9EV5
 
 | | Corynebacterium glutamicum CS176 pyruvate:quinone oxidoreductase (PQO) in complex with FAD and thiamine diphosphate-magnesium ion | | 分子名称: | FLAVIN-ADENINE DINUCLEOTIDE, MAGNESIUM ION, THIAMINE DIPHOSPHATE, ... | | 著者 | Da Silva Lameira, C, Muenssinger, S, Yang, L, Eikmanns, B.J, Bellinzoni, M. | | 登録日 | 2024-03-28 | | 公開日 | 2024-08-07 | | 最終更新日 | 2024-10-30 | | 実験手法 | X-RAY DIFFRACTION (1.863 Å) | | 主引用文献 | Corynebacterium glutamicum pyruvate:quinone oxidoreductase: an enigmatic metabolic enzyme with unusual structural features.
Febs J., 291, 2024
|
|
9EP4
 | | Structure of Integrator subcomplex INTS5/8/15 | | 分子名称: | Integrator complex subunit 15, Integrator complex subunit 5, Integrator complex subunit 8 | | 著者 | Razew, M, Galej, W.P. | | 登録日 | 2024-03-17 | | 公開日 | 2024-06-12 | | 最終更新日 | 2024-07-24 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural basis of the Integrator complex assembly and association with transcription factors.
Mol.Cell, 84, 2024
|
|
9CEZ
 | | Spizellomyces punctatus Fanzor (SpuFz) State 6 | | 分子名称: | DNA (27-MER), DNA (5'-D(P*TP*AP*CP*CP*CP*GP*GP*GP*CP*AP*TP*A)-3'), MAGNESIUM ION, ... | | 著者 | Xu, P, Saito, M, Zhang, F. | | 登録日 | 2024-06-27 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-10-02 | | 実験手法 | ELECTRON MICROSCOPY (3.41 Å) | | 主引用文献 | Structural insights into the diversity and DNA cleavage mechanism of Fanzor.
Cell, 187, 2024
|
|
9ILB
 | | HUMAN INTERLEUKIN-1 BETA | | 分子名称: | PROTEIN (HUMAN INTERLEUKIN-1 BETA) | | 著者 | Yu, B, Blaber, M, Gronenborn, A.M, Clore, G.M, Caspar, D.L.D. | | 登録日 | 1998-10-22 | | 公開日 | 1999-01-06 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.28 Å) | | 主引用文献 | Disordered water within a hydrophobic protein cavity visualized by x-ray crystallography.
Proc.Natl.Acad.Sci.USA, 96, 1999
|
|
8QP0
 | | A hexamer pore in the S-layer of Sulfolobus acidocaldarius formed by SlaA protein | | 分子名称: | S-layer protein A | | 著者 | Gambelli, L, McLaren, M, Isupov, M, Conners, R, Daum, B. | | 登録日 | 2023-09-29 | | 公開日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (11.2 Å) | | 主引用文献 | Structure of the two-component S-layer of the archaeon Sulfolobus acidocaldarius.
Elife, 13, 2024
|
|
9FA4
 | |
9BNR
 | | 4-(2-isothiocyanatoethyl)benzenesulfonamide complexed with Macrophage Migration Inhibitory Factor | | 分子名称: | Macrophage migration inhibitory factor, N-[2-(4-sulfamoylphenyl)ethyl]methanethioamide, SULFATE ION | | 著者 | Fellner, M, Rutledge, M.T, Putha, L, Kok, L.K, Gamble, A.B, Wilbanks, S.M, Vernall, A.J, Tyndall, J.D.A. | | 登録日 | 2024-05-02 | | 公開日 | 2024-07-24 | | 実験手法 | X-RAY DIFFRACTION (1.53 Å) | | 主引用文献 | Covalent isothiocyanate inhibitors of macrophage migration inhibitory factor as potential colorectal cancer treatments.
