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PDB: 216 results

5W3N
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BU of 5w3n by Molmil
Molecular structure of FUS low sequence complexity domain protein fibrils
Descriptor: RNA-binding protein FUS
Authors:Murray, D.T, Kato, M, Lin, Y, Thurber, K, Hung, I, McKnight, S, Tycko, R.
Deposit date:2017-06-08
Release date:2017-09-27
Last modified:2024-05-15
Method:SOLID-STATE NMR
Cite:Structure of FUS Protein Fibrils and Its Relevance to Self-Assembly and Phase Separation of Low-Complexity Domains.
Cell, 171, 2017
1BH0
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BU of 1bh0 by Molmil
STRUCTURE OF A GLUCAGON ANALOG
Descriptor: GLUCAGON
Authors:Sturm, N.S, Lin, Y, Burley, S.K, Krstenansky, J.L, Ahn, J.-M, Azizeh, B.Y, Trivedi, D, Hruby, V.J.
Deposit date:1998-06-11
Release date:1998-11-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (3 Å)
Cite:Structure-function studies on positions 17, 18, and 21 replacement analogues of glucagon: the importance of charged residues and salt bridges in glucagon biological activity.
J.Med.Chem., 41, 1998
6QNN
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BU of 6qnn by Molmil
CLATHRIN HEAVY CHAIN N-TERMINAL DOMAIN BOUND TO GTSE1 LIDL MOTIF
Descriptor: Clathrin heavy chain 1, G2 and S phase-expressed protein 1
Authors:Porfetye, A.T, Lin, Y, Vetter, I.R.
Deposit date:2019-02-11
Release date:2019-08-28
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.03 Å)
Cite:Clathrin's adaptor interaction sites are repurposed to stabilize microtubules during mitosis.
J.Cell Biol., 219, 2020
6QNP
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CLATHRIN HEAVY CHAIN N-TERMINAL DOMAIN BOUND TO GTSE1 LIDL MOTIF
Descriptor: Clathrin heavy chain 1, G2 and S phase-expressed protein 1
Authors:Porfetye, A.T, Lin, Y, Vetter, I.R.
Deposit date:2019-02-11
Release date:2019-08-28
Last modified:2024-01-24
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Clathrin's adaptor interaction sites are repurposed to stabilize microtubules during mitosis.
J.Cell Biol., 219, 2020
8IMZ
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BU of 8imz by Molmil
Cryo-EM structure of mouse Piezo1-MDFIC complex (composite map)
Descriptor: MyoD family inhibitor domain-containing protein, Piezo-type mechanosensitive ion channel component 1
Authors:Zhou, Z, Ma, X, Lin, Y, Cheng, D, Bavi, N, Li, J.V, Sutton, D, Yao, M, Harvey, N, Corry, B, Zhang, Y, Cox, C.D.
Deposit date:2023-03-07
Release date:2023-08-09
Last modified:2023-08-30
Method:ELECTRON MICROSCOPY (3.66 Å)
Cite:MyoD-family inhibitor proteins act as auxiliary subunits of Piezo channels.
Science, 381, 2023
3SHB
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BU of 3shb by Molmil
Crystal Structure of PHD Domain of UHRF1
Descriptor: E3 ubiquitin-protein ligase UHRF1, Histone H3 peptide, ZINC ION
Authors:Hu, L, Li, Z, Wang, P, Lin, Y, Xu, Y.
Deposit date:2011-06-16
Release date:2011-08-24
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of PHD domain of UHRF1 and insights into recognition of unmodified histone H3 arginine residue 2.
Cell Res., 2011
4N7R
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BU of 4n7r by Molmil
Crystal structure of Arabidopsis glutamyl-tRNA reductase in complex with its binding protein
Descriptor: Genomic DNA, chromosome 3, P1 clone: MXL8, ...
Authors:Zhao, A, Fang, Y, Lin, Y, Gong, W, Liu, L.
Deposit date:2013-10-16
Release date:2014-05-14
Last modified:2024-03-20
Method:X-RAY DIFFRACTION (2.802 Å)
Cite:Crystal structure of Arabidopsis glutamyl-tRNA reductase in complex with its stimulator protein
Proc.Natl.Acad.Sci.USA, 111, 2014
4MDR
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BU of 4mdr by Molmil
Crystal structure of adaptor protein complex 4 (AP-4) mu4 subunit C-terminal domain D190A mutant, in complex with a sorting peptide from the amyloid precursor protein (APP)
Descriptor: AP-4 complex subunit mu-1, Amyloid beta A4 protein
Authors:Ross, B.H, Lin, Y, Corales, E.A, Burgos, P.V, Mardones, G.A.
