yang, Y, Zang, J, Zhang, M, Zhang, X. | | 登録日 | 2016-12-10 | | 公開日 | 2017-07-19 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Staphylococcus aureus SdrE captures complement factor H's C-terminus via a novel 'close, dock, lock and latch' mechanism for complement evasion
Biochem. J., 474, 2017
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6W88
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5LN8
 | | Crystal structure of self-complemented MyfA, the major subunit of Myf fimbriae from Yersinia enterocolitica, in complex with galactose | | 分子名称: | Fimbrial protein MyfA,Fimbrial protein MyfA, beta-D-galactopyranose | | 著者 | Pakharukova, N.A, Roy, S, Rahman, M.M, Tuitilla, M, Zavialov, A.V. | | 登録日 | 2016-08-03 | | 公開日 | 2016-08-24 | | 最終更新日 | 2024-01-10 | | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | | 主引用文献 | Structural basis for Myf and Psa fimbriae-mediated tropism of pathogenic strains of Yersinia for host tissues.
Mol.Microbiol., 102, 2016
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5LND
 | | Crystal structure of self-complemented MyfA, the major subunit of Myf fimbriae from Yersinia enterocolitica | | 分子名称: | Fimbrial protein MyfA,Fimbrial protein MyfA,Fimbrial protein MyfA | | 著者 | Pakharukova, N.A, Roy, S, Tuitilla, M, Zavialov, A.V. | | 登録日 | 2016-08-04 | | 公開日 | 2016-08-24 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (1.46 Å) | | 主引用文献 | Structural basis for Myf and Psa fimbriae-mediated tropism of pathogenic strains of Yersinia for host tissues.
Mol.Microbiol., 102, 2016
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6GXO
 | | Cryo-EM structure of a rotated E. coli 70S ribosome in complex with RF3-GDPCP, RF1(GAQ) and P/E-tRNA (State IV) | | 分子名称: | 16S ribosomal RNA, 23S ribosomal RNA, 30S ribosomal protein S10, ... | | 著者 | Graf, M, Huter, P, Maracci, C, Peterek, M, Rodnina, M.V, Wilson, D.N. | | 登録日 | 2018-06-27 | | 公開日 | 2018-08-15 | | 最終更新日 | 2018-10-24 | | 実験手法 | ELECTRON MICROSCOPY (3.9 Å) | | 主引用文献 | Visualization of translation termination intermediates trapped by the Apidaecin 137 peptide during RF3-mediated recycling of RF1.
Nat Commun, 9, 2018
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