Loading
PDBj
MenuPDBj@FacebookPDBj@TwitterPDBj@YouTubewwPDB FoundationwwPDB
RCSB PDBPDBeBMRBAdv. SearchSearch help
PDB: 601 results

8FF0
DownloadVisualize
BU of 8ff0 by Molmil
Structure of BTK kinase domain with the second-generation inhibitor tirabrutinib
Descriptor: 6-azanyl-9-[(3~{R})-1-[(~{E})-but-2-enoyl]pyrrolidin-3-yl]-7-(4-phenoxyphenyl)purin-8-one, Tyrosine-protein kinase BTK
Authors:Lin, D.Y, Andreotti, A.H.
Deposit date:2022-12-07
Release date:2023-07-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Structure of BTK kinase domain with the second-generation inhibitors acalabrutinib and tirabrutinib.
Plos One, 18, 2023
8FD9
DownloadVisualize
BU of 8fd9 by Molmil
Structure of BTK kinase domain with the second-generation inhibitor acalabrutinib
Descriptor: 4-[(4S)-8-amino-3-{(2S)-1-[(2E)-but-2-enoyl]pyrrolidin-2-yl}imidazo[1,5-a]pyrazin-1-yl]-N-(pyridin-2-yl)benzamide, BROMIDE ION, Tyrosine-protein kinase BTK
Authors:Lin, D.Y, Andreotti, A.H.
Deposit date:2022-12-02
Release date:2023-07-05
Last modified:2023-09-13
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Structure of BTK kinase domain with the second-generation inhibitors acalabrutinib and tirabrutinib.
Plos One, 18, 2023
4S0F
DownloadVisualize
BU of 4s0f by Molmil
Crystal structure of the peptidase-containing ABC transporter PCAT1 E648Q mutant complexed with ATPgS in an occluded conformation
Descriptor: ABC-type bacteriocin transporter, PHOSPHOTHIOPHOSPHORIC ACID-ADENYLATE ESTER
Authors:Lin, D.L, Huang, S, Chen, J.
Deposit date:2014-12-30
Release date:2015-07-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (5.515 Å)
Cite:Crystal structures of a polypeptide processing and secretion transporter.
Nature, 523, 2015
4RY2
DownloadVisualize
BU of 4ry2 by Molmil
Crystal structure of the peptidase-containing ABC transporter PCAT1
Descriptor: ABC-type bacteriocin transporter
Authors:Lin, D.L, Huang, S, Chen, J.
Deposit date:2014-12-13
Release date:2015-07-22
Last modified:2023-09-20
Method:X-RAY DIFFRACTION (3.611 Å)
Cite:Crystal structures of a polypeptide processing and secretion transporter.
Nature, 523, 2015
3NAW
DownloadVisualize
BU of 3naw by Molmil
Crystal structure of E. coli O157:H7 effector protein NleL
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, SULFATE ION, ...
Authors:Lin, D.Y, Chen, J.
Deposit date:2010-06-02
Release date:2010-10-27
Last modified:2011-07-13
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Biochemical and Structural Studies of a HECT-like Ubiquitin Ligase from Escherichia coli O157:H7.
J.Biol.Chem., 286, 2011
3NB2
DownloadVisualize
BU of 3nb2 by Molmil
Crystal structure of E. coli O157:H7 effector protein NleL
Descriptor: 2,3-DIHYDROXY-1,4-DITHIOBUTANE, 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, GLYCEROL, ...
Authors:Lin, D.Y, Chen, J.
Deposit date:2010-06-02
Release date:2010-10-27
Last modified:2023-09-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Biochemical and Structural Studies of a HECT-like Ubiquitin Ligase from Escherichia coli O157:H7.
J.Biol.Chem., 286, 2011
5HB7
DownloadVisualize
BU of 5hb7 by Molmil
Crystal structure of Chaetomium thermophilum Nup53 RRM
Descriptor: IODIDE ION, Nucleoporin NUP53
Authors:Lin, D.H, Stuwe, T, Hoelz, A.
Deposit date:2015-12-31
Release date:2016-04-20
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (0.819 Å)
Cite:Architecture of the symmetric core of the nuclear pore.
Science, 352, 2016
5HAZ
DownloadVisualize
BU of 5haz by Molmil
Structure of Chaetomium thermophilum Nup170 CTD
Descriptor: 1,2-ETHANEDIOL, 4-(2-HYDROXYETHYL)-1-PIPERAZINE ETHANESULFONIC ACID, Nucleoporin NUP170, ...