Chemmedchem, 2024
|
|
6ZTX
 | | Crystal Structure of catalase HPII from Escherichia coli (serendipitously crystallized) | | 分子名称: | 1,2-ETHANEDIOL, CIS-HEME D HYDROXYCHLORIN GAMMA-SPIROLACTONE, Catalase HPII, ... | | 著者 | Grzechowiak, M, Sekula, B, Ruszkowski, M. | | 登録日 | 2020-07-20 | | 公開日 | 2020-10-07 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (1.3 Å) | | 主引用文献 | Serendipitous crystallization of E. coli HPII catalase, a sequel to "the tale usually not told".
Acta Biochim.Pol., 68, 2021
|
|
8ZYO
 | | Cryo-EM Structure of astemizole-bound hERG Channel | | 分子名称: | 1-[(4-fluorophenyl)methyl]-N-{1-[2-(4-methoxyphenyl)ethyl]piperidin-4-yl}-1H-benzimidazol-2-amine, Potassium voltage-gated channel subfamily H member 2 | | 著者 | Miyashita, Y, Moriya, T, Kato, T, Kawasaki, M, Yasuda, Y, Adachi, N, Suzuki, K, Ogasawara, S, Saito, T, Senda, T, Murata, T. | | 登録日 | 2024-06-18 | | 公開日 | 2024-09-18 | | 最終更新日 | 2024-10-09 | | 実験手法 | ELECTRON MICROSCOPY (3.29 Å) | | 主引用文献 | Improved higher resolution cryo-EM structures reveal the binding modes of hERG channel inhibitors.
Structure, 2024
|
|
9CEY
 | | Spizellomyces punctatus Fanzor (SpuFz) State 5 | | 分子名称: | DNA (26-MER), DNA (36-MER), MAGNESIUM ION, ... | | 著者 | Xu, P, Saito, M, Zhang, F. | | 登録日 | 2024-06-27 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-10-02 | | 実験手法 | ELECTRON MICROSCOPY (3.22 Å) | | 主引用文献 | Structural insights into the diversity and DNA cleavage mechanism of Fanzor.
Cell, 187, 2024
|
|
9EVQ
 | |
9CF3
 | | Parasitella parasitica Fanzor (PpFz) State 4 | | 分子名称: | DNA non-target strand, DNA target strand, MAGNESIUM ION, ... | | 著者 | Xu, P, Saito, M, Zhang, F. | | 登録日 | 2024-06-27 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-10-02 | | 実験手法 | ELECTRON MICROSCOPY (3.2 Å) | | 主引用文献 | Structural insights into the diversity and DNA cleavage mechanism of Fanzor.
Cell, 187, 2024
|
|
9J4I
 | | Crystal structure of GH9l Inulin fructotransferases (IFTase) in compex with fruetosyl nystose (GF4) | | 分子名称: | DFA-III-forming inulin fructotransferase, beta-D-fructofuranose-(2-1)-beta-D-fructofuranose-(2-1)-[alpha-D-glucopyranose-(1-2)]beta-D-fructofuranose, beta-D-fructofuranose-(2-1)-beta-D-fructofuranose-(2-1)-beta-D-fructofuranose-(2-1)-[alpha-D-glucopyranose-(1-2)]beta-D-fructofuranose | | 著者 | Chen, G, Wang, Z.X, Yang, Y.Q, Li, Y.G, Zhang, T, Ouyang, S.Y, Zhang, L, Chen, Y, Ruan, X.L, Miao, M. | | 登録日 | 2024-08-09 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-09-18 | | 実験手法 | X-RAY DIFFRACTION (1.96 Å) | | 主引用文献 | Elucidation of the mechanism underlying the sequential catalysis of inulin by fructotransferase.
Int.J.Biol.Macromol., 277, 2024
|
|
9J4J
 | | Crystal structure of GH9l Inulin fructotransferases(IFTase)incomplex with nystose(F3) | | 分子名称: | DFA-III-forming inulin fructotransferase, beta-D-fructofuranose, beta-D-fructofuranose-(1-1)-beta-D-fructofuranose, ... | | 著者 | Chen, G, Wang, Z.X, Yang, Y.Q, Li, Y.G, Zhang, T, Ouyang, S.Y, Zhang, L, Chen, Y, Ruan, X.L, Miao, M. | | 登録日 | 2024-08-09 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-09-18 | | 実験手法 | X-RAY DIFFRACTION (2.803 Å) | | 主引用文献 | Elucidation of the mechanism underlying the sequential catalysis of inulin by fructotransferase.
