3QYL
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![BU of 3qyl by Molmil](/molmil-images/mine/3qyl) | Sensitivity of receptor internal motions to ligand binding affinity and kinetic off-rate | Descriptor: | (7S)-7-methyl-5,6,7,8-tetrahydroquinazoline-2,4-diamine, CALCIUM ION, CHLORIDE ION, ... | Authors: | Collins, E.J, Lee, A.L, Carroll, M.J, Mauldin, R.V, Gromova, A.V, Singleton, S.F. | Deposit date: | 2011-03-03 | Release date: | 2012-01-18 | Last modified: | 2024-02-21 | Method: | X-RAY DIFFRACTION (1.79 Å) | Cite: | Evidence for dynamics in proteins as a mechanism for ligand dissociation. Nat.Chem.Biol., 8, 2012
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3F7D
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![BU of 3f7d by Molmil](/molmil-images/mine/3f7d) | SF-1 LBD bound by phosphatidylcholine | Descriptor: | (2S)-2-{[(1R)-1-hydroxyhexadecyl]oxy}-3-{[(1R)-1-hydroxyoctadecyl]oxy}propyl 2-(trimethylammonio)ethyl phosphate, Peroxisome proliferator-activated receptor gamma coactivator 1-alpha, nuclear receptor SF-1 | Authors: | Sablin, E.P, Fletterick, R.J. | Deposit date: | 2008-11-07 | Release date: | 2008-12-09 | Last modified: | 2023-09-06 | Method: | X-RAY DIFFRACTION (2.2 Å) | Cite: | Structure of SF-1 bound by different phospholipids: evidence for regulatory ligands. Mol.Endocrinol., 23, 2009
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4EU9
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![BU of 4eu9 by Molmil](/molmil-images/mine/4eu9) | |
4HL6
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![BU of 4hl6 by Molmil](/molmil-images/mine/4hl6) | |
4EUA
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![BU of 4eua by Molmil](/molmil-images/mine/4eua) | |
4EU7
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![BU of 4eu7 by Molmil](/molmil-images/mine/4eu7) | |
4EUB
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![BU of 4eub by Molmil](/molmil-images/mine/4eub) | Succinyl-CoA:acetate CoA-transferase (AarCH6-E294A) in complex with CoA | Descriptor: | CHLORIDE ION, COENZYME A, Succinyl-CoA:acetate coenzyme A transferase | Authors: | Mullins, E.A, Kappock, T.J. | Deposit date: | 2012-04-25 | Release date: | 2012-10-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.973 Å) | Cite: | Crystal Structures of Acetobacter aceti Succinyl-Coenzyme A (CoA):Acetate CoA-Transferase Reveal Specificity Determinants and Illustrate the Mechanism Used by Class I CoA-Transferases. Biochemistry, 51, 2012
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4EU5
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![BU of 4eu5 by Molmil](/molmil-images/mine/4eu5) | Succinyl-CoA:acetate CoA-transferase (AarCH6) in complex with CoA | Descriptor: | CHLORIDE ION, COENZYME A, Succinyl-CoA:acetate coenzyme A transferase | Authors: | Mullins, E.A, Kappock, T.J. | Deposit date: | 2012-04-25 | Release date: | 2012-10-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.743 Å) | Cite: | Crystal Structures of Acetobacter aceti Succinyl-Coenzyme A (CoA):Acetate CoA-Transferase Reveal Specificity Determinants and Illustrate the Mechanism Used by Class I CoA-Transferases. Biochemistry, 51, 2012
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4EUD
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![BU of 4eud by Molmil](/molmil-images/mine/4eud) | |
4EUC
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![BU of 4euc by Molmil](/molmil-images/mine/4euc) | Succinyl-CoA:acetate CoA-transferase (AarCH6-E294A) in complex with dethiaacetyl-CoA | Descriptor: | CHLORIDE ION, Succinyl-CoA:acetate coenzyme A transferase, [[(2R,3S,4R,5R)-5-(6-aminopurin-9-yl)-4-oxidanyl-3-phosphonooxy-oxolan-2-yl]methoxy-oxidanyl-phosphoryl] [(3R)-2,2-dimethyl-3-oxidanyl-4-oxidanylidene-4-[[3-oxidanylidene-3-(4-oxidanylidenepentylamino)propyl]amino]butyl] hydrogen phosphate | Authors: | Mullins, E.A, Kappock, T.J. | Deposit date: | 2012-04-25 | Release date: | 2012-10-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.644 Å) | Cite: | Crystal Structures of Acetobacter aceti Succinyl-Coenzyme A (CoA):Acetate CoA-Transferase Reveal Specificity Determinants and Illustrate the Mechanism Used by Class I CoA-Transferases. Biochemistry, 51, 2012
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2VVQ
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![BU of 2vvq by Molmil](/molmil-images/mine/2vvq) | Crystal structure of Mycobacterium tuberculosis ribose-5-phosphate isomerase B in complex with the inhibitor 5-deoxy-5-phospho-D- ribonate | Descriptor: | 5-O-phosphono-D-ribonic acid, RIBOSE-5-PHOSPHATE ISOMERASE B, SULFATE ION | Authors: | Kowalinski, E, Roos, A.K, Mariano, S, Salmon, L, Mowbray, S.L. | Deposit date: | 2008-06-10 | Release date: | 2008-07-01 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | D-Ribose-5-Phosphate Isomerase B from Escherichia Coli is Also a Functional D-Allose-6-Phosphate Isomerase, While the Mycobacterium Tuberculosis Enzyme is not. J.Mol.Biol., 382, 2008
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8UCU
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![BU of 8ucu by Molmil](/molmil-images/mine/8ucu) | Partial DNA termination subcomplex of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ... | Authors: | Mullins, E.A, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-09-27 | Release date: | 2023-10-11 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (2.85 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
