1K2P
| Crystal structure of Bruton's tyrosine kinase domain | 分子名称: | Tyrosine-protein kinase BTK | 著者 | Mao, C, Zhou, M, Uckun, F.M. | 登録日 | 2001-09-28 | 公開日 | 2002-06-26 | 最終更新日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Crystal structure of Bruton's tyrosine kinase domain suggests a novel pathway for activation and provides insights into the molecular basis of X-linked agammaglobulinemia. J.Biol.Chem., 276, 2001
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1K33
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6F8N
| Key residues affecting transglycosylation activity in family 18 chitinases - Insights into donor and acceptor subsites | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, CHLORIDE ION, ... | 著者 | Madhuprakash, J, Dalhus, B, Swaroopa Rani, T, Podile, A.R, Eijsink, V.G.H, Sorlie, M. | 登録日 | 2017-12-13 | 公開日 | 2018-07-04 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Key Residues Affecting Transglycosylation Activity in Family 18 Chitinases: Insights into Donor and Acceptor Subsites. Biochemistry, 57, 2018
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5BMM
| Src in complex with DNA-templated macrocyclic inhibitor MC25b | 分子名称: | Proto-oncogene tyrosine-protein kinase Src, macrocyclic inhibitor MC25b | 著者 | Georghiou, G, Guja, K.E, Aleem, S, Kleiner, R.E, Liu, D.R, Miller, W.T, Garcia-Diaz, M, Seeliger, M.A. | 登録日 | 2015-05-22 | 公開日 | 2016-09-21 | 最終更新日 | 2023-11-15 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Structural and Biochemical Basis for Intracellular Kinase Inhibition by Src-specific Peptidic Macrocycles. Cell Chem Biol, 23, 2016
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6J79
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4M65
| In situ thermolysin crystallized on a MiTeGen micromesh with asparagine ligand | 分子名称: | 1,2-ETHANEDIOL, ASPARAGINE, CALCIUM ION, ... | 著者 | Yin, X, Scalia, A, Leroy, L, Cuttitta, C.M, Polizzo, G.M, Ericson, D.L, Roessler, C.G, Campos, O, Agarwal, R, Allaire, M, Orville, A.M, Jackimowicz, R, Ma, M.Y, Sweet, R.M, Soares, A.S. | 登録日 | 2013-08-08 | 公開日 | 2013-10-30 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.6 Å) | 主引用文献 | Hitting the target: fragment screening with acoustic in situ
co-crystallization of proteins plus fragment libraries on
pin-mounted data-collection micromeshes Acta Crystallogr.,Sect.D, D70
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3O3F
| T. maritima RNase H2 D107N in complex with nucleic acid substrate and magnesium ions | 分子名称: | DNA (5'-D(*GP*AP*AP*TP*CP*AP*GP*GP*TP*GP*TP*C)-3'), DNA/RNA (5'-D(*GP*AP*CP*AP*C)-R(P*C)-D(P*TP*GP*AP*TP*TP*C)-3'), MAGNESIUM ION, ... | 著者 | Rychlik, M.P, Chon, H, Cerritelli, S.M, Klimek, P, Crouch, R.J, Nowotny, M. | 登録日 | 2010-07-24 | 公開日 | 2010-12-08 | 最終更新日 | 2024-02-21 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Crystal Structures of RNase H2 in Complex with Nucleic Acid Reveal the Mechanism of RNA-DNA Junction Recognition and Cleavage. Mol.Cell, 40, 2010
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7ZBR
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4M7G
| Streptomyces Erythraeus Trypsin | 分子名称: | Trypsin-like protease | 著者 | Blankenship, E, Vukoti, K, Miyagi, M, Lodowski, D.T. | 登録日 | 2013-08-12 | 公開日 | 2014-03-12 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (0.81 Å) | 主引用文献 | Conformational flexibility in the catalytic triad revealed by the high-resolution crystal structure of Streptomyces erythraeus trypsin in an unliganded state. Acta Crystallogr.,Sect.D, 70, 2014
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6J67
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3O4P
