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PDB: 60 results

110D
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ANTHRACYCLINE-DNA INTERACTIONS AT UNFAVOURABLE BASE BASE-PAIR TRIPLET-BINDING SITES: STRUCTURES OF D(CGGCCG)/DAUNOMYCIN AND D(TGGCCA)/ADRIAMYCIN COMPL
Descriptor: DAUNOMYCIN, DNA (5'-D(*CP*GP*GP*CP*CP*G)-3')
Authors:Leonard, G.A, Hambley, T.W, McAuley-Hecht, K, Brown, T, Hunter, W.N.
Deposit date:1993-01-21
Release date:1993-04-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.9 Å)
Cite:Anthracycline-DNA interactions at unfavourable base-pair triplet-binding sites: structures of d(CGGCCG)/daunomycin and d(TGGCCA)/adriamycin complexes.
Acta Crystallogr.,Sect.D, 49, 1993
119D
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CRYSTAL AND MOLECULAR STRUCTURE OF D(CGTAGATCTACG) AT 2.25 ANGSTROMS RESOLUTION
Descriptor: DNA (5'-D(*CP*GP*TP*AP*GP*AP*TP*CP*TP*AP*CP*G)-3'), MAGNESIUM ION
Authors:Leonard, G.A, Hunter, W.N.
Deposit date:1993-04-14
Release date:1993-10-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal and molecular structure of d(CGTAGATCTACG) at 2.25 A resolution.
J.Mol.Biol., 234, 1993
184D
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SELF-ASSOCIATION OF A DNA LOOP CREATES A QUADRUPLEX: CRYSTAL STRUCTURE OF D(GCATGCT) AT 1.8 ANGSTROMS RESOLUTION
Descriptor: DNA (5'-D(*GP*CP*AP*TP*GP*CP*T)-3'), MAGNESIUM ION
Authors:Leonard, G.A, Zhang, S, Peterson, M.R, Harrop, S.J, Helliwell, J.R, Cruse, W.B.T, Langlois D'Estaintot, B, Kennard, O, Brown, T, Hunter, W.N.
Deposit date:1994-08-10
Release date:1995-07-10
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Self-association of a DNA loop creates a quadruplex: crystal structure of d(GCATGCT) at 1.8 A resolution.
Structure, 3, 1995
150D
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GUANINE.1,N6-ETHENOADENINE BASE-PAIRS IN THE CRYSTAL STRUCTURE OF D(CGCGAATT(EDA)GCG)
Descriptor: DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(EDA)P*GP*CP*G)-3'), MAGNESIUM ION
Authors:Leonard, G.A, McAuley-Hecht, K.E, Gibson, N.J, Brown, T, Watson, W.P, Hunter, W.N.
Deposit date:1993-12-02
Release date:1994-05-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Guanine-1,N6-ethenoadenine base pairs in the crystal structure of d(CGCGAATT(epsilon dA)GCG).
Biochemistry, 33, 1994
157D
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CRYSTAL AND MOLECULAR STRUCTURE OF R(CGCGAAUUAGCG): AN RNA DUPLEX CONTAINING TWO G(ANTI).A(ANTI) BASE-PAIRS
Descriptor: RNA (5'-R(*CP*GP*CP*GP*AP*AP*UP*UP*AP*GP*CP*G)-3')
Authors:Leonard, G.A, McAuley-Hecht, K.E, Ebel, S, Lough, D.M, Brown, T, Hunter, W.N.
Deposit date:1994-02-01
Release date:1994-05-31
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:Crystal and molecular structure of r(CGCGAAUUAGCG): an RNA duplex containing two G(anti).A(anti) base pairs.
Structure, 2, 1994
1D81
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THE CONFORMATIONAL VARIABILITY OF AN ADENOSINE. INOSINE BASE-PAIR IN A SYNTHETIC DNA DODECAMER
Descriptor: DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*IP*GP*CP*G)-3')
Authors:Leonard, G.A, Booth, E.D, Hunter, W.N, Brown, T.
Deposit date:1992-07-07
Release date:1992-10-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The conformational variability of an adenosine.inosine base-pair in a synthetic DNA dodecamer.
