5WWR
 
 | | Crystal structure of human NSun6/tRNA/SFG | | 分子名称: | Putative methyltransferase NSUN6, SINEFUNGIN, tRNA | | 著者 | Liu, R.J, Long, T, Wang, E.D. | | 登録日 | 2017-01-04 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.096 Å) | | 主引用文献 | Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6
Nucleic Acids Res., 45, 2017
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5WWT
 | | Crystal structure of human NSun6/tRNA | | 分子名称: | Putative methyltransferase NSUN6, tRNA | | 著者 | Liu, R.J, Long, T, Wang, E.D. | | 登録日 | 2017-01-04 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (3.197 Å) | | 主引用文献 | Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6
Nucleic Acids Res., 45, 2017
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5WWQ
 | | Crystal structure of human NSun6 | | 分子名称: | Putative methyltransferase NSUN6 | | 著者 | Liu, R.J, Long, T, Wang, E.D. | | 登録日 | 2017-01-04 | | 公開日 | 2017-06-28 | | 最終更新日 | 2023-11-22 | | 実験手法 | X-RAY DIFFRACTION (2.815 Å) | | 主引用文献 | Structural basis for substrate binding and catalytic mechanism of a human RNA:m5C methyltransferase NSun6
Nucleic Acids Res., 45, 2017
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7BZJ
 | | The Discovery of Benzhydrol-Oxaborole Hybrid Derivatives as Leucyl-tRNA Synthetase Inhibitors | | 分子名称: | Leucine--tRNA ligase, [(1~{R},5~{R},6~{S},8~{R})-8-(6-aminopurin-9-yl)-4'-[(~{R})-oxidanyl-[4-(2-oxidanylidenepropylsulfanyl)phenyl]methyl]spiro[2,4,7-trioxa-3-boranuidabicyclo[3.3.0]octane-3,7'-7-boranuidabicyclo[4.3.0]nona-1(6),2,4-triene]-6-yl]methoxy-tris(oxidanyl)phosphanium | | 著者 | Liu, R.J, Li, H, Wang, E.D, Zhou, H. | | 登録日 | 2020-04-28 | | 公開日 | 2020-12-09 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Discovery of benzhydrol-oxaborole derivatives as Streptococcus pneumoniae leucyl-tRNA synthetase inhibitors.
Bioorg.Med.Chem., 29, 2021
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4XBO
 | | Crystal structure of full length E.coli TrmJ in complex with SAH | | 分子名称: | S-ADENOSYL-L-HOMOCYSTEINE, tRNA (cytidine/uridine-2'-O-)-methyltransferase TrmJ | | 著者 | Liu, R.J, Long, T, Zhou, M, Wang, E.D. | | 登録日 | 2014-12-17 | | 公開日 | 2015-12-23 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2.6 Å) | | 主引用文献 | tRNA recognition by a bacterial tRNA Xm32 modification enzyme from the SPOUT methyltransferase superfamily
Nucleic Acids Res., 43, 2015
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1XZ3
 | | Complex of apoferritin with isoflurane | | 分子名称: | 1-CHLORO-2,2,2-TRIFLUOROETHYL DIFLUOROMETHYL ETHER, CADMIUM ION, Ferritin light chain | | 著者 | Liu, R, Loll, P.J, Eckenhoff, R.G. | | 登録日 | 2004-11-11 | | 公開日 | 2005-05-10 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural basis for high-affinity volatile anesthetic binding in a natural 4-helix bundle protein.
Faseb J., 19, 2005
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1XZ1
 | | Complex of halothane with apoferritin | | 分子名称: | 2-BROMO-2-CHLORO-1,1,1-TRIFLUOROETHANE, CADMIUM ION, Ferritin light chain | | 著者 | Liu, R, Loll, P.J, Eckenhoff, R.G. | | 登録日 | 2004-11-11 | | 公開日 | 2005-05-10 | | 最終更新日 | 2023-08-23 | | 実験手法 | X-RAY DIFFRACTION (1.75 Å) | | 主引用文献 | Structural basis for high-affinity volatile anesthetic binding in a natural 4-helix bundle protein.
