6PGW
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6J28
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![BU of 6j28 by Molmil](/molmil-images/mine/6j28) | Crystal structure of the branched-chain polyamine synthase C9 mutein from Thermus thermophilus (Tth-BpsA C9) in complex with N4-aminopropylspermidine and 5'-methylthioadenosine | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, 5'-DEOXY-5'-METHYLTHIOADENOSINE, FE (III) ION, ... | Authors: | Mizohata, E, Toyoda, M, Fujita, J, Inoue, T. | Deposit date: | 2018-12-31 | Release date: | 2019-06-26 | Last modified: | 2024-03-27 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The C-terminal flexible region of branched-chain polyamine synthase facilitates substrate specificity and catalysis. Febs J., 286, 2019
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7SP0
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![BU of 7sp0 by Molmil](/molmil-images/mine/7sp0) | Crystal structure of human SFPQ L534I mutant in complex with zinc | Descriptor: | Splicing factor, proline- and glutamine-rich, ZINC ION | Authors: | Lee, M. | Deposit date: | 2021-11-01 | Release date: | 2022-10-12 | Last modified: | 2023-10-18 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Familial ALS-associated SFPQ variants promote the formation of SFPQ cytoplasmic aggregates in primary neurons. Open Biology, 12, 2022
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6ESI
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![BU of 6esi by Molmil](/molmil-images/mine/6esi) | Nucleosome breathing : Class 4 | Descriptor: | DNA (133-MER), Histone H2A, Histone H2B 1.1, ... | Authors: | Bilokapic, S, Halic, M. | Deposit date: | 2017-10-20 | Release date: | 2017-12-20 | Last modified: | 2024-05-15 | Method: | ELECTRON MICROSCOPY (6.3 Å) | Cite: | Histone octamer rearranges to adapt to DNA unwrapping. Nat. Struct. Mol. Biol., 25, 2018
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6P3I
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![BU of 6p3i by Molmil](/molmil-images/mine/6p3i) | The structure of condensation and adenylation domains of teixobactin-producing nonribosomal peptide synthetase Txo1 serine module in complex with Mg | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, SULFATE ION, ... | Authors: | Tan, K, Zhou, M, Jedrzejczak, R, Babnigg, G, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-05-23 | Release date: | 2019-06-05 | Last modified: | 2020-03-25 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structures of teixobactin-producing nonribosomal peptide synthetase condensation and adenylation domains. Curr Res Struct Biol, 2, 2020
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6V3C
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7OEY
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![BU of 7oey by Molmil](/molmil-images/mine/7oey) | Neisseria gonnorhoeae variant E93Q at 1.35 angstrom resolution | Descriptor: | GLYCEROL, SODIUM ION, SUCCINIC ACID, ... | Authors: | Rabe von Pappenheim, F, Wensien, M, Tittmann, K. | Deposit date: | 2021-05-04 | Release date: | 2022-02-02 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (1.35 Å) | Cite: | Widespread occurrence of covalent lysine-cysteine redox switches in proteins. Nat.Chem.Biol., 18, 2022
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6PJE