Nucleic Acids Res., 20, 1992
1D27
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HIGH-RESOLUTION STRUCTURE OF A MUTAGENIC LESION IN DNA
Descriptor: DNA (5'-D(*CP*GP*CP*(6OG)P*AP*AP*TP*TP*TP*GP*CP*G)-3')
Authors:Leonard, G.A, Thomson, J, Watson, W.P, Brown, T.
Deposit date:1991-04-22
Release date:1992-04-07
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2 Å)
Cite:High-resolution structure of a mutagenic lesion in DNA.
Proc.Natl.Acad.Sci.USA, 87, 1990
1D54
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ANTHRACYCLINE BINDING TO DNA: HIGH RESOLUTION STRUCTURE OF D(TGTACA) COMPLEXED WITH 4'-EPIADRIAMYCIN
Descriptor: 4'-EPIDOXORUBICIN, DNA (5'-D(*TP*GP*TP*AP*CP*A)-3')
Authors:Leonard, G.A, Brown, T, Hunter, W.N.
Deposit date:1992-01-06
Release date:1993-04-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.4 Å)
Cite:Anthracycline binding to DNA. High-resolution structure of d(TGTACA) complexed with 4'-epiadriamycin.
Eur.J.Biochem., 204, 1992
1D75
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CONFORMATION OF THE GUANINE.8-OXOADENINE BASE PAIRS IN THE CRYSTAL STRUCTURE OF D(CGCGAATT(O8A)GCG)
Descriptor: DNA (5'-D(*CP*GP*CP*GP*AP*AP*TP*TP*(A38)P*GP*CP*G)-3')
Authors:Leonard, G.A, Guy, A, Brown, T, Teoule, R, Hunter, W.N.
Deposit date:1992-05-07
Release date:1993-01-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.8 Å)
Cite:Conformation of guanine-8-oxoadenine base pairs in the crystal structure of d(CGCGAATT(O8A)GCG).
Biochemistry, 31, 1992
1DA9
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ANTHRACYCLINE-DNA INTERACTIONS AT UNFAVOURABLE BASE BASE-PAIR TRIPLET-BINDING SITES: STRUCTURES OF D(CGGCCG)/DAUNOMYCIN AND D(TGGCCA)/ADRIAMYCIN COMPL
Descriptor: DNA (5'-D(*TP*GP*GP*CP*CP*A)-3'), DOXORUBICIN
Authors:Leonard, G.A, Hambley, T.W, McAuley-Hecht, K, Brown, T, Hunter, W.N.
Deposit date:1993-01-21
Release date:1993-04-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.7 Å)
Cite:Anthracycline-DNA interactions at unfavourable base-pair triplet-binding sites: structures of d(CGGCCG)/daunomycin and d(TGGCCA)/adriamycin complexes.
Acta Crystallogr.,Sect.D, 49, 1993
1OC9
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TRYPAREDOXIN II FROM C.FASCICULATA solved by MR
Descriptor: TRYPAREDOXIN II
Authors:Leonard, G.A, Micossi, E, Hunter, W.N.
Deposit date:2003-02-07
Release date:2003-03-20
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function
J.Biol.Chem., 278, 2003
1OC8
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TRYPAREDOXIN II FROM C.FASCICULATA SOLVED BY MR
Descriptor: SULFATE ION, TRYPAREDOXIN II
Authors:Leonard, G.A, Micossi, E, Hunter, W.N.
Deposit date:2003-02-07
Release date:2003-04-02
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:Tryparedoxins from Crithidia Fasciculata and Trypanosoma Brucei: Photoreduction of the Redox Disulfide Using Synchrotron Radiation and Evidence for a Conformational Switch Implicated in Function
J.Biol.Chem., 278, 2003
1O6J
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Tryparedoxin II from C.fasciculata solved by sulphur phasing
Descriptor: TRYPAREDOXIN II
Authors:Leonard, G.A, Micossi, E, Hunter, W.N.
Deposit date:2002-10-04
Release date:2002-11-07
Last modified:2024-05-08
Method:X-RAY DIFFRACTION (2.35 Å)
Cite:De Novo Phasing of Two Crystal Forms of Tryparedoxin II Using the Anomalous Scattering from S Atoms: A Combination of Small Signal and Medium Resolution Reveals This to be a General Tool for Solving Protein Crystal Structures
Acta Crystallogr.,Sect.D, 58, 2002
1O81
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Tryparedoxin II from C.fasciculata solved by sulphur phasing
Descriptor: SULFATE ION, TRYPAREDOXIN II
Authors:Leonard, G.A, Micossi, E, Hunter, W.N.
