3INR
 
 | |
5BR7
 | | Structure of UDP-galactopyranose mutase from Corynebacterium diphtheriae in complex with citrate ion | | 分子名称: | 1,2-ETHANEDIOL, CITRATE ANION, FLAVIN-ADENINE DINUCLEOTIDE, ... | | 著者 | Wangkanont, K, Kiessling, L.L, Forest, K.T. | | 登録日 | 2015-05-29 | | 公開日 | 2016-06-01 | | 最終更新日 | 2023-09-27 | | 実験手法 | X-RAY DIFFRACTION (1.95 Å) | | 主引用文献 | Conformational Control of UDP-Galactopyranose Mutase Inhibition.
Biochemistry, 56, 2017
|
|
3F41
 | | Structure of the tandemly repeated protein tyrosine phosphatase like phytase from Mitsuokella multacida | | 分子名称: | 1,2-ETHANEDIOL, PHOSPHATE ION, Phytase | | 著者 | Gruninger, R.J, Selinger, L.B, Mosimann, S.C. | | 登録日 | 2008-10-31 | | 公開日 | 2009-06-09 | | 最終更新日 | 2023-12-27 | | 実験手法 | X-RAY DIFFRACTION (2.3 Å) | | 主引用文献 | Structural analysis of a multifunctional, tandemly repeated inositol polyphosphatase.
J.Mol.Biol., 392, 2009
|
|
7JKQ
 | | Human DPP9-CARD8 complex | | 分子名称: | Caspase recruitment domain-containing protein 8, Dipeptidyl peptidase 9 | | 著者 | Sharif, H, Hollingsworth, L.R. | | 登録日 | 2020-07-28 | | 公開日 | 2021-05-26 | | 最終更新日 | 2024-03-06 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment.
Immunity, 54, 2021
|
|
4POG
 | | MCM-ssDNA co-crystal structure | | 分子名称: | 30-mer oligo(dT), Cell division control protein 21, ZINC ION | | 著者 | Froelich, C.A, Kang, S, Epling, L.B, Bell, S.P, Enemark, E.J. | | 登録日 | 2014-02-25 | | 公開日 | 2014-04-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (3.203 Å) | | 主引用文献 | A conserved MCM single-stranded DNA binding element is essential for replication initiation.
Elife, 3, 2014
|
|
7JN7
 | | Human DPP9-CARD8 complex | | 分子名称: | Caspase recruitment domain-containing protein 8, Dipeptidyl peptidase 9, [(2~{R})-1-[(2~{R})-2-azanyl-3-methyl-butanoyl]pyrrolidin-2-yl]boronic acid | | 著者 | Sharif, H, Hollingsworth, L.R. | | 登録日 | 2020-08-04 | | 公開日 | 2021-05-19 | | 最終更新日 | 2021-07-28 | | 実験手法 | ELECTRON MICROSCOPY (3.3 Å) | | 主引用文献 | Dipeptidyl peptidase 9 sets a threshold for CARD8 inflammasome formation by sequestering its active C-terminal fragment.
Immunity, 54, 2021
|
|
3O3L
 | | Structure of the PTP-like phytase from Selenomonas ruminantium in complex with myo-inositol (1,3,4,5)tetrakisphosphate | | 分子名称: | ACETATE ION, CHLORIDE ION, GLYCEROL, ... | | 著者 | Gruninger, R.J, Selinger, L.B, Mosimann, S.C. | | 登録日 | 2010-07-25 | | 公開日 | 2011-12-07 | | 最終更新日 | 2024-02-21 | | 実験手法 | X-RAY DIFFRACTION (1.85 Å) | | 主引用文献 | Structural analysis of substrate binding in PTPLPs
To be Published
|
|
3D1Q
 | | Structure of the PTP-Like Phytase Expressed by Selenomonas Ruminantium at an Ionic Strength of 400 mM | | 分子名称: | CHLORIDE ION, GLYCEROL, Myo-inositol hexaphosphate phosphohydrolase | | 著者 | Gruninger, R.J, Selinger, L.B, Mosimann, S.C. | | 登録日 | 2008-05-06 | | 公開日 | 2008-06-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Effect of ionic strength and oxidation on the P-loop conformation of the protein tyrosine phosphatase-like phytase, PhyAsr.
Febs J., 275, 2008
|
|
3D1H
 | |
3D1O
 | | Structure of the PTP-Like Phytase Expressed by Selenomonas Ruminantium at an Ionic Strength of 300 mM | | 分子名称: | CHLORIDE ION, GLYCEROL, Myo-inositol hexaphosphate phosphohydrolase | | 著者 | Gruninger, R.J, Selinger, L.B, Mosimann, S.C. | | 登録日 | 2008-05-06 | | 公開日 | 2008-06-24 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (2.1 Å) | | 主引用文献 | Effect of ionic strength and oxidation on the P-loop conformation of the protein tyrosine phosphatase-like phytase, PhyAsr.
