6NB1
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![BU of 6nb1 by Molmil](/molmil-images/mine/6nb1) | Crystal structure of Escherichia coli ClpP protease complexed with small molecule activator, ACP1-06 | 分子名称: | ATP-dependent Clp protease proteolytic subunit, GLYCEROL, N-{2-[(2-chlorophenyl)sulfanyl]ethyl}-2-methyl-2-{[5-(trifluoromethyl)pyridin-2-yl]sulfonyl}propanamide | 著者 | Mabanglo, M.F, Houry, W.A, Eger, B.T, Bryson, S, Pai, E.F. | 登録日 | 2018-12-06 | 公開日 | 2019-11-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores. Commun Biol, 2, 2019
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6NAY
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5HBZ
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5HF5
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![BU of 5hf5 by Molmil](/molmil-images/mine/5hf5) | Crystal structure of human acetylcholinesterase in complex with paraoxon in the unaged state (predominant acyl loop conformation) | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Franklin, M.F, Rudolph, M.J, Ginter, C, Cassidy, M.S, Cheung, J. | 登録日 | 2016-01-06 | 公開日 | 2016-07-27 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.152 Å) | 主引用文献 | Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface. Proteins, 84, 2016
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6NAW
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5HFA
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![BU of 5hfa by Molmil](/molmil-images/mine/5hfa) | Crystal structure of human acetylcholinesterase in complex with paraoxon and 2-PAM | 分子名称: | 1,2-ETHANEDIOL, 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-[alpha-L-fucopyranose-(1-6)]2-acetamido-2-deoxy-beta-D-glucopyranose, ... | 著者 | Franklin, M.F, Rudolph, M.J, Ginter, C, Cassidy, M.S, Cheung, J. | 登録日 | 2016-01-06 | 公開日 | 2016-06-22 | 最終更新日 | 2023-09-27 | 実験手法 | X-RAY DIFFRACTION (2.201 Å) | 主引用文献 | Structures of paraoxon-inhibited human acetylcholinesterase reveal perturbations of the acyl loop and the dimer interface. Proteins, 84, 2016
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6NRH
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![BU of 6nrh by Molmil](/molmil-images/mine/6nrh) | Crystal Structure of human PARP-1 ART domain bound inhibitor UTT63 | 分子名称: | 3-hydroxy-2-({4-[4-(pyrimidin-2-yl)piperazine-1-carbonyl]phenyl}methyl)-1-benzofuran-7-carboxamide, DIMETHYL SULFOXIDE, Poly [ADP-ribose] polymerase 1, ... | 著者 | Langelier, M.F, Pascal, J.M. | 登録日 | 2019-01-23 | 公開日 | 2019-08-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.5 Å) | 主引用文献 | Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity. J.Med.Chem., 62, 2019
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6NPK
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![BU of 6npk by Molmil](/molmil-images/mine/6npk) | Structure of the TM domain | 分子名称: | Solute carrier family 12 (sodium/potassium/chloride transporter), member 2 | 著者 | Feng, L, Liao, M.F, Orlando, B, Zhang, J.R. | 登録日 | 2019-01-17 | 公開日 | 2019-07-31 | 最終更新日 | 2019-08-28 | 実験手法 | ELECTRON MICROSCOPY (3.6 Å) | 主引用文献 | Structure and mechanism of the cation-chloride cotransporter NKCC1. Nature, 572, 2019
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6NRJ
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![BU of 6nrj by Molmil](/molmil-images/mine/6nrj) | Crystal Structure of human PARP-1 ART domain bound to inhibitor UTT93 | 分子名称: | (2Z)-2-[(4-{[2-(1H-benzimidazol-2-yl)ethyl]carbamoyl}phenyl)methylidene]-3-oxo-2,3-dihydro-1-benzofuran-7-carboxamide, DIMETHYL SULFOXIDE, Poly [ADP-ribose] polymerase 1, ... | 著者 | Langelier, M.F, Pascal, J.M. | 登録日 | 2019-01-23 | 公開日 | 2019-08-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.65 Å) | 主引用文献 | Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity. J.Med.Chem., 62, 2019
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8IWA
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![BU of 8iwa by Molmil](/molmil-images/mine/8iwa) | Crystal structure of Q9PR55 at pH 6.5 | 分子名称: | SULFATE ION, Uncharacterized protein UU089.1 | 著者 | Hsu, M.F, Ko, T.P, Huang, K.F, Chen, Y.R, Huang, J.S, Hsu, S.T.D. | 登録日 | 2023-03-29 | 公開日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.51 Å) | 主引用文献 | Structure, dynamics, and stability of the smallest and most complex 7 1 protein knot. J.Biol.Chem., 300, 2023
