4LUN
 
 | | Structure of the N-terminal mIF4G domain from S. cerevisiae Upf2, a protein involved in the degradation of mRNAs containing premature stop codons | | 分子名称: | CHLORIDE ION, Nonsense-mediated mRNA decay protein 2 | | 著者 | Fourati, Z, Roy, B, Millan, C, Courreux, P.D, Kervestin, S, van Tilbeurgh, H, He, F, Uson, I, Jacobson, A, Graille, M. | | 登録日 | 2013-07-25 | | 公開日 | 2014-07-30 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (1.641 Å) | | 主引用文献 | A highly conserved region essential for NMD in the Upf2 N-terminal domain.
J.Mol.Biol., 426, 2014
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5AXS
 | | Crystal structure of CdCat-Fn | | 分子名称: | CADMIUM ION, Ferritin light chain, GLYCEROL, ... | | 著者 | Abe, S, Nakajima, H, Kondo, M, Nakane, T, Nakao, T, Ueno, T, Watanabe, Y. | | 登録日 | 2015-08-01 | | 公開日 | 2015-11-18 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.67 Å) | | 主引用文献 | Construction of an enterobactin analogue with symmetrically arranged monomer subunits of ferritin
Chem.Commun.(Camb.), 51, 2015
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5O5Q
 | | X-ray crystal structure of RapZ from Escherichia coli (P3221 space group) | | 分子名称: | RNase adapter protein RapZ, SULFATE ION | | 著者 | Gonzalez, G.M, Durica-Mitic, S, Hardwick, S.W, Moncrieffe, M, Resch, M, Neumann, P, Ficner, R, Gorke, B, Luisi, B.F. | | 登録日 | 2017-06-02 | | 公開日 | 2017-08-30 | | 最終更新日 | 2017-11-01 | | 実験手法 | X-RAY DIFFRACTION (3.25 Å) | | 主引用文献 | Structural insights into RapZ-mediated regulation of bacterial amino-sugar metabolism.
Nucleic Acids Res., 45, 2017
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6J5A
 | | Cryo-EM structure of the mammalian DP-state ATP synthase FO section | | 分子名称: | ATP synthase membrane subunit 6.8PL, ATP synthase membrane subunit DAPIT, ATP synthase peripheral stalk-membrane subunit b, ... | | 著者 | Gu, J, Zhang, L, Yi, J, Yang, M. | | 登録日 | 2019-01-10 | | 公開日 | 2019-06-26 | | 最終更新日 | 2024-03-27 | | 実験手法 | ELECTRON MICROSCOPY (4.35 Å) | | 主引用文献 | Cryo-EM structure of the mammalian ATP synthase tetramer bound with inhibitory protein IF1.
Science, 364, 2019
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7YXT
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1JE8
 | | Two-Component response regulator NarL/DNA Complex: DNA Bending Found in a High Affinity Site | | 分子名称: | 5'-D(*CP*GP*TP*AP*CP*CP*CP*AP*TP*TP*AP*AP*TP*GP*GP*GP*TP*AP*CP*G)-3', Nitrate/Nitrite Response Regulator Protein NARL, SULFATE ION | | 著者 | Maris, A.E, Sawaya, M.R, Kaczor-Grzeskowiak, M, Jarvis, M.R, Bearson, S.M.D, Kopka, M.L, Schroder, I, Gunsalus, R.P, Dickerson, R.E. | | 登録日 | 2001-06-15 | | 公開日 | 2002-09-27 | | 最終更新日 | 2023-11-15 | | 実験手法 | X-RAY DIFFRACTION (2.12 Å) | | 主引用文献 | Dimerization allows DNA target site recognition by the NarL response regulator.
Nat.Struct.Biol., 9, 2002
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1J9H
 | | Crystal Structure of an RNA Duplex with Uridine Bulges | | 分子名称: | 5'-R(*GP*UP*GP*UP*CP*GP*(CBR)P*AP*C)-3', CALCIUM ION | | 著者 | Xiong, Y, Deng, J, Sudarsanakumar, C, Sundaralingam, M. | | 登録日 | 2001-05-25 | | 公開日 | 2001-10-26 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Crystal structure of an RNA duplex r(gugucgcac)(2) with uridine bulges.
J.Mol.Biol., 313, 2001
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4LRZ
 | | Crystal Structure of the E.coli DhaR(N)-DhaL complex | | 分子名称: | ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, PTS-dependent dihydroxyacetone kinase operon regulatory protein, ... | | 著者 | Shi, R, McDonald, L, Cygler, M, Ekiel, I. | | 登録日 | 2013-07-21 | | 公開日 | 2014-01-29 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2.32 Å) | | 主引用文献 | Coiled-Coil Helix Rotation Selects Repressing or Activating State of Transcriptional Regulator DhaR.
