6RFP
 
 | | ERK2 MAP kinase with mutations at Helix-G | | Descriptor: | Mitogen-activated protein kinase 1 | | Authors: | Livnah, O, Eitan-Wexler, M. | | Deposit date: | 2019-04-16 | | Release date: | 2020-05-13 | | Last modified: | 2024-01-24 | | Method: | X-RAY DIFFRACTION (1.74 Å) | | Cite: | The bacterial metalloprotease NleD selectively cleaves mitogen-activated protein kinases that have high flexibility in their activation loop.
J.Biol.Chem., 295, 2020
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1LDQ
 | | avidin-homobiotin complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Avidin, HOMOBIOTIN | | Authors: | Pazy, Y, Kulik, T, Bayer, E.A, Wilchek, M, Livnah, O. | | Deposit date: | 2002-04-09 | | Release date: | 2002-11-06 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.7 Å) | | Cite: | Ligand exchange between proteins: exchange of biotin and biotin derivatives between avidin and streptavidin
J.Biol.Chem., 277, 2002
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1NQN
 | | Structure of Avm-W110K (W110K mutant of avidin) | | Descriptor: | Avidin | | Authors: | Pazy, Y, Eisenberg-Domovich, Y, Laitinen, O.H, Kulomaa, M.S, Bayer, E.A, Wilchek, M, Livnah, O. | | Deposit date: | 2003-01-22 | | Release date: | 2003-07-15 | | Last modified: | 2021-10-27 | | Method: | X-RAY DIFFRACTION (1.8 Å) | | Cite: | Dimer-Tetramer Transition between Solution and Crystalline States of Streptavidin and Avidin Mutants.
J.Bacteriol., 185, 2003
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1NQM
 | | Structure of Savm-W120K, streptavidin mutant | | Descriptor: | BIOTIN, Streptavidin | | Authors: | Pazy, Y, Eisenberg-Domovich, Y, Laitinen, O.H, Kulomaa, M.S, Bayer, E.A, Wilchek, M, Livnah, O. | | Deposit date: | 2003-01-22 | | Release date: | 2003-07-15 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Dimer-Tetramer Transition between Solution and Crystalline States of Streptavidin and Avidin Mutants.
J.Bacteriol., 185, 2003
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1Y53
 | | Crystal structure of bacterial expressed avidin related protein 4 (AVR4) C122S | | Descriptor: | Avidin-related protein 4/5, FORMIC ACID | | Authors: | Eisenberg-Domovich, Y, Hytonen, V.P, Wilchek, M, Bayer, E.A, Kulomaa, M.S, Livnah, O. | | Deposit date: | 2004-12-02 | | Release date: | 2005-05-24 | | Last modified: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (1.2 Å) | | Cite: | High-resolution crystal structure of an avidin-related protein: insight into high-affinity biotin binding and protein stability.
Acta Crystallogr.,Sect.D, 61, 2005
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1Y52
 | | structure of insect cell (Baculovirus) expressed AVR4 (C122S)-biotin complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Avidin-related protein 4/5, BIOTIN | | Authors: | Eisenberg-Domovich, Y, Hytonen, V.P, Wilchek, M, Bayer, E.A, Kulomaa, M.S, Livnah, O. | | Deposit date: | 2004-12-02 | | Release date: | 2005-05-24 | | Last modified: | 2024-01-03 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | High-resolution crystal structure of an avidin-related protein: insight into high-affinity biotin binding and protein stability.
Acta Crystallogr.,Sect.D, 61, 2005
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1Y55
 | | Crystal structure of the C122S mutant of E. Coli expressed avidin related protein 4 (AVR4)-biotin complex | | Descriptor: | Avidin-related protein 4/5, BIOTIN, FORMIC ACID | | Authors: | Eisenberg-Domovich, Y, Hytonen, V.P, Wilchek, M, Bayer, E.A, Kulomaa, M.S, Livnah, O. | | Deposit date: | 2004-12-02 | | Release date: | 2005-05-24 | | Last modified: | 2021-11-10 | | Method: | X-RAY DIFFRACTION (1 Å) | | Cite: | High-resolution crystal structure of an avidin-related protein: insight into high-affinity biotin binding and protein stability.
Acta Crystallogr.,Sect.D, 61, 2005
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1RXK
 | | crystal structure of streptavidin mutant (M3) a combination of M1+M2 | | Descriptor: | 5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID (4-NITRO-PHENYL)-AMIDE, Streptavidin | | Authors: | Eisenberg-Domovich, Y, Pazy, Y, Nir, O, Raboy, B, Bayer, E.A, Wilchek, M, Livnah, O. | | Deposit date: | 2003-12-18 | | Release date: | 2004-05-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.7 Å) | | Cite: | Structural elements responsible for conversion of streptavidin to a pseudoenzyme.