Int.J.Biol.Macromol., 277, 2024
|
|
9J4K
 | | Crystal structure of GH9l Inulinfructotransferases (IFTase) in complex with GF2 | | 分子名称: | DFA-III-forming inulin fructotransferase, beta-D-fructofuranose-(2-1)-beta-D-fructofuranose-(2-1)-alpha-D-glucopyranose | | 著者 | Chen, G, Wang, Z.X, Yang, Y.Q, Li, Y.G, Zhang, T, Ouyang, S.Y, Zhang, L, Chen, Y, Ruan, X.L, Miao, M. | | 登録日 | 2024-08-09 | | 公開日 | 2024-09-04 | | 最終更新日 | 2024-09-18 | | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | | 主引用文献 | Elucidation of the mechanism underlying the sequential catalysis of inulin by fructotransferase.
Int.J.Biol.Macromol., 277, 2024
|
|
9FJY
 | | Structure of the DNase I- and phalloidin-bound pointed end of F-actin (conformer 2). | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ADENOSINE-5'-DIPHOSPHATE, Actin, ... | | 著者 | Boiero Sanders, M, Oosterheert, W, Hofnagel, O, Bieling, P, Raunser, S. | | 登録日 | 2024-05-31 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-10-02 | | 実験手法 | ELECTRON MICROSCOPY (3.79 Å) | | 主引用文献 | Phalloidin and DNase I-bound F-actin pointed end structures reveal principles of filament stabilization and disassembly.
Nat Commun, 15, 2024
|
|
9C9M
 | | HIV-1 intasome core bound with DTG | | 分子名称: | (4R,12aS)-N-(2,4-difluorobenzyl)-7-hydroxy-4-methyl-6,8-dioxo-3,4,6,8,12,12a-hexahydro-2H-pyrido[1',2':4,5]pyrazino[2,1-b][1,3]oxazine-9-carboxamide, Integrase, MAGNESIUM ION, ... | | 著者 | Li, M, Craigie, R. | | 登録日 | 2024-06-14 | | 公開日 | 2024-07-31 | | 最終更新日 | 2024-08-07 | | 実験手法 | ELECTRON MICROSCOPY (2.01 Å) | | 主引用文献 | HIV-1 Intasomes Assembled with Excess Integrase C-Terminal Domain Protein Facilitate Structural Studies by Cryo-EM and Reveal the Role of the Integrase C-Terminal Tail in HIV-1 Integration.
Viruses, 16, 2024
|
|
9CHW
 | | Crystal structure of human polymerase eta with incoming dAMPnPP nucleotide opposite threofuranosyl thymidine in DNA template | | 分子名称: | 2'-deoxy-5'-O-[(R)-hydroxy{[(R)-hydroxy(phosphonooxy)phosphoryl]amino}phosphoryl]adenosine, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), DNA (5'-D(*CP*AP*TP*(TFT)P*AP*TP*GP*AP*CP*GP*CP*T)-3'), ... | | 著者 | Tomar, R, Stone, M.P, Egli, M. | | 登録日 | 2024-07-02 | | 公開日 | 2024-09-18 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.16 Å) | | 主引用文献 | DNA Replication across alpha-l-(3'-2')-Threofuranosyl Nucleotides Mediated by Human DNA Polymerase eta.
