4XWW
| Crystal structure of RNase J complexed with RNA | 分子名称: | DR2417, GLYCEROL, MANGANESE (II) ION, ... | 著者 | Lu, M, Zhang, H, Xu, Q, Hua, Y, Zhao, Y. | 登録日 | 2015-01-29 | 公開日 | 2015-12-16 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | 主引用文献 | Structural insights into catalysis and dimerization enhanced exonuclease activity of RNase J Nucleic Acids Res., 43, 2015
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4XWT
| Crystal structure of RNase J complexed with UMP | 分子名称: | DR2417, GLYCEROL, MANGANESE (II) ION, ... | 著者 | Lu, M, Zhang, H, Xu, Q, Hua, Y, Zhao, Y. | 登録日 | 2015-01-29 | 公開日 | 2015-12-16 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (2.003 Å) | 主引用文献 | Structural insights into catalysis and dimerization enhanced exonuclease activity of RNase J Nucleic Acids Res., 43, 2015
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6VS0
| protein B | 分子名称: | CHLORAMPHENICOL, Multidrug transporter MdfA, PRASEODYMIUM ION | 著者 | Lu, M, Lu, M.M. | 登録日 | 2020-02-10 | 公開日 | 2020-06-03 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | 主引用文献 | Structure and mechanism of a redesigned multidrug transporter from the Major Facilitator Superfamily. Sci Rep, 10, 2020
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6VS2
| protein D | 分子名称: | LAURYL DIMETHYLAMINE-N-OXIDE, Multidrug transporter MdfA, PRASEODYMIUM ION | 著者 | Lu, M, Lu, M.M. | 登録日 | 2020-02-10 | 公開日 | 2020-06-03 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure and mechanism of a redesigned multidrug transporter from the Major Facilitator Superfamily. Sci Rep, 10, 2020
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6VS1
| protein C | 分子名称: | (3ALPHA,5BETA,12ALPHA)-3,12-DIHYDROXYCHOLAN-24-OIC ACID, Multidrug transporter MdfA, PRASEODYMIUM ION | 著者 | Lu, M, Lu, M.M. | 登録日 | 2020-02-10 | 公開日 | 2020-06-03 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structure and mechanism of a redesigned multidrug transporter from the Major Facilitator Superfamily. Sci Rep, 10, 2020
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6VRZ
| protein A | 分子名称: | CHLORAMPHENICOL, Multidrug transporter MdfA, PRASEODYMIUM ION | 著者 | Lu, M, Lu, M.M. | 登録日 | 2020-02-10 | 公開日 | 2020-06-03 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (2 Å) | 主引用文献 | Structure and mechanism of a redesigned multidrug transporter from the Major Facilitator Superfamily. Sci Rep, 10, 2020
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6X63
| Atomic-Resolution Structure of HIV-1 Capsid Tubes by Magic Angle Spinning NMR | 分子名称: | HIV-1 capsid protein | 著者 | Lu, M, Russell, R.W, Bryer, A, Quinn, C.M, Hou, G, Zhang, H, Schwieters, C.D, Perilla, J.R, Gronenborn, A.M, Polenova, T. | 登録日 | 2020-05-27 | 公開日 | 2020-09-02 | 最終更新日 | 2024-05-15 | 実験手法 | SOLID-STATE NMR | 主引用文献 | Atomic-resolution structure of HIV-1 capsid tubes by magic-angle spinning NMR. Nat.Struct.Mol.Biol., 27, 2020
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1CE9
| HELIX CAPPING IN THE GCN4 LEUCINE ZIPPER | 分子名称: | PROTEIN (GCN4-PMSE) | 著者 | Lu, M, Shu, W, Ji, H, Spek, E, Wang, L.-Y, Kallenbach, N.R. | 登録日 | 1999-03-18 | 公開日 | 1999-03-25 | 最終更新日 | 2023-08-09 | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | 主引用文献 | Helix capping in the GCN4 leucine zipper. J.Mol.Biol., 288, 1999
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1DFU
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7CUU
| Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with MG132 | 分子名称: | 3C protein, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Lu, M, Yang, H.T, Wang, Z.Y, Zhao, Y, Xing, Y.F. | 登録日 | 2020-08-24 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.68 Å) | 主引用文献 | Identification of proteasome and caspase inhibitors targeting SARS-CoV-2 M pro . Signal Transduct Target Ther, 6, 2021
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7CUT
| Crystal structure of the SARS-CoV-2 (COVID-19) main protease in complex with Z-VAD-FMK | 分子名称: | 3C protein, DIMETHYL SULFOXIDE, GLYCEROL, ... | 著者 | Lu, M, Yang, H.T, Wang, Z.Y, Zhao, Y, Xing, Y.F. | 登録日 | 2020-08-24 | 公開日 | 2021-06-23 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.82 Å) | 主引用文献 | Identification of proteasome and caspase inhibitors targeting SARS-CoV-2 M pro . Signal Transduct Target Ther, 6, 2021
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3H90
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3HFH
| Crystal structure of tandem FF domains | 分子名称: | Transcription elongation regulator 1 | 著者 | Lu, M, Yang, J, Ren, Z, Subir, S, Bedford, M.T, Jacobson, R.H, McMurray, J.S, Chen, X. | 登録日 | 2009-05-11 | 公開日 | 2009-08-18 | 最終更新日 | 2017-11-01 | 実験手法 | X-RAY DIFFRACTION (2.703 Å) | 主引用文献 | Crystal Structure of the Three Tandem FF Domains of the Transcription Elongation Regulator CA150. J.Mol.Biol., 393, 2009
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8I4S
