3DB8
 
 | | Crystal structure of an activated (Thr->Asp) Polo-like kinase 1 (Plk1) catalytic domain in complex with Compound 041 | | Descriptor: | 3-[3-chloro-5-(5-{[(1S)-1-phenylethyl]amino}isoxazolo[5,4-c]pyridin-3-yl)phenyl]propan-1-ol, Polo-like kinase 1 | | Authors: | Elling, R.A, Hanan, E.J, Lew, W, Romanowski, M.J. | | Deposit date: | 2008-05-30 | | Release date: | 2008-10-07 | | Last modified: | 2023-08-30 | | Method: | X-RAY DIFFRACTION (3.15 Å) | | Cite: | Design and synthesis of 2-amino-isoxazolopyridines as Polo-like kinase inhibitors.
Bioorg.Med.Chem.Lett., 18, 2008
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1W9R
 | | Solution Structure of Choline Binding Protein A, Domain R2, the Major Adhesin of Streptococcus pneumoniae | | Descriptor: | CHOLINE BINDING PROTEIN A | | Authors: | Luo, R, Mann, B, Lewis, W.S, Rowe, A, Heath, R, Stewart, M.L, Hamburger, A.E, Bjorkman, P.J, Sivakolundu, S, Lacy, E.R, Tuomanen, E, Kriwacki, R.W. | | Deposit date: | 2004-10-15 | | Release date: | 2005-02-22 | | Last modified: | 2024-05-15 | | Method: | SOLUTION NMR | | Cite: | Solution Structure of Choline Binding Protein A, the Major Adhesin of Streptococcus Pneumoniae
Embo J., 24, 2005
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7S9E
 | | Cryo-EM Structure of dolphin Prestin: Inhibited II (Sulfate +Salicylate) state | | Descriptor: | 2-HYDROXYBENZOIC ACID, Prestin | | Authors: | Bavi, N, Clark, M.D, Contreras, G.F, Shen, R, Reddy, B.G, Milewski, W, Perozo, E. | | Deposit date: | 2021-09-20 | | Release date: | 2021-11-03 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.7 Å) | | Cite: | The conformational cycle of prestin underlies outer-hair cell electromotility.
Nature, 600, 2021
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7S8X
 | | Cryo-EM Structure of dolphin Prestin: Sensor Up (compact) state | | Descriptor: | Prestin | | Authors: | Bavi, N, Clark, M.D, Contreras, G.F, Shen, R, Reddy, B.G, Milewski, W, Perozo, E. | | Deposit date: | 2021-09-20 | | Release date: | 2021-11-03 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.3 Å) | | Cite: | The conformational cycle of prestin underlies outer-hair cell electromotility.
Nature, 600, 2021
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7S9C
 | | Cryo-EM Structure of dolphin Prestin: Sensor Down II (Expanded II) state | | Descriptor: | Prestin | | Authors: | Bavi, N, Clark, M.D, Contreras, G.F, Shen, R, Reddy, B.G, Milewski, W, Perozo, E. | | Deposit date: | 2021-09-20 | | Release date: | 2021-11-03 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (6.7 Å) | | Cite: | The conformational cycle of prestin underlies outer-hair cell electromotility.
Nature, 600, 2021
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7S9D
 | | Cryo-EM Structure of dolphin Prestin: Intermediate state | | Descriptor: | Prestin | | Authors: | Bavi, N, Clark, M.D, Contreras, G.F, Shen, R, Reddy, B.G, Milewski, W, Perozo, E. | | Deposit date: | 2021-09-20 | | Release date: | 2021-11-03 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (4.6 Å) | | Cite: | The conformational cycle of prestin underlies outer-hair cell electromotility.
Nature, 600, 2021
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7S9A
 | | Cryo-EM Structure of dolphin Prestin: Inhibited I (Chloride + Salicylate) | | Descriptor: | 2-HYDROXYBENZOIC ACID, Prestin | | Authors: | Bavi, N, Clark, M.D, Contreras, G.F, Shen, R, Reddy, B.G, Milewski, W, Perozo, E. | | Deposit date: | 2021-09-20 | | Release date: | 2021-11-03 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (3.8 Å) | | Cite: | The conformational cycle of prestin underlies outer-hair cell electromotility.