Proc.Natl.Acad.Sci.USA, 101, 2004
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1RXH
 | | Crystal structure of streptavidin mutant L124R (M1) complexed with biotinyl p-nitroanilide (BNI) | | Descriptor: | 5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID (4-NITRO-PHENYL)-AMIDE, Streptavidin | | Authors: | Eisenberg-Domovich, Y, Pazy, Y, Nir, O, Raboy, B, Bayer, E.A, Wilchek, M, Livnah, O. | | Deposit date: | 2003-12-18 | | Release date: | 2004-05-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Structural elements responsible for conversion of streptavidin to a pseudoenzyme
Proc.Natl.Acad.Sci.USA, 101, 2004
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1RFK
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1RXJ
 | | Crystal structure of streptavidin mutant (M2) where the L3,4 loop was replace by that of avidin | | Descriptor: | 5-(2-OXO-HEXAHYDRO-THIENO[3,4-D]IMIDAZOL-6-YL)-PENTANOIC ACID (4-NITRO-PHENYL)-AMIDE, Streptavidin | | Authors: | Eisenberg-Domovich, Y, Pazy, Y, Nir, O, Raboy, B, Bayer, E.A, Wilchek, M, Livnah, O. | | Deposit date: | 2003-12-18 | | Release date: | 2004-05-11 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.14 Å) | | Cite: | Structural elements responsible for conversion of streptavidin to a pseudoenzyme
Proc.Natl.Acad.Sci.USA, 101, 2004
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4OOA
 | | CRYSTAL STRUCTURE of NAF1 (MINER1): H114C THE REDOX-ACTIVE 2FE-2S PROTEIN | | Descriptor: | CDGSH iron-sulfur domain-containing protein 2, FE2/S2 (INORGANIC) CLUSTER | | Authors: | Tamir, S, Eisenberg-Domovich, Y, Conlan, A.R, Stofleth, J.T, Lipper, C.H, Paddock, M.L, Mittler, R, Jennings, P.A, Livnah, O, Nechushtai, R. | | Deposit date: | 2014-01-31 | | Release date: | 2014-07-02 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.58 Å) | | Cite: | A point mutation in the [2Fe-2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor properties.
Acta Crystallogr.,Sect.D, 70, 2014
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4OO7
 | | THE 1.55A CRYSTAL STRUCTURE of NAF1 (MINER1): THE REDOX-ACTIVE 2FE-2S PROTEIN | | Descriptor: | CDGSH iron-sulfur domain-containing protein 2, FE2/S2 (INORGANIC) CLUSTER | | Authors: | Tamir, S, Eisenberg-Domovich, Y, Colman, A.R, Stofleth, J.T, Lipper, C.H, Paddock, M.L, Jenning, P.A, Livnah, O, Nechushtai, R. | | Deposit date: | 2014-01-31 | | Release date: | 2014-07-02 | | Last modified: | 2024-02-28 | | Method: | X-RAY DIFFRACTION (1.65 Å) | | Cite: | A point mutation in the [2Fe-2S] cluster binding region of the NAF-1 protein (H114C) dramatically hinders the cluster donor properties.
Acta Crystallogr.,Sect.D, 70, 2014
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1LDO
 | | avidin-norbioitn complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, NORBIOTIN, avidin | | Authors: | Pazy, Y, Kulik, T, Bayer, E.A, Wilchek, M, Livnah, O. | | Deposit date: | 2002-04-09 | | Release date: | 2002-11-06 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Ligand exchange between proteins: exchange of biotin and biotin derivatives between avidin and streptavidin
J.Biol.Chem., 277, 2002
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1LEL
 | | The avidin BCAP complex | | Descriptor: | 2-acetamido-2-deoxy-beta-D-glucopyranose, Avidin, E-AMINO BIOTINYL CAPROIC ACID | | Authors: | Pazy, Y, Kulik, T, Bayer, E.A, Wilchek, M, Livnah, O. | | Deposit date: | 2002-04-10 | | Release date: | 2002-11-06 | | Last modified: | 2020-07-29 | | Method: | X-RAY DIFFRACTION (2.9 Å) | | Cite: | Ligand exchange between proteins: exchange of biotin and biotin derivatives between avidin and streptavidin
J.Biol.Chem., 277, 2002
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7P8Y
 | | Short wilavidin apo form | | Descriptor: | DI(HYDROXYETHYL)ETHER, HEXAETHYLENE GLYCOL, PENTAETHYLENE GLYCOL, ... | | Authors: | Avraham, O, Livnah, O. | | Deposit date: | 2021-07-23 | | Release date: | 2021-11-17 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.18 Å) | | Cite: | Wilavidin - a novel member of the avidin family that forms unique biotin-binding hexamers.
Febs J., 289, 2022
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7P8Z
 | | Short wilavidin biotin complex | | Descriptor: | 1,2-ETHANEDIOL, 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, BIOTIN, ... | | Authors: | Avraham, O, Livnah, O. | | Deposit date: | 2021-07-23 | | Release date: | 2021-11-17 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.67 Å) | | Cite: | Wilavidin - a novel member of the avidin family that forms unique biotin-binding hexamers.
Febs J., 289, 2022
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7OUQ
 | | wilavidin biotin complex | | Descriptor: | BIOTIN, GLYCEROL, wilavidin | | Authors: | Avraham, O, Livnah, O. | | Deposit date: | 2021-06-13 | | Release date: | 2021-11-17 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (2.63 Å) | | Cite: | Wilavidin - a novel member of the avidin family that forms unique biotin-binding hexamers.
Febs J., 289, 2022
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7OUR
 | | Wilavidin apo form (P1 form) | | Descriptor: | wilavidin | | Authors: | Avraham, O, Livnah, O. | | Deposit date: | 2021-06-13 | | Release date: | 2021-11-17 | | Last modified: | 2024-01-31 | | Method: | X-RAY DIFFRACTION (1.95 Å) | | Cite: | Wilavidin - a novel member of the avidin family that forms unique biotin-binding hexamers.
Febs J., 289, 2022
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2NPQ
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2FSM
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2FST
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2FSO
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2FSL
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6QE7
 | | anti-sigma factor domain-containing protein | | Descriptor: | Anti-sigma-I factor RsgI3, CALCIUM ION | | Authors: | Voronov, M, Livnah, O, Bayer, E.A. | | Deposit date: | 2019-01-07 | | Release date: | 2019-06-12 | | Last modified: | 2024-05-01 | | Method: | X-RAY DIFFRACTION (2.06 Å) | | Cite: | Distinctive ligand-binding specificities of tandem PA14 biomass-sensory elements from Clostridium thermocellum and Clostridium clariflavum.
Proteins, 87, 2019
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