1PJ5
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1pj5 by Molmil](/molmil-images/mine/1pj5) | Crystal structure of dimethylglycine oxidase of Arthrobacter globiformis in complex with acetate | Descriptor: | ACETATE ION, FLAVIN-ADENINE DINUCLEOTIDE, N,N-dimethylglycine oxidase, ... | Authors: | Leys, D, Basran, J, Scrutton, N.S. | Deposit date: | 2003-06-01 | Release date: | 2003-10-07 | Last modified: | 2011-07-13 | Method: | X-RAY DIFFRACTION (1.61 Å) | Cite: | Channelling and formation of 'active' formaldehyde in dimethylglycine oxidase. Embo J., 22, 2003
|
|
1PJ7
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1pj7 by Molmil](/molmil-images/mine/1pj7) | Structure of dimethylglycine oxidase of Arthrobacter globiformis in complex with folinic acid | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, N,N-dimethylglycine oxidase, N-[4-({[(6S)-2-amino-5-formyl-4-oxo-3,4,5,6,7,8-hexahydropteridin-6-yl]methyl}amino)benzoyl]-L-glutamic acid, ... | Authors: | Leys, D, Basran, J, Scrutton, N.S. | Deposit date: | 2003-06-01 | Release date: | 2003-10-07 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (2.1 Å) | Cite: | Channelling and formation of 'active' formaldehyde in dimethylglycine oxidase. Embo J., 22, 2003
|
|
1O97
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1o97 by Molmil](/molmil-images/mine/1o97) | Structure of electron transferring flavoprotein from Methylophilus methylotrophus, recognition loop removed by limited proteolysis | Descriptor: | ADENOSINE MONOPHOSPHATE, ELECTRON TRANSFERRING FLAVOPROTEIN ALPHA-SUBUNIT, ELECTRON TRANSFERRING FLAVOPROTEIN BETA-SUBUNIT, ... | Authors: | Leys, D, Basran, J, Talfournier, F, Sutcliffe, M.J, Scrutton, N.S. | Deposit date: | 2002-12-11 | Release date: | 2003-02-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (1.6 Å) | Cite: | Extensive Conformational Sampling in a Ternary Electron Transfer Complex. Nat.Struct.Biol., 10, 2003
|
|
1O95
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1o95 by Molmil](/molmil-images/mine/1o95) | Ternary complex between trimethylamine dehydrogenase and electron transferring flavoprotein | Descriptor: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ELECTRON TRANSFER FLAVOPROTEIN ALPHA-SUBUNIT, ... | Authors: | Leys, D, Basran, J, Talfournier, F, Sutcliffe, M.J, Scrutton, N.S. | Deposit date: | 2002-12-11 | Release date: | 2003-02-06 | Last modified: | 2013-09-18 | Method: | X-RAY DIFFRACTION (3.7 Å) | Cite: | Extensive Conformational Sampling in a Ternary Electron Transfer Complex. Nat.Struct.Biol., 10, 2003
|
|
1O94
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1o94 by Molmil](/molmil-images/mine/1o94) | Ternary complex between trimethylamine dehydrogenase and electron transferring flavoprotein | Descriptor: | ADENOSINE MONOPHOSPHATE, ADENOSINE-5'-DIPHOSPHATE, ELECTRON TRANSFER FLAVOPROTEIN ALPHA-SUBUNIT, ... | Authors: | Leys, D, Basran, J, Talfournier, F, Sutcliffe, M.J, Scrutton, N.S. | Deposit date: | 2002-12-11 | Release date: | 2003-02-06 | Last modified: | 2023-12-13 | Method: | X-RAY DIFFRACTION (2 Å) | Cite: | Extensive Conformational Sampling in a Ternary Electron Transfer Complex. Nat.Struct.Biol., 10, 2003
|
|
1O96
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1o96 by Molmil](/molmil-images/mine/1o96) | Structure of electron transferring flavoprotein for Methylophilus methylotrophus. | Descriptor: | ADENOSINE MONOPHOSPHATE, ELECTRON TRANSFERRING FLAVOPROTEIN ALPHA-SUBUNIT, ELECTRON TRANSFERRING FLAVOPROTEIN BETA-SUBUNIT, ... | Authors: | Leys, D, Basran, J, Talfournier, F, Sutcliffe, M.J, Scrutton, N.S. | Deposit date: | 2002-12-11 | Release date: | 2003-02-06 | Last modified: | 2024-05-08 | Method: | X-RAY DIFFRACTION (3.1 Å) | Cite: | Extensive Conformational Sampling in a Ternary Electron Transfer Complex. Nat.Struct.Biol., 10, 2003
|
|
1DW0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1dw0 by Molmil](/molmil-images/mine/1dw0) | STRUCTURE OF OXIDIZED SHP, AN OXYGEN BINDING CYTOCHROME C | Descriptor: | CYTOCHROME C, HEME C, SULFATE ION | Authors: | Leys, D, Backers, K, Meyer, T.E, Hagen, W.R, Cusanovich, M.A, Van Beeumen, J.J. | Deposit date: | 2000-01-24 | Release date: | 2000-06-28 | Last modified: | 2021-03-03 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Crystal structures of an oxygen-binding cytochrome c from Rhodobacter sphaeroides. J.Biol.Chem., 275, 2000
|
|
2FWT
