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PDB: 64 件
2HTF
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The solution structure of the BRCT domain from human polymerase reveals homology with the TdT BRCT domain
分子名称: DNA polymerase mu
著者DeRose, E.F, Clarkson, M.W, Gilmore, S.A, Ramsden, D.A, Mueller, G.A, London, R.E, Lee, A.L.
登録日2006-07-25
公開日2007-02-27
最終更新日2024-05-29
実験手法SOLUTION NMR
主引用文献Solution structure of polymerase mu's BRCT Domain reveals an element essential for its role in nonhomologous end joining.
Biochemistry, 46, 2007
5UIO
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structure of DHFR with bound DAP, p-ABG and NADP
分子名称: BETA-MERCAPTOETHANOL, Dihydrofolate reductase, FORMIC ACID, ...
著者Pedersen, L.C, London, R.E.
登録日2017-01-14
公開日2017-11-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.929 Å)
主引用文献A Structural Basis for Biguanide Activity.
Biochemistry, 56, 2017
2O3B
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Crystal structure complex of Nuclease A (NucA) with intra-cellular inhibitor NuiA
分子名称: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, MAGNESIUM ION, NICKEL (II) ION, ...
著者Ghosh, M, Meiss, G, Pingoud, A.M, London, R.E, Pedersen, L.C.
登録日2006-12-01
公開日2006-12-19
最終更新日2023-08-30
実験手法X-RAY DIFFRACTION (2.3 Å)
主引用文献The nuclease a-inhibitor complex is characterized by a novel metal ion bridge.
J.Biol.Chem., 282, 2007
5W4G
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Importin binding to NLS peptide of DNA polymerase lambda
分子名称: DNA polymerase lambda, GLYCEROL, Importin subunit alpha-1, ...
著者Pedersen, L.C, London, R.E.
登録日2017-06-10
公開日2018-06-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.038 Å)
主引用文献Structure of Importin with bound NLS from DNA polymerase lambda
To Be Published
1NZP
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Solution Structure of the Lyase Domain of Human DNA Polymerase Lambda
分子名称: DNA polymerase lambda
著者DeRose, E.F, Kirby, T.W, Mueller, G.A, Bebenek, K, Garcia-Diaz, M, Blanco, L, Kunkel, T.A, London, R.E.
登録日2003-02-19
公開日2003-08-05
最終更新日2024-05-22
実験手法SOLUTION NMR
主引用文献Solution Structure of the Lyase Domain of Human DNA Polymerase Lambda
Biochemistry, 42, 2003
1O1W
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SOLUTION STRUCTURE OF THE RNASE H DOMAIN OF THE HIV-1 REVERSE TRANSCRIPTASE IN THE PRESENCE OF MAGNESIUM
分子名称: RIBONUCLEASE H
著者Pari, K, Mueller, G.A, Derose, E.F, Kirby, T.W, London, R.E.
登録日2003-02-12
公開日2003-02-18
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献Solution Structure of the Rnase H Domain of the HIV-1 Reverse Transcriptase in the Presence of Magnesium
Biochemistry, 42, 2003
1QVX
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SOLUTION STRUCTURE OF THE FAT DOMAIN OF FOCAL ADHESION KINASE
分子名称: Focal adhesion kinase 1
著者Gao, G, Prutzman, K.C, King, M.L, DeRose, E.F, London, R.E, Schaller, M.D, Campbell, S.L.
登録日2003-08-29
公開日2004-03-02
最終更新日2024-05-08
実験手法SOLUTION NMR
主引用文献NMR Solution Structure of the Focal Adhesion Targeting Domain of Focal Adhesion Kinase in Complex with a Paxillin LD Peptide: EVIDENCE FOR A TWO-SITE BINDING MODEL.
J.Biol.Chem., 279, 2004
5UII
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structure of DHFR with bound buformin and NADP
分子名称: CALCIUM ION, Dihydrofolate reductase, N-butyl-N'-(diaminomethylidene)guanidine, ...
著者Pedersen, L.C, London, R.E.
登録日2017-01-14
公開日2018-01-31
最終更新日2023-10-25
実験手法X-RAY DIFFRACTION (1.351 Å)
主引用文献A Structural Basis for Biguanide Activity.
Biochemistry, 56, 2017
5UIH
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structure of DHFR with bound phenformin and NADP
分子名称: 1,2-ETHANEDIOL, BETA-MERCAPTOETHANOL, Dihydrofolate reductase, ...
著者Pedersen, L.C, London, R.E.
登録日2017-01-14
公開日2017-11-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.647 Å)
主引用文献A Structural Basis for Biguanide Activity.
Biochemistry, 56, 2017
5W4F
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Importin binding to pol Mu NLS peptide
分子名称: DNA-directed DNA/RNA polymerase mu, GLYCEROL, Importin subunit alpha-1
著者Pedersen, L.C, London, R.E.
登録日2017-06-10
公開日2018-06-13
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.984 Å)
主引用文献Variations in nuclear localization strategies among pol X family enzymes.
Traffic, 2018
5UIP
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structure of DHFR with bound DAP, p-ABG and NADP
分子名称: Dihydrofolate reductase, N-(4-aminobenzene-1-carbonyl)-L-glutamic acid, NADP NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
著者Pedersen, L.C, London, R.E.
登録日2017-01-14
公開日2017-11-22
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.9 Å)
主引用文献A Structural Basis for Biguanide Activity.
Biochemistry, 56, 2017
1J57
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NuiA
分子名称: NuiA
著者Kirby, T.W, Mueller, G.A, DeRose, E.F, Lebetkin, M.S, Meiss, G, Pingoud, A, London, R.E.
登録日2002-01-17
公開日2002-12-04
最終更新日2023-12-27
実験手法SOLUTION NMR
主引用文献The Nuclease A Inhibitor represents a new variation of the rare PR-1 fold.
J.Mol.Biol., 320, 2002
5W7Y
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Crystal Structure of FHA domain of human APLF in complex with XRCC1 monophosphorylated mutated peptide
分子名称: Aprataxin and PNK-like factor, DNA repair protein XRCC1
著者Pedersen, L.C, Kim, K, London, R.E.
登録日2017-06-21
公開日2018-05-02
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (2.1 Å)
主引用文献Characterization of the APLF FHA-XRCC1 phosphopeptide interaction and its structural and functional implications.
Nucleic Acids Res., 45, 2017
5W7W
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Crystal Structure of FHA domain of human APLF
分子名称: Aprataxin and PNK-like factor, FORMIC ACID, SODIUM ION
著者Pedersen, L.C, Kim, K, London, R.E.
登録日2017-06-21
公開日2018-05-02
最終更新日2023-10-04
実験手法X-RAY DIFFRACTION (1.348 Å)
主引用文献Characterization of the APLF FHA-XRCC1 phosphopeptide interaction and its structural and functional implications.
Nucleic Acids Res., 45, 2017
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