8XSX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8xsx by Molmil](/molmil-images/mine/8xsx) | Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA, SERBP1 and eEF2 | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | 著者 | Li, X, Wang, M, Cheng, J. | 登録日 | 2024-01-10 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.4 Å) | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
|
|
8YTE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8yte by Molmil](/molmil-images/mine/8yte) | Crystal Structure of TrkA D5 domain in complex with macrocyclic peptide | 分子名称: | 1,2-ETHANEDIOL, AMINOMETHYLAMIDE, High affinity nerve growth factor receptor, ... | 著者 | Yamada, T, Mihara, K, Ueda, T, Yamauchi, D, Shimizu, M, Ando, A, Mayumi, K, Nakata, Z, Mikamiyama, H. | 登録日 | 2024-03-25 | 公開日 | 2024-07-10 | 最終更新日 | 2024-07-24 | 実験手法 | X-RAY DIFFRACTION (2.26 Å) | 主引用文献 | Discovery and Hit to Lead Optimization of Macrocyclic Peptides as Novel Tropomyosin Receptor Kinase A Antagonists. J.Med.Chem., 67, 2024
|
|
8XT2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8xt2 by Molmil](/molmil-images/mine/8xt2) | Cryo-EM structure of the human 55S mitoribosome with 10uM Tigecycline | 分子名称: | 12s rRNA, 16s rRNA, 39S ribosomal protein L22, ... | 著者 | Li, X, Wang, M, Cheng, J. | 登録日 | 2024-01-10 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
|
|
8YOO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8yoo by Molmil](/molmil-images/mine/8yoo) | Cryo-EM structure of the human 80S ribosome with 100 um Tigecycline | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | 著者 | Li, X, Wang, M, Denk, T, Cheng, J. | 登録日 | 2024-03-13 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2 Å) | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
|
|
8Y46
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8y46 by Molmil](/molmil-images/mine/8y46) | Crystal structure of L-2-keto-3-deoxyfuconate 4-dehydrogenase bound to L-KDF or L-2,4-DKDF | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DI(HYDROXYETHYL)ETHER, L-2,4-diketo-3-deoxyfuconate, ... | 著者 | Akagashi, M, Watanabe, S. | 登録日 | 2024-01-30 | 公開日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.29 Å) | 主引用文献 | Crystal structure of L-2-keto-3-deoxyfuconate 4-dehydrogenase reveals a unique binding mode as a alpha-furanosyl hemiketal of substrates. Sci Rep, 14, 2024
|
|
8XSZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8xsz by Molmil](/molmil-images/mine/8xsz) | Cryo-EM structure of the human 80S ribosome with Tigecycline, E-tRNA and P-tRNA | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | 著者 | Li, X, Wang, M, Cheng, J. | 登録日 | 2024-01-10 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
|
|
8Y4B
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8y4b by Molmil](/molmil-images/mine/8y4b) | |
8XT0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8xt0 by Molmil](/molmil-images/mine/8xt0) | Cryo-EM structure of the human 55S mitoribosome with 5um Tigecycline | 分子名称: | 12s rRNA, 16s rRNA, 39S ribosomal protein L22, ... | 著者 | Li, X, Wang, M, Cheng, J. | 登録日 | 2024-01-10 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
|
|
8YFZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8yfz by Molmil](/molmil-images/mine/8yfz) | CRYSTAL STRUCTURE OF THE EST1 H274E MUTANT AT PH 4.2 | 分子名称: | Carboxylesterase, octyl beta-D-glucopyranoside | 著者 | Unno, H, Oshima, Y, Nishino, T, Nakayama, T, Kusunoki, M. | 登録日 | 2024-02-26 | 公開日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Lowering pH optimum of activity of SshEstI, a slightly alkaliphilic archaeal esterase of the hormone-sensitive lipase family. J.Biosci.Bioeng., 2024
|
|
8Y11
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8y11 by Molmil](/molmil-images/mine/8y11) | |
6ZMK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zmk by Molmil](/molmil-images/mine/6zmk) | Crystal structure of human GFAT-1 L405R | 分子名称: | GLUCOSE-6-PHOSPHATE, GLUTAMIC ACID, Glutamine--fructose-6-phosphate aminotransferase [isomerizing] 1 | 著者 | Ruegenberg, S, Mayr, F, Miethe, S, Atanassov, I, Baumann, U, Denzel, M.S. | 登録日 | 2020-07-02 | 公開日 | 2020-08-05 | 最終更新日 | 2024-01-31 | 実験手法 | X-RAY DIFFRACTION (2.382 Å) | 主引用文献 | Protein kinase A controls the hexosamine pathway by tuning the feedback inhibition of GFAT-1. Nat Commun, 12, 2021
|
|
8YFY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8yfy by Molmil](/molmil-images/mine/8yfy) | CRYSTAL STRUCTURE OF THE EST1 H274D MUTANT AT PH 4.2 | 分子名称: | Carboxylesterase, octyl beta-D-glucopyranoside | 著者 | Unno, H, Oshima, Y, Nishino, T, Nakayama, T, Kusunoki, M. | 登録日 | 2024-02-26 | 公開日 | 2024-07-10 | 最終更新日 | 2024-08-28 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Lowering pH optimum of activity of SshEstI, a slightly alkaliphilic archaeal esterase of the hormone-sensitive lipase family. J.Biosci.Bioeng., 138, 2024
|
|
8XWK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8xwk by Molmil](/molmil-images/mine/8xwk) | |