Faseb J., 19, 2005
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1QS5
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1QSB
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1QTH
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1QTC
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1QTB
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1QS9
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1QTD
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3NDP
 | | Crystal structure of human AK4(L171P) | | 分子名称: | Adenylate kinase isoenzyme 4, SULFATE ION | | 著者 | Liu, R, Wang, Y, Wei, Z, Gong, W. | | 登録日 | 2010-06-07 | | 公開日 | 2010-06-23 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Crystal structure of human adenylate kinase 4 (L171P) suggests the role of hinge region in protein domain motion
Biochem.Biophys.Res.Commun., 379, 2009
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6LR6
 | | The crystal structure of human cytoplasmic LRS | | 分子名称: | 4-Chloro-3-aminomethyl-7-[ethoxy]-3H-benzo[C][1,2]oxaborol-1-ol modified adenosine, 5'-O-(L-leucylsulfamoyl)adenosine, Leucine--tRNA ligase, ... | | 著者 | Liu, R.J, Long, T, Li, H, Li, J, Zhao, J.H, Lin, J.Z, Palencia, A, Wang, M.Z, Cusack, S, Wang, E.D. | | 登録日 | 2020-01-15 | | 公開日 | 2020-03-25 | | 最終更新日 | 2023-11-29 | | 実験手法 | X-RAY DIFFRACTION (3.009 Å) | | 主引用文献 | Molecular basis of the multifaceted functions of human leucyl-tRNA synthetase in protein synthesis and beyond.
Nucleic Acids Res., 48, 2020
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4JAL
 | | Crystal structure of tRNA (Um34/Cm34) methyltransferase TrmL from Escherichia coli with SAH | | 分子名称: | 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, S-ADENOSYL-L-HOMOCYSTEINE, ... | | 著者 | Liu, R.J, Zhou, M, Wang, E.D. | | 登録日 | 2013-02-18 | | 公開日 | 2013-07-31 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | The tRNA recognition mechanism of the minimalist SPOUT methyltransferase, TrmL
Nucleic Acids Res., 41, 2013
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3PZ0
 | | The crystal structure of AaLeuRS-CP1 | | 分子名称: | CALCIUM ION, Leucyl-tRNA synthetase subunit alpha | | 著者 | Liu, R.J, Wang, E.D. | | 登録日 | 2010-12-13 | | 公開日 | 2011-08-24 | | 最終更新日 | 2024-10-09 | | 実験手法 | X-RAY DIFFRACTION (2.4 Å) | | 主引用文献 | Peripheral insertion modulates the editing activity of the isolated CP1 domain of leucyl-tRNA synthetase
Biochem.J., 440, 2011
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4JAK
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3PZ5
 | | The crystal structure of AaLeuRS-CP1-D20 | | 分子名称: | Leucyl-tRNA synthetase subunit alpha | | 著者 | Liu, R.J, Wang, E.D. | | 登録日 | 2010-12-14 | | 公開日 | 2011-08-24 | | 最終更新日 | 2023-11-01 | | 実験手法 | X-RAY DIFFRACTION (2.5 Å) | | 主引用文献 | Peripheral insertion modulates the editing activity of the isolated CP1 domain of leucyl-tRNA synthetase
Biochem.J., 440, 2011
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3PZ6
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3U90
 | | apoferritin: complex with SDS | | 分子名称: | CADMIUM ION, DODECYL SULFATE, Ferritin light chain | | 著者 | Liu, R, Bu, W, Xi, J, Mortazavi, S.R, Cheung-Lau, J.C, Dmochowski, I.J, Loll, P.J. | | 登録日 | 2011-10-17 | | 公開日 | 2012-04-25 | | 最終更新日 | 2023-09-13 | | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | | 主引用文献 | Beyond the detergent effect: a binding site for sodium dodecyl sulfate (SDS) in mammalian apoferritin.
Acta Crystallogr.,Sect.D, 68, 2012
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5YXI
 | | Designed protein dRafX6 | | 分子名称: | Designed protein dRafX6 | | 著者 | Liu, R. | | 登録日 | 2017-12-05 | | 公開日 | 2018-12-05 | | 最終更新日 | 2024-05-15 | | 実験手法 | SOLUTION NMR | | 主引用文献 | De novo sequence redesign of a functional Ras-binding domain globally inverted the surface charge distribution and led to extreme thermostability.
Biotechnol.Bioeng., 118, 2021
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6LQE
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6LQF
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