Structure, 22, 2014
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1J9W
 | | Solution Structure of the CAI Michigan 1 Variant | | 分子名称: | 1,2-ETHANEDIOL, CARBONIC ANHYDRASE I, ZINC ION | | 著者 | Briganti, F, Ferraroni, M, Chedwiggen, W.R, Scozzafava, A, Supuran, C.T, Tilli, S. | | 登録日 | 2001-05-29 | | 公開日 | 2001-06-13 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Crystal structure of a zinc-activated variant of human carbonic anhydrase I, CA I Michigan 1: evidence for a second zinc binding site involving arginine coordination.
Biochemistry, 41, 2002
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6J9Q
 | | Crystal structure of Trypanosoma brucei gambiense glycerol kinase complex with AMP-PNP. | | 分子名称: | GLYCEROL, Glycerol kinase, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER | | 著者 | Balogun, E.O, Chishima, T, Ichinose, M, Inaoka, D.K, Kido, Y, Ibrahim, B, de Koning, H, McKerrow, J.H, Watanabe, Y, Nozaki, T, Michels, P.A.M, Harada, S, Kita, K, Shiba, T. | | 登録日 | 2019-01-24 | | 公開日 | 2020-01-29 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | | 主引用文献 | Reaction mechanism of the reverse reaction of African human trypanosomes glycerol kinase.
To Be Published
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7Z0J
 | | human PEX13 SH3 domain in complex with internal FxxxF motif | | 分子名称: | 1,2-ETHANEDIOL, Peroxisomal membrane protein PEX13 | | 著者 | Gaussmann, S, Zak, K, Kreisz, N, Sattler, M. | | 登録日 | 2022-02-23 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Intramolecular autoinhibition of human PEX13 modulates peroxisomal import
Biorxiv, 2022
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6JB0
 | | Crystal structure of ABC transporter alpha-glycoside-binding mutant protein W287A in complex with trehalose | | 分子名称: | 1,2-ETHANEDIOL, 1,3-PROPANDIOL, ABC transporter, ... | | 著者 | Kanaujia, S.P, Chandravanshi, M, Gogoi, P. | | 登録日 | 2019-01-25 | | 公開日 | 2019-10-30 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (1.63 Å) | | 主引用文献 | Structural and thermodynamic correlation illuminates the selective transport mechanism of disaccharide alpha-glycosides through ABC transporter.
Febs J., 287, 2020
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3NOQ
 | | Crystal Structure of C101S Isocyanide Hydratase from Pseudomonas fluorescens | | 分子名称: | 1,2-ETHANEDIOL, 2-[N-CYCLOHEXYLAMINO]ETHANE SULFONIC ACID, ThiJ/PfpI family protein | | 著者 | Lakshminarasimhan, M, Madzelan, P, Nan, R, Milkovic, N.M, Wilson, M.A. | | 登録日 | 2010-06-25 | | 公開日 | 2010-07-07 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (1 Å) | | 主引用文献 | Evolution of New Enzymatic Function by Structural Modulation of Cysteine Reactivity in Pseudomonas fluorescens Isocyanide Hydratase.
J.Biol.Chem., 285, 2010
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7YZH
 | | Schistosoma Mansoni Carbonic Anhydrase in complex with 4-oxo-N-(4-sulfamoylphenethyl)-1,3,4,6,7,11b-hexahydro-2H-pyrazino[2,1-a]isoquinoline-2-carbothioamide | | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 4-oxo-N-(4-sulfamoylphenethyl)-1,3,4,6,7,11b-hexahydro-2H-pyrazino[2,1-a]isoquinoline-2-carbothioamide, Carbonic anhydrase, ... | | 著者 | Angeli, A, Ferraroni, M. | | 登録日 | 2022-02-20 | | 公開日 | 2023-03-01 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.79 Å) | | 主引用文献 | Development of Praziquantel sulphonamide derivatives as antischistosomal drugs.
J Enzyme Inhib Med Chem, 37, 2022
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4LUD
 | | Crystal Structure of HCK in complex with the fluorescent compound SKF86002 | | 分子名称: | 6-(4-fluorophenyl)-5-(pyridin-4-yl)-2,3-dihydroimidazo[2,1-b][1,3]thiazole, CALCIUM ION, CHLORIDE ION, ... | | 著者 | Parker, L.J, Tanaka, A, Handa, N, Honda, K, Tomabechi, Y, Shirouzu, M, Yokoyama, S. | | 登録日 | 2013-07-25 | | 公開日 | 2014-02-12 | | 最終更新日 | 2023-12-06 | | 実験手法 | X-RAY DIFFRACTION (2.85 Å) | | 主引用文献 | Kinase crystal identification and ATP-competitive inhibitor screening using the fluorescent ligand SKF86002.
