2B9Z
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![BU of 2b9z by Molmil](/molmil-images/mine/2b9z) | Solution structure of FHV B2, a viral suppressor of RNAi | Descriptor: | B2 protein | Authors: | Lingel, A, Simon, B, Izaurralde, E, Sattler, M. | Deposit date: | 2005-10-13 | Release date: | 2005-11-29 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | The structure of the flock house virus B2 protein, a viral suppressor of RNA interference, shows a novel mode of double-stranded RNA recognition. Embo Rep., 6, 2005
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1T2S
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![BU of 1t2s by Molmil](/molmil-images/mine/1t2s) | Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain | Descriptor: | 5'-D(*CP*TP*CP*AP*C)-3', Argonaute 2 | Authors: | Lingel, A, Simon, B, Izaurralde, E, Sattler, M. | Deposit date: | 2004-04-22 | Release date: | 2004-06-01 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain. Nat.Struct.Mol.Biol., 11, 2004
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1T2R
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![BU of 1t2r by Molmil](/molmil-images/mine/1t2r) | Structural basis for 3' end recognition of nucleic acids by the Drosophila Argonaute 2 PAZ domain | Descriptor: | 5'-R(*CP*UP*CP*AP*C)-3', Argonaute 2 | Authors: | Lingel, A, Simon, B, Izaurralde, E, Sattler, M. | Deposit date: | 2004-04-22 | Release date: | 2004-06-01 | Last modified: | 2024-05-22 | Method: | SOLUTION NMR | Cite: | Nucleic acid 3'-end recognition by the Argonaute2 PAZ domain. Nat.Struct.Mol.Biol., 11, 2004
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2KDD
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![BU of 2kdd by Molmil](/molmil-images/mine/2kdd) | |
2KLL
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![BU of 2kll by Molmil](/molmil-images/mine/2kll) | Solution structure of human interleukin-33 | Descriptor: | Interleukin-33 | Authors: | Lingel, A, Fairbrother, W. | Deposit date: | 2009-07-06 | Release date: | 2009-11-17 | Last modified: | 2024-05-08 | Method: | SOLUTION NMR | Cite: | Structure of IL-33 and its interaction with the ST2 and IL-1RAcP receptors--insight into heterotrimeric IL-1 signaling complexes. Structure, 17, 2009
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1VYN
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![BU of 1vyn by Molmil](/molmil-images/mine/1vyn) | |
2VXG
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![BU of 2vxg by Molmil](/molmil-images/mine/2vxg) | Crystal structure of the conserved C-terminal region of Ge-1 | Descriptor: | CG6181-PA, ISOFORM A | Authors: | Jinek, M, Eulalio, A, Lingel, A, Helms, S, Conti, E, Izaurralde, E. | Deposit date: | 2008-07-04 | Release date: | 2008-09-09 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.9 Å) | Cite: | The C-Terminal Region of Ge-1 Presents Conserved Structural Features Required for P-Body Localization. RNA, 14, 2008
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3T6P
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![BU of 3t6p by Molmil](/molmil-images/mine/3t6p) | IAP antagonist-induced conformational change in cIAP1 promotes E3 ligase activation via dimerization | Descriptor: | Baculoviral IAP repeat-containing protein 2, ZINC ION | Authors: | Dueber, E.C, Schoeffler, A.J, Lingel, A, Elliott, M, Fedorova, A.V, Giannetti, A.M, Zobel, K, Maurer, B, Varfolomeev, E, Wu, P, Wallweber, H, Hymowitz, S, Deshayes, K, Vucic, D, Fairbrother, W.J. | Deposit date: | 2011-07-28 | Release date: | 2011-11-02 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.897 Å) | Cite: | Antagonists induce a conformational change in cIAP1 that promotes autoubiquitination. Science, 334, 2011
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2KJX
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![BU of 2kjx by Molmil](/molmil-images/mine/2kjx) | Solution structure of the extracellular domain of JTB | Descriptor: | Jumping translocation breakpoint protein | Authors: | Rousseau, F, Lingel, A, Pan, B, Fairbrother, W.J, Bazan, F. | Deposit date: | 2009-06-10 | Release date: | 2010-08-11 | Last modified: | 2012-04-18 | Method: | SOLUTION NMR | Cite: | The structure of the extracellular domain of the jumping translocation breakpoint protein reveals a variation of the midkine fold. J.Mol.Biol., 415, 2012
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6B7C