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8UCW
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![BU of 8ucw by Molmil](/molmil-images/mine/8ucw) | Complete DNA termination subcomplex 2 of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA template, ... | Authors: | Mullins, E.A, Chazin, W.C, Eichman, B.F. | Deposit date: | 2023-09-27 | Release date: | 2023-10-11 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.64 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
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8UCV
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![BU of 8ucv by Molmil](/molmil-images/mine/8ucv) | Complete DNA termination subcomplex 1 of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA primase large subunit, ... | Authors: | Mullins, E.A, Chazin, W.C, Eichman, B.F. | Deposit date: | 2023-09-27 | Release date: | 2023-10-11 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (3.81 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
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8V5M
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![BU of 8v5m by Molmil](/molmil-images/mine/8v5m) | Tetramer core subcomplex (conformation 1) of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ... | Authors: | Mullins, E.A, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-11-30 | Release date: | 2023-12-20 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (9.22 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
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8V6J
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![BU of 8v6j by Molmil](/molmil-images/mine/8v6j) | DNA elongation complex (configuration 2) of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ... | Authors: | Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-12-01 | Release date: | 2023-12-20 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (11.11 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
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8V5O
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![BU of 8v5o by Molmil](/molmil-images/mine/8v5o) | Tetramer core subcomplex (conformation 3) of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ... | Authors: | Mullins, E.A, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-11-30 | Release date: | 2023-12-20 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (8.99 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
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8V6I
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![BU of 8v6i by Molmil](/molmil-images/mine/8v6i) | DNA elongation complex (configuration 1) of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ... | Authors: | Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-12-01 | Release date: | 2023-12-20 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (14.06 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
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8V5N
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![BU of 8v5n by Molmil](/molmil-images/mine/8v5n) | Tetramer core subcomplex (conformation 2) of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, DNA primase, ... | Authors: | Mullins, E.A, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-11-30 | Release date: | 2023-12-20 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (8.56 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
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8V6G
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![BU of 8v6g by Molmil](/molmil-images/mine/8v6g) | DNA initiation complex (configuration 1) of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ... | Authors: | Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-12-01 | Release date: | 2023-12-20 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (11.16 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
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8V6H
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![BU of 8v6h by Molmil](/molmil-images/mine/8v6h) | DNA initiation complex (configuration 2) of Xenopus laevis DNA polymerase alpha-primase | Descriptor: | 2'-DEOXYGUANOSINE-5'-TRIPHOSPHATE, DNA polymerase alpha catalytic subunit, DNA polymerase alpha subunit B, ... | Authors: | Mullins, E.A, Durie, C.L, Ohi, M.D, Chazin, W.J, Eichman, B.F. | Deposit date: | 2023-12-01 | Release date: | 2023-12-20 | Last modified: | 2024-05-29 | Method: | ELECTRON MICROSCOPY (11.11 Å) | Cite: | A mechanistic model of primer synthesis from catalytic structures of DNA polymerase alpha-primase. Nat.Struct.Mol.Biol., 31, 2024
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5UUG
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![BU of 5uug by Molmil](/molmil-images/mine/5uug) | |
5UUF
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![BU of 5uuf by Molmil](/molmil-images/mine/5uuf) | |
5UUH
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![BU of 5uuh by Molmil](/molmil-images/mine/5uuh) | |
4EU4
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![BU of 4eu4 by Molmil](/molmil-images/mine/4eu4) | |