Authors:Lin, D.H, Hoelz, A.
Deposit date:2015-12-31
Release date:2016-04-20
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Architecture of the symmetric core of the nuclear pore.
Science, 352, 2016
5HB5
DownloadVisualize
BU of 5hb5 by Molmil
Crystal structure of Chaetomium thermophilum Nup145N APD
Descriptor: CITRATE ANION, Nucleoporin NUP145
Authors:Lin, D.H, Stuwe, T, Hoelz, A.
Deposit date:2015-12-31
Release date:2016-04-20
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Architecture of the symmetric core of the nuclear pore.
Science, 352, 2016
5HB2
DownloadVisualize
BU of 5hb2 by Molmil
Crystal Structure of Chaetomium thermophilum Nic96 SOL
Descriptor: Nucleoporin NIC96
Authors:Lin, D.H, Stuwe, T, Schilbach, S, Hoelz, A.
Deposit date:2015-12-31
Release date:2016-04-20
Last modified:2024-10-23
Method:X-RAY DIFFRACTION (3.3 Å)
Cite:Architecture of the symmetric core of the nuclear pore.
Science, 352, 2016
5HB6
DownloadVisualize
BU of 5hb6 by Molmil
Crystal structure of Chaetomium thermophilum Nup145N APD T994A mutant fused to Nup145C N
Descriptor: Nucleoporin NUP145, SULFATE ION
Authors:Lin, D.H, Stuwe, T, Hoelz, A.
Deposit date:2015-12-31
Release date:2016-04-20
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.3 Å)
Cite:Architecture of the symmetric core of the nuclear pore.
Science, 352, 2016
5HAY
DownloadVisualize
BU of 5hay by Molmil
Crystal structure of Chaetomium thermophilum Nup170 CTD Y905M L1007M L1183M V1292M mutant
Descriptor: Nucleoporin NUP170, SODIUM ION
Authors:Lin, D.H, Fan, Y, Hoelz, A.
Deposit date:2015-12-31
Release date:2016-04-20
Last modified:2024-10-09
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Architecture of the symmetric core of the nuclear pore.
Science, 352, 2016
5HB1
DownloadVisualize
BU of 5hb1 by Molmil
Crystal structure of Chaetomium thermophilum Nup170 SOL
Descriptor: Nucleoporin NUP170
Authors:Lin, D.H, Hoelz, A.
Deposit date:2015-12-31
Release date:2016-04-20
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (4.007 Å)
Cite:Architecture of the symmetric core of the nuclear pore.
Science, 352, 2016
8GMB
DownloadVisualize
BU of 8gmb by Molmil
Crystal structure of the full-length Bruton's tyrosine kinase (PH-TH domain not visible)
Descriptor: 2-[3'-(hydroxymethyl)-1-methyl-5-({5-[(2S)-2-methyl-4-(oxetan-3-yl)piperazin-1-yl]pyridin-2-yl}amino)-6-oxo[1,6-dihydro[3,4'-bipyridine]]-2'-yl]-7,7-dimethyl-3,4,7,8-tetrahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one, Tyrosine-protein kinase BTK
Authors:Lin, D.Y, Andreotti, A.H.
Deposit date:2023-03-24
Release date:2023-08-16
Last modified:2024-01-31
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Conformational heterogeneity of the BTK PHTH domain drives multiple regulatory states.
Elife, 12, 2024
5HB0
DownloadVisualize
BU of 5hb0 by Molmil
Crystal structure of Chaetomium thermophilum Nup170 CTD-Nup145N complex
Descriptor: Nucleoporin NUP145, Nucleoporin NUP170
Authors:Lin, D.H, Mobbs, G, Hoelz, A.
Deposit date:2015-12-31
Release date:2016-04-20
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (3.5 Å)
Cite:Architecture of the symmetric core of the nuclear pore.
Science, 352, 2016
5HB8
DownloadVisualize
BU of 5hb8 by Molmil
Crystal structure of Chaetomium thermophilum Nup53 RRM (space group P3121)
Descriptor: GLYCEROL, Nucleoporin NUP53, SUCCINIC ACID
Authors:Lin, D.H, Stuwe, T, Hoelz, A.
Deposit date:2015-12-31
Release date:2016-04-20
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Architecture of the symmetric core of the nuclear pore.