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![BU of 6b7c by Molmil](/molmil-images/mine/6b7c) | Crystal structure of E.coli Phosphopantetheine Adenylyltransferase (PPAT/CoaD) in complex with N-((1,3-dimethyl-1H-pyrazol-5-yl)methyl)-5-methyl-1H-imidazo[4,5-b]pyridin-2-amine | Descriptor: | DI(HYDROXYETHYL)ETHER, DIMETHYL SULFOXIDE, N-[(1,3-dimethyl-1H-pyrazol-5-yl)methyl]-5-methyl-3H-imidazo[4,5-b]pyridin-2-amine, ... | Authors: | Proudfoot, A.W, Bussiere, D, Lingel, A. | Deposit date: | 2017-10-03 | Release date: | 2017-12-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.564 Å) | Cite: | High-Confidence Protein-Ligand Complex Modeling by NMR-Guided Docking Enables Early Hit Optimization. J. Am. Chem. Soc., 139, 2017
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6B7D
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![BU of 6b7d by Molmil](/molmil-images/mine/6b7d) | Crystal structure of E.coli Phosphopantetheine Adenylyltransferase (PPAT/CoaD) in complex with 3-(4-chlorophenyl)-6-methoxy-4,5-dimethylpyridazine | Descriptor: | 3-(4-chlorophenyl)-6-methoxy-4,5-dimethylpyridazine, DIMETHYL SULFOXIDE, POTASSIUM ION, ... | Authors: | Proudfoot, A.W, Bussiere, D, Lingel, A. | Deposit date: | 2017-10-03 | Release date: | 2017-12-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | High-Confidence Protein-Ligand Complex Modeling by NMR-Guided Docking Enables Early Hit Optimization. J. Am. Chem. Soc., 139, 2017
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6B7A
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![BU of 6b7a by Molmil](/molmil-images/mine/6b7a) | Crystal structure of E.coli Phosphopantetheine Adenylyltransferase (PPAT/CoaD) in complex with 2-methyl-1H-benzo[d]imidazol-4-ol | Descriptor: | 2-methyl-1H-benzimidazol-7-ol, CHLORIDE ION, DI(HYDROXYETHYL)ETHER, ... | Authors: | Proudfoot, A.W, Bussiere, D, Lingel, A. | Deposit date: | 2017-10-03 | Release date: | 2017-12-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.991 Å) | Cite: | High-Confidence Protein-Ligand Complex Modeling by NMR-Guided Docking Enables Early Hit Optimization. J. Am. Chem. Soc., 139, 2017
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6B7E
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![BU of 6b7e by Molmil](/molmil-images/mine/6b7e) | Crystal structure of E.coli Phosphopantetheine Adenylyltransferase (PPAT/CoaD) in complex with (R)-4-(5-(difluoromethyl)-1H-imidazol-1-yl)-3,3-dimethylisochroman-1-one | Descriptor: | (4R)-4-[5-(difluoromethyl)-1H-imidazol-1-yl]-3,3-dimethyl-3,4-dihydro-1H-2-benzopyran-1-one, DIMETHYL SULFOXIDE, Phosphopantetheine adenylyltransferase, ... | Authors: | Proudfoot, A.W, Bussiere, D, Lingel, A. | Deposit date: | 2017-10-03 | Release date: | 2017-12-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.104 Å) | Cite: | High-Confidence Protein-Ligand Complex Modeling by NMR-Guided Docking Enables Early Hit Optimization. J. Am. Chem. Soc., 139, 2017
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6B7F
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![BU of 6b7f by Molmil](/molmil-images/mine/6b7f) | Crystal structure of E.coli Phosphopantetheine Adenylyltransferase (PPAT/CoaD) in complex with (R)-3,3-dimethyl-4-(5-vinyl-1H-imidazol-1-yl)isochroman-1-one | Descriptor: | (4R)-4-(5-ethenyl-1H-imidazol-1-yl)-3,3-dimethyl-3,4-dihydro-1H-2-benzopyran-1-one, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, DIMETHYL SULFOXIDE, ... | Authors: | Proudfoot, A.W, Bussiere, D, Lingel, A. | Deposit date: | 2017-10-03 | Release date: | 2017-12-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (2.562 Å) | Cite: | High-Confidence Protein-Ligand Complex Modeling by NMR-Guided Docking Enables Early Hit Optimization. J. Am. Chem. Soc., 139, 2017
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6B7B
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![BU of 6b7b by Molmil](/molmil-images/mine/6b7b) | Crystal structure of E.coli Phosphopantetheine Adenylyltransferase (PPAT/CoaD) in complex with 5-methoxy-2-methyl-1H-indole | Descriptor: | 5-methoxy-2-methyl-1H-indole, DIMETHYL SULFOXIDE, PYROPHOSPHATE 2-, ... | Authors: | Proudfoot, A.W, Bussiere, D, Lingel, A. | Deposit date: | 2017-10-03 | Release date: | 2017-12-27 | Last modified: | 2023-10-04 | Method: | X-RAY DIFFRACTION (1.981 Å) | Cite: | High-Confidence Protein-Ligand Complex Modeling by NMR-Guided Docking Enables Early Hit Optimization. J. Am. Chem. Soc., 139, 2017
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