6B7C

Crystal structure of E.coli Phosphopantetheine Adenylyltransferase (PPAT/CoaD) in complex with N-((1,3-dimethyl-1H-pyrazol-5-yl)methyl)-5-methyl-1H-imidazo[4,5-b]pyridin-2-amine

Summary for 6B7C

Entry DOI	10.2210/pdb6b7c/pdb
Descriptor	Phosphopantetheine adenylyltransferase, N-[(1,3-dimethyl-1H-pyrazol-5-yl)methyl]-5-methyl-3H-imidazo[4,5-b]pyridin-2-amine, SULFATE ION, ... (7 entities in total)
Functional Keywords	coad, transferase
Biological source	Escherichia coli (strain K12)
Cellular location	Cytoplasm : P0A6I6
Total number of polymer chains	2
Total formula weight	39606.99
Authors	Proudfoot, A.W.,Bussiere, D.,Lingel, A. (deposition date: 2017-10-03, release date: 2017-12-27, Last modification date: 2023-10-04)
Primary citation	Proudfoot, A.,Bussiere, D.E.,Lingel, A. High-Confidence Protein-Ligand Complex Modeling by NMR-Guided Docking Enables Early Hit Optimization. J. Am. Chem. Soc., 139:17824-17833, 2017 Cited by PubMed: 29190085 DOI: 10.1021/jacs.7b07171 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (1.564 Å)

Structure validation