Febs J., 275, 2008
|
|
4POF
 | | PfMCM N-terminal domain without DNA | | 分子名称: | Cell division control protein 21, ZINC ION | | 著者 | Froelich, C.A, Kang, S, Epling, L.B, Bell, S.P, Enemark, E.J. | | 登録日 | 2014-02-25 | | 公開日 | 2014-04-09 | | 最終更新日 | 2023-09-20 | | 実験手法 | X-RAY DIFFRACTION (2.648 Å) | | 主引用文献 | A conserved MCM single-stranded DNA binding element is essential for replication initiation.
Elife, 3, 2014
|
|
4MAD
 | | Crystal structure of beta-galactosidase C (BgaC) from Bacillus circulans ATCC 31382 | | 分子名称: | 2-(2-METHOXYETHOXY)ETHANOL, Beta-galactosidase | | 著者 | Kamerke, C, You, D.J, Kanaya, S, Elling, L. | | 登録日 | 2013-08-16 | | 公開日 | 2014-08-27 | | 最終更新日 | 2023-11-08 | | 実験手法 | X-RAY DIFFRACTION (1.8 Å) | | 主引用文献 | Rational design of a glycosynthase by the crystal structure of beta-galactosidase from Bacillus circulans (BgaC) and its use for the synthesis of N-acetyllactosamine type 1 glycan structures.
J.Biotechnol., 191, 2014
|
|
6YVR
 | | Crystal structure of the neurotensin receptor 1 in complex with the peptide full agonist NTS8-13 | | 分子名称: | Neurotensin receptor type 1,Neurotensin receptor type 1,DARPin crystallisation chaperone, neurotensin NTS8-13 (full agonist), nonyl beta-D-glucopyranoside | | 著者 | Deluigi, M, Merklinger, L, Hilge, M, Ernst, P, Klipp, A, Klenk, C, Plueckthun, A. | | 登録日 | 2020-04-28 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.458 Å) | | 主引用文献 | Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism.
Sci Adv, 7, 2021
|
|
2QMT
 | | Crystal Polymorphism of Protein GB1 Examined by Solid-state NMR and X-ray Diffraction | | 分子名称: | (4R)-2-METHYLPENTANE-2,4-DIOL, ISOPROPYL ALCOHOL, Immunoglobulin G-binding protein G, ... | | 著者 | Frericks Schmidt, H.L, Sperling, L.J, Gao, Y.G, Wylie, B.J, Boettcher, J.M, Wilson, S.R, Rienstra, C.M. | | 登録日 | 2007-07-16 | | 公開日 | 2007-12-25 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.05 Å) | | 主引用文献 | Crystal Polymorphism of Protein GB1 Examined by Solid-State NMR Spectroscopy and X-ray Diffraction.
J.Phys.Chem.B, 111, 2007
|
|
6Z4Q
 | | Crystal structure of the neurotensin receptor 1 in complex with the small-molecule inverse agonist SR142948A | | 分子名称: | 2-[[5-(2,6-dimethoxyphenyl)-1-[4-[3-(dimethylamino)propyl-methyl-carbamoyl]-2-propan-2-yl-phenyl]pyrazol-3-yl]carbonylamino]adamantane-2-carboxylic acid, Neurotensin receptor type 1,Neurotensin receptor type 1,DARPin | | 著者 | Deluigi, M, Klipp, A, Hilge, M, Merklinger, L, Klenk, C, Plueckthun, A. | | 登録日 | 2020-05-25 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.923 Å) | | 主引用文献 | Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism.
Sci Adv, 7, 2021
|
|
6ZIN
 | | Crystal structure of the neurotensin receptor 1 in complex with the small molecule inverse agonist SR48692 | | 分子名称: | 2-[[1-(7-chloranylquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazol-3-yl]carbonylamino]adamantane-2-carboxylic acid, Neurotensin receptor type 1,DARPin,HRV 3C protease recognition sequence | | 著者 | Deluigi, M, Klipp, A, Hilge, M, Merklinger, L, Klenk, C, Plueckthun, A. | | 登録日 | 2020-06-26 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-01-31 | | 実験手法 | X-RAY DIFFRACTION (2.639 Å) | | 主引用文献 | Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism.
Sci Adv, 7, 2021
|
|
6Z8N
 | | Crystal structure of the neurotensin receptor 1 in complex with the small-molecule full agonist SRI-9829 | | 分子名称: | (2~{S})-4-methyl-2-[(1-quinolin-8-ylsulfonylindol-3-yl)carbonylamino]pentanoic acid, Neurotensin receptor type 1,Neurotensin receptor type 1,Neurotensin receptor type 1,Neurotensin receptor type 1,Neurotensin receptor 1 (NTSR1),Neurotensin receptor 1 (NTSR1) | | 著者 | Deluigi, M, Klipp, A, Hilge, M, Merklinger, L, Klenk, C, Plueckthun, A. | | 登録日 | 2020-06-02 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.803 Å) | | 主引用文献 | Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism.
Sci Adv, 7, 2021
|
|
6Z4S
 | | Crystal structure of the neurotensin receptor 1 (NTSR1-H4bmx) in complex with the small molecule inverse agonist SR48692 | | 分子名称: | 2-[[1-(7-chloranylquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazol-3-yl]carbonylamino]adamantane-2-carboxylic acid, Neurotensin receptor type 1,DARPin,HRV 3C protease recognition sequence | | 著者 | Deluigi, M, Klipp, A, Hilge, M, Merklinger, L, Klenk, C, Plueckthun, A. | | 登録日 | 2020-05-25 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.707 Å) | | 主引用文献 | Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism.
