4PZ1
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![BU of 4pz1 by Molmil](/molmil-images/mine/4pz1) | Crystal structure of a sHIP (UniProt Id: Q99XU0) mutant from Streptococcus pyogenes | 分子名称: | CALCIUM ION, CHLORIDE ION, sHIP | 著者 | Wisniewska, M, Happonen, L, Frick, I.-M, Bjorck, L, Streicher, W, Malmstrom, J, Wikstrom, M. | 登録日 | 2014-03-28 | 公開日 | 2015-03-11 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Functional and structural properties of a novel protein and virulence factor (Protein sHIP) in Streptococcus pyogenes. J.Biol.Chem., 289, 2014
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6YZH
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![BU of 6yzh by Molmil](/molmil-images/mine/6yzh) | Crystal structure of P8C9 bound to CK2alpha | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, Casein kinase II subunit alpha, GLYCEROL, ... | 著者 | Atkinson, E, Iegre, J, Brear, P, Baker, D, Sore, H, Hyvonen, M, Spring, D. | 登録日 | 2020-05-07 | 公開日 | 2021-05-19 | 最終更新日 | 2024-07-10 | 実験手法 | X-RAY DIFFRACTION (1.19 Å) | 主引用文献 | Development of small cyclic peptides targeting the CK2 alpha / beta interface. Chem.Commun.(Camb.), 58, 2022
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188D
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4PL4
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![BU of 4pl4 by Molmil](/molmil-images/mine/4pl4) | Crystal structure of murine IRE1 in complex with OICR464 inhibitor | 分子名称: | 2,5,8,11,14,17,20,23,26,29,32,35,38,41,44,47,50,53,56,59,62,65,68,71,74,77,80-HEPTACOSAOXADOOCTACONTAN-82-OL, 2-methoxy-6-methyl-4-(4-methyl-3,4-dihydro-2H-1,4-benzoxazin-7-yl)phenol, ADENOSINE-5'-DIPHOSPHATE, ... | 著者 | Sanches, M, Duffy, N, Talukdar, M, Thevakumaran, N, Chiovitti, D, Al-awar, R, Patterson, J.B, Sicheri, F. | 登録日 | 2014-05-16 | 公開日 | 2014-09-03 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure and mechanism of action of the hydroxy-aryl-aldehyde class of IRE1 endoribonuclease inhibitors. Nat Commun, 5, 2014
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3CV8
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![BU of 3cv8 by Molmil](/molmil-images/mine/3cv8) | Crystal structure of vitamin D hydroxylase cytochrome P450 105A1 (R84F mutant) | 分子名称: | Cytochrome P450-SU1, PROTOPORPHYRIN IX CONTAINING FE | 著者 | Hayashi, K, Sugimoto, H, Shinkyo, R, Yamada, M, Ikeda, S, Ikushiro, S, Kamakura, M, Shiro, Y, Sakaki, T. | 登録日 | 2008-04-18 | 公開日 | 2008-11-04 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure-based design of a highly active vitamin D hydroxylase from Streptomyces griseolus CYP105A1 Biochemistry, 47, 2008
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6H10
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![BU of 6h10 by Molmil](/molmil-images/mine/6h10) | Crystal Structure of KDM4D with tetrazolylhydrazide ligand NR073 | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, CHLORIDE ION, ... | 著者 | Malecki, P.H, Weiss, M.S, Heinemann, U, Link, A. | 登録日 | 2018-07-10 | 公開日 | 2020-01-29 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.104 Å) | 主引用文献 | Crystal Structure of KDM4D with tetrazolylhydrazide ligand NR073 To be published
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6ZJ3
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![BU of 6zj3 by Molmil](/molmil-images/mine/6zj3) | Cryo-EM structure of the highly atypical cytoplasmic ribosome of Euglena gracilis | 分子名称: | 18S rRNA, 5.8S rRNA, 5S rRNA, ... | 著者 | Matzov, D, Halfon, H, Zimmerman, E, Rozenberg, H, Bashan, A, Gray, M.W, Yonath, A.E, Shalev-Benami, M. | 登録日 | 2020-06-27 | 公開日 | 2020-10-07 | 最終更新日 | 2024-04-24 | 実験手法 | ELECTRON MICROSCOPY (3.15 Å) | 主引用文献 | Cryo-EM structure of the highly atypical cytoplasmic ribosome of Euglena gracilis. Nucleic Acids Res., 48, 2020
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4U43