| the complex structure of SARS-CoV-2 Mpro with D8 | 分子名称: | 3-(4-fluoranyl-3-methyl-phenyl)-2-(2-methylpropyl)-5,6,7-tris(oxidanyl)quinazolin-4-one, ORF1a polyprotein | 著者 | Lu, M. | 登録日 | 2023-01-21 | 公開日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (2.2 Å) | 主引用文献 | Discovery of quinazolin-4-one-based non-covalent inhibitors targeting the severe acute respiratory syndrome coronavirus 2 main protease (SARS-CoV-2 M pro ). Eur.J.Med.Chem., 257, 2023
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5C6N
| protein A | 分子名称: | BH2163 protein | 著者 | Lu, M. | 登録日 | 2015-06-23 | 公開日 | 2015-09-23 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis for the blockade of MATE multidrug efflux pumps. Nat Commun, 6, 2015
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5C6P
| protein C | 分子名称: | (2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile, protein C, protein D | 著者 | Lu, M. | 登録日 | 2015-06-23 | 公開日 | 2015-09-23 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis for the blockade of MATE multidrug efflux pumps. Nat Commun, 6, 2015
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5C6O
| protein B | 分子名称: | (2S)-2-(3,4-dimethoxyphenyl)-5-{[2-(3,4-dimethoxyphenyl)ethyl](methyl)amino}-2-(propan-2-yl)pentanenitrile, BH2163 protein | 著者 | Lu, M. | 登録日 | 2015-06-23 | 公開日 | 2015-09-23 | 最終更新日 | 2024-03-06 | 実験手法 | X-RAY DIFFRACTION (3 Å) | 主引用文献 | Structural basis for the blockade of MATE multidrug efflux pumps. Nat Commun, 6, 2015
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7XX4
| designed glycosyltransferase | 分子名称: | Oleandomycin glycosyltransferase, URIDINE-5'-DIPHOSPHATE-GLUCOSE | 著者 | Lu, M, Wu, X. | 登録日 | 2022-05-28 | 公開日 | 2023-06-14 | 最終更新日 | 2023-12-27 | 実験手法 | X-RAY DIFFRACTION (2.43 Å) | 主引用文献 | Design of a chimeric glycosyltransferase OleD for the site-specific O-monoglycosylation of 3-hydroxypyridine in nosiheptide. Microb Biotechnol, 16, 2023
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4E13
| Substrate-directed dual catalysis of dicarbonyl compounds by diketoreductase | 分子名称: | Diketoreductase, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Lu, M, White, M.A, Huang, Y, Wu, X, Liu, N, Cheng, X, Chen, Y. | 登録日 | 2012-03-05 | 公開日 | 2012-11-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.08 Å) | 主引用文献 | Dual catalysis mode for the dicarbonyl reduction catalyzed by diketoreductase Chem.Commun.(Camb.), 48, 2012
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4DYD
| Substrate-directed dual catalysis of dicarbonyl compounds by diketoreductase | 分子名称: | Diketoreductase, GLYCEROL, NICOTINAMIDE-ADENINE-DINUCLEOTIDE, ... | 著者 | Lu, M, White, M.A, Huang, Y, Wu, X, Liu, N, Cheng, X, Chen, Y. | 登録日 | 2012-02-28 | 公開日 | 2012-11-14 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | 主引用文献 | Dual catalysis mode for the dicarbonyl reduction catalyzed by diketoreductase Chem.Commun.(Camb.), 48, 2012
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4E12
| Substrate-directed dual catalysis of dicarbonyl compounds by diketoreductase | 分子名称: | Diketoreductase, GLYCEROL, PENTAETHYLENE GLYCOL, ... | 著者 | Lu, M, White, M.A, Huang, Y, Wu, X, Liu, N, Cheng, X, Chen, Y. | 登録日 | 2012-03-05 | 公開日 | 2012-11-14 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (1.93 Å) | 主引用文献 | Dual catalysis mode for the dicarbonyl reduction catalyzed by diketoreductase Chem.Commun.(Camb.), 48, 2012
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6WAP
| Atomic-Resolution Structure of HIV-1 Capsid Tubes by Magic Angle Spinning NMR | 分子名称: | HIV-1 capsid protein | 著者 | Lu, M, Russell, R.W, Bryer, A, Quinn, C.M, Hou, G, Zhang, H, Schwieters, C.D, Perilla, J.R, Gronenborn, A.M, Polenova, T. | 登録日 | 2020-03-25 | 公開日 | 2020-09-02 | 最終更新日 | 2024-05-15 | 実験手法 | SOLID-STATE NMR | 主引用文献 | Atomic-resolution structure of HIV-1 capsid tubes by magic-angle spinning NMR. Nat.Struct.Mol.Biol., 27, 2020
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4LZ6
| Structure of MATE multidrug transporter DinF-BH | 分子名称: | BH2163 protein | 著者 | Lu, M, Radchenko, M, Symersky, J, Nie, R, Guo, Y. | 登録日 | 2013-07-31 | 公開日 | 2013-10-23 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.2 Å) | 主引用文献 | Structural insights into H(+)-coupled multidrug extrusion by a MATE transporter Nat.Struct.Mol.Biol., 20, 2013
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4LZ9
| Structure of MATE multidrug transporter DinF-BH in complex with R6G | 分子名称: | BH2163 protein, RHODAMINE 6G | 著者 | Lu, M, Radchenko, M, Symersky, J, Nie, R, Guo, Y. | 登録日 | 2013-07-31 | 公開日 | 2013-10-23 | 最終更新日 | 2024-03-20 | 実験手法 | X-RAY DIFFRACTION (3.7 Å) | 主引用文献 | Structural insights into H(+)-coupled multidrug extrusion by a MATE transporter Nat.Struct.Mol.Biol., 20, 2013
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4HUN
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