5BZO
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5BZG
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5BZL
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5BZQ
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5BZS
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5BZJ
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5BZN
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5BZF
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5BZK
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5BZR
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5BZE
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5BZM
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5BZT
| Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule | 分子名称: | 2-(1,3-dimethoxypropan-2-yl)-1,2,3,4-tetrahydroisoquinolin-8-amine, CD44 antigen, DIMETHYL SULFOXIDE, ... | 著者 | Liu, L.K, Finzel, B.C. | 登録日 | 2015-06-11 | 公開日 | 2016-06-29 | 実験手法 | X-RAY DIFFRACTION (1.25 Å) | 主引用文献 | Crystal structure of the murine cd44 hyaluronan binding domain complex with a small molecule To Be Published
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4MO7
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5WQE
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4MXM
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2LQ6
| Solution structure of BRD1 PHD2 finger | 分子名称: | Bromodomain-containing protein 1, ZINC ION | 著者 | Liu, L, Wu, J. | 登録日 | 2012-02-25 | 公開日 | 2012-10-24 | 最終更新日 | 2024-05-01 | 実験手法 | SOLUTION NMR | 主引用文献 | Solution structure of an atypical PHD finger in BRPF2 and its interaction with DNA J.Struct.Biol., 180, 2012
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5WTJ
| Crystal structure of an endonuclease | 分子名称: | CRISPR-associated endoribonuclease C2c2 | 著者 | Liu, L, Wang, Y. | 登録日 | 2016-12-13 | 公開日 | 2017-02-08 | 最終更新日 | 2017-08-30 | 実験手法 | X-RAY DIFFRACTION (3.503 Å) | 主引用文献 | Two Distant Catalytic Sites Are Responsible for C2c2 RNase Activities Cell, 168, 2017
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7F0M
| Crystal Structure of human Pin1 complexed with a potent covalent inhibitor | 分子名称: | 3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL, 8-(2-chloranylethanoyl)-4-[(5-naphthalen-1-ylfuran-2-yl)methyl]-1-thia-4,8-diazaspiro[4.5]decan-3-one, Peptidyl-prolyl cis-trans isomerase NIMA-interacting 1 | 著者 | Liu, L, Li, J. | 登録日 | 2021-06-05 | 公開日 | 2022-02-16 | 最終更新日 | 2023-11-29 | 実験手法 | X-RAY DIFFRACTION (1.9 Å) | 主引用文献 | Computational and Structure-Based Development of High Potent Cell-Active Covalent Inhibitor Targeting the Peptidyl-Prolyl Isomerase NIMA-Interacting-1 (Pin1). J.Med.Chem., 65, 2022
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4PZ4
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6JW1
| Universal RVD R* accommodates 5mC via water-mediated interactions | 分子名称: | DNA (5'-D(*AP*GP*AP*GP*AP*CP*GP*CP*GP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*(5CM)P*GP*CP*GP*TP*CP*TP*CP*T)-3'), TAL effector | 著者 | Liu, L, Yi, C. | 登録日 | 2019-04-18 | 公開日 | 2020-04-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.49 Å) | 主引用文献 | Structural Insights into the Specific Recognition of 5-methylcytosine and 5-hydroxymethylcytosine by TAL Effectors. J.Mol.Biol., 432, 2020
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6JVZ
| RVD HA specifically contacts 5mC through van der Waals interactions | 分子名称: | DNA (5'-D(*AP*GP*AP*GP*AP*CP*GP*CP*GP*AP*AP*GP*GP*GP*AP*CP*A)-3'), DNA (5'-D(*TP*GP*TP*CP*CP*CP*TP*TP*(5CM)P*GP*CP*GP*TP*CP*TP*CP*T)-3'), TAL effector | 著者 | Liu, L, Yi, C. | 登録日 | 2019-04-18 | 公開日 | 2020-04-22 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (2.48 Å) | 主引用文献 | Structural Insights into the Specific Recognition of 5-methylcytosine and 5-hydroxymethylcytosine by TAL Effectors. J.Mol.Biol., 432, 2020
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6LAN
| Structure of CCDC50 and LC3B complex | 分子名称: | Coiled-coil domain-containing protein 50,Microtubule-associated proteins 1A/1B light chain 3B | 著者 | Liu, L, Li, J, Hou, P. | 登録日 | 2019-11-12 | 公開日 | 2020-09-30 | 最終更新日 | 2023-11-22 | 実験手法 | X-RAY DIFFRACTION (1.41 Å) | 主引用文献 | A novel selective autophagy receptor, CCDC50, delivers K63 polyubiquitination-activated RIG-I/MDA5 for degradation during viral infection. Cell Res., 31, 2021
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5WTK
| Crystal structure of RNP complex | 分子名称: | CRISPR-associated endoribonuclease C2c2, RNA (58-MER) | 著者 | Liu, L, Wang, Y. | 登録日 | 2016-12-13 | 公開日 | 2017-02-08 | 最終更新日 | 2023-11-08 | 実験手法 | X-RAY DIFFRACTION (2.651 Å) | 主引用文献 | Two Distant Catalytic Sites Are Responsible for C2c2 RNase Activities Cell, 168, 2017
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5WNO
| Crystal structure of C. elegans LET-23 kinase domain complexed with AMP-PNP | 分子名称: | MAGNESIUM ION, PHOSPHOAMINOPHOSPHONIC ACID-ADENYLATE ESTER, Receptor tyrosine-protein kinase let-23 | 著者 | Liu, L, Thaker, T.M, Jura, N. | 登録日 | 2017-08-01 | 公開日 | 2018-01-31 | 最終更新日 | 2023-10-04 | 実験手法 | X-RAY DIFFRACTION (2.386 Å) | 主引用文献 | Regulation of Kinase Activity in the Caenorhabditis elegans EGF Receptor, LET-23. Structure, 26, 2018
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