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8IWC
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![BU of 8iwc by Molmil](/molmil-images/mine/8iwc) | Crystal structure of Q9PR55 at pH 6.0 | 分子名称: | Uncharacterized protein UU089.1 | 著者 | Hsu, M.F, Ko, T.P, Huang, K.F, Chen, Y.R, Huang, J.S, Hsu, S.T.D. | 登録日 | 2023-03-29 | 公開日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Structure, dynamics, and stability of the smallest and most complex 7 1 protein knot. J.Biol.Chem., 300, 2023
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8IWB
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![BU of 8iwb by Molmil](/molmil-images/mine/8iwb) | Crystal structure of Q9PR55 at pH 7.5 | 分子名称: | Uncharacterized protein UU089.1 | 著者 | Hsu, M.F, Ko, T.P, Huang, K.F, Chen, Y.R, Huang, J.S, Hsu, S.T.D. | 登録日 | 2023-03-29 | 公開日 | 2024-02-07 | 実験手法 | X-RAY DIFFRACTION (2.42 Å) | 主引用文献 | Structure, dynamics, and stability of the smallest and most complex 7 1 protein knot. J.Biol.Chem., 300, 2023
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6NE0
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![BU of 6ne0 by Molmil](/molmil-images/mine/6ne0) | Structure of double-stranded target DNA engaged Csy complex from Pseudomonas aeruginosa (PA-14) | 分子名称: | CRISPR RNA (60-MER), CRISPR target DNA (44-MER), CRISPR-associated endonuclease Cas6/Csy4, ... | 著者 | Chowdhury, S, Rollins, M.F, Carter, J, Golden, S.M, Miettinen, H.M, Santiago-Frangos, A, Faith, D, Lawrence, M.C, Wiedenheft, B, Lander, G.C. | 登録日 | 2018-12-15 | 公開日 | 2018-12-26 | 最終更新日 | 2024-03-13 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Structure Reveals a Mechanism of CRISPR-RNA-Guided Nuclease Recruitment and Anti-CRISPR Viral Mimicry. Mol. Cell, 74, 2019
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6NTU
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6NPJ
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6O1H
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![BU of 6o1h by Molmil](/molmil-images/mine/6o1h) | Tryptophan synthase Q114A mutant in complex with N-(4'-trifluoromethoxybenzenesulfonyl)-2-amino-1-ethylphosphate (F9F) at the enzyme alpha-site, cesium ion at the metal coordination site, and 2-aminophenol quinonoid at the enzyme beta site | 分子名称: | (2E)-2-[({3-hydroxy-2-methyl-5-[(phosphonooxy)methyl]pyridin-4-yl}methyl)imino]-3-[(2-hydroxyphenyl)amino]propanoic acid, 2-({[4-(TRIFLUOROMETHOXY)PHENYL]SULFONYL}AMINO)ETHYL DIHYDROGEN PHOSPHATE, CESIUM ION, ... | 著者 | Hilario, E, Dunn, M.F, Mueller, L.J, Fan, L. | 登録日 | 2019-02-19 | 公開日 | 2020-02-19 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Crystal structure of Salmonella typhimurium Tryptophan Synthase mutant beta-Q114A with 2-({[4-(trifluoromethoxy)phenyl]sulfonyl}amino)ethyl dihydrogen phosphate (F9F) at the alpha-site, Cesium ion at the metal coordination site, and [3-hydroxy-2-methyl-5-phosphonooxymethyl-pyridin-4-ylmethyl]-serine (PLS) at the beta-site. To be Published
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6NAQ
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![BU of 6naq by Molmil](/molmil-images/mine/6naq) | Crystal structure of Neisseria meningitidis ClpP protease in Apo form | 分子名称: | ATP-dependent Clp protease proteolytic subunit, POTASSIUM ION | 著者 | Houry, W.A, Mabanglo, M.F, Pai, E.F, Eger, B.T, Bryson, S. | 登録日 | 2018-12-06 | 公開日 | 2019-11-13 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (2.022 Å) | 主引用文献 | ClpP protease activation results from the reorganization of the electrostatic interaction networks at the entrance pores. Commun Biol, 2, 2019
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6NRG