| DFPase at 0.85 Angstrom resolution (H atoms included) | 分子名称: | 1,2-DIMETHOXYETHANE, 1,2-ETHANEDIOL, 1-ETHOXY-2-(2-METHOXYETHOXY)ETHANE, ... | 著者 | Liebschner, D, Elias, M, Koepke, J, Lecomte, C, Guillot, B, Jelsch, C, Chabriere, E. | 登録日 | 2010-07-27 | 公開日 | 2011-08-17 | 最終更新日 | 2024-04-03 | 実験手法 | X-RAY DIFFRACTION (0.85 Å) | 主引用文献 | Hydrogen atoms in protein structures: high-resolution X-ray diffraction structure of the DFPase. BMC Res Notes, 6, 2013
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4M7Z
| Unliganded 1 crystal structure of S25-26 Fab | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, CALCIUM ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Haji-Ghassemi, O, Evans, S.V, Muller-Loennies, S, Saldova, R, Muniyappa, M, Brade, L, Rudd, P.M, Harvey, D.J, Kosma, P, Brade, H. | 登録日 | 2013-08-12 | 公開日 | 2014-04-09 | 最終更新日 | 2020-07-29 | 実験手法 | X-RAY DIFFRACTION (2.75 Å) | 主引用文献 | Groove-type Recognition of Chlamydiaceae-specific Lipopolysaccharide Antigen by a Family of Antibodies Possessing an Unusual Variable Heavy Chain N-Linked Glycan. J.Biol.Chem., 289, 2014
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3NO9
| Crystal Structure of apo fumarate hydratase from Mycobacterium tuberculosis | 分子名称: | Fumarate hydratase class II | 著者 | Li, H, Swanson, S, Yu, M, Hung, L.-W, Sacchettini, J.C, TB Structural Genomics Consortium (TBSGC) | 登録日 | 2010-06-25 | 公開日 | 2010-07-14 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Crystal Structure of apo fumarate hydratase from Mycobacterium tuberculosis To be Published
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2M86
| Solution structure of Hdm2 with engineered cyclotide | 分子名称: | E3 ubiquitin-protein ligase Mdm2, MCo-PMI | 著者 | Majumder, S, Ji, Y, Millard, M, Borra, R, Bi, T, Elnagar, A.Y, Neamati, N, Camarero, J.A. | 登録日 | 2013-05-07 | 公開日 | 2013-07-31 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | In Vivo Activation of the p53 Tumor Suppressor Pathway by an Engineered Cyclotide. J.Am.Chem.Soc., 135, 2013
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3NOV
| Crystal Structure of D17E Isocyanide Hydratase from Pseudomonas fluorescens | 分子名称: | ACETATE ION, ThiJ/PfpI family protein | 著者 | Lakshminarasimhan, M, Madzelan, P, Nan, R, Milkovic, N.M, Wilson, M.A. | 登録日 | 2010-06-25 | 公開日 | 2010-07-07 | 最終更新日 | 2023-09-06 | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | 主引用文献 | Evolution of New Enzymatic Function by Structural Modulation of Cysteine Reactivity in Pseudomonas fluorescens Isocyanide Hydratase. J.Biol.Chem., 285, 2010
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6JAN
| Crystal structure of ABC transporter alpha-glycoside-binding mutant protein R356A in complex with maltose | 分子名称: | 1,2-ETHANEDIOL, ABC transporter, periplasmic substrate-binding protein, ... | 著者 | Kanaujia, S.P, Chandravanshi, M, Gogoi, P. | 登録日 | 2019-01-24 | 公開日 | 2019-10-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.77 Å) | 主引用文献 | Structural and thermodynamic correlation illuminates the selective transport mechanism of disaccharide alpha-glycosides through ABC transporter. Febs J., 287, 2020
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4MAA
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6F10
| GLIC mutant D88N | 分子名称: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | 著者 | Hu, H.D, Delarue, M. | 登録日 | 2017-11-21 | 公開日 | 2018-01-10 | 最終更新日 | 2024-05-08 | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | 主引用文献 | Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel. PLoS Biol., 15, 2017
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4MD1
