1MBI
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1mbi by Molmil](/molmil-images/mine/1mbi) | X-RAY CRYSTAL STRUCTURE OF THE FERRIC SPERM WHALE MYOGLOBIN: IMIDAZOLE COMPLEX AT 2.0 ANGSTROMS RESOLUTION | Descriptor: | IMIDAZOLE, MYOGLOBIN, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Lionetti, C, Guanziroli, M.G, Frigerio, F, Ascenzi, P, Bolognesi, M. | Deposit date: | 1990-06-25 | Release date: | 1991-10-15 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | X-ray crystal structure of the ferric sperm whale myoglobin: imidazole complex at 2.0 A resolution. J.Mol.Biol., 217, 1991
|
|
4IKF
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4ikf by Molmil](/molmil-images/mine/4ikf) | PFV intasome with inhibitor MB-76 | Descriptor: | 5'-D(*AP*TP*TP*GP*TP*CP*AP*TP*GP*GP*AP*AP*TP*TP*TP*CP*GP*CP*A)-3', 5'-D(*TP*GP*CP*GP*AP*AP*AP*TP*TP*CP*CP*AP*TP*GP*AP*CP*A)-3', AMMONIUM ION, ... | Authors: | Taltynov, O, Demeulemeester, J, Desimmie, B.A, Suchaud, V, Billamboz, M, Lion, C, Bailly, F, Debyser, Z, Cotelle, P, Christ, F, Strelkov, S.V. | Deposit date: | 2012-12-26 | Release date: | 2013-04-03 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (3.4 Å) | Cite: | 2-Hydroxyisoquinoline-1,3(2H,4H)-diones (HIDs), novel inhibitors of HIV integrase with a high barrier to resistance. Acs Chem.Biol., 8, 2013
|
|
5JF1
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jf1 by Molmil](/molmil-images/mine/5jf1) | Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with actinonin | Descriptor: | ACETATE ION, ACTINONIN, Peptide deformylase, ... | Authors: | Fieulaine, S, Giglione, C, Meinnel, T. | Deposit date: | 2016-04-19 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
|
|
5JEY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jey by Molmil](/molmil-images/mine/5jey) | |
5JEX
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jex by Molmil](/molmil-images/mine/5jex) | Crystal structure of type 2 PDF from Streptococcus agalactiae, crystallized in imidazole buffer | Descriptor: | IMIDAZOLE, Peptide deformylase, ZINC ION | Authors: | Fieulaine, S, Giglione, C, Meinnel, T. | Deposit date: | 2016-04-19 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
|
|
5JF6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jf6 by Molmil](/molmil-images/mine/5jf6) | Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor 6b (AB47) | Descriptor: | 2-(5-bromo-1H-indol-3-yl)-N-hydroxyacetamide, ACETATE ION, Peptide deformylase, ... | Authors: | Fieulaine, S, Giglione, C, Meinnel, T, Hamiche, K. | Deposit date: | 2016-04-19 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
|
|
5JF3
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jf3 by Molmil](/molmil-images/mine/5jf3) | Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor AT018 | Descriptor: | ACETATE ION, IMIDAZOLE, Peptide deformylase, ... | Authors: | Fieulaine, S, Giglione, C, Meinnel, T. | Deposit date: | 2016-04-19 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
|
|
5JEZ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jez by Molmil](/molmil-images/mine/5jez) | Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with tripeptide Met-Ala-Ser | Descriptor: | ACETATE ION, Met-Ala-Ser, Peptide deformylase, ... | Authors: | Fieulaine, S, Giglione, C, Meinnel, T. | Deposit date: | 2016-04-19 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
|
|
5JF7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jf7 by Molmil](/molmil-images/mine/5jf7) | Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor SMP289 | Descriptor: | 2-(3-benzyl-5-bromo-1H-indol-1-yl)-N-hydroxyacetamide, ACETATE ION, IMIDAZOLE, ... | Authors: | Fieulaine, S, Giglione, C, Meinnel, T, Hamiche, K. | Deposit date: | 2016-04-19 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
|
|
5JF8
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jf8 by Molmil](/molmil-images/mine/5jf8) | Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor RAS358 (21) | Descriptor: | ACETATE ION, IMIDAZOLE, Peptide deformylase, ... | Authors: | Fieulaine, S, Giglione, C, Meinnel, T. | Deposit date: | 2016-04-19 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
|
|