Deposit date:2013-08-23
Release date:2014-03-12
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (1.85 Å)
Cite:Structural and Functional Characterization of Cargo-Binding Sites on the mu 4-Subunit of Adaptor Protein Complex 4.
Plos One, 9, 2014
5U6I
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BU of 5u6i by Molmil
Discovery of MLi-2, an Orally Available and Selective LRRK2 Inhibitor that Reduces Brain Kinase Activity
Descriptor: 3-[2-(morpholin-4-yl)pyridin-4-yl]-5-[(propan-2-yl)oxy]-1H-indazole, Mitogen-activated protein kinase 1, SULFATE ION
Authors:Scott, J.D, DeMong, D.E, Fell, M.J, Mirescu, C, Basu, K, Greshock, T.J, Morrow, J.A, Xiao, L, Hruza, A, Harris, J, Tiscia, H.E, Chang, R.K, Embrey, M.W, McCauley, J.A, Li, W, Lin, S, Liu, H, Dai, X, Baptista, M, Agnihotri, G, Columbus, J, Mei, H, Poirier, M, Zhou, X, Lin, Y, Yin, Z, Sanders, J.M, Drolet, R.E, Kern, J.T, Kennedy, M.E, Parker, E.M, Stamford, A.W, Nargund, R, Miller, M.W.
Deposit date:2016-12-08
Release date:2017-03-15
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.69 Å)
Cite:Discovery of a 3-(4-Pyrimidinyl) Indazole (MLi-2), an Orally Available and Selective Leucine-Rich Repeat Kinase 2 (LRRK2) Inhibitor that Reduces Brain Kinase Activity.
J. Med. Chem., 60, 2017
2HGA
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BU of 2hga by Molmil
Solution NMR Structure of Conserved protein MTH1368, Northeast Structural Genomics Consortium Target TT821A
Descriptor: Conserved protein MTH1368
Authors:Liu, G, Lin, Y, Parish, D, Shen, Y, Sukumaran, D, Yee, A, Semesi, A, Arrowsmith, C, Szyperski, T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2006-06-26
Release date:2006-07-25
Last modified:2024-05-29
Method:SOLUTION NMR
Cite:Solution NMR Structure of Conserved protein MTH1368, Northeast Structural Genomics Consortium Target TT821A
TO BE PUBLISHED
4V0J
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BU of 4v0j by Molmil
The channel-block Ser202Glu, Thr104Lys double mutant of Stearoyl-ACP- Desaturase from Castor bean (Ricinus communis)
Descriptor: ACYL-[ACYL-CARRIER-PROTEIN] DESATURASE, CHLOROPLASTIC, FE (II) ION, ...
Authors:Moche, M, Guy, J, Whittle, E, Lindqvist, Y, Shanklin, J.
Deposit date:2014-09-17
Release date:2015-08-26
Last modified:2024-01-10
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Half-of-the-Sites Reactivity of the Castor Delta9-18:0-Acp Desaturase.
Plant Physiol., 169, 2015
7Y62
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BU of 7y62 by Molmil
Crystal structure of human TFEB HLHLZ domain
Descriptor: Transcription factor EB
Authors:Yang, G, Li, P, Lin, Y, Liu, Z, Sun, H, Zhao, Z, Fang, P, Wang, J.
Deposit date:2022-06-18
Release date:2023-03-22
Last modified:2023-11-29
Method:X-RAY DIFFRACTION (2 Å)
Cite:A small-molecule drug inhibits autophagy gene expression through the central regulator TFEB.
Proc.Natl.Acad.Sci.USA, 120, 2023
2GHW
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BU of 2ghw by Molmil
Crystal structure of SARS spike protein receptor binding domain in complex with a neutralizing antibody, 80R
Descriptor: CHLORIDE ION, Spike glycoprotein, anti-sars scFv antibody, ...
Authors:Hwang, W.C, Lin, Y, Santelli, E, Sui, J, Jaroszewski, L, Stec, B, Farzan, M, Marasco, W.A, Liddington, R.C.