| Orange species of bacteriorhodopsin from Halobacterium salinarum | 分子名称: | (6E,10E,14E,18E)-2,6,10,15,19,23-hexamethyltetracosa-2,6,10,14,18,22-hexaene, 2,3-DI-PHYTANYL-GLYCEROL, Bacteriorhodopsin, ... | 著者 | Borshchevskiy, V, Erofeev, I, Round, E, Weik, M, Ishchenko, A, Gushchin, I, Mishin, A, Bueldt, G, Gordeliy, V. | 登録日 | 2013-08-22 | 公開日 | 2014-10-08 | 最終更新日 | 2023-09-20 | 実験手法 | X-RAY DIFFRACTION (1.73 Å) | 主引用文献 | Low-dose X-ray radiation induces structural alterations in proteins. Acta Crystallogr.,Sect.D, 70, 2014
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3O6C
| Pyridoxal phosphate biosynthetic protein PdxJ from Campylobacter jejuni | 分子名称: | PHOSPHATE ION, Pyridoxine 5'-phosphate synthase | 著者 | Osipiuk, J, Zhou, M, Kwon, K, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2010-07-28 | 公開日 | 2010-08-11 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (1.87 Å) | 主引用文献 | Pyridoxal phosphate biosynthetic protein PdxJ from Campylobacter jejuni. To be Published
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6J7N
| Crystal structure of toxin TglT (unusual type guanylyltransferase-like toxin, Rv1045) mutant D82A co-expressed with TakA from Mycobacterium tuberculosis | 分子名称: | MAGNESIUM ION, guanylyltransferase-like toxin | 著者 | Yu, X, Gao, X, Zhu, K, Wojdyla, J.A, Wang, M, Cui, S. | 登録日 | 2019-01-18 | 公開日 | 2020-05-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.294 Å) | 主引用文献 | Characterization of a toxin-antitoxin system in Mycobacterium tuberculosis suggests neutralization by phosphorylation as the antitoxicity mechanism. Commun Biol, 3, 2020
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5BSH
| Crystal structure of Medicago truncatula (delta)1-Pyrroline-5-Carboxylate Reductase (MtP5CR) in complex with L-Proline | 分子名称: | PROLINE, Pyrroline-5-carboxylate reductase | 著者 | Ruszkowski, M, Nocek, B, Forlani, G, Dauter, Z. | 登録日 | 2015-06-02 | 公開日 | 2015-11-11 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | The structure of Medicago truncatula delta (1)-pyrroline-5-carboxylate reductase provides new insights into regulation of proline biosynthesis in plants. Front Plant Sci, 6, 2015
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3O6U
| Crystal Structure of CPE2226 protein from Clostridium perfringens. Northeast Structural Genomics Consortium Target CpR195 | 分子名称: | uncharacterized protein CPE2226 | 著者 | Vorobiev, S, Su, M, Seetharaman, J, Patel, P, Xiao, R, Ciccosanti, C, Wang, H, Everett, J.K, Nair, R, Acton, T.B, Rost, B, Montelione, G.T, Hunt, J.F, Tong, L, Northeast Structural Genomics Consortium (NESG) | 登録日 | 2010-07-29 | 公開日 | 2010-08-11 | 最終更新日 | 2017-11-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Crystal Structure of CPE2226 protein from Clostridium perfringens. To be Published
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6J7S
| Crystal structure of toxin TglT (unusual type guanylyltransferase-like toxin, Rv1045) wild type protein from Mycobacterium tuberculosis | 分子名称: | MAGNESIUM ION, guanylyltransferase-like toxin | 著者 | Yu, X, Gao, X, Zhu, K, Wojdyla, J.A, Wang, M, Cui, S. | 登録日 | 2019-01-18 | 公開日 | 2020-05-13 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.102 Å) | 主引用文献 | Characterization of a toxin-antitoxin system in Mycobacterium tuberculosis suggests neutralization by phosphorylation as the antitoxicity mechanism. Commun Biol, 3, 2020
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5BTR
| Crystal structure of SIRT1 in complex with resveratrol and an AMC-containing peptide | 分子名称: | AMC-containing peptide, NAD-dependent protein deacetylase sirtuin-1, RESVERATROL, ... | 著者 | Cao, D, Wang, M, Qiu, X, Liu, D, Jiang, H, Yang, N, Xu, R.M. | 登録日 | 2015-06-03 | 公開日 | 2015-07-08 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural basis for allosteric, substrate-dependent stimulation of SIRT1 activity by resveratrol Genes Dev., 29, 2015
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