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![BU of 6nrg by Molmil](/molmil-images/mine/6nrg) | Crystal Structure of human PARP-1 ART domain bound to inhibitor UTT57 | 分子名称: | 2-{[3-fluoro-4-(1H-tetrazol-5-yl)phenyl]methyl}-3-hydroxy-1-benzofuran-7-carboxamide, DIMETHYL SULFOXIDE, Poly [ADP-ribose] polymerase 1, ... | 著者 | Langelier, M.F, Pascal, J.M. | 登録日 | 2019-01-23 | 公開日 | 2019-08-14 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Design and Synthesis of Poly(ADP-ribose) Polymerase Inhibitors: Impact of Adenosine Pocket-Binding Motif Appendage to the 3-Oxo-2,3-dihydrobenzofuran-7-carboxamide on Potency and Selectivity. J.Med.Chem., 62, 2019
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5IOJ
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6NPH
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![BU of 6nph by Molmil](/molmil-images/mine/6nph) | Structure of NKCC1 TM domain | 分子名称: | (2S)-3-(hexadecanoyloxy)-2-[(9Z)-octadec-9-enoyloxy]propyl 2-(trimethylammonio)ethyl phosphate, CHLORIDE ION, POTASSIUM ION, ... | 著者 | Feng, L, Liao, M.F, Orlando, B, Zhang, J.R. | 登録日 | 2019-01-17 | 公開日 | 2019-07-31 | 最終更新日 | 2020-01-29 | 実験手法 | ELECTRON MICROSCOPY (2.9 Å) | 主引用文献 | Structure and mechanism of the cation-chloride cotransporter NKCC1. Nature, 572, 2019
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3C2G
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![BU of 3c2g by Molmil](/molmil-images/mine/3c2g) | Crystal complex of SYS-1/POP-1 at 2.5A resolution | 分子名称: | Pop-1 8-residue peptide, Sys-1 protein | 著者 | Liu, J, Phillips, B.T, Amaya, M.F, Kimble, J, Xu, W. | 登録日 | 2008-01-24 | 公開日 | 2008-05-20 | 最終更新日 | 2017-10-25 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | The C. elegans SYS-1 protein is a bona fide beta-catenin. Dev.Cell, 14, 2008
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8OHN
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![BU of 8ohn by Molmil](/molmil-images/mine/8ohn) | Human Coronavirus HKU1 spike glycoprotein | 分子名称: | 2-acetamido-2-deoxy-beta-D-glucopyranose, 2-acetamido-2-deoxy-beta-D-glucopyranose-(1-4)-2-acetamido-2-deoxy-beta-D-glucopyranose, Spike glycoprotein, ... | 著者 | Pronker, M.F, Hurdiss, D.L. | 登録日 | 2023-03-21 | 公開日 | 2023-08-02 | 最終更新日 | 2023-12-13 | 実験手法 | ELECTRON MICROSCOPY (3.4 Å) | 主引用文献 | Sialoglycan binding triggers spike opening in a human coronavirus. Nature, 624, 2023
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5IHZ
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![BU of 5ihz by Molmil](/molmil-images/mine/5ihz) | Crystal structure of anti-gliadin 1002-1E01 Fab fragment | 分子名称: | 1E01 Fab fragment heavy chain, 1E01 Fab fragment light chain | 著者 | Snir, O, Chen, X, Gidoni, M, du Pre, M.F, Zhao, Y, Steinsbo, O, Lundin, K.E, Yaari, G, Sollid, L.M. | 登録日 | 2016-03-01 | 公開日 | 2017-03-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.64 Å) | 主引用文献 | Stereotyped antibody responses target posttranslationally modified gluten in celiac disease. JCI Insight, 2, 2017
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5IJK
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![BU of 5ijk by Molmil](/molmil-images/mine/5ijk) | Crystal structure of anti-gliadin 1002-1E03 Fab fragment in complex of peptide PLQPEQPFP | 分子名称: | 1E03 Fab fragment heavy chain, 1E03 Fab fragment light chain, SULFATE ION, ... | 著者 | Snir, O, Chen, X, Gidoni, M, du Pre, M.F, Zhao, Y, Steinsbo, O, Lundin, K.E, Yaari, G, Sollid, L.M. | 登録日 | 2016-03-02 | 公開日 | 2017-03-15 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | 主引用文献 | Stereotyped antibody responses target posttranslationally modified gluten in celiac disease. JCI Insight, 2, 2017
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6OFQ
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![BU of 6ofq by Molmil](/molmil-images/mine/6ofq) | ABC transporter-associated periplasmic binding protein DppA from Helicobacter pylori in complex with peptide STSA | 分子名称: | Heme-binding protein A / AI-2 binding protein A, SER-THR-SER-ALA | 著者 | Rahman, M.M, Machuca, M.A, Khan, M.F, Barlow, C.K, Schittenhelm, R.B, Roujeinikova, A. | 登録日 | 2019-03-31 | 公開日 | 2019-08-21 | 最終更新日 | 2023-10-11 | 実験手法 | X-RAY DIFFRACTION (1.45 Å) | 主引用文献 | Molecular Basis of Unexpected Specificity of ABC Transporter-Associated Substrate-Binding Protein DppA from Helicobacter pylori. J.Bacteriol., 201, 2019
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