Deposit date:2006-03-27
Release date:2006-09-19
Last modified:2023-08-30
Method:X-RAY DIFFRACTION (2.3 Å)
Cite:Structural basis of neutralization by a human anti-severe acute respiratory syndrome spike protein antibody, 80R.
J.Biol.Chem., 281, 2006
2GHV
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BU of 2ghv by Molmil
Crystal structure of SARS spike protein receptor binding domain
Descriptor: Spike glycoprotein
Authors:Hwang, W.C, Lin, Y, Santelli, E, Sui, J, Jaroszewski, L, Stec, B, Farzan, M, Marasco, W.A, Liddington, R.C.
Deposit date:2006-03-27
Release date:2006-09-19
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural basis of neutralization by a human anti-severe acute respiratory syndrome spike protein antibody, 80R.
J.Biol.Chem., 281, 2006
2LKN
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BU of 2lkn by Molmil
Solution structure of the PPIase domain of human aryl-hydrocarbon receptor-interacting protein (AIP)
Descriptor: AH receptor-interacting protein
Authors:Linnert, M, Lin, Y, Manns, A, Haupt, K, Paschke, A, Fischer, G, Weiwad, M, Luecke, C.
Deposit date:2011-10-17
Release date:2012-10-17
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:The FKBP-Type Domain of the Human Aryl Hydrocarbon Receptor-Interacting Protein Reveals an Unusual Hsp90 Interaction.
Biochemistry, 52, 2013
1RHT
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BU of 1rht by Molmil
24-MER RNA HAIRPIN COAT PROTEIN BINDING SITE FOR BACTERIOPHAGE R17 (NMR, MINIMIZED AVERAGE STRUCTURE)
Descriptor: RNA (5'-R(P*GP*GP*GP*AP*CP*UP*GP*AP*CP*GP*AP*UP*CP*AP*CP*GP*CP*AP*GP*UP*CP*UP*AP*U)-3')
Authors:Borer, P.N, Lin, Y, Wang, S, Roggenbuck, M.W, Gott, J.M, Uhlenbeck, O.C, Pelczer, I.
Deposit date:1995-03-03
Release date:1995-06-03
Last modified:2024-05-22
Method:SOLUTION NMR
Cite:Proton NMR and structural features of a 24-nucleotide RNA hairpin.
Biochemistry, 34, 1995
2MOG
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BU of 2mog by Molmil
Solution structure of the terminal Ig-like domain from Leptospira interrogans LigB
Descriptor: Bacterial Ig-like domain, group 2
Authors:Ptak, C.P, Hsieh, C, Lin, Y, Maltsev, A.S, Raman, R, Sharma, Y, Oswald, R.E, Chang, Y.
Deposit date:2014-04-25
Release date:2014-08-13
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:NMR Solution Structure of the Terminal Immunoglobulin-like Domain from the Leptospira Host-Interacting Outer Membrane Protein, LigB.
Biochemistry, 53, 2014
1I7K
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BU of 1i7k by Molmil
CRYSTAL STRUCTURE OF HUMAN MITOTIC-SPECIFIC UBIQUITIN-CONJUGATING ENZYME, UBCH10
Descriptor: UBIQUITIN-CONJUGATING ENZYME E2 H10
Authors:Basavappa, R, Lin, Y.
Deposit date:2001-03-09
Release date:2001-04-04
Last modified:2023-08-09
Method:X-RAY DIFFRACTION (1.95 Å)
Cite:Structural and functional analysis of the human mitotic-specific ubiquitin-conjugating enzyme, UbcH10.
J.Biol.Chem., 277, 2002
2OEY
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BU of 2oey by Molmil
Solution Structure of a Designed Spirocyclic Helical Ligand Binding at a Two-Base Bulge Site in DNA
Descriptor: (1R,3A'S,10'S,10A'R)-7-METHOXY-2-OXO-10',10A'-DIHYDRO-2H,3A'H-SPIRO[NAPHTHALENE-1,3'-PENTALENO[1,2-B]NAPHTHALEN]-10'-YL 2,6-DIDEOXY-2-(METHYLAMINO)-ALPHA-D-GALACTOPYRANOSIDE, DNA (25-MER)
Authors:Zhang, N, Lin, Y, Xiao, Z, Jones, G.B, Goldberg, I.H.
Deposit date:2007-01-01
Release date:2007-04-10
Last modified:2023-12-27
Method:SOLUTION NMR
Cite:Solution Structure of a Designed Spirocyclic Helical Ligand Binding at a Two-Base Bulge Site in DNA.
