1KC1

Crystal structure of dTDP-6-deoxy-L-lyxo-4-hexulose reductase (RmlD) in complex with NADPH

Summary for 1KC1

• Entry DOI: 10.2210/pdb1kc1/pdb
• Related: 1KBZ 1KC0 1KC3
• Descriptor: dTDP-glucose oxidoreductase, MAGNESIUM ION, SULFATE ION, ... (5 entities in total)
• Functional Keywords: rossman-fold, sugar-nucleotide-binding domain, oxidoreductase
• Biological source: Salmonella typhimurium
• Total number of polymer chains: 1
• Total formula weight: 33455.73

Authors

Blankenfeldt, W.,Kerr, I.D.,Giraud, M.F.,McMiken, H.J.,Leonard, G.A.,Whitfield, C.,Messner, P.,Graninger, M.,Naismith, J.H. (deposition date: 2001-11-07, release date: 2002-06-28, Last modification date: 2024-02-07)

• Primary citation: Blankenfeldt, W.,Kerr, I.D.,Giraud, M.F.,McMiken, H.J.,Leonard, G.,Whitfield, C.,Messner, P.,Graninger, M.,Naismith, J.H.; Variation on a theme of SDR. dTDP-6-deoxy-L- lyxo-4-hexulose reductase (RmlD) shows a new Mg2+-dependent dimerization mode.; Structure, 10:773-786, 2002; PubMed: 12057193; DOI: 10.1016/S0969-2126(02)00770-0

Experimental method

X-RAY DIFFRACTION (2.6 Å)