1ACB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1acb by Molmil](/molmil-images/mine/1acb) | CRYSTAL AND MOLECULAR STRUCTURE OF THE BOVINE ALPHA-CHYMOTRYPSIN-EGLIN C COMPLEX AT 2.0 ANGSTROMS RESOLUTION | Descriptor: | ALPHA-CHYMOTRYPSIN, Eglin C | Authors: | Bolognesi, M, Frigerio, F, Coda, A, Pugliese, L, Lionetti, C, Menegatti, E, Amiconi, G, Schnebli, H.P, Ascenzi, P. | Deposit date: | 1991-11-08 | Release date: | 1993-10-31 | Last modified: | 2017-11-29 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Crystal and molecular structure of the bovine alpha-chymotrypsin-eglin c complex at 2.0 A resolution. J.Mol.Biol., 225, 1992
|
|
5MTD
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mtd by Molmil](/molmil-images/mine/5mtd) | Crystal structure of PDF from the Vibrio parahaemolyticus bacteriophage VP16T - crystal form II | Descriptor: | NICKEL (II) ION, Putative uncharacterized protein orf60T, TRIETHYLENE GLYCOL, ... | Authors: | Fieulaine, S, Grzela, R, Giglione, C, Meinnel, T. | Deposit date: | 2017-01-09 | Release date: | 2017-09-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.5 Å) | Cite: | The C-terminal residue of phage Vp16 PDF, the smallest peptide deformylase, acts as an offset element locking the active conformation. Sci Rep, 7, 2017
|
|
5O9S
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5o9s by Molmil](/molmil-images/mine/5o9s) | HsNMT1 in complex with CoA and Myristoylated-GKSNSKLK octapeptide | Descriptor: | CHLORIDE ION, GLYCEROL, Glycylpeptide N-tetradecanoyltransferase 1, ... | Authors: | Dian, C, Meinnel, T, Giglione, C. | Deposit date: | 2017-06-20 | Release date: | 2018-06-27 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Structural and genomic decoding of human and plant myristoylomes reveals a definitive recognition pattern. Nat. Chem. Biol., 14, 2018
|
|
5O9T
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5o9t by Molmil](/molmil-images/mine/5o9t) | HsNMT1 in complex with CoA and acetylated-NCFSKPK peptide | Descriptor: | 1IP-CYS-PHE-SER-LYS-PRO-ARG, CHLORIDE ION, GLYCEROL, ... | Authors: | Dian, C, Meinnel, T, Giglione, C. | Deposit date: | 2017-06-20 | Release date: | 2018-06-27 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.15 Å) | Cite: | Structural and genomic decoding of human and plant myristoylomes reveals a definitive recognition pattern. Nat. Chem. Biol., 14, 2018
|
|
5O9V
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5o9v by Molmil](/molmil-images/mine/5o9v) | HsNMT1 in complex with CoA and Myristoylated-GGCFSKPK octapeptide | Descriptor: | Apoptosis-inducing factor 3, CHLORIDE ION, COENZYME A, ... | Authors: | Dian, C, Meinnel, T, Giglione, C. | Deposit date: | 2017-06-20 | Release date: | 2018-06-27 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (2.201 Å) | Cite: | Structural and genomic decoding of human and plant myristoylomes reveals a definitive recognition pattern. Nat. Chem. Biol., 14, 2018
|
|
5MTC
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mtc by Molmil](/molmil-images/mine/5mtc) | Crystal structure of PDF from the Vibrio parahaemolyticus bacteriophage VP16T - crystal form I | Descriptor: | NICKEL (II) ION, Putative uncharacterized protein orf60T, ZINC ION | Authors: | Fieulaine, S, Grzela, R, Giglione, C, Meinnel, T. | Deposit date: | 2017-01-09 | Release date: | 2017-09-20 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.7 Å) | Cite: | The C-terminal residue of phage Vp16 PDF, the smallest peptide deformylase, acts as an offset element locking the active conformation. Sci Rep, 7, 2017
|
|
5C4L
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5c4l by Molmil](/molmil-images/mine/5c4l) | Conformational alternate of sisomicin in complex with APH(2")-IVa | Descriptor: | (1S,2S,3R,4S,6R)-4,6-diamino-3-{[(2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-yl]oxy}-2-hydroxycyclohexyl 3-deoxy-4-C-methyl-3-(methylamino)-beta-L-arabinopyranoside, (2S,3R)-3-amino-6-(aminomethyl)-3,4-dihydro-2H-pyran-2-ol, APH(2'')-Id | Authors: | Kaplan, E, Guichou, J.F, Berrou, K, Chaloin, L, Leban, N, Lallemand, P, Barman, T, Serpersu, E.H, Lionne, C. | Deposit date: | 2015-06-18 | Release date: | 2016-02-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.35 Å) | Cite: | Aminoglycoside binding and catalysis specificity of aminoglycoside 2-phosphotransferase IVa: A thermodynamic, structural and kinetic study. Biochim.Biophys.Acta, 1860, 2016