Biochemistry, 46, 2007
1DAM
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BU of 1dam by Molmil
DETHIOBIOTIN SYNTHETASE COMPLEXED WITH DETHIOBIOTIN, ADP, INORGANIC PHOSPHATE AND MAGNESIUM
Descriptor: 6-(5-METHYL-2-OXO-IMIDAZOLIDIN-4-YL)-HEXANOIC ACID, ADENOSINE-5'-DIPHOSPHATE, MAGNESIUM ION, ...
Authors:Kaeck, H, Sandmark, J, Gibson, K.J, Schneider, G, Lindqvist, Y.
Deposit date:1998-08-31
Release date:1999-01-13
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal structure of two quaternary complexes of dethiobiotin synthetase, enzyme-MgADP-AlF3-diaminopelargonic acid and enzyme-MgADP-dethiobiotin-phosphate; implications for catalysis.
Protein Sci., 7, 1998
2N3Z
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BU of 2n3z by Molmil
Solution NMR Structure of de novo designed protein, Rossmann2x2 Fold, Northeast Structural Genomics Consortium (NESG) Target OR446
Descriptor: OR446
Authors:Liu, G, Lin, Y, Koga, N, Koga, R, Xiao, R, Janjua, H, Pederson, K, Acton, T.B, Kornhaber, G, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2015-06-15
Release date:2015-09-16
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution NMR Structure of DE NOVO DESIGNED PROTEIN, Rossmann2x2 Fold, Northeast Structural Genomics Consortium (NESG) Target OR446
To be Published
2N2T
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BU of 2n2t by Molmil
Solution NMR Structure of DE NOVO DESIGNED PROTEIN (FDA_60), Northeast Structural Genomics Consortium (NESG) Target OR303
Descriptor: OR303
Authors:Liu, G, Lin, Y, Koga, N, Koga, R, Xiao, R, Janjua, H, Hamilton, K, Acton, T.B, Kornhaber, G, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2015-05-14
Release date:2015-09-16
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution NMR Structure of DE NOVO DESIGNED PROTEIN (FDA_60), Northeast Structural Genomics Consortium (NESG) Target OR303
To be Published
2N2U
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BU of 2n2u by Molmil
Solution NMR Structure of DE NOVO DESIGNED Ferredoxin Fold PROTEIN sfr3, Northeast Structural Genomics Consortium (NESG) Target OR358
Descriptor: OR358
Authors:Liu, G, Lin, Y, Koga, N, Koga, R, Xiao, R, Janjua, H, Hamilton, K, Pederson, K, Acton, T.B, Kornhaber, G, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2015-05-14
Release date:2015-09-16
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution NMR Structure of DE NOVO DESIGNED Ferredoxin Fold PROTEIN sfr3, Northeast Structural Genomics Consortium (NESG) Target OR358
To be Published
2N76
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BU of 2n76 by Molmil
Solution NMR Structure of De novo designed protein LFR1 1 with ferredoxin fold, Northeast Structural Genomics Consortium (NESG) Target OR414
Descriptor: De novo designed protein LFR1
Authors:Liu, G, Lin, Y, Koga, N, Koga, R, Xiao, R, Janjua, H, Pederson, K, Acton, T.B, Kornhaber, G, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2015-09-03
Release date:2016-01-27
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution NMR Structure of De novo designed protein LFR1 1 with ferredoxin fold, Northeast Structural Genomics Consortium (NESG) Target OR414
To be Published
2N75
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BU of 2n75 by Molmil
Solution NMR Structure of De novo designed protein, Rossmann2x2 Fold, Northeast Structural Genomics Consortium (NESG) Target OR446
Descriptor: De novo designed protein
Authors:Liu, G, Lin, Y, Koga, N, Koga, R, Xiao, R, Janjua, H, Pederson, K, Acton, T.B, Kornhaber, G, Everett, J.K, Baker, D, Montelione, G.T, Northeast Structural Genomics Consortium (NESG)
Deposit date:2015-09-03
Release date:2016-01-27
Last modified:2024-05-15
Method:SOLUTION NMR
Cite:Solution NMR Structure of De novo designed protein, Rossmann2x2 Fold, Northeast Structural Genomics Consortium (NESG) Target OR446
To be Published

221716

数据于2024-06-26公开中

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