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![BU of 4u43 by Molmil](/molmil-images/mine/4u43) | MAP4K4 in complex with inhibitor (compound 6) | 分子名称: | Mitogen-activated protein kinase kinase kinase kinase 4, N-(pyridin-3-yl)pyrrolo[2,1-f][1,2,4]triazin-4-amine | 著者 | Harris, S.F, Wu, P, Coons, M. | 登録日 | 2014-07-23 | 公開日 | 2014-09-03 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.18 Å) | 主引用文献 | Fragment-based identification and optimization of a class of potent pyrrolo[2,1-f][1,2,4]triazine MAP4K4 inhibitors. Bioorg.Med.Chem.Lett., 24, 2014
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6Z19
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![BU of 6z19 by Molmil](/molmil-images/mine/6z19) | Crystal structure of P8C9 bound to CK2alpha | 分子名称: | ACETATE ION, ADENOSINE-5'-DIPHOSPHATE, Casein kinase II subunit alpha, ... | 著者 | Atkinson, E, Iegre, J, Brear, P, Baker, D, Sore, H, Hyvonen, M, Spring, D. | 登録日 | 2020-05-13 | 公開日 | 2021-05-26 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (1.47 Å) | 主引用文献 | Development of small cyclic peptides targeting the CK2 alpha / beta interface. Chem.Commun.(Camb.), 58, 2022
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6GKO
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![BU of 6gko by Molmil](/molmil-images/mine/6gko) | Mouse thymidylate synthase cocrystallized with dUMP and soaked in phenolphthalein | 分子名称: | 2'-DEOXYURIDINE 5'-MONOPHOSPHATE, 3,3-bis(4-hydroxyphenyl)-2-benzofuran-1-one, DIMETHYL SULFOXIDE, ... | 著者 | Maj, P, Wilk, P, Jarmula, A, Weiss, M.S, Rode, W. | 登録日 | 2018-05-21 | 公開日 | 2019-06-05 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.839 Å) | 主引用文献 | Thymidylate synthase fragment screening To Be Published
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6GKV
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![BU of 6gkv by Molmil](/molmil-images/mine/6gkv) | Crystal structure of Coclaurine N-Methyltransferase (CNMT) bound to N-methylheliamine and SAH | 分子名称: | 6,7-dimethoxy-2-methyl-1,2,3,4-tetrahydroisoquinolin-2-ium, Coclaurine N-methyltransferase, S-ADENOSYL-L-HOMOCYSTEINE | 著者 | Dunstan, M.S, Levy, C.W. | 登録日 | 2018-05-22 | 公開日 | 2018-06-06 | 最終更新日 | 2024-05-15 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | Structure and Biocatalytic Scope of Coclaurine N-Methyltransferase. Angew. Chem. Int. Ed. Engl., 57, 2018
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3E1Y
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![BU of 3e1y by Molmil](/molmil-images/mine/3e1y) | Crystal structure of human eRF1/eRF3 complex | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, Eukaryotic peptide chain release factor GTP-binding subunit ERF3A, Eukaryotic peptide chain release factor subunit 1 | 著者 | Cheng, Z, Lim, M, Kong, C, Song, H. | 登録日 | 2008-08-05 | 公開日 | 2009-05-19 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (3.8 Å) | 主引用文献 | Structural insights into eRF3 and stop codon recognition by eRF1 Genes Dev., 23, 2009
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4UON
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6Z98
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![BU of 6z98 by Molmil](/molmil-images/mine/6z98) | NMR solution structure of the peach allergen Pru p 1.0101 | 分子名称: | Major allergen Pru p 1 | 著者 | Eidelpes, R, Fuehrer, S, Hofer, F, Kamenik, A.S, Liedl, K.R, Tollinger, M. | 登録日 | 2020-06-03 | 公開日 | 2021-06-30 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structure and Zeatin Binding of the Peach Allergen Pru p 1 . J.Agric.Food Chem., 69, 2021
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1A3Z
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![BU of 1a3z by Molmil](/molmil-images/mine/1a3z) | REDUCED RUSTICYANIN AT 1.9 ANGSTROMS | 分子名称: | COPPER (I) ION, RUSTICYANIN | 著者 | Zhao, D, Shoham, M. | 登録日 | 1998-01-27 | 公開日 | 1998-07-29 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Rusticyanin: Extremes in acid stability and redox potential explained by the crystal structure. Biophys.J., 74, 1998
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6ZBK
