6LU8
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![BU of 6lu8 by Molmil](/molmil-images/mine/6lu8) | Cryo-EM structure of a human pre-60S ribosomal subunit - state A | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. | Deposit date: | 2020-01-26 | Release date: | 2020-08-26 | Method: | ELECTRON MICROSCOPY (3.13 Å) | Cite: | Structural snapshots of human pre-60S ribosomal particles before and after nuclear export. Nat Commun, 11, 2020
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8ERI
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![BU of 8eri by Molmil](/molmil-images/mine/8eri) | |
6LQM
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![BU of 6lqm by Molmil](/molmil-images/mine/6lqm) | Cryo-EM structure of a pre-60S ribosomal subunit - state C | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. | Deposit date: | 2020-01-14 | Release date: | 2020-08-26 | Method: | ELECTRON MICROSCOPY (3.09 Å) | Cite: | Structural snapshots of human pre-60S ribosomal particles before and after nuclear export. Nat Commun, 11, 2020
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6LSS
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![BU of 6lss by Molmil](/molmil-images/mine/6lss) | Cryo-EM structure of a pre-60S ribosomal subunit - state preA | Descriptor: | 28S rRNA, 5S rRNA, 60S ribosomal protein L11, ... | Authors: | Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. | Deposit date: | 2020-01-20 | Release date: | 2020-08-26 | Method: | ELECTRON MICROSCOPY (3.23 Å) | Cite: | Structural snapshots of human pre-60S ribosomal particles before and after nuclear export. Nat Commun, 11, 2020
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8FEC
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![BU of 8fec by Molmil](/molmil-images/mine/8fec) | Structure of J-PKAc chimera complexed with Aplithianine derivative | Descriptor: | 6-[(6P)-6-(4-bromo-1-methyl-1H-imidazol-5-yl)-2,3-dihydro-4H-1,4-thiazin-4-yl]-7H-purine, DnaJ homolog subfamily B member 1,cAMP-dependent protein kinase catalytic subunit alpha, cAMP-dependent protein kinase inhibitor alpha | Authors: | Du, L, Wilson, B.A.P, Li, N, Martinez Fiesco, J.A, Dalilian, M, Wang, D, Smith, E.A, Wamiru, A, Goncharova, E.I, Zhang, P, O'Keefe, B.R. | Deposit date: | 2022-12-06 | Release date: | 2023-10-18 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.7 Å) | Cite: | Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases. J.Nat.Prod., 86, 2023
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8FE2
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![BU of 8fe2 by Molmil](/molmil-images/mine/8fe2) | Structure of J-PKAc chimera complexed with Aplithianine A | Descriptor: | 6-[(6M)-6-(1-methyl-1H-imidazol-5-yl)-2,3-dihydro-4H-1,4-thiazin-4-yl]-9H-purine, DnaJ homolog subfamily B member 1, cAMP-dependent protein kinase catalytic subunit alpha, ... | Authors: | Du, L, Wilson, B.A.P, Li, N, Dalilian, M, Wang, D, Martinez Fiesco, J.A, Smith, E.A, Wamiru, A, Goncharova, E.I, Zhang, P, O'Keefe, B.R. | Deposit date: | 2022-12-05 | Release date: | 2023-10-18 | Last modified: | 2024-05-01 | Method: | X-RAY DIFFRACTION (2.34 Å) | Cite: | Discovery and Synthesis of a Naturally Derived Protein Kinase Inhibitor that Selectively Inhibits Distinct Classes of Serine/Threonine Kinases. J.Nat.Prod., 86, 2023
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1F90
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![BU of 1f90 by Molmil](/molmil-images/mine/1f90) | FAB FRAGMENT OF MONOCLONAL ANTIBODY (LNKB-2) AGAINST HUMAN INTERLEUKIN-2 IN COMPLEX WITH ANTIGENIC PEPTIDE | Descriptor: | ANTIGENIC NONAPEPTIDE, FAB FRAGMENT OF MONOCLONAL ANTIBODY | Authors: | Afonin, P.V, Fokin, A.V, Tsigannik, I.N, Mikhailova, I.Y, Onoprienko, L.V, Mikhaleva, I.I, Ivanov, V.T, Mareeva, T.Y, Nesmeyanov, V.A, Li, N, Duax, W.L, Pletnev, V.Z. | Deposit date: | 2000-07-06 | Release date: | 2001-07-11 | Last modified: | 2018-04-04 | Method: | X-RAY DIFFRACTION (2.6 Å) | Cite: | Crystal structure of an anti-interleukin-2 monoclonal antibody Fab complexed with an antigenic nonapeptide. Protein Sci., 10, 2001
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6LSR
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![BU of 6lsr by Molmil](/molmil-images/mine/6lsr) | Cryo-EM structure of a pre-60S ribosomal subunit - state B | Descriptor: | 28S rRNA, 5.8S rRNA, 5S rRNA, ... | Authors: | Liang, X, Zuo, M, Zhang, Y, Li, N, Ma, C, Dong, M, Gao, N. | Deposit date: | 2020-01-20 | Release date: | 2020-08-26 | Method: | ELECTRON MICROSCOPY (3.13 Å) | Cite: | Structural snapshots of human pre-60S ribosomal particles before and after nuclear export. Nat Commun, 11, 2020