Sci Adv, 7, 2021
|
|
6Z66
 | | Crystal structure of apo-state neurotensin receptor 1 | | 分子名称: | Neurotensin receptor type 1,Neurotensin receptor type 1,DARPin | | 著者 | Deluigi, M, Klipp, A, Hilge, M, Merklinger, L, Klenk, C, Plueckthun, A. | | 登録日 | 2020-05-27 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (3.192 Å) | | 主引用文献 | Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism.
Sci Adv, 7, 2021
|
|
6ZA8
 | | Crystal structure of the neurotensin receptor 1 in complex with the small-molecule partial agonist RTI-3a | | 分子名称: | (2~{S})-2-[[1-(7-chloranylquinolin-4-yl)-5-(2,6-dimethoxyphenyl)pyrazol-3-yl]carbonylamino]-4-methyl-pentanoic acid, Neurotensin receptor type 1,Neurotensin receptor type 1,Neurotensin receptor 1 (NTSR1),Neurotensin receptor 1 (NTSR1),Neurotensin receptor type 1,Neurotensin receptor 1 (NTSR1),Neurotensin receptor 1 (NTSR1) | | 著者 | Deluigi, M, Klipp, A, Hilge, M, Merklinger, L, Klenk, C, Plueckthun, A. | | 登録日 | 2020-06-05 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.72 Å) | | 主引用文献 | Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism.
Sci Adv, 7, 2021
|
|
6Z4V
 | | Crystal structure of the neurotensin receptor 1 (NTSR1-H4bmx) in complex with NTS8-13 | | 分子名称: | ARG-PRO-TYR-ILE-LEU, Neurotensin receptor type 1,Neurotensin receptor type 1,DARPin | | 著者 | Deluigi, M, Klipp, A, Hilge, M, Merklinger, L, Klenk, C, Plueckthun, A. | | 登録日 | 2020-05-25 | | 公開日 | 2021-02-10 | | 最終更新日 | 2024-01-24 | | 実験手法 | X-RAY DIFFRACTION (2.595 Å) | | 主引用文献 | Complexes of the neurotensin receptor 1 with small-molecule ligands reveal structural determinants of full, partial, and inverse agonism.
Sci Adv, 7, 2021
|
|
2FW0
 | | Apo Open Form of Glucose/Galactose Binding Protein | | 分子名称: | CALCIUM ION, CITRIC ACID, D-galactose-binding periplasmic protein, ... | | 著者 | Borrok, M.J, Kiessling, L.L, Forest, K.T. | | 登録日 | 2006-01-31 | | 公開日 | 2007-02-06 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.55 Å) | | 主引用文献 | Conformational changes of glucose/galactose-binding protein illuminated by open, unliganded, and ultra-high-resolution ligand-bound structures.
Protein Sci., 16, 2007
|
|
2FVY
 | | High Resolution Glucose Bound Crystal Structure of GGBP | | 分子名称: | ACETATE ION, CALCIUM ION, CARBON DIOXIDE, ... | | 著者 | Borrok, M.J, Kiessling, L.L, Forest, K.T. | | 登録日 | 2006-01-31 | | 公開日 | 2007-02-06 | | 最終更新日 | 2024-04-03 | | 実験手法 | X-RAY DIFFRACTION (0.92 Å) | | 主引用文献 | Conformational changes of glucose/galactose-binding protein illuminated by open, unliganded, and ultra-high-resolution ligand-bound structures.
Protein Sci., 16, 2007
|
|
4QCJ
 | | Crystal Structure of OdhI from Corynebacterium glutamicum | | 分子名称: | Oxoglutarate dehydrogenase inhibitor | | 著者 | Labahn, J, Raasch, K, Eggeling, L, Bocola, M, Leitner, A, Bott, M. | | 登録日 | 2014-05-12 | | 公開日 | 2014-07-02 | | 最終更新日 | 2024-02-28 | | 実験手法 | X-RAY DIFFRACTION (2 Å) | | 主引用文献 | Interaction of 2-oxoglutarate dehydrogenase OdhA with its inhibitor OdhI in Corynebacterium glutamicum: Mutants and a model.
J.Biotechnol., 191, 2014
|
|
2QW1
 | | Glucose/galactose binding protein bound to 3-O-methyl D-glucose | | 分子名称: | 3-O-methyl-beta-D-glucopyranose, CALCIUM ION, D-galactose-binding periplasmic protein, ... | | 著者 | Borrok, M.J, Kiessling, L.L, Forest, K.T. | | 登録日 | 2007-08-09 | | 公開日 | 2008-08-05 | | 最終更新日 | 2023-08-30 | | 実験手法 | X-RAY DIFFRACTION (1.7 Å) | | 主引用文献 | Structure-based design of a periplasmic binding protein antagonist that prevents domain closure.
Acs Chem.Biol., 4, 2009
|
|
