5UFK
| Structure of the effector protein SidK (lpg0968) from Legionella pneumophila | 分子名称: | GLYCEROL, effector protein SidK | 著者 | Beyrakhova, K, Xu, C, Boniecki, M.T, Cygler, M. | 登録日 | 2017-01-04 | 公開日 | 2017-05-10 | 最終更新日 | 2020-01-08 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Molecular basis for the binding and modulation of V-ATPase by a bacterial effector protein. PLoS Pathog., 13, 2017
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5TPX
| Bromodomain from Plasmodium Faciparum Gcn5, complexed with compound | 分子名称: | (1S,2S)-N~1~,N~1~-dimethyl-N~2~-(3-methyl[1,2,4]triazolo[3,4-a]phthalazin-6-yl)-1-phenylpropane-1,2-diamine, CHLORIDE ION, Histone acetyltransferase GCN5, ... | 著者 | Lin, Y.H, Hou, C.F.D, MOUSTAKIM, M, DIXON, D.J, Loppnau, P, Tempel, W, Bountra, C, Edwards, A.M, Arrowsmith, C.H, Hui, R, BRENNAN, P.E, Walker, J.R, Structural Genomics Consortium (SGC) | 登録日 | 2016-10-21 | 公開日 | 2017-01-04 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Discovery of a PCAF Bromodomain Chemical Probe. Angew. Chem. Int. Ed. Engl., 56, 2017
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8CN0
| Crystal structure of CREBBP-Y1482N histone acetyltransferase domain in complex with Coenzyme A | 分子名称: | COENZYME A, ZINC ION, histone acetyltransferase | 著者 | Mechaly, A.E, Zhang, W, Haouz, A, Green, M, Rodrigues-Lima, F. | 登録日 | 2023-02-21 | 公開日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.44 Å) | 主引用文献 | Crystal structure of CREBBP-Y1482N histone acetyltransferase domain in complex with Coenzyme A To Be Published
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7LYI
| Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAWJ9-36-3 | 分子名称: | 3C-like proteinase, GLYCEROL, SODIUM ION, ... | 著者 | Sacco, M, Wang, J, Chen, Y. | 登録日 | 2021-03-07 | 公開日 | 2021-03-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Rational Design of Hybrid SARS-CoV-2 Main Protease Inhibitors Guided by the Superimposed Cocrystal Structures with the Peptidomimetic Inhibitors GC-376, Telaprevir, and Boceprevir. Acs Pharmacol Transl Sci, 4, 2021
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5UGV
| DapB from Mycobacterium tuberculosis | 分子名称: | 4-hydroxy-tetrahydrodipicolinate reductase, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, SULFATE ION, ... | 著者 | Pote, S.P, Mank, N, Chruszcz, M. | 登録日 | 2017-01-10 | 公開日 | 2018-01-17 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.25 Å) | 主引用文献 | Comparative structural and mechanistic studies of 4-hydroxy-tetrahydrodipicolinate reductases from Mycobacterium tuberculosis and Vibrio vulnificus. Biochim Biophys Acta Gen Subj, 1865, 2021
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5JCA
| NADP(H) bound NADH-dependent Ferredoxin:NADP Oxidoreductase (NfnI) from Pyrococcus furiosus | 分子名称: | FE2/S2 (INORGANIC) CLUSTER, FLAVIN-ADENINE DINUCLEOTIDE, GLYCEROL, ... | 著者 | Zadvornyy, O.A, Schut, G.J, Nguyen, D.M, Artz, J.H, Tokmina-Lukaszewska, M, Lipscomb, G, Adams, M.W, Peters, J.W. | 登録日 | 2016-04-14 | 公開日 | 2017-04-12 | 最終更新日 | 2024-05-22 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Mechanistic insights into energy conservation by flavin-based electron bifurcation. Nat. Chem. Biol., 13, 2017
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8CNB
| Crystal structure of CREBBP-Y1503C histone acetyltransferase domain in complex with Coenzyme A | 分子名称: | COENZYME A, ZINC ION, histone acetyltransferase | 著者 | Mechaly, A.E, Zhang, W, Haouz, A, Green, M, Rodrigues-Lima, F. | 登録日 | 2023-02-22 | 公開日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (1.986 Å) | 主引用文献 | Crystal structure of CREBBP-Y1503C histone acetyltransferase domain in complex with Coenzyme A To Be Published
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5U87
