8Q3S
| |
8Q24
| |
8Q3T
| |
8Q2Z
| |
6SK8
| DeltaC3 C-terminal truncation of HsNMT1 in complex with MyrCoA and GDCFSKPR substrates | Descriptor: | Apoptosis-inducing factor 3, CHLORIDE ION, GLYCEROL, ... | Authors: | Dian, C, Riviere, F.B, Asensio, T, Giglione, C, Meinnel, T. | Deposit date: | 2019-08-14 | Release date: | 2020-03-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (1.87 Å) | Cite: | High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation. Nat Commun, 11, 2020
|
|
6QRM
| HsNMT1 in complex with both MyrCoA and GNCFSKRRAA substrates | Descriptor: | Apoptosis-inducing factor 3, CHLORIDE ION, COENZYME A, ... | Authors: | Dian, C, Riviere, F.B, Asensio, T, Giglione, C, Meinnel, T. | Deposit date: | 2019-02-19 | Release date: | 2020-03-18 | Last modified: | 2024-01-24 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation. Nat Commun, 11, 2020
|
|
6SK3
| C-terminal HsNMT1 deltaC3 truncation in complex with both MyrCoA and GNCFSKPR substrates | Descriptor: | Apoptosis-inducing factor 3, GLYCEROL, Glycylpeptide N-tetradecanoyltransferase 1, ... | Authors: | Dian, C, Riviere, F.B, Asensio, T, Giglione, C, Meinnel, T. | Deposit date: | 2019-08-14 | Release date: | 2020-03-18 | Last modified: | 2024-05-15 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation. Nat Commun, 11, 2020
|
|
5JF4
| Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor AT019 | Descriptor: | (3R)-3-{3-[(1-benzofuran-3-yl)methyl]-1,2,4-oxadiazol-5-yl}-4-cyclopentyl-N-hydroxybutanamide, ACETATE ION, IMIDAZOLE, ... | Authors: | Fieulaine, S, Giglione, C, Meinnel, T. | Deposit date: | 2016-04-19 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
|
|
5JEX
| Crystal structure of type 2 PDF from Streptococcus agalactiae, crystallized in imidazole buffer | Descriptor: | IMIDAZOLE, Peptide deformylase, ZINC ION | Authors: | Fieulaine, S, Giglione, C, Meinnel, T. | Deposit date: | 2016-04-19 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
|
|
5JF3
| Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor AT018 | Descriptor: | ACETATE ION, IMIDAZOLE, Peptide deformylase, ... | Authors: | Fieulaine, S, Giglione, C, Meinnel, T. | Deposit date: | 2016-04-19 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
|
|
5JF8
| Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor RAS358 (21) | Descriptor: | ACETATE ION, IMIDAZOLE, Peptide deformylase, ... | Authors: | Fieulaine, S, Giglione, C, Meinnel, T. | Deposit date: | 2016-04-19 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
|
|
5JEY
| |
5JF6
| Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor 6b (AB47) | Descriptor: | 2-(5-bromo-1H-indol-3-yl)-N-hydroxyacetamide, ACETATE ION, Peptide deformylase, ... | Authors: | Fieulaine, S, Giglione, C, Meinnel, T, Hamiche, K. | Deposit date: | 2016-04-19 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
|
|
5JF5
| Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor AT020 | Descriptor: | (3R)-3-{3-[(2H-1,3-benzodioxol-5-yl)methyl]-1,2,4-oxadiazol-5-yl}-4-cyclopentyl-N-hydroxybutanamide, ACETATE ION, IMIDAZOLE, ... | Authors: | Fieulaine, S, Giglione, C, Meinnel, T. | Deposit date: | 2016-04-19 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
|
|
5JF0
| Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with tripeptide Met-Ala-Arg | Descriptor: | ACETATE ION, MET-ALA-ARG, NICKEL (II) ION, ... | Authors: | Fieulaine, S, Giglione, C, Meinnel, T. | Deposit date: | 2016-04-19 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
|
|
5JF2
| Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor AT002 | Descriptor: | (3R)-3-{3-[(4-fluorophenyl)methyl]-1,2,4-oxadiazol-5-yl}-N-hydroxyheptanamide, ACETATE ION, IMIDAZOLE, ... | Authors: | Fieulaine, S, Giglione, C, Meinnel, T, Hamiche, K. | Deposit date: | 2016-04-19 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
|
|
5JF1
| Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with actinonin | Descriptor: | ACETATE ION, ACTINONIN, Peptide deformylase, ... | Authors: | Fieulaine, S, Giglione, C, Meinnel, T. | Deposit date: | 2016-04-19 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