|
|
5O9U
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5o9u by Molmil](/molmil-images/mine/5o9u) | HsNMT1 in complex with CoA and Myristoylated-GCSVSKKK octapeptide | Descriptor: | COENZYME A, Calcineurin B-like protein 4, GLYCEROL, ... | Authors: | Dian, C, Meinnel, T, Giglione, C. | Deposit date: | 2017-06-20 | Release date: | 2018-06-27 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural and genomic decoding of human and plant myristoylomes reveals a definitive recognition pattern. Nat. Chem. Biol., 14, 2018
|
|
5C4K
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5c4k by Molmil](/molmil-images/mine/5c4k) | APH(2")-IVa in complex with GET (G418) at room temperature | Descriptor: | APH(2'')-Id, GENETICIN | Authors: | Kaplan, E, Guichou, J.F, Berrou, K, Chaloin, L, Leban, N, Lallemand, P, Barman, T, Serpersu, E.H, Lionne, C. | Deposit date: | 2015-06-18 | Release date: | 2016-02-03 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (3.05 Å) | Cite: | Aminoglycoside binding and catalysis specificity of aminoglycoside 2-phosphotransferase IVa: A thermodynamic, structural and kinetic study. Biochim.Biophys.Acta, 1860, 2016
|
|
7OWR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7owr by Molmil](/molmil-images/mine/7owr) | HsNMT1 in complex with both MyrCoA and peptide GGKSFSKPR | Descriptor: | GLY-GLY-LYS-SER-PHE-SER-LYS-PRO-ARG, GLYCEROL, Glycylpeptide N-tetradecanoyltransferase 1, ... | Authors: | Dian, C, Giglione, C, Meinnel, T. | Deposit date: | 2021-06-18 | Release date: | 2022-12-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.39 Å) | Cite: | Structural and Large-scale Analysis Unveil the Intertwined Paths Promoting NMT-catalyzed Lysine and Glycine Myristoylation. J.Mol.Biol., 434, 2022
|
|
7OWQ
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7owq by Molmil](/molmil-images/mine/7owq) | |
7OWU
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 7owu by Molmil](/molmil-images/mine/7owu) | HsNMT1 in complex with both CoA and Myr-ANCFSKPR peptide | Descriptor: | ALA-ASN-CYS-PHE-SER-LYS-PRO-ARG, COENZYME A, GLYCEROL, ... | Authors: | Dian, C, Giglione, C, Meinnel, T. | Deposit date: | 2021-06-18 | Release date: | 2022-12-21 | Last modified: | 2024-01-31 | Method: | X-RAY DIFFRACTION (2.08 Å) | Cite: | Structural and Large-scale Analysis Unveil the Intertwined Paths Promoting NMT-catalyzed Lysine and Glycine Myristoylation. J.Mol.Biol., 434, 2022
|
|
5JF4
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jf4 by Molmil](/molmil-images/mine/5jf4) | Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor AT019 | Descriptor: | (3R)-3-{3-[(1-benzofuran-3-yl)methyl]-1,2,4-oxadiazol-5-yl}-4-cyclopentyl-N-hydroxybutanamide, ACETATE ION, IMIDAZOLE, ... | Authors: | Fieulaine, S, Giglione, C, Meinnel, T. | Deposit date: | 2016-04-19 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (2.4 Å) | Cite: | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
|
|
5MTE
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5mte by Molmil](/molmil-images/mine/5mte) | Crystal structure of PDF from the Vibrio parahaemolyticus bacteriophage VP16T in complex with actinonin - crystal form II | Descriptor: | ACTINONIN, NICKEL (II) ION, Putative uncharacterized protein orf60T, ... | Authors: | Fieulaine, S, Grzela, R, Giglione, C, Meinnel, T. | Deposit date: | 2017-01-09 | Release date: | 2017-11-29 | Last modified: | 2024-01-17 | Method: | X-RAY DIFFRACTION (1.4 Å) | Cite: | Peptide deformylases from Vibrio parahaemolyticus phage and bacteria display similar deformylase activity and inhibitor binding clefts. Biochim. Biophys. Acta, 1866, 2018
|
|
5JF5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 5jf5 by Molmil](/molmil-images/mine/5jf5) | Crystal structure of type 2 PDF from Streptococcus agalactiae in complex with inhibitor AT020 | Descriptor: | (3R)-3-{3-[(2H-1,3-benzodioxol-5-yl)methyl]-1,2,4-oxadiazol-5-yl}-4-cyclopentyl-N-hydroxybutanamide, ACETATE ION, IMIDAZOLE, ... | Authors: | Fieulaine, S, Giglione, C, Meinnel, T. | Deposit date: | 2016-04-19 | Release date: | 2016-11-30 | Last modified: | 2024-01-10 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | A unique peptide deformylase platform to rationally design and challenge novel active compounds. Sci Rep, 6, 2016
|
|