8UY1
Methylenetetrahydrofolate reductase from Chaetomium thermophilum DSM 1495, Active (R) State
Summary for 8UY1
Entry DOI | 10.2210/pdb8uy1/pdb |
Descriptor | Methylenetetrahydrofolate reductase-like protein, FLAVIN-ADENINE DINUCLEOTIDE (3 entities in total) |
Functional Keywords | methylenetetrahydrofolate reductase, nadph activity, oxidoreductase activity, acting on the ch-nh group of donors, nad or nadp as acceptor cobalamin binding, one-carbon metabolism, oxidoreductase |
Biological source | Thermochaetoides thermophila DSM 1495 |
Total number of polymer chains | 4 |
Total formula weight | 284773.17 |
Authors | Yamada, K.,Mendoza, J.,Koutmos, M. (deposition date: 2023-11-12, release date: 2024-06-19, Last modification date: 2024-07-03) |
Primary citation | Yamada, K.,Mendoza, J.,Koutmos, M. Structural basis of S-adenosylmethionine-dependent allosteric transition from active to inactive states in methylenetetrahydrofolate reductase. Nat Commun, 15:5167-5167, 2024 Cited by PubMed: 38886362DOI: 10.1038/s41467-024-49327-5 PDB entries with the same primary citation |
Experimental method | X-RAY DIFFRACTION (3.49 Å) |
Structure validation
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