|
|
6SKJ
| DeltaC2 C-terminal truncation of HsNMT1 in complex with MyrCoA and GNCFSKPR substrates | Descriptor: | Apoptosis-inducing factor 3, COENZYME A, GLYCEROL, ... | Authors: | Dian, C, Riviere, F.B, Asensio, T, Giglione, C, Meinnel, T. | Deposit date: | 2019-08-15 | Release date: | 2020-03-18 | Last modified: | 2024-10-16 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | High-resolution snapshots of human N-myristoyltransferase in action illuminate a mechanism promoting N-terminal Lys and Gly myristoylation. Nat Commun, 11, 2020
|
|
5JEZ
| Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with tripeptide Met-Ala-Ser | Descriptor: | ACETATE ION, Met-Ala-Ser, Peptide deformylase, ... | Authors: | Fieulaine, S, Giglione, C, Meinnel, T. | Deposit date: | 2016-04-19 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
|
|
5JF7
| Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor SMP289 | Descriptor: | 2-(3-benzyl-5-bromo-1H-indol-1-yl)-N-hydroxyacetamide, ACETATE ION, IMIDAZOLE, ... | Authors: | Fieulaine, S, Giglione, C, Meinnel, T, Hamiche, K. | Deposit date: | 2016-04-19 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
|
|
5C4L
| Conformational alternate of sisomicin in complex with APH(2")-IVa | Descriptor: | (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, (2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-ol, APH(2'')-Id | Authors: | Kaplan, E, Guichou, J.F, Berrou, K, Chaloin, L, Leban, N, Lallemand, P, Barman, T, Serpersu, E.H, Lionne, C. | Deposit date: | 2015-06-18 | Release date: | 2016-02-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Aminoglycoside binding and catalysis specificity of aminoglycoside 2-phosphotransferase IVa: A thermodynamic, structural and kinetic study. Biochim.Biophys.Acta, 1860, 2016
|
|
1ZY1
| X-ray structure of peptide deformylase from Arabidopsis thaliana (AtPDF1A) in complex with Met-Ala-Ser | Descriptor: | Peptide deformylase, mitochondrial, ZINC ION, ... | Authors: | Fieulaine, S, Juillan-Binard, C, Serero, A, Dardel, F, Giglione, C, Meinnel, T, Ferrer, J.-L. | Deposit date: | 2005-06-09 | Release date: | 2005-09-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (3 Å) | Cite: | The crystal structure of mitochondrial (Type 1A) peptide deformylase provides clear guidelines for the design of inhibitors specific for the bacterial forms J.Biol.Chem., 280, 2005
|
|
5MTD
| Crystal structure of PDF from the Vibrio parahaemolyticus bacteriophage VP16T - crystal form II | Descriptor: | NICKEL (II) ION, Putative uncharacterized protein orf60T, TRIETHYLENE GLYCOL, ... | Authors: | Fieulaine, S, Grzela, R, Giglione, C, Meinnel, T. | Deposit date: | 2017-01-09 | Release date: | 2017-09-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The C-terminal residue of phage Vp16 PDF, the smallest peptide deformylase, acts as an offset element locking the active conformation. Sci Rep, 7, 2017
|
|
5MTC
| Crystal structure of PDF from the Vibrio parahaemolyticus bacteriophage VP16T - crystal form I | Descriptor: | NICKEL (II) ION, Putative uncharacterized protein orf60T, ZINC ION | Authors: | Fieulaine, S, Grzela, R, Giglione, C, Meinnel, T. | Deposit date: | 2017-01-09 | Release date: | 2017-09-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The C-terminal residue of phage Vp16 PDF, the smallest peptide deformylase, acts as an offset element locking the active conformation. Sci Rep, 7, 2017
|
|
1ZXZ
| X-ray structure of peptide deformylase from Arabidopsis thaliana (AtPDF1A); crystals grown in PEG-5000 MME as precipitant | Descriptor: | Peptide deformylase, mitochondrial, ZINC ION | Authors: | Fieulaine, S, Juillan-Binard, C, Serero, A, Dardel, F, Giglione, C, Meinnel, T, Ferrer, J.-L. | Deposit date: | 2005-06-09 | Release date: | 2005-09-27 | Last modified: | 2023-08-23 | Method: | X-RAY DIFFRACTION (2.8 Å) | Cite: | The crystal structure of mitochondrial (Type 1A) peptide deformylase provides clear guidelines for the design of inhibitors specific for the bacterial forms J.Biol.Chem., 280, 2005
|
|