Biochemistry, 63, 2024
|
|
9EQM
 | | Crystal structure of pVHL:EloB:EloC in complex with MP-1-21 | | 分子名称: | (2S,4R)-1-[(2R)-2-[(1-fluoranylcyclopropyl)carbonylamino]-3-methyl-3-[[trans-4-(morpholin-4-ylmethyl)cyclohexyl]methylsulfanyl]butanoyl]-N-[[4-(4-methyl-1,3-thiazol-5-yl)phenyl]methyl]-4-oxidanyl-pyrrolidine-2-carboxamide, Elongin-B, Elongin-C, ... | | 著者 | Kroupova, A, Pierri, M, Liu, X, Ciulli, A. | | 登録日 | 2024-03-21 | | 公開日 | 2024-08-28 | | 実験手法 | X-RAY DIFFRACTION (2.19 Å) | | 主引用文献 | Stereochemical inversion at a 1,4-cyclohexyl PROTAC linker fine-tunes conformation and binding affinity.
Bioorg.Med.Chem.Lett., 110, 2024
|
|
9CIQ
 | | Crystal structure of human polymerase eta with incoming threofuranosyl thymine nucleoside triphosphate opposite template dA | | 分子名称: | CALCIUM ION, DI(HYDROXYETHYL)ETHER, DNA (5'-D(*AP*GP*CP*GP*TP*CP*AP*T)-3'), ... | | 著者 | Patra, A, Tomar, R, Stone, M.P, Egli, M. | | 登録日 | 2024-07-04 | | 公開日 | 2024-09-18 | | 最終更新日 | 2024-10-16 | | 実験手法 | X-RAY DIFFRACTION (2.8 Å) | | 主引用文献 | DNA Replication across alpha-l-(3'-2')-Threofuranosyl Nucleotides Mediated by Human DNA Polymerase eta.
Biochemistry, 63, 2024
|
|
9BZN
 | | High resolution structure of class A Beta-lactamase from Bordetella bronchiseptica RB50 | | 分子名称: | FORMIC ACID, SULFATE ION, class A Beta-lactamase, ... | | 著者 | Maltseva, N, Kim, Y, Endres, M, Joachimiak, A, Center for Structural Biology of Infectious Diseases (CSBID) | | 登録日 | 2024-05-24 | | 公開日 | 2024-06-12 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | High resolution structure of class A Beta-lactamase from Bordetella bronchiseptica RB50
To Be Published
|
|
8QOX
 | | Two-component assembly of SlaA and SlaB S-layer proteins of Sulfolobus acidocaldarius | | 分子名称: | Conserved membrane protein, S-layer protein A | | 著者 | Gambelli, L, McLaren, M, Isupov, M, Conners, R, Daum, B. | | 登録日 | 2023-09-29 | | 公開日 | 2024-02-21 | | 実験手法 | ELECTRON MICROSCOPY (11.2 Å) | | 主引用文献 | Structure of the two-component S-layer of the archaeon Sulfolobus acidocaldarius.
Elife, 13, 2024
|
|
9FCL
 | | CysG(N-16) in complex with SAM from Kitasatospora cystarginea | | 分子名称: | 1,2-ETHANEDIOL, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | | 著者 | Kuttenlochner, W, Beller, P, Kaysser, L, Groll, M. | | 登録日 | 2024-05-15 | | 公開日 | 2024-08-21 | | 最終更新日 | 2024-09-18 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Deciphering the SAM- and metal-dependent mechanism of O-methyltransferases in cystargolide and belactosin biosynthesis: A structure-activity relationship study.
J.Biol.Chem., 300, 2024
|
|
9CEW
 | | Spizellomyces punctatus Fanzor (SpuFz) State 3 | | 分子名称: | DNA (29-MER), DNA (5'-D(P*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*AP*A)-3'), DNA (5'-D(P*CP*GP*GP*TP*AP*CP*CP*CP*GP*GP*GP*CP*AP*TP*A)-3'), ... | | 著者 | Xu, P, Saito, M, Zhang, F. | | 登録日 | 2024-06-27 | | 公開日 | 2024-09-11 | | 最終更新日 | 2024-10-02 | | 実験手法 | ELECTRON MICROSCOPY (2.88 Å) | | 主引用文献 | Structural insights into the diversity and DNA cleavage mechanism of Fanzor.
Cell, 187, 2024
|
|
9EVR
 | |