Deposit date:2002-11-21
Release date:2002-12-19
Last modified:2019-10-09
Method:X-RAY DIFFRACTION (1.5 Å)
Cite:De Novo Phasing of Two Crystal Forms of Tryparedoxin II Using the Anomalous Scattering from S Atoms: A Combination of Small Signal and Medium Resolution Reveals This to be a General Tool for Solving Protein Crystal Structures
Acta Crystallogr.,Sect.D, 58, 2002
2UYE
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Double mutant Y110S,F111V DntR from Burkholderia sp. strain DNT in complex with thiocyanate
Descriptor: GLYCEROL, REGULATORY PROTEIN, THIOCYANATE ION
Authors:Lonneborg, R, Smirova, I, Dian, C, leonard, G.A, McSweeney, S, Brzezinski, P.
Deposit date:2007-04-04
Release date:2007-08-21
Last modified:2023-12-13
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:In Vivo and in Vitro Investigation of Transcriptional Regulation by Dntr.
J.Mol.Biol., 372, 2007
1N2S
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CRYSTAL STRUCTURE OF DTDP-6-DEOXY-L-LYXO-4-HEXULOSE REDUCTASE (RMLD) IN COMPLEX WITH NADH
Descriptor: 1,4-DIHYDRONICOTINAMIDE ADENINE DINUCLEOTIDE, 2-AMINO-2-HYDROXYMETHYL-PROPANE-1,3-DIOL, MAGNESIUM ION, ...
Authors:Blankenfeldt, W, Kerr, I.D, Giraud, M.F, Mcmiken, H.J, Leonard, G.A, Whitfield, C, Messner, P, Graninger, M, Naismith, J.H.
Deposit date:2002-10-24
Release date:2002-11-01
Last modified:2024-02-14
Method:X-RAY DIFFRACTION (2 Å)
Cite:Variation on a Theme of SDR. dTDP-6-Deoxy-L- lyxo-4-Hexulose Reductase (RmlD) Shows a New Mg(2+)-Dependent Dimerization Mode
Structure, 10, 2002
404D
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CRYSTAL STRUCTURE OF THE RNA/DNA HYBRID R(GAAGAGAAGC). D(GCTTCTCTTC)
Descriptor: 5'-D(*GP*CP*TP*TP*CP*TP*CP*TP*TP*C)-3', 5'-R(*GP*AP*AP*GP*AP*GP*AP*AP*GP*C)-3'
Authors:Conn, G, Brown, T, Leonard, G.A.
Deposit date:1998-06-12
Release date:1998-12-14
Last modified:2023-12-27
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:The crystal structure of the RNA/DNA hybrid r(GAAGAGAAGC). d(GCTTCTCTTC) shows significant differences to that found in solution.
Nucleic Acids Res., 27, 1999
111D
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CRYSTAL STRUCTURE AND STABILITY OF A DNA DUPLEX CONTAINING A(ANTI).G(SYN) BASE-PAIRS
Descriptor: DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*GP*GP*CP*G)-3')
Authors:Brown, T, Leonard, G.A, Booth, E.D, Chambers, J.
Deposit date:1993-01-04
Release date:1993-07-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.25 Å)
Cite:Crystal structure and stability of a DNA duplex containing A(anti).G(syn) base-pairs.
J.Mol.Biol., 207, 1989
133D
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THE CRYSTAL STRUCTURE OF N4-METHYLCYTOSINE.GUANOSIN BASE-PAIRS IN THE SYNTHETIC HEXANUCLEOTIDE D(CGCGM(4)CG)
Descriptor: DNA (5'-D(*CP*GP*CP*GP*(C34)P*G)-3')
Authors:Cervi, A.R, Guy, A, Leonard, G.A, Teoule, R, Hunter, W.N.
Deposit date:1993-07-29
Release date:1994-01-15
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (1.8 Å)
Cite:The crystal structure of N4-methylcytosine.guanosine base-pairs in the synthetic hexanucleotide d(CGCGm4CG).