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4Q9Q
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![BU of 4q9q by Molmil](/molmil-images/mine/4q9q) | Crystal structure of an RNA aptamer bound to bromo-ligand analog in complex with Fab | Descriptor: | (5Z)-5-(3-bromobenzylidene)-2,3-dimethyl-3,5-dihydro-4H-imidazol-4-one, Fab BL3-6, HEAVY CHAIN, ... | Authors: | Huang, H, Suslov, N.B, Li, N.-S, Shelke, S.A, Evans, M.E, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. | Deposit date: | 2014-05-01 | Release date: | 2014-06-18 | Last modified: | 2017-07-26 | Method: | X-RAY DIFFRACTION (2.45 Å) | Cite: | A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore. Nat.Chem.Biol., 10, 2014
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8TMW
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![BU of 8tmw by Molmil](/molmil-images/mine/8tmw) | |
8TMV
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![BU of 8tmv by Molmil](/molmil-images/mine/8tmv) | |
4Q9R
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![BU of 4q9r by Molmil](/molmil-images/mine/4q9r) | Crystal structure of an RNA aptamer bound to trifluoroethyl-ligand analog in complex with Fab | Descriptor: | (5Z)-5-(3,5-difluoro-4-hydroxybenzylidene)-2-methyl-3-(2,2,2-trifluoroethyl)-3,5-dihydro-4H-imidazol-4-one, Fab BL3-6, HEAVY CHAIN, ... | Authors: | Huang, H, Suslov, N.B, Li, N.-S, Shelke, S.A, Evans, M.E, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. | Deposit date: | 2014-05-01 | Release date: | 2014-06-18 | Last modified: | 2017-07-26 | Method: | X-RAY DIFFRACTION (3.12 Å) | Cite: | A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore. Nat.Chem.Biol., 10, 2014
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8WPK
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![BU of 8wpk by Molmil](/molmil-images/mine/8wpk) | Structure of monkeypox virus polymerase complex F8-A22-E4-H5 with exgenous DNA | Descriptor: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, DNA polymerase, DNA polymerase processivity factor, ... | Authors: | Wang, X, Li, N, Gao, N. | Deposit date: | 2023-10-10 | Release date: | 2023-11-29 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5. Mol.Cell, 83, 2023
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8WPE
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![BU of 8wpe by Molmil](/molmil-images/mine/8wpe) | Structure of monkeypox virus polymerase complex F8-A22-E4-H5 (tag-free A22) with exogenous DNA | Descriptor: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, A22R DNA polymerase processivity factor, DNA polymerase, ... | Authors: | Wang, X, Li, N, Gao, N. | Deposit date: | 2023-10-10 | Release date: | 2023-11-29 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (2.7 Å) | Cite: | Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5. Mol.Cell, 83, 2023
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8WPP
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![BU of 8wpp by Molmil](/molmil-images/mine/8wpp) | Structure of monkeypox virus polymerase complex F8-A22-E4-H5 with endogenous DNA | Descriptor: | A22R DNA polymerase processivity factor, DNA polymerase, E4R Uracil-DNA glycosylase, ... | Authors: | Wang, X, Li, N, Gao, N. | Deposit date: | 2023-10-10 | Release date: | 2023-11-29 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3.1 Å) | Cite: | Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5. Mol.Cell, 83, 2023
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8WPF
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![BU of 8wpf by Molmil](/molmil-images/mine/8wpf) | Structure of monkeypox virus polymerase complex F8-A22-E4-H5 with exogenous DNA bearing one abasic site | Descriptor: | 2',3'-DIDEOXY-THYMIDINE-5'-TRIPHOSPHATE, A22R DNA polymerase processivity factor, DNA polymerase, ... | Authors: | Wang, X, Li, N, Gao, N. | Deposit date: | 2023-10-10 | Release date: | 2023-11-29 | Last modified: | 2023-12-27 | Method: | ELECTRON MICROSCOPY (3 Å) | Cite: | Structural insights into the assembly and mechanism of mpox virus DNA polymerase complex F8-A22-E4-H5. Mol.Cell, 83, 2023
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1WZA
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![BU of 1wza by Molmil](/molmil-images/mine/1wza) | |
5YRP
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![BU of 5yrp by Molmil](/molmil-images/mine/5yrp) | Crystal structure of the EAL domain of Mycobacterium smegmatis DcpA | Descriptor: | MAGNESIUM ION, Sensory box/response regulator | Authors: | Chen, H.J, li, N, Luo, Y, Jiang, Y.L, Zhou, C.Z, Chen, Y, Li, Q. | Deposit date: | 2017-11-09 | Release date: | 2018-05-09 | Last modified: | 2023-11-22 | Method: | X-RAY DIFFRACTION (2.99 Å) | Cite: | The GDP-switched GAF domain of DcpA modulates the concerted synthesis/hydrolysis of c-di-GMP inMycobacterium smegmatis. Biochem. J., 475, 2018