| NMR structure of the precursor protein PawS1 comprising SFTI-1 and a seed storage albumin | 分子名称: | Preproalbumin PawS1 | 著者 | Franke, B, James, A.M, Mobli, M, Colgrave, M.L, Mylne, J.S, Rosengren, K.J. | 登録日 | 2016-12-14 | 公開日 | 2017-03-01 | 最終更新日 | 2023-06-14 | 実験手法 | SOLUTION NMR | 主引用文献 | NMR structure of the precursor protein PawS1 comprising SFTI-1 and a seed storage albumin to be published
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5JFM
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5U6H
| Solution structure of the zinc fingers 1 and 2 of MBNL1 | 分子名称: | Muscleblind-like protein 1, ZINC ION | 著者 | Phukan, P.D, Park, S, Martinez-Yamout, M.M, Zeeb, M, Dyson, H.J, Wright, P.E. | 登録日 | 2016-12-08 | 公開日 | 2017-08-02 | 最終更新日 | 2024-05-15 | 実験手法 | SOLUTION NMR | 主引用文献 | Structural Basis for Interaction of the Tandem Zinc Finger Domains of Human Muscleblind with Cognate RNA from Human Cardiac Troponin T. Biochemistry, 56, 2017
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8CMQ
| Crystal structure of an 8-repeat consensus TPR superhelix with Tb | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Consensus tetratricopeptide repeat protein, ... | 著者 | Liutkus, M, Rojas, A.L, Cortajarena, A.L. | 登録日 | 2023-02-20 | 公開日 | 2024-03-06 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (1.782 Å) | 主引用文献 | Diverse crystalline protein scaffolds through metal-dependent polymorphism. Protein Sci., 33, 2024
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8CNA
| Crystal structure of CREBBP-R1446C histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA | 分子名称: | ZINC ION, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R,20R)-20-carbamoyl-3-hydroxy-2,2-dimethyl-4,8,14,22-tetraoxo-12-thia-5,9,15,21-tetraazatricos-1-yl dihydrogen diphosphate, histone acetyltransferase | 著者 | Mechaly, A.E, Zhang, W, Haouz, A, Green, M, Rodrigues-Lima, F. | 登録日 | 2023-02-22 | 公開日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.463 Å) | 主引用文献 | Crystal structure of CREBBP-R1446C histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA To Be Published
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8CMZ
| Crystal structure of CREBBP-R1446C histone acetyltransferase domain in complex with Coenzyme A | 分子名称: | COENZYME A, ZINC ION, histone acetyltransferase | 著者 | Mechaly, A.E, Zhang, W, Haouz, A, Green, M, Rodrigues-Lima, F. | 登録日 | 2023-02-21 | 公開日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.252 Å) | 主引用文献 | Crystal structure of CREBBP-R1446C histone acetyltransferase domain in complex with Coenzyme A To Be Published
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2ZX4
| Rhamnose-binding lectin CSL3 | 分子名称: | CSL3, PHOSPHATE ION, alpha-D-galactopyranose-(1-4)-beta-D-galactopyranose, ... | 著者 | Shirai, T, Watababe, Y, Lee, M, Ogawa, T, Muramoto, K. | 登録日 | 2008-12-19 | 公開日 | 2009-06-30 | 最終更新日 | 2023-11-01 | 実験手法 | X-RAY DIFFRACTION (2.7 Å) | 主引用文献 | Structure of rhamnose-binding lectin CSL3: unique pseudo-tetrameric architecture of a pattern recognition protein J.Mol.Biol., 391, 2009
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8CND
| Crystal structure of CREBBP-Y1482N histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA | 分子名称: | ZINC ION, [(2R,3S,4R,5R)-5-(6-amino-9H-purin-9-yl)-4-hydroxy-3-(phosphonooxy)tetrahydrofuran-2-yl]methyl (3R,20R)-20-carbamoyl-3-hydroxy-2,2-dimethyl-4,8,14,22-tetraoxo-12-thia-5,9,15,21-tetraazatricos-1-yl dihydrogen diphosphate, histone acetyltransferase | 著者 | Mechaly, A.E, Zhang, W, Haouz, A, Green, M, Rodrigues-Lima, F. | 登録日 | 2023-02-22 | 公開日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.972 Å) | 主引用文献 | Crystal structure of CREBBP-Y1482N histone acetyltransferase domain in complex with a bisubstrate inhibitor, Lys-CoA To Be Published
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5JCS