Nucleic Acids Res., 21, 1993
178D
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CRYSTAL STRUCTURE OF A DNA DUPLEX CONTAINING 8-HYDROXYDEOXYGUANINE.ADENINE BASE-PAIRS
Descriptor: DNA (5'-D(*CP*GP*CP*AP*AP*AP*TP*TP*(8OG)P*GP*CP*G)-3')
Authors:McAuley-Hecht, K.E, Leonard, G.A, Gibson, N.J, Thomson, J.B, Watson, W.P, Hunter, W.N, Brown, T.
Deposit date:1994-05-19
Release date:1994-10-04
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.5 Å)
Cite:Crystal structure of a DNA duplex containing 8-hydroxydeoxyguanine-adenine base pairs.
Biochemistry, 33, 1994
1JNF
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Rabbit serum transferrin at 2.6 A resolution.
Descriptor: CARBONATE ION, CHLORIDE ION, FE (III) ION, ...
Authors:Hall, D.R, Hadden, J.M, Leonard, G.A, Bailey, S, Neu, M, Winn, M, Lindley, P.F.
Deposit date:2001-07-24
Release date:2001-08-01
Last modified:2024-04-03
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:The crystal and molecular structures of diferric porcine and rabbit serum transferrins at resolutions of 2.15 and 2.60 A, respectively.
Acta Crystallogr.,Sect.D, 58, 2002
1KC1
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Crystal structure of dTDP-6-deoxy-L-lyxo-4-hexulose reductase (RmlD) in complex with NADPH
Descriptor: MAGNESIUM ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, SULFATE ION, ...
Authors:Blankenfeldt, W, Kerr, I.D, Giraud, M.F, McMiken, H.J, Leonard, G.A, Whitfield, C, Messner, P, Graninger, M, Naismith, J.H.
Deposit date:2001-11-07
Release date:2002-06-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.6 Å)
Cite:Variation on a theme of SDR. dTDP-6-deoxy-L- lyxo-4-hexulose reductase (RmlD) shows a new Mg2+-dependent dimerization mode.
Structure, 10, 2002
1KBZ
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Crystal Structure of apo-dTDP-6-deoxy-L-lyxo-4-hexulose reductase (RmlD) from Salmonella enterica serovar Typhimurium
Descriptor: MAGNESIUM ION, dTDP-glucose oxidoreductase
Authors:Blankenfeldt, W, Kerr, I.D, Giraud, M.F, McMiken, H.J, Leonard, G.A, Whitfield, C, Messner, P, Graninger, M, Naismith, J.H.
Deposit date:2001-11-07
Release date:2002-06-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.2 Å)
Cite:Variation on a theme of SDR. dTDP-6-deoxy-L- lyxo-4-hexulose reductase (RmlD) shows a new Mg2+-dependent dimerization mode.
Structure, 10, 2002
1KC3
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Crystal structure of dTDP-6-deoxy-L-lyxo-4-hexulose reductase (RmlD) in complex with NADPH and dTDP-L-rhamnose
Descriptor: 2'-DEOXY-THYMIDINE-BETA-L-RHAMNOSE, MAGNESIUM ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ...
Authors:Blankenfeldt, W, Kerr, I.D, Giraud, M.F, McMiken, H.J, Leonard, G.A, Whitfield, C, Messner, P, Graninger, M, Naismith, J.H.
Deposit date:2001-11-07
Release date:2002-06-28
Last modified:2024-02-07
Method:X-RAY DIFFRACTION (2.7 Å)
Cite:Variation on a theme of SDR. dTDP-6-deoxy-L- lyxo-4-hexulose reductase (RmlD) shows a new Mg2+-dependent dimerization mode.
Structure, 10, 2002
2PK9
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Structure of the Pho85-Pho80 CDK-cyclin Complex of the Phosphate-responsive Signal Transduction Pathway
Descriptor: 2-(N-MORPHOLINO)-ETHANESULFONIC ACID, Cyclin-dependent protein kinase PHO85, PHO85 cyclin PHO80
Authors:Huang, K, Ferrin-O'Connell, I, Zhang, W, Leonard, G.A, O'Shea, E.K, Quiocho, F.A.
Deposit date:2007-04-17
Release date:2007-12-11
Last modified:2024-02-21
Method:X-RAY DIFFRACTION (2.906 Å)
Cite:Structure of the Pho85-Pho80 CDK-Cyclin Complex of the Phosphate-Responsive Signal Transduction Pathway
Mol.Cell, 28, 2007

 

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