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![BU of 6pje by Molmil](/molmil-images/mine/6pje) | HIV-1 Protease NL4-3 WT in Complex with LR2-43 | Descriptor: | (3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl [(2S,4S,5S)-4-hydroxy-5-({1-[(methoxycarbonyl)amino]cyclopentane-1-carbonyl}amino)-1,6-diphenylhexan-2-yl]carbamate, Protease NL4-3, SULFATE ION | Authors: | Lockbaum, G.J, Rusere, L.N, Henes, M, Kosovrasti, K, Lee, S.K, Spielvogel, E, Nalivaika, E.A, Swanstrom, R, KurtYilmaz, N, Schiffer, C.A, Ali, A. | Deposit date: | 2019-06-28 | Release date: | 2020-07-01 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (1.922 Å) | Cite: | Structural Analysis of Potent Hybrid HIV-1 Protease Inhibitors Containing Bis-tetrahydrofuran in a Pseudosymmetric Dipeptide Isostere. J.Med.Chem., 63, 2020
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1BYP
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![BU of 1byp by Molmil](/molmil-images/mine/1byp) | E43K,D44K DOUBLE MUTANT PLASTOCYANIN FROM SILENE | Descriptor: | COPPER (II) ION, PROTEIN (PLASTOCYANIN) | Authors: | Sugawara, H, Inoue, T, Li, C, Gotowda, M, Hibino, T, Takabe, T, Kai, Y. | Deposit date: | 1998-10-19 | Release date: | 1999-10-19 | Last modified: | 2023-08-09 | Method: | X-RAY DIFFRACTION (1.75 Å) | Cite: | Crystal structures of wild-type and mutant plastocyanins from a higher plant, Silene. J.Biochem.(Tokyo), 125, 1999
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6PJO
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![BU of 6pjo by Molmil](/molmil-images/mine/6pjo) | HIV-1 Protease NL4-3 WT in Complex with LR2-42 | Descriptor: | Protease NL4-3, SULFATE ION, methyl [(1S)-1-cyclopentyl-2-({(2S,4S,5S)-5-[({[(3R,3aS,6aR)-hexahydrofuro[2,3-b]furan-3-yl]oxy}carbonyl)amino]-4-hydroxy-1,6-diphenylhexan-2-yl}amino)-2-oxoethyl]carbamate | Authors: | Lockbaum, G.J, Rusere, L.N, Henes, M, Kosovrasti, K, Lee, S.K, Spielvogel, E, Nalivaika, E.A, Swanstrom, R, KurtYilmaz, N, Schiffer, C.A, Ali, A. | Deposit date: | 2019-06-28 | Release date: | 2020-07-01 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (1.95 Å) | Cite: | Structural Analysis of Potent Hybrid HIV-1 Protease Inhibitors Containing Bis-tetrahydrofuran in a Pseudosymmetric Dipeptide Isostere. J.Med.Chem., 63, 2020
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6MRG
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![BU of 6mrg by Molmil](/molmil-images/mine/6mrg) | FAAH bound to non covalent inhibitor | Descriptor: | (1R)-2-{[6-(2,3-dihydro-1,4-benzodioxin-6-yl)pyrimidin-4-yl]amino}-1-phenylethan-1-ol, Fatty-acid amide hydrolase 1 | Authors: | Saha, A, Shih, A, Mirzadegan, T, Seierstad, M. | Deposit date: | 2018-10-12 | Release date: | 2018-10-31 | Last modified: | 2024-03-13 | Method: | X-RAY DIFFRACTION (2.77 Å) | Cite: | Predicting the Binding of Fatty Acid Amide Hydrolase Inhibitors by Free Energy Perturbation. J Chem Theory Comput, 14, 2018
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6V4W
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![BU of 6v4w by Molmil](/molmil-images/mine/6v4w) | The crystal structure of a beta-lactamase from Chitinophaga pinensis DSM 2588 | Descriptor: | 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, ACETATE ION, Beta-lactamase, ... | Authors: | Tan, K, Welk, L, Endres, M, Joachimiak, A, Center for Structural Genomics of Infectious Diseases (CSGID) | Deposit date: | 2019-12-02 | Release date: | 2019-12-18 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.29 Å) | Cite: | The crystal structure of a beta-lactamase from Chitinophaga pinensis DSM 2588 To Be Published
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6PKV
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![BU of 6pkv by Molmil](/molmil-images/mine/6pkv) | Cryo-EM structure of the zebrafish TRPM2 channel in the apo conformation, processed with C4 symmetry | Descriptor: | Transient receptor potential cation channel subfamily M member 2 | Authors: | Yin, Y, Wu, M, Hsu, A.L, Borschel, W.F, Borgnia, M.J, Lander, G.C, Lee, S.-Y. | Deposit date: | 2019-06-30 | Release date: | 2019-08-28 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (4.3 Å) | Cite: | Visualizing structural transitions of ligand-dependent gating of the TRPM2 channel. Nat Commun, 10, 2019