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![BU of 6zbk by Molmil](/molmil-images/mine/6zbk) | Crystal structure of the human complex between RPAP3 and TRBP | 分子名称: | RISC-loading complex subunit TARBP2, RNA polymerase II-associated protein 3 | 著者 | Charron, C, Abel, Y, Charpentier, B, Rederstorff, M. | 登録日 | 2020-06-08 | 公開日 | 2021-06-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (1.49 Å) | 主引用文献 | The interaction between RPAP3 and TRBP reveals a possible involvement of the HSP90/R2TP chaperone complex in the regulation of miRNA activity. Nucleic Acids Res., 50, 2022
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6ZE1
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![BU of 6ze1 by Molmil](/molmil-images/mine/6ze1) | human NBD1 of CFTR in complex with nanobody G11a | 分子名称: | 1,2-ETHANEDIOL, ADENOSINE-5'-TRIPHOSPHATE, Cystic fibrosis transmembrane conductance regulator, ... | 著者 | Garcia-Pino, A, Govaerts, C, Scholl, D, Sigoillot, M. | 登録日 | 2020-06-15 | 公開日 | 2021-06-30 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.705 Å) | 主引用文献 | A topological switch in CFTR modulates channel activity and sensitivity to unfolding. Nat.Chem.Biol., 17, 2021
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3AZO
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![BU of 3azo by Molmil](/molmil-images/mine/3azo) | Crystal structure of puromycin hydrolase | 分子名称: | Aminopeptidase, SULFATE ION | 著者 | Matoba, Y, Sugiyama, M. | 登録日 | 2011-05-27 | 公開日 | 2011-07-27 | 最終更新日 | 2011-09-28 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structural evidence that puromycin hydrolase is a new type of aminopeptidase with a prolyl oligopeptidase family fold Proteins, 79, 2011
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6ZHS
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![BU of 6zhs by Molmil](/molmil-images/mine/6zhs) | Uba1 bound to two E2 (Ubc13) molecules | 分子名称: | GLYCEROL, SULFATE ION, Ubiquitin-activating enzyme E1 1, ... | 著者 | Misra, M, Schindelin, H. | 登録日 | 2020-06-23 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.35 Å) | 主引用文献 | ATP induced conformational changes facilitate E1-E2 disulfide bridging in the ubiquitin system. To Be Published
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1A8L
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![BU of 1a8l by Molmil](/molmil-images/mine/1a8l) | PROTEIN DISULFIDE OXIDOREDUCTASE FROM ARCHAEON PYROCOCCUS FURIOSUS | 分子名称: | PROTEIN DISULFIDE OXIDOREDUCTASE, ZINC ION | 著者 | Ren, B, Tibbelin, G, Pascale, D, Rossi, M, Bartolucci, S, Ladenstein, R. | 登録日 | 1998-03-26 | 公開日 | 1999-03-30 | 最終更新日 | 2011-11-16 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | A protein disulfide oxidoreductase from the archaeon Pyrococcus furiosus contains two thioredoxin fold units. Nat.Struct.Biol., 5, 1998
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6ZHT
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6ZHU
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![BU of 6zhu by Molmil](/molmil-images/mine/6zhu) | Yeast Uba1 in complex with Ubc3 and ATP | 分子名称: | ADENOSINE-5'-TRIPHOSPHATE, MAGNESIUM ION, Ubiquitin-activating enzyme E1 1, ... | 著者 | Misra, M, Schindelin, H. | 登録日 | 2020-06-23 | 公開日 | 2022-01-12 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (3.18 Å) | 主引用文献 | ATP induced conformational changes facilitate E1-E2 disulfide bridging in the ubiquitin system To Be Published
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6YWM
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![BU of 6ywm by Molmil](/molmil-images/mine/6ywm) | Crystal structure of SARS-CoV-2 (Covid-19) NSP3 macrodomain in complex with MES | 分子名称: | 1,2-ETHANEDIOL, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, ... | 著者 | Ni, X, Schroeder, M, Olieric, V, Sharpe, E.M, Wojdyla, J.A, Wang, M, Knapp, S, Chaikuad, A, Structural Genomics Consortium (SGC) | 登録日 | 2020-04-29 | 公開日 | 2020-05-06 | 最終更新日 | 2024-01-24 | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | 主引用文献 | Structural Insights into Plasticity and Discovery of Remdesivir Metabolite GS-441524 Binding in SARS-CoV-2 Macrodomain. Acs Med.Chem.Lett., 12, 2021
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3AZP
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6YYL
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![BU of 6yyl by Molmil](/molmil-images/mine/6yyl) | |