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 2fwt by Molmil](/molmil-images/mine/2fwt) | Crystal structure of DHC purified from Rhodobacter sphaeroides | Descriptor: | DHC, diheme cytochrome c, HEME C | Authors: | Leys, D. | Deposit date: | 2006-02-03 | Release date: | 2006-05-23 | Last modified: | 2019-10-02 | Method: | X-RAY DIFFRACTION (1.85 Å) | Cite: | Structural and Functional Studies on DHC, the Diheme Cytochrome c from Rhodobacter sphaeroides, and Its Interaction with SHP, the sphaeroides Heme Protein Biochemistry, 45, 2006
|
|
1PJ6
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1pj6 by Molmil](/molmil-images/mine/1pj6) | Crystal structure of dimethylglycine oxidase of Arthrobacter globiformis in complex with folic acid | Descriptor: | FLAVIN-ADENINE DINUCLEOTIDE, FOLIC ACID, N,N-dimethylglycine oxidase, ... | Authors: | Leys, D, Basran, J, Scrutton, N.S. | Deposit date: | 2003-06-01 | Release date: | 2003-10-07 | Last modified: | 2023-08-16 | Method: | X-RAY DIFFRACTION (1.65 Å) | Cite: | Channelling and formation of 'active' formaldehyde in dimethylglycine oxidase. Embo J., 22, 2003
|
|
4O4P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4o4p by Molmil](/molmil-images/mine/4o4p) | Structure of P450 BM3 A82F F87V in complex with S-omeprazol | Descriptor: | 6-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole, Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Leys, D. | Deposit date: | 2013-12-19 | Release date: | 2014-01-29 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (1.83 Å) | Cite: | Human P450-like oxidation of diverse proton pump inhibitor drugs by 'gatekeeper' mutants of flavocytochrome P450 BM3. Biochem.J., 460, 2014
|
|
4OQR
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4oqr by Molmil](/molmil-images/mine/4oqr) | Structure of a CYP105AS1 mutant in complex with compactin | Descriptor: | CYP105AS1, Mevastatin, Compactin, ... | Authors: | Leys, D. | Deposit date: | 2014-02-10 | Release date: | 2015-02-18 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.81 Å) | Cite: | Single-step fermentative production of the cholesterol-lowering drug pravastatin via reprogramming of Penicillium chrysogenum. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
1M1P
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1m1p by Molmil](/molmil-images/mine/1m1p) | P21 crystal structure of the tetraheme cytochrome c3 from Shewanella oneidensis MR1 | Descriptor: | HEME C, SULFATE ION, Small tetraheme cytochrome c | Authors: | Leys, D, Meyer, T.E, Tsapin, A.I, Nealson, K.H, Cusanovich, M.A, Van Beeumen, J.J. | Deposit date: | 2002-06-20 | Release date: | 2002-08-14 | Last modified: | 2024-04-03 | Method: | X-RAY DIFFRACTION (1.55 Å) | Cite: | Crystal structures at atomic resolution reveal the novel concept of 'electron-harvesting' as a role for the small tetraheme cytochrome c J.Biol.Chem., 277, 2002
|
|
4OQS
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4oqs by Molmil](/molmil-images/mine/4oqs) | Crystal structure of CYP105AS1 | Descriptor: | CYP105AS1, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Leys, D. | Deposit date: | 2014-02-10 | Release date: | 2015-02-18 | Last modified: | 2023-09-20 | Method: | X-RAY DIFFRACTION (2.04 Å) | Cite: | Single-step fermentative production of the cholesterol-lowering drug pravastatin via reprogramming of Penicillium chrysogenum. Proc.Natl.Acad.Sci.USA, 112, 2015
|
|
1N4G
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1n4g by Molmil](/molmil-images/mine/1n4g) | Structure of CYP121, a Mycobacterial P450, in Complex with Iodopyrazole | Descriptor: | 4-IODOPYRAZOLE, Cytochrome P450 121, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Leys, D, Mowat, C.G, McLean, K.J, Richmond, A, Chapman, S.K, Walkinshaw, M.D, Munro, A.W, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2002-10-31 | Release date: | 2003-02-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.8 Å) | Cite: | Atomic structure of Mycobacterium tuberculosis CYP121 to 1.06 A reveals novel features of cytochrome P450. J.Biol.Chem., 278, 2003
|
|
1N40
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1n40 by Molmil](/molmil-images/mine/1n40) | Atomic structure of CYP121, a mycobacterial P450 | Descriptor: | Cytochrome P450 121, OXYGEN MOLECULE, PROTOPORPHYRIN IX CONTAINING FE, ... | Authors: | Leys, D, Mowat, C.G, McLean, K.J, Richmond, A, Chapman, S.K, Walkinshaw, M.D, Munro, A.W, TB Structural Genomics Consortium (TBSGC) | Deposit date: | 2002-10-30 | Release date: | 2003-02-04 | Last modified: | 2024-02-14 | Method: | X-RAY DIFFRACTION (1.06 Å) | Cite: | Atomic structure of Mycobacterium tuberculosis CYP121 to 1.06 A reveals novel features of cytochrome P450. J.Biol.Chem., 278, 2003