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6V5V
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![BU of 6v5v by Molmil](/molmil-images/mine/6v5v) | Structure of gamma-tubulin in the native human gamma-tubulin ring complex | Descriptor: | GUANOSINE-5'-DIPHOSPHATE, Tubulin gamma-1 chain | Authors: | Wieczorek, M, Urnavicius, L, Ti, S, Molloy, K.R, Chait, B.T, Kapoor, T.M. | Deposit date: | 2019-12-04 | Release date: | 2020-01-01 | Last modified: | 2024-03-06 | Method: | ELECTRON MICROSCOPY (3.8 Å) | Cite: | Asymmetric Molecular Architecture of the Human gamma-Tubulin Ring Complex. Cell, 180, 2020
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1XHN
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7OCI
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![BU of 7oci by Molmil](/molmil-images/mine/7oci) | Cryo-EM structure of yeast Ost6p containing oligosaccharyltransferase complex | Descriptor: | 1,2-dioleoyl-sn-glycero-3-phosphoethanolamine, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, ... | Authors: | Wild, R, Neuhaus, J.D, Eyring, J, Irobalieva, R.N, Kowal, J, Lin, C.W, Locher, K.P, Aebi, M. | Deposit date: | 2021-04-27 | Release date: | 2022-02-16 | Method: | ELECTRON MICROSCOPY (3.46 Å) | Cite: | Functional analysis of Ost3p and Ost6p containing yeast oligosaccharyltransferases. Glycobiology, 31, 2021
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6V75
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![BU of 6v75 by Molmil](/molmil-images/mine/6v75) | Crystal Structure of Human PKM2 in Complex with L-aspartate | Descriptor: | 1,6-di-O-phosphono-beta-D-fructofuranose, ASPARTIC ACID, CHLORIDE ION, ... | Authors: | Nandi, S, Dey, M. | Deposit date: | 2019-12-07 | Release date: | 2020-03-18 | Last modified: | 2023-10-11 | Method: | X-RAY DIFFRACTION (2.85 Å) | Cite: | Biochemical and structural insights into how amino acids regulate pyruvate kinase muscle isoform 2. J.Biol.Chem., 295, 2020
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1X6C
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![BU of 1x6c by Molmil](/molmil-images/mine/1x6c) | Solution structures of the SH2 domain of human protein-tyrosine phosphatase SHP-1 | Descriptor: | Tyrosine-protein phosphatase, non-receptor type 6 | Authors: | Sato, M, Koshiba, S, Inoue, M, Kigawa, T, Yokoyama, S, RIKEN Structural Genomics/Proteomics Initiative (RSGI) | Deposit date: | 2005-05-17 | Release date: | 2005-11-17 | Last modified: | 2024-05-29 | Method: | SOLUTION NMR | Cite: | Solution structures of the SH2 domain of human protein-tyrosine phosphatase SHP-1 To be Published
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6V7R
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![BU of 6v7r by Molmil](/molmil-images/mine/6v7r) | Crystal structure of K37-acetylated SUMO1 in complex with PIAS-SIM2 | Descriptor: | Protein PIAS, Small ubiquitin-related modifier 1 | Authors: | Lussier-Price, M, Wahba, H.M, Mascle, X.H, Cappadocia, L, Sakaguchi, K, Omichinski, J.G. | Deposit date: | 2019-12-09 | Release date: | 2020-04-01 | Last modified: | 2023-11-15 | Method: | X-RAY DIFFRACTION (1.549 Å) | Cite: | Characterization of a C-Terminal SUMO-Interacting Motif Present in Select PIAS-Family Proteins. Structure, 28, 2020
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6GVK