Nature, 600, 2021
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7S9B
 | | Cryo-EM Structure of dolphin Prestin: Sensor Down I (Expanded) state | | Descriptor: | Prestin | | Authors: | Bavi, N, Clark, M.D, Contreras, G.F, Shen, R, Reddy, B.G, Milewski, W, Perozo, E. | | Deposit date: | 2021-09-20 | | Release date: | 2021-11-03 | | Last modified: | 2024-06-05 | | Method: | ELECTRON MICROSCOPY (4.2 Å) | | Cite: | The conformational cycle of prestin underlies outer-hair cell electromotility.
Nature, 600, 2021
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1G6T
 | | STRUCTURE OF EPSP SYNTHASE LIGANDED WITH SHIKIMATE-3-PHOSPHATE | | Descriptor: | EPSP SYNTHASE, FORMIC ACID, PHOSPHATE ION, ... | | Authors: | Schonbrunn, E, Eschenburg, S, Shuttleworth, W, Schloss, J.V, Amrhein, N, Evans, J.N.S, Kabsch, W. | | Deposit date: | 2000-11-07 | | Release date: | 2001-02-07 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.6 Å) | | Cite: | Interaction of the herbicide glyphosate with its target enzyme 5-enolpyruvylshikimate 3-phosphate synthase in atomic detail.
Proc.Natl.Acad.Sci.USA, 98, 2001
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1G6S
 | | STRUCTURE OF EPSP SYNTHASE LIGANDED WITH SHIKIMATE-3-PHOSPHATE AND GLYPHOSATE | | Descriptor: | EPSP SYNTHASE, FORMIC ACID, GLYPHOSATE, ... | | Authors: | Schonbrunn, E, Eschenburg, S, Shuttleworth, W, Schloss, J.V, Amrhein, N, Evans, J.N.S, Kabsch, W. | | Deposit date: | 2000-11-07 | | Release date: | 2001-02-07 | | Last modified: | 2024-02-07 | | Method: | X-RAY DIFFRACTION (1.5 Å) | | Cite: | Interaction of the herbicide glyphosate with its target enzyme 5-enolpyruvylshikimate 3-phosphate synthase in atomic detail.
Proc.Natl.Acad.Sci.USA, 98, 2001
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1RF4
 | | Structural Studies of Streptococcus pneumoniae EPSP Synthase, Tetrahedral intermediate Bound State | | Descriptor: | (3R,4S,5R)-5-{[(1R)-1-CARBOXY-2-FLUORO-1-(PHOSPHONOOXY)ETHYL]OXY}-4-HYDROXY-3-(PHOSPHONOOXY)CYCLOHEX-1-ENE-1-CARBOXYLIC ACID, 5-enolpyruvylshikimate-3-phosphate synthase | | Authors: | Park, H, Hilsenbeck, J.L, Kim, H.J, Shuttleworth, W.A, Park, Y.H, Evans, J.N, Kang, C. | | Deposit date: | 2003-11-07 | | Release date: | 2004-02-17 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.2 Å) | | Cite: | Structural studies of Streptococcus pneumoniae EPSP synthase in unliganded state, tetrahedral intermediate-bound state and S3P-GLP-bound state.
Mol.Microbiol., 51, 2004
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1RF6
 | | Structural Studies of Streptococcus pneumoniae EPSP Synthase in S3P-GLP Bound State | | Descriptor: | 5-enolpyruvylshikimate-3-phosphate synthase, GLYPHOSATE, SHIKIMATE-3-PHOSPHATE | | Authors: | Park, H, Hilsenbeck, J.L, Kim, H.J, Shuttleworth, W.A, Park, Y.H, Evans, J.N, Kang, C. | | Deposit date: | 2003-11-07 | | Release date: | 2004-02-17 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (1.9 Å) | | Cite: | Structural studies of Streptococcus pneumoniae EPSP synthase in unliganded state, tetrahedral intermediate-bound state and S3P-GLP-bound state.
Mol.Microbiol., 51, 2004
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1RF5
 | | Structural Studies of Streptococcus pneumoniae EPSP Synthase in Unliganded State | | Descriptor: | 5-enolpyruvylshikimate-3-phosphate synthase | | Authors: | Park, H, Hilsenbeck, J.L, Kim, H.J, Shuttleworth, W.A, Park, Y.H, Evans, J.N, Kang, C. | | Deposit date: | 2003-11-07 | | Release date: | 2004-02-17 | | Last modified: | 2024-02-14 | | Method: | X-RAY DIFFRACTION (2.3 Å) | | Cite: | Structural studies of Streptococcus pneumoniae EPSP synthase in unliganded state, tetrahedral intermediate-bound state and S3P-GLP-bound state.
Mol.Microbiol., 51, 2004
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