7ZKZ

Crystal structure of cystinosin from Arabidopsis thaliana bound to two nanobodies

Summary for 7ZKZ

Entry DOI	10.2210/pdb7zkz/pdb
Descriptor	Cystinosin homolog, Llama nanobody, nanobody, ... (4 entities in total)
Functional Keywords	cystinosin; pq-loop protein; proton coupling; cystine transport, membrane protein
Biological source	Arabidopsis thaliana (thale cress) More
Total number of polymer chains	3
Total formula weight	58948.86
Authors	Loebel, M.,Newstead, S. (deposition date: 2022-04-13, release date: 2022-08-31, Last modification date: 2024-01-31)
Primary citation	Lobel, M.,Salphati, S.P.,El Omari, K.,Wagner, A.,Tucker, S.J.,Parker, J.L.,Newstead, S. Structural basis for proton coupled cystine transport by cystinosin. Nat Commun, 13:4845-4845, 2022 Cited by PubMed: 35977944 DOI: 10.1038/s41467-022-32589-2 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.329 Å)

Structure validation