Science, 352, 2016
5HAX
DownloadVisualize
BU of 5hax by Molmil
Crystal structure of Chaetomium thermophilum Nup170 NTD-Nup53 complex
Descriptor: 1,2-ETHANEDIOL, GLYCEROL, Nucleoporin NUP170, ...
Authors:Lin, D.H, Mobbs, G, Hoelz, A.
Deposit date:2015-12-31
Release date:2016-04-20
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.1 Å)
Cite:Architecture of the symmetric core of the nuclear pore.
Science, 352, 2016
5HB3
DownloadVisualize
BU of 5hb3 by Molmil
Crystal structure of Chaetomium thermophilum Nic96 SOL-Nup53 complex
Descriptor: CHLORIDE ION, Nucleoporin NIC96, Nucleoporin NUP53
Authors:Lin, D.H, Stuwe, T, Hoelz, A.
Deposit date:2015-12-31
Release date:2016-04-20
Last modified:2024-03-06
Method:X-RAY DIFFRACTION (2.65 Å)
Cite:Architecture of the symmetric core of the nuclear pore.
Science, 352, 2016
6B4F
DownloadVisualize
BU of 6b4f by Molmil
Crystal structure of human Gle1 CTD-Nup42 GBM complex
Descriptor: CHLORIDE ION, Nucleoporin GLE1, Nucleoporin like 2, ...
Authors:Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A.
Deposit date:2017-09-26
Release date:2018-06-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.811 Å)
Cite:Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Nat Commun, 9, 2018
6B4K
DownloadVisualize
BU of 6b4k by Molmil
Crystal structure of human DDX19B(AMPPNP)
Descriptor: ATP-dependent RNA helicase DDX19B, MAGNESIUM ION, MALONATE ION, ...
Authors:Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A.
Deposit date:2017-09-26
Release date:2018-06-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Nat Commun, 9, 2018
6B4H
DownloadVisualize
BU of 6b4h by Molmil
Crystal structure of Chaetomium thermophilum Gle1 CTD-Nup42 GBM-IP6 complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, INOSITOL HEXAKISPHOSPHATE, Nucleoporin AMO1, ...
Authors:Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A.
Deposit date:2017-09-26
Release date:2018-06-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.17 Å)
Cite:Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Nat Commun, 9, 2018
6B4E
DownloadVisualize
BU of 6b4e by Molmil
Crystal structure of Saccharomyces cerevisiae Gle1 CTD-Nup42 GBM complex
Descriptor: 1,2-ETHANEDIOL, Nucleoporin GLE1, Nucleoporin NUP42, ...
Authors:Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A.
Deposit date:2017-09-26
Release date:2018-06-20
Last modified:2023-10-04
Method:X-RAY DIFFRACTION (1.75 Å)
Cite:Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Nat Commun, 9, 2018
6B4J
DownloadVisualize
BU of 6b4j by Molmil
Crystal structure of human Gle1 CTD-Nup42 GBM-DDX19B(AMPPNP) complex
Descriptor: ATP-dependent RNA helicase DDX19B, MAGNESIUM ION, Nucleoporin GLE1, ...
Authors:Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A.
Deposit date:2017-09-26
Release date:2018-06-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.4 Å)
Cite:Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Nat Commun, 9, 2018
6B4I
DownloadVisualize
BU of 6b4i by Molmil
Crystal structure of human Gle1 CTD-Nup42 GBM-DDX19B(ADP) complex
Descriptor: ADENOSINE-5'-DIPHOSPHATE, ATP-dependent RNA helicase DDX19B, Nucleoporin GLE1, ...
Authors:Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A.
Deposit date:2017-09-26
Release date:2018-06-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (3.619 Å)
Cite:Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Nat Commun, 9, 2018
6B4G
DownloadVisualize
BU of 6b4g by Molmil
Crystal structure of Chaetomium thermophilum Gle1 CTD-Nup42 GBM complex
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Nucleoporin AMO1, Nucleoporin GLE1
Authors:Lin, D.H, Correia, A.R, Cai, S.W, Huber, F.M, Jette, C.A, Hoelz, A.
Deposit date:2017-09-26
Release date:2018-06-20
Last modified:2024-03-13
Method:X-RAY DIFFRACTION (2.648 Å)
Cite:Structural and functional analysis of mRNA export regulation by the nuclear pore complex.
Nat Commun, 9, 2018

226707

건을2024-10-30부터공개중

PDB statisticsPDBj update infoContact PDBjnumon