8YK2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8yk2 by Molmil](/molmil-images/mine/8yk2) | Blood group B alpha-1,3-galactosidase AgaBb from Bifidobacterium bifidum, construct T7-tag_24-700 | 分子名称: | Alpha-galactosidase, GLYCEROL, SODIUM ION, ... | 著者 | Kashima, T, Akama, M, Ashida, H, Fushinobu, S. | 登録日 | 2024-03-04 | 公開日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | 主引用文献 | Crystal Structure of Bifidobacterium bifidum Glycoside Hydrolase Family 110 alpha-Galactosidase Specific for Blood Group B Antigen J.Appl.Glyosci., 2024
|
|
8YOP
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8yop by Molmil](/molmil-images/mine/8yop) | Cryo-EM structure of the human 80S ribosome with 4 um Tigecycline | 分子名称: | 18S rRNA, 28S rRNA, 40S ribosomal protein S10, ... | 著者 | Li, X, Wang, M, Denk, T, Cheng, J. | 登録日 | 2024-03-13 | 公開日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (2.2 Å) | 主引用文献 | Structural basis for differential inhibition of eukaryotic ribosomes by tigecycline. Nat Commun, 15, 2024
|
|
8Y4J
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8y4j by Molmil](/molmil-images/mine/8y4j) | |
8YBK
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ybk by Molmil](/molmil-images/mine/8ybk) | Cryo-EM structure of the human nucleosome containing the H3.1 E97K mutant | 分子名称: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Kimura, T, Hirai, S, Kujirai, T, Ogasawara, M, Takizawa, Y, Kurumizaka, H. | 登録日 | 2024-02-14 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.69 Å) | 主引用文献 | Cryo-EM structure and biochemical analyses of the nucleosome containing the cancer-associated histone H3 mutation E97K. Genes Cells, 2024
|
|
8YBJ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8ybj by Molmil](/molmil-images/mine/8ybj) | Cryo-EM structure of human nucleosome core particle composed of the Widom 601 DNA sequence | 分子名称: | DNA (145-MER), Histone H2A type 1-B/E, Histone H2B type 1-J, ... | 著者 | Kimura, T, Hirai, S, Kujirai, T, Ogasawara, M, Takizawa, Y, Kurumizaka, H. | 登録日 | 2024-02-14 | 公開日 | 2024-07-24 | 実験手法 | ELECTRON MICROSCOPY (2.38 Å) | 主引用文献 | Cryo-EM structure and biochemical analyses of the nucleosome containing the cancer-associated histone H3 mutation E97K. Genes Cells, 2024
|
|
8UK5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8uk5 by Molmil](/molmil-images/mine/8uk5) | Crystal structure of the bromodomain of human ATAD2B in complex with histone H4S1(ph)K5ac | 分子名称: | ATPase family AAA domain-containing protein 2B, Histone H4S1(ph)K5ac | 著者 | Montgomery, C, Phillips, M, Nix, J.C, Glass, K.C. | 登録日 | 2023-10-12 | 公開日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | 主引用文献 | Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains. J.Med.Chem., 67, 2024
|
|
8UHL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8uhl by Molmil](/molmil-images/mine/8uhl) | ATAD2B bromodomain in complex with histone H4 acetylated at lysine 12 | 分子名称: | ATPase family AAA domain-containing protein 2B, Histone H4 | 著者 | Phillips, M, Montgomery, C, Nix, J.C, Glass, K.C. | 登録日 | 2023-10-09 | 公開日 | 2024-06-05 | 実験手法 | X-RAY DIFFRACTION (1.92 Å) | 主引用文献 | Impact of Combinatorial Histone Modifications on Acetyllysine Recognition by the ATAD2 and ATAD2B Bromodomains. J.Med.Chem., 67, 2024
|
|
8UY1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8uy1 by Molmil](/molmil-images/mine/8uy1) | |
8U2Y
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8u2y by Molmil](/molmil-images/mine/8u2y) | Solution structure of the PHD6 finger of MLL4 bound to TET3 | 分子名称: | Histone-lysine N-methyltransferase 2D, Methylcytosine dioxygenase TET3, ZINC ION | 著者 | Mohid, S.A, Zandian, M, Zhang, Y, Kutateladze, T.G. | 登録日 | 2023-09-06 | 公開日 | 2024-06-19 | 実験手法 | SOLUTION NMR | 主引用文献 | MLL4 binds TET3. Structure, 32, 2024
|
|
5ZQH
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5zqh by Molmil](/molmil-images/mine/5zqh) | Crystal structure of Streptococcus transcriptional regulator | 分子名称: | PadR family transcriptional regulator | 著者 | Kim, M, Hong, M. | 登録日 | 2018-04-19 | 公開日 | 2019-05-01 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | 主引用文献 | Structure-based functional analysis of a PadR transcription factor from Streptococcus pneumoniae and characteristic features in the PadR subfamily-2. Biochem.Biophys.Res.Commun., 532, 2020
|
|
6ZYE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6zye by Molmil](/molmil-images/mine/6zye) | YnaI in an open-like conformation | 分子名称: | YnaI,Low conductance mechanosensitive channel YnaI | 著者 | Flegler, V.J, Rasmussen, A, Rao, S, Wu, N, Zenobi, R, Sansom, M.S.P, Hedrich, R, Rasmussen, T, Boettcher, B. | 登録日 | 2020-07-31 | 公開日 | 2020-11-25 | 最終更新日 | 2024-05-01 | 実験手法 | ELECTRON MICROSCOPY (4.1 Å) | 主引用文献 | The MscS-like channel YnaI has a gating mechanism based on flexible pore helices. Proc.Natl.Acad.Sci.USA, 117, 2020
|
|
8UF6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 8uf6 by Molmil](/molmil-images/mine/8uf6) | |