|
|
1M1R
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1m1r by Molmil](/molmil-images/mine/1m1r) | Reduced p222 crystal structure of the tetraheme cytochrome c of Shewanella oneidensis MR1 | Descriptor: | HEME C, SMALL tetraheme cytochrome c, SULFATE ION | Authors: | Leys, D, Meyer, T.E, Tsapin, A.I, Nealson, K.H, Cusanovich, M.A, Van Beeumen, J.J. | Deposit date: | 2002-06-20 | Release date: | 2002-08-14 | Last modified: | 2021-03-03 | Method: | X-RAY DIFFRACTION (1.02 Å) | Cite: | Crystal structures at atomic resolution reveal the novel concept of 'electron-harvesting' as a role for the small tetraheme cytochrome c J.Biol.Chem., 277, 2002
|
|
1M1Q
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 1m1q by Molmil](/molmil-images/mine/1m1q) | P222 oxidized structure of the tetraheme cytochrome c from Shewanella oneidensis MR1 | Descriptor: | HEME C, SULFATE ION, small tetraheme cytochrome c | Authors: | Leys, D, Meyer, T.E, Tsapin, A.I, Nealson, K.H, Cusanovich, M.A, Van Beeumen, J.J. | Deposit date: | 2002-06-20 | Release date: | 2002-08-14 | Last modified: | 2021-03-03 | Method: | X-RAY DIFFRACTION (0.97 Å) | Cite: | Crystal structures at atomic resolution reveal the novel concept of 'electron-harvesting' as a role for the small tetraheme cytochrome c J.Biol.Chem., 277, 2002
|
|
3EKB
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 3ekb by Molmil](/molmil-images/mine/3ekb) | |
4L54
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4l54 by Molmil](/molmil-images/mine/4l54) | Structure of cytochrome P450 OleT, ligand-free | Descriptor: | PROTOPORPHYRIN IX CONTAINING FE, Terminal olefin-forming fatty acid decarboxylase | Authors: | Leys, D. | Deposit date: | 2013-06-10 | Release date: | 2013-11-27 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.3 Å) | Cite: | Structure and Biochemical Properties of the Alkene Producing Cytochrome P450 OleTJE (CYP152L1) from the Jeotgalicoccus sp. 8456 Bacterium. J.Biol.Chem., 289, 2014
|
|
4KEW
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4kew by Molmil](/molmil-images/mine/4kew) | structure of the A82F BM3 heme domain in complex with omeprazole | Descriptor: | 6-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole, Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Leys, D. | Deposit date: | 2013-04-26 | Release date: | 2013-07-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.89 Å) | Cite: | Key Mutations Alter the Cytochrome P450 BM3 Conformational Landscape and Remove Inherent Substrate Bias. J.Biol.Chem., 288, 2013
|
|
4KF0
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4kf0 by Molmil](/molmil-images/mine/4kf0) | Structure of the A82F P450 BM3 heme domain | Descriptor: | Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Leys, D. | Deposit date: | 2013-04-26 | Release date: | 2013-07-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.45 Å) | Cite: | Key Mutations Alter the Cytochrome P450 BM3 Conformational Landscape and Remove Inherent Substrate Bias. J.Biol.Chem., 288, 2013
|
|
4KEY
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4key by Molmil](/molmil-images/mine/4key) | Structure of P450 BM3 A82F F87V in complex with omeprazole | Descriptor: | 6-methoxy-2-{[(4-methoxy-3,5-dimethylpyridin-2-yl)methyl]sulfanyl}-1H-benzimidazole, Bifunctional P-450/NADPH-P450 reductase, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Leys, D. | Deposit date: | 2013-04-26 | Release date: | 2013-07-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (2.05 Å) | Cite: | Key Mutations Alter the Cytochrome P450 BM3 Conformational Landscape and Remove Inherent Substrate Bias. J.Biol.Chem., 288, 2013
|
|
4KF2
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 4kf2 by Molmil](/molmil-images/mine/4kf2) | Structure of the P4509 BM3 A82F F87V heme domain | Descriptor: | Bifunctional P-450/NADPH-P450 reductase, IMIDAZOLE, PROTOPORPHYRIN IX CONTAINING FE | Authors: | Leys, D. | Deposit date: | 2013-04-26 | Release date: | 2013-07-10 | Last modified: | 2024-02-28 | Method: | X-RAY DIFFRACTION (1.82 Å) | Cite: | Key Mutations Alter the Cytochrome P450 BM3 Conformational Landscape and Remove Inherent Substrate Bias. J.Biol.Chem., 288, 2013
|
|
6TIL
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6til by Molmil](/molmil-images/mine/6til) | |
6TIO
![Download](/newweb/media/icons/dl.png) ![Visualize](/newweb/media/icons/hoh_3d.png)
![BU of 6tio by Molmil](/molmil-images/mine/6tio) | |