Acta Crystallogr.,Sect.D, 70, 2014
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6F0M
 | | GLIC mutant E35Q | | 分子名称: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | | 著者 | Hu, H.D, Delarue, M. | | 登録日 | 2017-11-20 | | 公開日 | 2018-01-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.65 Å) | | 主引用文献 | Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
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1JB2
 | | CRYSTAL STRUCTURE OF NTF2 M84E MUTANT | | 分子名称: | NUCLEAR TRANSPORT FACTOR 2 | | 著者 | Chaillan-Huntington, C, Butler, P.J, Huntington, J.A, Akin, D, Feldherr, C, Stewart, M. | | 登録日 | 2001-06-01 | | 公開日 | 2002-03-13 | | 最終更新日 | 2024-05-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | NTF2 monomer-dimer equilibrium.
J.Mol.Biol., 314, 2001
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6ESD
 | | Crystal structure of L-tryptophan oxidase VioA from Chromobacterium violaceum | | 分子名称: | CHLORIDE ION, FLAVIN-ADENINE DINUCLEOTIDE, Flavin-dependent L-tryptophan oxidase VioA | | 著者 | Lai, H.E, Morgan, M, Moore, S, Freemont, P. | | 登録日 | 2017-10-20 | | 公開日 | 2017-12-06 | | 最終更新日 | 2024-01-17 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | A semi-synthetic strategy for derivatization of the violacein natural product scaffold
Biorxiv, 2017
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6F16
 | | GLIC mutant H277Q | | 分子名称: | ACETATE ION, CHLORIDE ION, DIUNDECYL PHOSPHATIDYL CHOLINE, ... | | 著者 | Hu, H.D, Delarue, M. | | 登録日 | 2017-11-21 | | 公開日 | 2018-01-10 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | Full mutational mapping of titratable residues helps to identify proton-sensors involved in the control of channel gating in the Gloeobacter violaceus pentameric ligand-gated ion channel.
PLoS Biol., 15, 2017
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4LXT
 | | Crystal structure WlaRD, a sugar 3N-formyl transferase in the presence of dTdp-Qui3N and 5-N-Formyl-THF | | 分子名称: | 1,2-ETHANEDIOL, 3[N-MORPHOLINO]PROPANE SULFONIC ACID, CHLORIDE ION, ... | | 著者 | Thoden, J.B, Goneau, M.-F, Gilbert, M, Holden, H.M. | | 登録日 | 2013-07-30 | | 公開日 | 2013-08-14 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (1.4 Å) | | 主引用文献 | Structure of a sugar N-formyltransferase from Campylobacter jejuni.
Biochemistry, 52, 2013
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7Z0K
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7Z0I
 | | human PEX13 SH3 domain | | 分子名称: | 1,2-ETHANEDIOL, Peroxisomal membrane protein PEX13, ZINC ION | | 著者 | Gaussmann, S, Zak, K, Sattler, M. | | 登録日 | 2022-02-23 | | 公開日 | 2023-03-08 | | 最終更新日 | 2024-02-07 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Intramolecular autoinhibition of human PEX13 modulates peroxisomal import
Biorxiv, 2022
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1JCC
 | | Crystal Structure of a Novel Alanine-Zipper Trimer at 1.7 A Resolution, V13A,L16A,V20A,L23A,V27A,M30A,V34A mutations | | 分子名称: | MAJOR OUTER MEMBRANE LIPOPROTEIN, ZINC ION | | 著者 | Liu, J, Dai, J, Lu, M. | | 登録日 | 2001-06-08 | | 公開日 | 2003-06-17 | | 最終更新日 | 2023-08-16 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Zinc-Mediated Helix Capping in A Triple-Helical Protein
Biochemistry, 42, 2003
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3NNC
 | | Crystal Structure of CUGBP1 RRM1/2-RNA Complex | | 分子名称: | CUGBP Elav-like family member 1, RNA (5'-R(*UP*GP*UP*GP*UP*GP*UP*UP*GP*UP*GP*UP*G)-3') | | 著者 | Teplova, M, Song, J, Gaw, H, Teplov, A, Patel, D.J. | | 登録日 | 2010-06-23 | | 公開日 | 2010-10-27 | | 最終更新日 | 2023-09-06 | | 実験手法 | X-RAY DIFFRACTION (2.2005 Å) | | 主引用文献 | Structural Insights into RNA Recognition by the Alternate-Splicing Regulator CUG-Binding Protein 1.
Structure, 18, 2010
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6EWX
 | | Structure of Pragmin pseudo-kinase reveals a dimerization mechanism to regulate protein tyrosine phosphorylation and nuclear transcription | | 分子名称: | PEAK1-related kinase-activating pseudokinase 1, SULFATE ION | | 著者 | Gelin, M, Allemand, F, Fournet, A, Labesse, G. | | 登録日 | 2017-11-06 | | 公開日 | 2018-01-31 | | 最終更新日 | 2024-05-08 | | 実験手法 | X-RAY DIFFRACTION (2.771 Å) | | 主引用文献 | Dimerization of the Pragmin Pseudo-Kinase Regulates Protein Tyrosine Phosphorylation.
Structure, 26, 2018
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