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![BU of 6gvk by Molmil](/molmil-images/mine/6gvk) | Second pair of Fibronectin type III domains of integrin beta4 (T1663R mutant) bound to the bullous pemphigoid antigen BP230 (BPAG1e) | Descriptor: | Dystonin, GLYCEROL, Integrin beta-4 | Authors: | Manso, J.A, Gomez-Hernandez, M, Alonso-Garcia, N, de Pereda, J.M. | Deposit date: | 2018-06-21 | Release date: | 2019-03-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Integrin alpha 6 beta 4 Recognition of a Linear Motif of Bullous Pemphigoid Antigen BP230 Controls Its Recruitment to Hemidesmosomes. Structure, 27, 2019
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6GVS
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![BU of 6gvs by Molmil](/molmil-images/mine/6gvs) | Engineered glycolyl-CoA reductase comprising 8 mutations with bound NADP+ | Descriptor: | Aldehyde dehydrogenase, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, POTASSIUM ION | Authors: | Zarzycki, J, Trudeau, D, Scheffen, M, Erb, T.J, Tawfik, D.S. | Deposit date: | 2018-06-21 | Release date: | 2018-11-28 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.579 Å) | Cite: | Design and in vitro realization of carbon-conserving photorespiration. Proc. Natl. Acad. Sci. U.S.A., 115, 2018
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6PQV
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![BU of 6pqv by Molmil](/molmil-images/mine/6pqv) | E. coli ATP Synthase State 1e | Descriptor: | ADENOSINE-5'-DIPHOSPHATE, ADENOSINE-5'-TRIPHOSPHATE, ATP synthase epsilon chain, ... | Authors: | Stewart, A.G, Sobti, M, Walshe, J.L. | Deposit date: | 2019-07-10 | Release date: | 2020-06-03 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (3.3 Å) | Cite: | Cryo-EM structures provide insight into how E. coli F1FoATP synthase accommodates symmetry mismatch. Nat Commun, 11, 2020
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1XHL
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![BU of 1xhl by Molmil](/molmil-images/mine/1xhl) | Crystal Structure of putative Tropinone Reductase-II from Caenorhabditis Elegans with Cofactor and Substrate | Descriptor: | 8-METHYL-8-AZABICYCLO[3,2,1]OCTAN-3-ONE, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, Short-chain dehydrogenase/reductase family member (5L265), ... | Authors: | Schormann, N, Karpova, E, Zhou, J, Zhang, Y, Symersky, J, Bunzel, R, Huang, W.-Y, Arabshahi, A, Qiu, S, Luan, C.-H, Gray, R, Carson, M, Tsao, J, Luo, M, Johnson, D, Lu, S, Lin, G, Luo, D, Cao, Z, Li, S, McKInstry, A, Shang, Q, Chen, Y.-J, Bray, T, Nagy, L, DeLucas, L, Southeast Collaboratory for Structural Genomics (SECSG) | Deposit date: | 2004-09-20 | Release date: | 2004-09-28 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | Crystal Structure of putative Tropinone Reductase-II from Caenorhabditis Elegans with Cofactor and Substrate To be Published
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1SHG
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![BU of 1shg by Molmil](/molmil-images/mine/1shg) | CRYSTAL STRUCTURE OF A SRC-HOMOLOGY 3 (SH3) DOMAIN | Descriptor: | ALPHA-SPECTRIN SH3 DOMAIN | Authors: | Noble, M, Pauptit, R, Musacchio, A, Saraste, M, Wierenga, R.K. | Deposit date: | 1993-05-19 | Release date: | 1993-10-31 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Crystal structure of a Src-homology 3 (SH3) domain. Nature, 359, 1992
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6VGW
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![BU of 6vgw by Molmil](/molmil-images/mine/6vgw) | Crystal structure of VidaL intein (selenomethionine variant) | Descriptor: | GLYCEROL, SULFATE ION, VidaL | Authors: | Burton, A.J, Haugbro, M, Parisi, E, Muir, T.W. | Deposit date: | 2020-01-09 | Release date: | 2020-05-27 | Last modified: | 2020-06-17 | Method: | X-RAY DIFFRACTION (1.51 Å) | Cite: | Live-cell protein engineering with an ultra-short split intein. Proc.Natl.Acad.Sci.USA, 117, 2020
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