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3J3T
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![BU of 3j3t by Molmil](/molmil-images/mine/3j3t) | Structural dynamics of the MecA-ClpC complex revealed by cryo-EM | Descriptor: | Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB | Authors: | Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N. | Deposit date: | 2013-04-18 | Release date: | 2013-05-15 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (9 Å) | Cite: | Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine. J.Biol.Chem., 288, 2013
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3J3R
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![BU of 3j3r by Molmil](/molmil-images/mine/3j3r) | Structural dynamics of the MecA-ClpC complex revealed by cryo-EM | Descriptor: | Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB | Authors: | Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N. | Deposit date: | 2013-04-18 | Release date: | 2013-05-15 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (9.4 Å) | Cite: | Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine J.Biol.Chem., 288, 2013
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3J3U
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![BU of 3j3u by Molmil](/molmil-images/mine/3j3u) | Structural dynamics of the MecA-ClpC complex revealed by cryo-EM | Descriptor: | Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB | Authors: | Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N. | Deposit date: | 2013-04-18 | Release date: | 2013-05-15 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (10 Å) | Cite: | Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine. J.Biol.Chem., 288, 2013
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3J3S
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![BU of 3j3s by Molmil](/molmil-images/mine/3j3s) | Structural dynamics of the MecA-ClpC complex revealed by cryo-EM | Descriptor: | Adapter protein MecA 1, Negative regulator of genetic competence ClpC/MecB | Authors: | Liu, J, Mei, Z, Li, N, Qi, Y, Xu, Y, Shi, Y, Wang, F, Lei, J, Gao, N. | Deposit date: | 2013-04-18 | Release date: | 2013-05-15 | Last modified: | 2024-03-20 | Method: | ELECTRON MICROSCOPY (11 Å) | Cite: | Structural dynamics of the MecA-ClpC complex: a type II AAA+ protein unfolding machine. J.Biol.Chem., 288, 2013
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4CSU
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![BU of 4csu by Molmil](/molmil-images/mine/4csu) | Cryo-EM structures of the 50S ribosome subunit bound with ObgE | Descriptor: | 23S RRNA, 50S RIBOSOMAL PROTEIN L1, 50S RIBOSOMAL PROTEIN L11, ... | Authors: | Feng, B, Mandava, C.S, Guo, Q, Wang, J, Cao, W, Li, N, Zhang, Y, Zhang, Y, Wang, Z, Wu, J, Sanyal, S, Lei, J, Gao, N. | Deposit date: | 2014-03-10 | Release date: | 2014-06-04 | Last modified: | 2024-05-08 | Method: | ELECTRON MICROSCOPY (5.5 Å) | Cite: | Structural and Functional Insights Into the Mode of Action of a Universally Conserved Obg Gtpase. Plos Biol., 12, 2014
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4KZE
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![BU of 4kze by Molmil](/molmil-images/mine/4kze) | Crystal structure of an RNA aptamer in complex with Fab | Descriptor: | BL3-6 Fab antibody, heavy chain, light chain, ... | Authors: | Huang, H, Suslov, N.B, Li, N, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. | Deposit date: | 2013-05-29 | Release date: | 2014-06-18 | Last modified: | 2014-07-30 | Method: | X-RAY DIFFRACTION (2.404 Å) | Cite: | A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore. Nat.Chem.Biol., 10, 2014
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4KZD
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![BU of 4kzd by Molmil](/molmil-images/mine/4kzd) | Crystal structure of an RNA aptamer in complex with fluorophore and Fab | Descriptor: | 4-(3,5-difluoro-4-hydroxybenzyl)-1,2-dimethyl-1H-imidazol-5-ol, BL3-6 Fab antibody, heavy chain, ... | Authors: | Huang, H, Suslov, N.B, Li, N, Koldobskaya, Y, Rice, P.A, Piccirilli, J.A. | Deposit date: | 2013-05-29 | Release date: | 2014-06-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.186 Å) | Cite: | A G-quadruplex-containing RNA activates fluorescence in a GFP-like fluorophore. Nat.Chem.Biol., 10, 2014
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