1KC3

Crystal structure of dTDP-6-deoxy-L-lyxo-4-hexulose reductase (RmlD) in complex with NADPH and dTDP-L-rhamnose

Summary for 1KC3

Entry DOI	10.2210/pdb1kc3/pdb
Related	1KBZ 1KC0 1KC1
Descriptor	dTDP-glucose oxidoreductase, MAGNESIUM ION, NADPH DIHYDRO-NICOTINAMIDE-ADENINE-DINUCLEOTIDE PHOSPHATE, ... (5 entities in total)
Functional Keywords	rossman-fold, sugar-nucleotide-binding domain, oxidoreductase
Biological source	Salmonella typhimurium
Total number of polymer chains	1
Total formula weight	33908.00
Authors	Blankenfeldt, W.,Kerr, I.D.,Giraud, M.F.,McMiken, H.J.,Leonard, G.A.,Whitfield, C.,Messner, P.,Graninger, M.,Naismith, J.H. (deposition date: 2001-11-07, release date: 2002-06-28, Last modification date: 2024-02-07)
Primary citation	Blankenfeldt, W.,Kerr, I.D.,Giraud, M.F.,McMiken, H.J.,Leonard, G.,Whitfield, C.,Messner, P.,Graninger, M.,Naismith, J.H. Variation on a theme of SDR. dTDP-6-deoxy-L- lyxo-4-hexulose reductase (RmlD) shows a new Mg2+-dependent dimerization mode. Structure, 10:773-786, 2002 Cited by PubMed: 12057193 DOI: 10.1016/S0969-2126(02)00770-0 PDB entries with the same primary citation
Experimental method	X-RAY DIFFRACTION (2.7 Å)

Structure validation