| CRYO-EM STRUCTURE OF THE RIX1-REA1 PRE-60S PARTICLE | 分子名称: | 25S ribosomal RNA, 5.8S ribosomal RNA, 5S ribosomal RNA, ... | 著者 | Barrio-Garcia, C, Thoms, M, Flemming, D, Kater, L, Berninghausen, O, Bassler, J, Beckmann, R, Hurt, E. | 登録日 | 2016-04-15 | 公開日 | 2016-11-16 | 最終更新日 | 2024-07-10 | 実験手法 | ELECTRON MICROSCOPY (9.5 Å) | 主引用文献 | Architecture of the Rix1-Rea1 checkpoint machinery during pre-60S-ribosome remodeling Nat.Struct.Mol.Biol., 23, 2016
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1BUZ
| SOLUTION STRUCTURE OF SPOIIAA, A PHOSPHORYLATABLE COMPONENT OF THE SYSTEM THAT REGULATES TRANSCRIPTION FACTOR SIGMA-F OF BACILLUS SUBTILIS NMR, MINIMIZED AVERAGE STRUCTURE | 分子名称: | SPOIIAA | 著者 | Kovacs, H, Comfort, D, Lord, M, Campbell, I.D, Yudkin, M.D. | 登録日 | 1997-09-08 | 公開日 | 1998-07-01 | 最終更新日 | 2024-04-10 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of SpoIIAA, a phosphorylatable component of the system that regulates transcription factor sigmaF of Bacillus subtilis. Proc.Natl.Acad.Sci.USA, 95, 1998
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5F1Q
| Crystal Structure of Periplasmic Dipeptide Transport Protein from Yersinia pestis | 分子名称: | 1,2-ETHANEDIOL, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | 著者 | Kim, Y, Zhou, M, Shatsman, S, Anderson, W.F, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | 登録日 | 2015-11-30 | 公開日 | 2015-12-23 | 最終更新日 | 2019-11-27 | 実験手法 | X-RAY DIFFRACTION (1.956 Å) | 主引用文献 | Crystal Structure of Periplasmic Dipeptide Transport Protein from Yersinia pestis To Be Published
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7ZK1
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6HEE
| Crystal structure of Extracellular Domain 1 (ECD1) of FtsX from S. pneumonie in complex with undecyl-maltoside | 分子名称: | 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, Cell division protein FtsX, SULFATE ION, ... | 著者 | Martinez-Caballero, S, Alcorlo-Pages, M, Hermoso, J.A. | 登録日 | 2018-08-20 | 公開日 | 2019-04-24 | 最終更新日 | 2024-01-17 | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | 主引用文献 | Structure of the Large Extracellular Loop of FtsX and Its Interaction with the Essential Peptidoglycan Hydrolase PcsB in Streptococcus pneumoniae. Mbio, 10, 2019
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8CP8
| Crystal structure of an 8-repeat consensus TPR superhelix with Lead | 分子名称: | (4S)-2-METHYL-2,4-PENTANEDIOL, ACETATE ION, CHLORIDE ION, ... | 著者 | Liutkus, M, Rojas, A.L, Cortajarena, A.L. | 登録日 | 2023-03-02 | 公開日 | 2024-03-13 | 最終更新日 | 2024-04-24 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Diverse crystalline protein scaffolds through metal-dependent polymorphism. Protein Sci., 33, 2024
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7ZKZ
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7LYH
| Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with inhibitor UAWJ9-36-1 | 分子名称: | 3C-like proteinase, GLYCEROL, benzyl (1S,3aR,6aS)-1-({(2S)-1-hydroxy-3-[(3S)-2-oxopyrrolidin-3-yl]propan-2-yl}carbamoyl)hexahydrocyclopenta[c]pyrrole-2(1H)-carboxylate | 著者 | Sacco, M, Wang, J, Chen, Y. | 登録日 | 2021-03-07 | 公開日 | 2021-03-17 | 最終更新日 | 2023-10-18 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Rational Design of Hybrid SARS-CoV-2 Main Protease Inhibitors Guided by the Superimposed Cocrystal Structures with the Peptidomimetic Inhibitors GC-376, Telaprevir, and Boceprevir. Acs Pharmacol Transl Sci, 4, 2021
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7LSS
| Cryo-EM structure of the SARS-CoV-2 spike glycoprotein bound to Fab 2-7 | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Fab 2-7 variable heavy chain, ... | 著者 | Rapp, M, Shapiro, L. | 登録日 | 2021-02-18 | 公開日 | 2021-03-17 | 最終更新日 | 2021-09-29 | 実験手法 | ELECTRON MICROSCOPY (3.72 Å) | 主引用文献 | Structural basis for accommodation of emerging B.1.351 and B.1.1.7 variants by two potent SARS-CoV-2 neutralizing antibodies. Structure, 29, 2021
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7ZKW
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